Get the columns that can be used in an interval specification
Source:R/001-add.interval.col.R
get.interval.cols.RdGet the columns that can be used in an interval specification
Value
A list with named elements for each parameter. Each list element contains the parameter definition.
See also
check.interval.specification() and the vignette "Selection of
Calculation Intervals"
Other Interval specifications:
add.interval.col(),
check.interval.specification(),
choose.auc.intervals(),
get.parameter.deps()
Examples
get.interval.cols()
#> $start
#> $start$FUN
#> [1] NA
#>
#> $start$values
#> function (x, ...) .Primitive("as.double")
#>
#> $start$unit_type
#> [1] "time"
#>
#> $start$pretty_name
#> [1] "Interval Start"
#>
#> $start$desc
#> [1] "Starting time of the interval"
#>
#> $start$sparse
#> [1] FALSE
#>
#> $start$formalsmap
#> list()
#>
#> $start$depends
#> NULL
#>
#> $start$datatype
#> [1] "interval"
#>
#> $start$pptestcd_cdisc
#> [1] "start"
#>
#> $start$pptest_cdisc
#> [1] "Starting time of the interval"
#>
#>
#> $end
#> $end$FUN
#> [1] NA
#>
#> $end$values
#> function (x, ...) .Primitive("as.double")
#>
#> $end$unit_type
#> [1] "time"
#>
#> $end$pretty_name
#> [1] "Interval End"
#>
#> $end$desc
#> [1] "End time of interval (may be Inf)"
#>
#> $end$sparse
#> [1] FALSE
#>
#> $end$formalsmap
#> list()
#>
#> $end$depends
#> NULL
#>
#> $end$datatype
#> [1] "interval"
#>
#> $end$pptestcd_cdisc
#> [1] "end"
#>
#> $end$pptest_cdisc
#> [1] "End time of interval (may be Inf)"
#>
#>
#> $auclast
#> $auclast$FUN
#> [1] "pk.calc.auc.last"
#>
#> $auclast$values
#> [1] FALSE TRUE
#>
#> $auclast$unit_type
#> [1] "auc"
#>
#> $auclast$pretty_name
#> [1] "AUClast"
#>
#> $auclast$desc
#> [1] "AUC start to last conc above LOQ"
#>
#> $auclast$sparse
#> [1] FALSE
#>
#> $auclast$formalsmap
#> list()
#>
#> $auclast$depends
#> NULL
#>
#> $auclast$datatype
#> [1] "interval"
#>
#> $auclast$pptestcd_cdisc
#> [1] "AUCLST"
#>
#> $auclast$pptest_cdisc
#> [1] "AUC to Last Nonzero Conc"
#>
#>
#> $aucall
#> $aucall$FUN
#> [1] "pk.calc.auc.all"
#>
#> $aucall$values
#> [1] FALSE TRUE
#>
#> $aucall$unit_type
#> [1] "auc"
#>
#> $aucall$pretty_name
#> [1] "AUCall"
#>
#> $aucall$desc
#> [1] "AUClast plus triangle, 0 at BLQ"
#>
#> $aucall$sparse
#> [1] FALSE
#>
#> $aucall$formalsmap
#> list()
#>
#> $aucall$depends
#> NULL
#>
#> $aucall$datatype
#> [1] "interval"
#>
#> $aucall$pptestcd_cdisc
#> [1] "AUCALL"
#>
#> $aucall$pptest_cdisc
#> [1] "AUC All"
#>
#>
#> $aumclast
#> $aumclast$FUN
#> [1] "pk.calc.aumc.last"
#>
#> $aumclast$values
#> [1] FALSE TRUE
#>
#> $aumclast$unit_type
#> [1] "aumc"
#>
#> $aumclast$pretty_name
#> [1] "AUMC,last"
#>
#> $aumclast$desc
#> [1] "AUMC start to last conc above LOQ"
#>
#> $aumclast$sparse
#> [1] FALSE
#>
#> $aumclast$formalsmap
#> list()
#>
#> $aumclast$depends
#> NULL
#>
#> $aumclast$datatype
#> [1] "interval"
#>
#> $aumclast$pptestcd_cdisc
#> [1] "AUMCLST"
#>
#> $aumclast$pptest_cdisc
#> [1] "AUMC to Last Nonzero Conc"
#>
#>
#> $aumcall
#> $aumcall$FUN
#> [1] "pk.calc.aumc.all"
#>
#> $aumcall$values
#> [1] FALSE TRUE
#>
#> $aumcall$unit_type
#> [1] "aumc"
#>
#> $aumcall$pretty_name
#> [1] "AUMC,all"
#>
#> $aumcall$desc
#> [1] "AUMClast plus triangle moment, 0 at BLQ"
#>
#> $aumcall$sparse
#> [1] FALSE
#>
#> $aumcall$formalsmap
#> list()
#>
#> $aumcall$depends
#> NULL
#>
#> $aumcall$datatype
#> [1] "interval"
#>
#> $aumcall$pptestcd_cdisc
#> [1] "AUMCALL"
#>
#> $aumcall$pptest_cdisc
#> [1] "AUMC All"
#>
#>
#> $aucint.last
#> $aucint.last$FUN
#> [1] "pk.calc.aucint.last"
#>
#> $aucint.last$values
#> [1] FALSE TRUE
#>
#> $aucint.last$unit_type
#> [1] "auc"
#>
#> $aucint.last$pretty_name
#> [1] "AUCint (based on AUClast extrapolation)"
#>
#> $aucint.last$desc
#> [1] "AUC from T1 to T2 (zero extrap)"
#>
#> $aucint.last$sparse
#> [1] FALSE
#>
#> $aucint.last$formalsmap
#> $aucint.last$formalsmap$conc
#> [1] "conc.group"
#>
#> $aucint.last$formalsmap$time
#> [1] "time.group"
#>
#> $aucint.last$formalsmap$time.dose
#> NULL
#>
#>
#> $aucint.last$depends
#> NULL
#>
#> $aucint.last$datatype
#> [1] "interval"
#>
#> $aucint.last$pptestcd_cdisc
#> [1] "AUCINT"
#>
#> $aucint.last$pptest_cdisc
#> [1] "AUC from T1 to T2"
#>
#>
#> $aucint.last.dose
#> $aucint.last.dose$FUN
#> [1] "pk.calc.aucint.last"
#>
#> $aucint.last.dose$values
#> [1] FALSE TRUE
#>
#> $aucint.last.dose$unit_type
#> [1] "auc"
#>
#> $aucint.last.dose$pretty_name
