Add or remove parameters in the intervals of a PKNCAdata object

Add or remove parameters in the intervals of a PKNCAdata object

Usage

interval_add_param(
  data,
  param = NULL,
  param_pattern = NULL,
  target_groups = NULL,
  ...
)

interval_remove_param(
  data,
  param = NULL,
  param_pattern = NULL,
  target_groups = NULL,
  ...
)

Arguments

data

A PKNCAdata object or a data.frame of intervals.

param

A character vector of NCA parameter names.

param_pattern

A character vector of regular expressions matching NCA parameter names. One or both of param and param_pattern must be given.

target_groups

A data.frame of group values restricting the change to matching intervals. Every column must match (and) for at least one row of target_groups (or). NULL (the default) applies the change to all intervals.

...

Ignored.

Value

The input with the parameters added or removed.

See also

interval_add_impute(), get.interval.cols()

Other Interval specifications: add.interval.col(), check.interval.specification(), choose.auc.intervals(), get.interval.cols(), get.parameter.deps(), interval_add_impute(), interval_add_secondary(), pknca_check_parameter_classification(), pknca_concepts(), pknca_interval_table(), pknca_parameter_table(), pknca_presets(), pknca_ref()

Examples

intervals <- data.frame(start = 0, end = 24, cmax = TRUE, tmax = TRUE)
interval_add_param(intervals, param = c("auclast", "half.life"))
#>   start end cmax tmax auclast half.life
#> 1     0  24 TRUE TRUE    TRUE      TRUE
# At least one parameter must remain, so removing every one is an error
interval_remove_param(intervals, param_pattern = "^tmax$")
#>   start end cmax  tmax
#> 1     0  24 TRUE FALSE