#> [1] "AUCint (based on AUClast extrapolation, dose-aware)"
#>
#> $aucint.last.dose$desc
#> [1] "AUC T1 to T2, dose-aware (zero extrap)"
#>
#> $aucint.last.dose$sparse
#> [1] FALSE
#>
#> $aucint.last.dose$formalsmap
#> $aucint.last.dose$formalsmap$conc
#> [1] "conc.group"
#>
#> $aucint.last.dose$formalsmap$time
#> [1] "time.group"
#>
#> $aucint.last.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#>
#>
#> $aucint.last.dose$depends
#> NULL
#>
#> $aucint.last.dose$datatype
#> [1] "interval"
#>
#> $aucint.last.dose$pptestcd_cdisc
#> [1] "AUCINTD"
#>
#> $aucint.last.dose$pptest_cdisc
#> [1] "AUC from T1 to T2 Normalized by Dose"
#>
#>
#> $aucint.all
#> $aucint.all$FUN
#> [1] "pk.calc.aucint.all"
#>
#> $aucint.all$values
#> [1] FALSE TRUE
#>
#> $aucint.all$unit_type
#> [1] "auc"
#>
#> $aucint.all$pretty_name
#> [1] "AUCint (based on AUCall extrapolation)"
#>
#> $aucint.all$desc
#> [1] "AUC from T1 to T2 (AUCall extrap)"
#>
#> $aucint.all$sparse
#> [1] FALSE
#>
#> $aucint.all$formalsmap
#> $aucint.all$formalsmap$conc
#> [1] "conc.group"
#>
#> $aucint.all$formalsmap$time
#> [1] "time.group"
#>
#> $aucint.all$formalsmap$time.dose
#> NULL
#>
#>
#> $aucint.all$depends
#> NULL
#>
#> $aucint.all$datatype
#> [1] "interval"
#>
#> $aucint.all$pptestcd_cdisc
#> [1] "AUCINTA"
#>
#> $aucint.all$pptest_cdisc
#> [1] "AUCint (based on AUCall extrapolation)"
#>
#>
#> $aucint.all.dose
#> $aucint.all.dose$FUN
#> [1] "pk.calc.aucint.all"
#>
#> $aucint.all.dose$values
#> [1] FALSE TRUE
#>
#> $aucint.all.dose$unit_type
#> [1] "auc"
#>
#> $aucint.all.dose$pretty_name
#> [1] "AUCint (based on AUCall extrapolation, dose-aware)"
#>
#> $aucint.all.dose$desc
#> [1] "AUC T1 to T2, dose-aware (AUCall)"
#>
#> $aucint.all.dose$sparse
#> [1] FALSE
#>
#> $aucint.all.dose$formalsmap
#> $aucint.all.dose$formalsmap$conc
#> [1] "conc.group"
#>
#> $aucint.all.dose$formalsmap$time
#> [1] "time.group"
#>
#> $aucint.all.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#>
#>
#> $aucint.all.dose$depends
#> NULL
#>
#> $aucint.all.dose$datatype
#> [1] "interval"
#>
#> $aucint.all.dose$pptestcd_cdisc
#> [1] "AUCINTAD"
#>
#> $aucint.all.dose$pptest_cdisc
#> [1] "AUCint (based on AUCall extrapolation, dose-aware)"
#>
#>
#> $aumcint.last
#> $aumcint.last$FUN
#> [1] "pk.calc.aumcint.last"
#>
#> $aumcint.last$values
#> [1] FALSE TRUE
#>
#> $aumcint.last$unit_type
#> [1] "aumc"
#>
#> $aumcint.last$pretty_name
#> [1] "AUMCint (based on AUMClast extrapolation)"
#>
#> $aumcint.last$desc
#> [1] "AUMC from T1 to T2 (zero extrap)"
#>
#> $aumcint.last$sparse
#> [1] FALSE
#>
#> $aumcint.last$formalsmap
#> $aumcint.last$formalsmap$conc
#> [1] "conc.group"
#>
#> $aumcint.last$formalsmap$time
#> [1] "time.group"
#>
#> $aumcint.last$formalsmap$time.dose
#> NULL
#>
#>
#> $aumcint.last$depends
#> NULL
#>
#> $aumcint.last$datatype
#> [1] "interval"
#>
#> $aumcint.last$pptestcd_cdisc
#> [1] "aumcint.last"
#>
#> $aumcint.last$pptest_cdisc
#> [1] "AUMC from T1 to T2 (zero extrap)"
#>
#>
#> $aumcint.last.dose
#> $aumcint.last.dose$FUN
#> [1] "pk.calc.aumcint.last"
#>
#> $aumcint.last.dose$values
#> [1] FALSE TRUE
#>
#> $aumcint.last.dose$unit_type
#> [1] "aumc"
#>
#> $aumcint.last.dose$pretty_name
#> [1] "AUMCint (based on AUMClast extrapolation, dose-aware)"
#>
#> $aumcint.last.dose$desc
#> [1] "AUMC T1 to T2, dose-aware (zero extrap)"
#>
#> $aumcint.last.dose$sparse
#> [1] FALSE
#>
#> $aumcint.last.dose$formalsmap
#> $aumcint.last.dose$formalsmap$conc
#> [1] "conc.group"
#>
#> $aumcint.last.dose$formalsmap$time
#> [1] "time.group"
#>
#> $aumcint.last.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#>
#>
#> $aumcint.last.dose$depends
#> NULL
#>
#> $aumcint.last.dose$datatype
#> [1] "interval"
#>
#> $aumcint.last.dose$pptestcd_cdisc
#> [1] "aumcint.last.dose"
#>
#> $aumcint.last.dose$pptest_cdisc
#> [1] "AUMC T1 to T2, dose-aware (zero extrap)"
#>
#>
#> $aumcint.all
#> $aumcint.all$FUN
#> [1] "pk.calc.aumcint.all"
#>
#> $aumcint.all$values
#> [1] FALSE TRUE
#>
#> $aumcint.all$unit_type
#> [1] "aumc"
#>
#> $aumcint.all$pretty_name
#> [1] "AUMCint (based on AUMCall extrapolation)"
#>
#> $aumcint.all$desc
#> [1] "AUMC from T1 to T2 (AUMCall extrap)"
#>
#> $aumcint.all$sparse
#> [1] FALSE
#>
#> $aumcint.all$formalsmap
#> $aumcint.all$formalsmap$conc
#> [1] "conc.group"
#>
#> $aumcint.all$formalsmap$time
#> [1] "time.group"
#>
#> $aumcint.all$formalsmap$time.dose
#> NULL
#>
#>
#> $aumcint.all$depends
#> NULL
#>
#> $aumcint.all$datatype
#> [1] "interval"
#>
#> $aumcint.all$pptestcd_cdisc
#> [1] "aumcint.all"
#>
#> $aumcint.all$pptest_cdisc
#> [1] "AUMC from T1 to T2 (AUMCall extrap)"
#>
#>
#> $aumcint.all.dose
#> $aumcint.all.dose$FUN
#> [1] "pk.calc.aumcint.all"
#>
#> $aumcint.all.dose$values
#> [1] FALSE TRUE
#>
#> $aumcint.all.dose$unit_type
#> [1] "aumc"
#>
#> $aumcint.all.dose$pretty_name
#> [1] "AUMCint (based on AUMCall extrapolation, dose-aware)"
#>
#> $aumcint.all.dose$desc
#> [1] "AUMC T1 to T2, dose-aware (AUMCall)"
#>
#> $aumcint.all.dose$sparse
#> [1] FALSE
#>
#> $aumcint.all.dose$formalsmap
#> $aumcint.all.dose$formalsmap$conc
#> [1] "conc.group"
#>
#> $aumcint.all.dose$formalsmap$time
#> [1] "time.group"
#>
#> $aumcint.all.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#>
#>
#> $aumcint.all.dose$depends
#> NULL
#>
#> $aumcint.all.dose$datatype
#> [1] "interval"
#>
#> $aumcint.all.dose$pptestcd_cdisc
#> [1] "aumcint.all.dose"
#>
#> $aumcint.all.dose$pptest_cdisc
#> [1] "AUMC T1 to T2, dose-aware (AUMCall)"
#>
#>
#> $c0
#> $c0$FUN
#> [1] "pk.calc.c0"
#>
#> $c0$values
#> [1] FALSE TRUE
#>
#> $c0$unit_type
#> [1] "conc"
#>
#> $c0$pretty_name
#> [1] "C0"
#>
#> $c0$desc
#> [1] "Initial conc after IV bolus"
#>
#> $c0$sparse
#> [1] FALSE
#>
#> $c0$formalsmap
#> list()
#>
#> $c0$depends
#> NULL
#>
#> $c0$datatype
#> [1] "interval"
#>
#> $c0$pptestcd_cdisc
#> [1] "C0"
#>
#> $c0$pptest_cdisc
#> [1] "Initial Conc"
#>
#>
#> $cmax
#> $cmax$FUN
#> [1] "pk.calc.cmax"
#>
#> $cmax$values
#> [1] FALSE TRUE
#>
#> $cmax$unit_type
#> [1] "conc"
#>
#> $cmax$pretty_name
#> [1] "Cmax"
#>
#> $cmax$desc
#> [1] "Maximum observed concentration"
#>
#> $cmax$sparse
#> [1] FALSE
#>
#> $cmax$formalsmap
#> list()
#>
#> $cmax$depends
#> NULL
#>
#> $cmax$datatype
#> [1] "interval"
#>
#> $cmax$pptestcd_cdisc
#> [1] "CMAX"
#>
#> $cmax$pptest_cdisc
#> [1] "Max Conc"
#>
#>
#> $cmin
#> $cmin$FUN
#> [1] "pk.calc.cmin"
#>
#> $cmin$values
#> [1] FALSE TRUE
#>
#> $cmin$unit_type
#> [1] "conc"
#>
#> $cmin$pretty_name
#> [1] "Cmin"
#>
#> $cmin$desc
#> [1] "Minimum observed concentration"
#>
#> $cmin$sparse
#> [1] FALSE
#>
#> $cmin$formalsmap
#> list()
#>
#> $cmin$depends
#> NULL
#>
#> $cmin$datatype
#> [1] "interval"
#>
#> $cmin$pptestcd_cdisc
#> [1] "CMIN"
#>
#> $cmin$pptest_cdisc
#> [1] "Min Conc"
#>
#>
#> $tmax
#> $tmax$FUN
#> [1] "pk.calc.tmax"
#>
#> $tmax$values
#> [1] FALSE TRUE
#>
#> $tmax$unit_type
#> [1] "time"
#>
#> $tmax$pretty_name
#> [1] "Tmax"
#>
#> $tmax$desc
#> [1] "Time of maximum observed conc"
#>
#> $tmax$sparse
#> [1] FALSE
#>
#> $tmax$formalsmap
#> list()
#>
#> $tmax$depends
#> NULL
#>
#> $tmax$datatype
#> [1] "interval"
#>
#> $tmax$pptestcd_cdisc
#> [1] "TMAX"
#>
#> $tmax$pptest_cdisc
#> [1] "Time of CMAX"
#>
#>
#> $tmin
#> $tmin$FUN
#> [1] "pk.calc.tmin"
#>
#> $tmin$values
#> [1] FALSE TRUE
#>
#> $tmin$unit_type
#> [1] "time"
#>
#> $tmin$pretty_name
#> [1] "Tmin"
#>
#> $tmin$desc
#> [1] "Time of minimum observed conc"
#>
#> $tmin$sparse
#> [1] FALSE
#>
#> $tmin$formalsmap
#> list()
#>
#> $tmin$depends
#> NULL
#>
#> $tmin$datatype
#> [1] "interval"
#>
#> $tmin$pptestcd_cdisc
#> [1] "TMIN"
#>
#> $tmin$pptest_cdisc
#> [1] "Time of CMIN Observation"
#>
#>
#> $tlast
#> $tlast$FUN
#> [1] "pk.calc.tlast"
#>
#> $tlast$values
#> [1] FALSE TRUE
#>
#> $tlast$unit_type
#> [1] "time"
#>
#> $tlast$pretty_name
#> [1] "Tlast"
#>
#> $tlast$desc
#> [1] "Time of last conc above LOQ"
#>
#> $tlast$sparse
#> [1] FALSE
#>
#> $tlast$formalsmap
#> list()
#>
#> $tlast$depends
#> NULL
#>
#> $tlast$datatype
#> [1] "interval"
#>
#> $tlast$pptestcd_cdisc
#> [1] "TLST"
#>
#> $tlast$pptest_cdisc
#> [1] "Time of Last Nonzero Conc"
#>
#>
#> $tfirst
#> $tfirst$FUN
#> [1] "pk.calc.tfirst"
#>
#> $tfirst$values
#> [1] FALSE TRUE
#>
#> $tfirst$unit_type
#> [1] "time"
#>
#> $tfirst$pretty_name
#> [1] "Tfirst"
#>
#> $tfirst$desc
#> [1] "Time of first conc above LOQ"
#>
#> $tfirst$sparse
#> [1] FALSE
#>
#> $tfirst$formalsmap
#> list()
#>
#> $tfirst$depends
#> NULL
#>
#> $tfirst$datatype
#> [1] "interval"
#>
#> $tfirst$pptestcd_cdisc
#> [1] "TFIRST"
#>
#> $tfirst$pptest_cdisc
#> [1] "Time of First Nonzero Conc"
#>
#>
#> $clast.obs
#> $clast.obs$FUN
#> [1] "pk.calc.clast.obs"
#>
#> $clast.obs$values
#> [1] FALSE TRUE
#>
#> $clast.obs$unit_type
#> [1] "conc"
#>
#> $clast.obs$pretty_name
#> [1] "Clast"
#>
#> $clast.obs$desc
#> [1] "Last conc observed above LOQ"
#>
#> $clast.obs$sparse
#> [1] FALSE
#>
#> $clast.obs$formalsmap
#> list()
#>
#> $clast.obs$depends
#> NULL
#>
#> $clast.obs$datatype
#> [1] "interval"
#>
#> $clast.obs$pptestcd_cdisc
#> [1] "CLST"
#>
#> $clast.obs$pptest_cdisc
#> [1] "Last Nonzero Conc"
#>
#>
#> $cl.last
#> $cl.last$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.last$values
#> [1] FALSE TRUE
#>
#> $cl.last$unit_type
#> [1] "clearance"
#>
#> $cl.last$pretty_name
#> [1] "CL (based on AUClast)"
#>
#> $cl.last$desc
#> [1] "Clearance, AUClast"
#>
#> $cl.last$sparse
#> [1] FALSE
#>
#> $cl.last$formalsmap
#> $cl.last$formalsmap$auc
#> [1] "auclast"
#>
#>
#> $cl.last$depends
#> [1] "auclast"
#>
#> $cl.last$datatype
#> [1] "interval"
#>
#> $cl.last$pptestcd_cdisc
#> $cl.last$pptestcd_cdisc$route
#> $cl.last$pptestcd_cdisc$route$extravascular
#> [1] "CLF/FLST"
#>
#> $cl.last$pptestcd_cdisc$route$intravascular
#> [1] "CLLST"
#>
#>
#>
#> $cl.last$pptest_cdisc
#> $cl.last$pptest_cdisc$route
#> $cl.last$pptest_cdisc$route$extravascular
#> [1] "CL by F (based on AUClast)"
#>
#> $cl.last$pptest_cdisc$route$intravascular
#> [1] "CL (based on AUClast)"
#>
#>
#>
#>
#> $cl.all
#> $cl.all$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.all$values
#> [1] FALSE TRUE
#>
#> $cl.all$unit_type
#> [1] "clearance"
#>
#> $cl.all$pretty_name
#> [1] "CL (based on AUCall)"
#>
#> $cl.all$desc
#> [1] "Clearance, AUCall"
#>
#> $cl.all$sparse
#> [1] FALSE
#>
#> $cl.all$formalsmap
#> $cl.all$formalsmap$auc
#> [1] "aucall"
#>
#>
#> $cl.all$depends
#> [1] "aucall"
#>
#> $cl.all$datatype
#> [1] "interval"
#>
#> $cl.all$pptestcd_cdisc
#> $cl.all$pptestcd_cdisc$route
#> $cl.all$pptestcd_cdisc$route$extravascular
#> [1] "CLF/FALL"
#>
#> $cl.all$pptestcd_cdisc$route$intravascular
#> [1] "CLALL"
#>
#>
#>
#> $cl.all$pptest_cdisc
#> $cl.all$pptest_cdisc$route
#> $cl.all$pptest_cdisc$route$extravascular
#> [1] "CL by F (based on AUCall)"
#>
#> $cl.all$pptest_cdisc$route$intravascular
#> [1] "CL (based on AUCall)"
#>
#>
#>
#>
#> $cl.int.all
#> $cl.int.all$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.int.all$values
#> [1] FALSE TRUE
#>
#> $cl.int.all$unit_type
#> [1] "clearance"
#>
#> $cl.int.all$pretty_name
#> [1] "CL (based on AUCint.all)"
#>
#> $cl.int.all$desc
#> [1] "Clearance, AUCint.all"
#>
#> $cl.int.all$sparse
#> [1] FALSE
#>
#> $cl.int.all$formalsmap
#> $cl.int.all$formalsmap$auc
#> [1] "aucint.all"
#>
#>
#> $cl.int.all$depends
#> [1] "aucint.all"
#>
#> $cl.int.all$datatype
#> [1] "interval"
#>
#> $cl.int.all$pptestcd_cdisc
#> [1] "cl.int.all"
#>
#> $cl.int.all$pptest_cdisc
#> [1] "Clearance, AUCint.all"
#>
#>
#> $cl.int.last
#> $cl.int.last$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.int.last$values
#> [1] FALSE TRUE
#>
#> $cl.int.last$unit_type
#> [1] "clearance"
#>
#> $cl.int.last$pretty_name
#> [1] "CL (based on AUCint.last)"
#>
#> $cl.int.last$desc
#> [1] "Clearance, AUCint.last"
#>
#> $cl.int.last$sparse
#> [1] FALSE
#>
#> $cl.int.last$formalsmap
#> $cl.int.last$formalsmap$auc
#> [1] "aucint.last"
#>
#>
#> $cl.int.last$depends
#> [1] "aucint.last"
#>
#> $cl.int.last$datatype
#> [1] "interval"
#>
#> $cl.int.last$pptestcd_cdisc
#> [1] "cl.int.last"
#>
#> $cl.int.last$pptest_cdisc
#> [1] "Clearance, AUCint.last"
#>
#>
#> $f
#> $f$FUN
#> [1] "pk.calc.f"
#>
#> $f$values
#> [1] FALSE TRUE
#>
#> $f$unit_type
#> [1] "fraction"
#>
#> $f$pretty_name
#> [1] "Bioavailability"
#>
#> $f$desc
#> [1] "Bioavailability (absolute or relative)"
#>
#> $f$sparse
#> [1] FALSE
#>
#> $f$formalsmap
#> list()
#>
#> $f$depends
#> NULL
#>
#> $f$datatype
#> [1] "interval"
#>
#> $f$pptestcd_cdisc
#> [1] "FAB"
#>
#> $f$pptest_cdisc
#> [1] "Absolute Bioavailability"
#>
#>
#> $mrt.last
#> $mrt.last$FUN
#> [1] "pk.calc.mrt"
#>
#> $mrt.last$values
#> [1] FALSE TRUE
#>
#> $mrt.last$unit_type
#> [1] "time"
#>
#> $mrt.last$pretty_name
#> [1] "MRT (based on AUClast)"
#>
#> $mrt.last$desc
#> [1] "MRT, AUClast/AUMClast"
#>
#> $mrt.last$sparse
#> [1] FALSE
#>
#> $mrt.last$formalsmap
#> $mrt.last$formalsmap$auc
#> [1] "auclast"
#>
#> $mrt.last$formalsmap$aumc
#> [1] "aumclast"
#>
#>
#> $mrt.last$depends
#> [1] "auclast" "aumclast"
#>
#> $mrt.last$datatype
#> [1] "interval"
#>
#> $mrt.last$pptestcd_cdisc
#> $mrt.last$pptestcd_cdisc$route
#> $mrt.last$pptestcd_cdisc$route$extravascular
#> [1] "MRTEVLST"
#>
#> $mrt.last$pptestcd_cdisc$route$intravascular
#> [1] "MRTICLST"
#>
#>
#>
#> $mrt.last$pptest_cdisc
#> $mrt.last$pptest_cdisc$route
#> $mrt.last$pptest_cdisc$route$extravascular
#> [1] "MRT Extravasc to Last Nonzero Conc"
#>
#> $mrt.last$pptest_cdisc$route$intravascular
#> [1] "MRT IV Cont Inf to Last Nonzero Conc"
#>
#>
#>
#>
#> $mrt.all
#> $mrt.all$FUN
#> [1] "pk.calc.mrt"
#>
#> $mrt.all$values
#> [1] FALSE TRUE
#>
#> $mrt.all$unit_type
#> [1] "time"
#>
#> $mrt.all$pretty_name
#> [1] "MRT (based on AUCall)"
#>
#> $mrt.all$desc
#> [1] "MRT, AUCall/AUMCall"
#>
#> $mrt.all$sparse
#> [1] FALSE
#>
#> $mrt.all$formalsmap
#> $mrt.all$formalsmap$auc
#> [1] "aucall"
#>
#> $mrt.all$formalsmap$aumc
#> [1] "aumcall"
#>
#>
#> $mrt.all$depends
#> [1] "aucall" "aumcall"
#>
#> $mrt.all$datatype
#> [1] "interval"
#>
#> $mrt.all$pptestcd_cdisc
#> [1] "mrt.all"
#>
#> $mrt.all$pptest_cdisc
#> [1] "MRT, AUCall/AUMCall"
#>
#>
#> $mrt.int.all
#> $mrt.int.all$FUN
#> [1] "pk.calc.mrt"
#>
#> $mrt.int.all$values
#> [1] FALSE TRUE
#>
#> $mrt.int.all$unit_type
#> [1] "time"
#>
#> $mrt.int.all$pretty_name
#> [1] "MRT (based on AUCint.all)"
#>
#> $mrt.int.all$desc
#> [1] "MRT, interval AUCall/AUMCall"
#>
#> $mrt.int.all$sparse
#> [1] FALSE
#>
#> $mrt.int.all$formalsmap
#> $mrt.int.all$formalsmap$auc
#> [1] "aucint.all"
#>
#> $mrt.int.all$formalsmap$aumc
#> [1] "aumcint.all"
#>
#>
#> $mrt.int.all$depends
#> [1] "aucint.all" "aumcint.all"
#>
#> $mrt.int.all$datatype
#> [1] "interval"
#>
#> $mrt.int.all$pptestcd_cdisc
#> [1] "mrt.int.all"
#>
#> $mrt.int.all$pptest_cdisc
#> [1] "MRT, interval AUCall/AUMCall"
#>
#>
#> $mrt.int.last
#> $mrt.int.last$FUN
#> [1] "pk.calc.mrt"
#>
#> $mrt.int.last$values
#> [1] FALSE TRUE
#>
#> $mrt.int.last$unit_type
#> [1] "time"
#>
#> $mrt.int.last$pretty_name
#> [1] "MRT (based on AUCint.last)"
#>
#> $mrt.int.last$desc
#> [1] "MRT, interval AUClast/AUMClast"
#>
#> $mrt.int.last$sparse
#> [1] FALSE
#>
#> $mrt.int.last$formalsmap
#> $mrt.int.last$formalsmap$auc
#> [1] "aucint.last"
#>
#> $mrt.int.last$formalsmap$aumc
#> [1] "aumcint.last"
#>
#>
#> $mrt.int.last$depends
#> [1] "aucint.last" "aumcint.last"
#>
#> $mrt.int.last$datatype
#> [1] "interval"
#>
#> $mrt.int.last$pptestcd_cdisc
#> [1] "mrt.int.last"
#>
#> $mrt.int.last$pptest_cdisc
#> [1] "MRT, interval AUClast/AUMClast"
#>
#>
#> $mrt.iv.last
#> $mrt.iv.last$FUN
#> [1] "pk.calc.mrt.iv"
#>
#> $mrt.iv.last$values
#> [1] FALSE TRUE
#>
#> $mrt.iv.last$unit_type
#> [1] "time"
#>
#> $mrt.iv.last$pretty_name
#> [1] "MRT (for IV dosing, based on AUClast)"
#>
#> $mrt.iv.last$desc
#> [1] "IV MRT, AUClast/AUMClast"
#>
#> $mrt.iv.last$sparse
#> [1] FALSE
#>
#> $mrt.iv.last$formalsmap
#> $mrt.iv.last$formalsmap$auc
#> [1] "auclast"
#>
#> $mrt.iv.last$formalsmap$aumc
#> [1] "aumclast"
#>
#>
#> $mrt.iv.last$depends
#> [1] "auclast" "aumclast"
#>
#> $mrt.iv.last$datatype
#> [1] "interval"
#>
#> $mrt.iv.last$pptestcd_cdisc
#> [1] "MRTIBLST"
#>
#> $mrt.iv.last$pptest_cdisc
#> [1] "MRT Intravasc to Last Nonzero Conc"
#>
#>
#> $vss.last
#> $vss.last$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.last$values
#> [1] FALSE TRUE
#>
#> $vss.last$unit_type
#> [1] "volume"
#>
#> $vss.last$pretty_name
#> [1] "Vss (based on AUClast)"
#>
#> $vss.last$desc
#> [1] "Vss, calc'd through Tlast"
#>
#> $vss.last$sparse
#> [1] FALSE
#>
#> $vss.last$formalsmap
#> $vss.last$formalsmap$cl
#> [1] "cl.last"
#>
#> $vss.last$formalsmap$mrt
#> [1] "mrt.last"
#>
#>
#> $vss.last$depends
#> [1] "cl.last" "mrt.last"
#>
#> $vss.last$datatype
#> [1] "interval"
#>
#> $vss.last$pptestcd_cdisc
#> $vss.last$pptestcd_cdisc$route
#> $vss.last$pptestcd_cdisc$route$extravascular
#> [1] "VSSF/FLST"
#>
#> $vss.last$pptestcd_cdisc$route$intravascular
#> [1] "VSSLST"
#>
#>
#>
#> $vss.last$pptest_cdisc
#> $vss.last$pptest_cdisc$route
#> $vss.last$pptest_cdisc$route$extravascular
#> [1] "Vss by F (based on AUClast)"
#>
#> $vss.last$pptest_cdisc$route$intravascular
#> [1] "Vss (based on AUClast)"
#>
#>
#>
#>
#> $vss.iv.last
#> $vss.iv.last$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.iv.last$values
#> [1] FALSE TRUE
#>
#> $vss.iv.last$unit_type
#> [1] "volume"
#>
#> $vss.iv.last$pretty_name
#> [1] "Vss (for IV dosing, based on AUClast)"
#>
#> $vss.iv.last$desc
#> [1] "IV Vss, calc from AUClast"
#>
#> $vss.iv.last$sparse
#> [1] FALSE
#>
#> $vss.iv.last$formalsmap
#> $vss.iv.last$formalsmap$cl
#> [1] "cl.last"
#>
#> $vss.iv.last$formalsmap$mrt
#> [1] "mrt.iv.last"
#>
#>
#> $vss.iv.last$depends
#> [1] "cl.last" "mrt.iv.last"
#>
#> $vss.iv.last$datatype
#> [1] "interval"
#>
#> $vss.iv.last$pptestcd_cdisc
#> [1] "VSSIVLST"
#>
#> $vss.iv.last$pptest_cdisc
#> [1] "Vss (for IV dosing, based on AUClast)"
#>
#>
#> $vss.all
#> $vss.all$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.all$values
#> [1] FALSE TRUE
#>
#> $vss.all$unit_type
#> [1] "volume"
#>
#> $vss.all$pretty_name
#> [1] "Vss (based on AUCall)"
#>
#> $vss.all$desc
#> [1] "Vss, calc from AUCall"
#>
#> $vss.all$sparse
#> [1] FALSE
#>
#> $vss.all$formalsmap
#> $vss.all$formalsmap$cl
#> [1] "cl.all"
#>
#> $vss.all$formalsmap$mrt
#> [1] "mrt.all"
#>
#>
#> $vss.all$depends
#> [1] "cl.all" "mrt.all"
#>
#> $vss.all$datatype
#> [1] "interval"
#>
#> $vss.all$pptestcd_cdisc
#> [1] "vss.all"
#>
#> $vss.all$pptest_cdisc
#> [1] "Vss, calc from AUCall"
#>
#>
#> $vss.int.all
#> $vss.int.all$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.int.all$values
#> [1] FALSE TRUE
#>
#> $vss.int.all$unit_type
#> [1] "volume"
#>
#> $vss.int.all$pretty_name
#> [1] "Vss (based on AUCint.all)"
#>
#> $vss.int.all$desc
#> [1] "Vss, calc from interval AUCint.all"
#>
#> $vss.int.all$sparse
#> [1] FALSE
#>
#> $vss.int.all$formalsmap
#> $vss.int.all$formalsmap$cl
#> [1] "cl.int.all"
#>
#> $vss.int.all$formalsmap$mrt
#> [1] "mrt.int.all"
#>
#>
#> $vss.int.all$depends
#> [1] "cl.int.all" "mrt.int.all"
#>
#> $vss.int.all$datatype
#> [1] "interval"
#>
#> $vss.int.all$pptestcd_cdisc
#> [1] "vss.int.all"
#>
#> $vss.int.all$pptest_cdisc
#> [1] "Vss, calc from interval AUCint.all"
#>
#>
#> $vss.int.last
#> $vss.int.last$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.int.last$values
#> [1] FALSE TRUE
#>
#> $vss.int.last$unit_type
#> [1] "volume"
#>
#> $vss.int.last$pretty_name
#> [1] "Vss (based on AUCint.last)"
#>
#> $vss.int.last$desc
#> [1] "Vss, calc from interval AUCint.last"
#>
#> $vss.int.last$sparse
#> [1] FALSE
#>
#> $vss.int.last$formalsmap
#> $vss.int.last$formalsmap$cl
#> [1] "cl.int.last"
#>
#> $vss.int.last$formalsmap$mrt
#> [1] "mrt.int.last"
#>
#>
#> $vss.int.last$depends
#> [1] "cl.int.last" "mrt.int.last"
#>
#> $vss.int.last$datatype
#> [1] "interval"
#>
#> $vss.int.last$pptestcd_cdisc
#> [1] "vss.int.last"
#>
#> $vss.int.last$pptest_cdisc
#> [1] "Vss, calc from interval AUCint.last"
#>
#>
#> $cav
#> $cav$FUN
#> [1] "pk.calc.cav"
#>
#> $cav$values
#> [1] FALSE TRUE
#>
#> $cav$unit_type
#> [1] "conc"
#>
#> $cav$pretty_name
#> [1] "Cav"
#>
#> $cav$desc
#> [1] "Avg conc in interval (AUClast)"
#>
#> $cav$sparse
#> [1] FALSE
#>
#> $cav$formalsmap
#> $cav$formalsmap$auc
#> [1] "auclast"
#>
#>
#> $cav$depends
#> [1] "auclast"
#>
#> $cav$datatype
#> [1] "interval"
#>
#> $cav$pptestcd_cdisc
#> [1] "CAVG"
#>
#> $cav$pptest_cdisc
#> [1] "Average Conc"
#>
#>
#> $cav.int.last
#> $cav.int.last$FUN
#> [1] "pk.calc.cav"
#>
#> $cav.int.last$values
#> [1] FALSE TRUE
#>
#> $cav.int.last$unit_type
#> [1] "conc"
#>
#> $cav.int.last$pretty_name
#> [1] "Cav"
#>
#> $cav.int.last$desc
#> [1] "Avg conc in interval (AUCint.last)"
#>
#> $cav.int.last$sparse
#> [1] FALSE
#>
#> $cav.int.last$formalsmap
#> $cav.int.last$formalsmap$auc
#> [1] "aucint.last"
#>
#>
#> $cav.int.last$depends
#> [1] "aucint.last"
#>
#> $cav.int.last$datatype
#> [1] "interval"
#>
#> $cav.int.last$pptestcd_cdisc
#> [1] "CAVGINT"
#>
#> $cav.int.last$pptest_cdisc
#> [1] "Average Conc from T1 to T2"
#>
#>
#> $cav.int.all
#> $cav.int.all$FUN
#> [1] "pk.calc.cav"
#>
#> $cav.int.all$values
#> [1] FALSE TRUE
#>
#> $cav.int.all$unit_type
#> [1] "conc"
#>
#> $cav.int.all$pretty_name
#> [1] "Cav"
#>
#> $cav.int.all$desc
#> [1] "Avg conc in interval (AUCint.all)"
#>
#> $cav.int.all$sparse
#> [1] FALSE
#>
#> $cav.int.all$formalsmap
#> $cav.int.all$formalsmap$auc
#> [1] "aucint.all"
#>
#>
#> $cav.int.all$depends
#> [1] "aucint.all"
#>
#> $cav.int.all$datatype
#> [1] "interval"
#>
#> $cav.int.all$pptestcd_cdisc
#> [1] "CAVGINA"
#>
#> $cav.int.all$pptest_cdisc
#> [1] "Cavg All"
#>
#>
#> $ctrough
#> $ctrough$FUN
#> [1] "pk.calc.ctrough"
#>
#> $ctrough$values
#> [1] FALSE TRUE
#>
#> $ctrough$unit_type
#> [1] "conc"
#>
#> $ctrough$pretty_name
#> [1] "Ctrough"
#>
#> $ctrough$desc
#> [1] "Trough (end of interval) conc"
#>
#> $ctrough$sparse
#> [1] FALSE
#>
#> $ctrough$formalsmap
#> list()
#>
#> $ctrough$depends
#> NULL
#>
#> $ctrough$datatype
#> [1] "interval"
#>
#> $ctrough$pptestcd_cdisc
#> [1] "CTROUGH"
#>
#> $ctrough$pptest_cdisc
#> [1] "Conc Trough"
#>
#>
#> $cstart
#> $cstart$FUN
#> [1] "pk.calc.cstart"
#>
#> $cstart$values
#> [1] FALSE TRUE
#>
#> $cstart$unit_type
#> [1] "conc"
#>
#> $cstart$pretty_name
#> [1] "Cstart"
#>
#> $cstart$desc
#> [1] "The predose concentration"
#>
#> $cstart$sparse
#> [1] FALSE
#>
#> $cstart$formalsmap
#> list()
#>
#> $cstart$depends
#> NULL
#>
#> $cstart$datatype
#> [1] "interval"
#>
#> $cstart$pptestcd_cdisc
#> [1] "CSTART"
#>
#> $cstart$pptest_cdisc
#> [1] "Cstart"
#>
#>
#> $ptr
#> $ptr$FUN
#> [1] "pk.calc.ptr"
#>
#> $ptr$values
#> [1] FALSE TRUE
#>
#> $ptr$unit_type
#> [1] "fraction"
#>
#> $ptr$pretty_name
#> [1] "Peak-to-trough ratio"
#>
#> $ptr$desc
#> [1] "Peak-to-trough ratio"
#>
#> $ptr$sparse
#> [1] FALSE
#>
#> $ptr$formalsmap
#> list()
#>
#> $ptr$depends
#> [1] "cmax" "ctrough"
#>
#> $ptr$datatype
#> [1] "interval"
#>
#> $ptr$pptestcd_cdisc
#> [1] "PTROUGHR"
#>
#> $ptr$pptest_cdisc
#> [1] "Peak Trough Ratio"
#>
#>
#> $tlag
#> $tlag$FUN
#> [1] "pk.calc.tlag"
#>
#> $tlag$values
#> [1] FALSE TRUE
#>
#> $tlag$unit_type
#> [1] "time"
#>
#> $tlag$pretty_name
#> [1] "Tlag"
#>
#> $tlag$desc
#> [1] "Lag time"
#>
#> $tlag$sparse
#> [1] FALSE
#>
#> $tlag$formalsmap
#> list()
#>
#> $tlag$depends
#> NULL
#>
#> $tlag$datatype
#> [1] "interval"
#>
#> $tlag$pptestcd_cdisc
#> [1] "TLAG"
#>
#> $tlag$pptest_cdisc
#> [1] "Time to First Nonzero Conc"
#>
#>
#> $deg.fluc
#> $deg.fluc$FUN
#> [1] "pk.calc.deg.fluc"
#>
#> $deg.fluc$values
#> [1] FALSE TRUE
#>
#> $deg.fluc$unit_type
#> [1] "%"
#>
#> $deg.fluc$pretty_name
#> [1] "Degree of fluctuation"
#>
#> $deg.fluc$desc
#> [1] "Degree of fluctuation"
#>
#> $deg.fluc$sparse
#> [1] FALSE
#>
#> $deg.fluc$formalsmap
#> list()
#>
#> $deg.fluc$depends
#> [1] "cmax" "cmin" "cav"
#>
#> $deg.fluc$datatype
#> [1] "interval"
#>
#> $deg.fluc$pptestcd_cdisc
#> [1] "DEGFLUC"
#>
#> $deg.fluc$pptest_cdisc
#> [1] "Degree of fluctuation"
#>
#>
#> $swing
#> $swing$FUN
#> [1] "pk.calc.swing"
#>
#> $swing$values
#> [1] FALSE TRUE
#>
#> $swing$unit_type
#> [1] "%"
#>
#> $swing$pretty_name
#> [1] "Swing"
#>
#> $swing$desc
#> [1] "Swing relative to Cmin"
#>
#> $swing$sparse
#> [1] FALSE
#>
#> $swing$formalsmap
#> list()
#>
#> $swing$depends
#> [1] "cmax" "cmin"
#>
#> $swing$datatype
#> [1] "interval"
#>
#> $swing$pptestcd_cdisc
#> [1] "SWING"
#>
#> $swing$pptest_cdisc
#> [1] "Swing"
#>
#>
#> $ceoi
#> $ceoi$FUN
#> [1] "pk.calc.ceoi"
#>
#> $ceoi$values
#> [1] FALSE TRUE
#>
#> $ceoi$unit_type
#> [1] "conc"
#>
#> $ceoi$pretty_name
#> [1] "Ceoi"
#>
#> $ceoi$desc
#> [1] "Concentration at the end of infusion"
#>
#> $ceoi$sparse
#> [1] FALSE
#>
#> $ceoi$formalsmap
#> list()
#>
#> $ceoi$depends
#> NULL
#>
#> $ceoi$datatype
#> [1] "interval"
#>
#> $ceoi$pptestcd_cdisc
#> [1] "CEOI"
#>
#> $ceoi$pptest_cdisc
#> [1] "Ceoi"
#>
#>
#> $aucabove.predose.all
#> $aucabove.predose.all$FUN
#> [1] "pk.calc.aucabove"
#>
#> $aucabove.predose.all$values
#> [1] FALSE TRUE
#>
#> $aucabove.predose.all$unit_type
#> [1] "auc"
#>
#> $aucabove.predose.all$pretty_name
#> [1] "AUC,above"
#>
#> $aucabove.predose.all$desc
#> [1] "AUC above predose, floor at 0"
#>
#> $aucabove.predose.all$sparse
#> [1] FALSE
#>
#> $aucabove.predose.all$formalsmap
#> $aucabove.predose.all$formalsmap$conc_above
#> [1] "cstart"
#>
#>
#> $aucabove.predose.all$depends
#> [1] "cstart"
#>
#> $aucabove.predose.all$datatype
#> [1] "interval"
#>
#> $aucabove.predose.all$pptestcd_cdisc
#> [1] "AUCABVPA"
#>
#> $aucabove.predose.all$pptest_cdisc
#> [1] "AUC above predose"
#>
#>
#> $aucabove.trough.all
#> $aucabove.trough.all$FUN
#> [1] "pk.calc.aucabove"
#>
#> $aucabove.trough.all$values
#> [1] FALSE TRUE
#>
#> $aucabove.trough.all$unit_type
#> [1] "auc"
#>
#> $aucabove.trough.all$pretty_name
#> [1] "AUC,above"
#>
#> $aucabove.trough.all$desc
#> [1] "AUC above trough, floor at 0"
#>
#> $aucabove.trough.all$sparse
#> [1] FALSE
#>
#> $aucabove.trough.all$formalsmap
#> $aucabove.trough.all$formalsmap$conc_above
#> [1] "ctrough"
#>
#>
#> $aucabove.trough.all$depends
#> [1] "ctrough"
#>
#> $aucabove.trough.all$datatype
#> [1] "interval"
#>
#> $aucabove.trough.all$pptestcd_cdisc
#> [1] "AUCABVTA"
#>
#> $aucabove.trough.all$pptest_cdisc
#> [1] "AUC above trough"
#>
#>
#> $count_conc
#> $count_conc$FUN
#> [1] "pk.calc.count_conc"
#>
#> $count_conc$values
#> [1] FALSE TRUE
#>
#> $count_conc$unit_type
#> [1] "count"
#>
#> $count_conc$pretty_name
#> [1] "Concentration count"
#>
#> $count_conc$desc
#> [1] "Count of non-missing conc"
#>
#> $count_conc$sparse
#> [1] FALSE
#>
#> $count_conc$formalsmap
#> list()
#>
#> $count_conc$depends
#> NULL
#>
#> $count_conc$datatype
#> [1] "interval"
#>
#> $count_conc$pptestcd_cdisc
#> [1] "CNTCONC"
#>
#> $count_conc$pptest_cdisc
#> [1] "Concentration count"
#>
#>
#> $count_conc_measured
#> $count_conc_measured$FUN
#> [1] "pk.calc.count_conc_measured"
#>
#> $count_conc_measured$values
#> [1] FALSE TRUE
#>
#> $count_conc_measured$unit_type
#> [1] "count"
#>
#> $count_conc_measured$pretty_name
#> [1] "Measured concentration count"
#>
#> $count_conc_measured$desc
#> [1] "Count of measured, non-BLQ conc"
#>
#> $count_conc_measured$sparse
#> [1] FALSE
#>
#> $count_conc_measured$formalsmap
#> list()
#>
#> $count_conc_measured$depends
#> NULL
#>
#> $count_conc_measured$datatype
#> [1] "interval"
#>
#> $count_conc_measured$pptestcd_cdisc
#> [1] "count_conc_measured"
#>
#> $count_conc_measured$pptest_cdisc
#> [1] "Count of measured, non-BLQ conc"
#>
#>
#> $totdose
#> $totdose$FUN
#> [1] "pk.calc.totdose"
#>
#> $totdose$values
#> [1] FALSE TRUE
#>
#> $totdose$unit_type
#> [1] "dose"
#>
#> $totdose$pretty_name
#> [1] "Total dose"
#>
#> $totdose$desc
#> [1] "Total dose given in interval"
#>
#> $totdose$sparse
#> [1] FALSE
#>
#> $totdose$formalsmap
#> list()
#>
#> $totdose$depends
#> NULL
#>
#> $totdose$datatype
#> [1] "interval"
#>
#> $totdose$pptestcd_cdisc
#> [1] "TDOSE"
#>
#> $totdose$pptest_cdisc
#> [1] "Total dose administered"
#>
#>
#> $volpk
#> $volpk$FUN
#> [1] "pk.calc.volpk"
#>
#> $volpk$values
#> [1] FALSE TRUE
#>
#> $volpk$unit_type
#> [1] "volume"
#>
#> $volpk$pretty_name
#> [1] "Total Urine Volume"
#>
#> $volpk$desc
#> [1] "Sum of urine volumes for interval"
#>
#> $volpk$sparse
#> [1] FALSE
#>
#> $volpk$formalsmap
#> list()
#>
#> $volpk$depends
#> NULL
#>
#> $volpk$datatype
#> [1] "interval"
#>
#> $volpk$pptestcd_cdisc
#> [1] "VOLPK"
#>
#> $volpk$pptest_cdisc
#> [1] "Volume of PK sample"
#>
#>
#> $ae
#> $ae$FUN
#> [1] "pk.calc.ae"
#>
#> $ae$values
#> [1] FALSE TRUE
#>
#> $ae$unit_type
#> [1] "amount"
#>
#> $ae$pretty_name
#> [1] "Amount excreted"
#>
#> $ae$desc
#> [1] "Amount excreted (urine/feces)"
#>
#> $ae$sparse
#> [1] FALSE
#>
#> $ae$formalsmap
#> list()
#>
#> $ae$depends
#> NULL
#>
#> $ae$datatype
#> [1] "interval"
#>
#> $ae$pptestcd_cdisc
#> [1] "RCAMINT"
#>
#> $ae$pptest_cdisc
#> [1] "Amt Rec from T1 to T2"
#>
#>
#> $clr.last
#> $clr.last$FUN
#> [1] "pk.calc.clr"
#>
#> $clr.last$values
#> [1] FALSE TRUE
#>
#> $clr.last$unit_type
#> [1] "renal_clearance"
#>
#> $clr.last$pretty_name
#> [1] "Renal clearance (from AUClast)"
#>
#> $clr.last$desc
#> [1] "Renal clearance, AUClast"
#>
#> $clr.last$sparse
#> [1] FALSE
#>
#> $clr.last$formalsmap
#> $clr.last$formalsmap$auc
#> [1] "auclast"
#>
#>
#> $clr.last$depends
#> [1] "ae"
#>
#> $clr.last$datatype
#> [1] "interval"
#>
#> $clr.last$pptestcd_cdisc
#> [1] "RENALCL"
#>
#> $clr.last$pptest_cdisc
#> [1] "Renal CL"
#>
#>
#> $clr.obs
#> $clr.obs$FUN
#> [1] "pk.calc.clr"
#>
#> $clr.obs$values
#> [1] FALSE TRUE
#>
#> $clr.obs$unit_type
#> [1] "renal_clearance"
#>
#> $clr.obs$pretty_name
#> [1] "Renal clearance (from AUCinf,obs)"
#>
#> $clr.obs$desc
#> [1] "Renal clearance, AUCinf,obs"
#>
#> $clr.obs$sparse
#> [1] FALSE
#>
#> $clr.obs$formalsmap
#> $clr.obs$formalsmap$auc
#> [1] "aucinf.obs"
#>
#>
#> $clr.obs$depends
#> [1] "ae"
#>
#> $clr.obs$datatype
#> [1] "interval"
#>
#> $clr.obs$pptestcd_cdisc
#> [1] "RENALCL"
#>
#> $clr.obs$pptest_cdisc
#> [1] "Renal CL"
#>
#>
#> $clr.pred
#> $clr.pred$FUN
#> [1] "pk.calc.clr"
#>
#> $clr.pred$values
#> [1] FALSE TRUE
#>
#> $clr.pred$unit_type
#> [1] "renal_clearance"
#>
#> $clr.pred$pretty_name
#> [1] "Renal clearance (from AUCinf,pred)"
#>
#> $clr.pred$desc
#> [1] "Renal clearance, AUCinf,pred"
#>
#> $clr.pred$sparse
#> [1] FALSE
#>
#> $clr.pred$formalsmap
#> $clr.pred$formalsmap$auc
#> [1] "aucinf.pred"
#>
#>
#> $clr.pred$depends
#> [1] "ae"
#>
#> $clr.pred$datatype
#> [1] "interval"
#>
#> $clr.pred$pptestcd_cdisc
#> [1] "RENALCL"
#>
#> $clr.pred$pptest_cdisc
#> [1] "Renal CL"
#>
#>
#> $fe
#> $fe$FUN
#> [1] "pk.calc.fe"
#>
#> $fe$values
#> [1] FALSE TRUE
#>
#> $fe$unit_type
#> [1] "amount_dose"
#>
#> $fe$pretty_name
#> [1] "Fraction excreted"
#>
#> $fe$desc
#> [1] "Fraction of dose excreted"
#>
#> $fe$sparse
#> [1] FALSE
#>
#> $fe$formalsmap
#> list()
#>
#> $fe$depends
#> [1] "ae"
#>
#> $fe$datatype
#> [1] "interval"
#>
#> $fe$pptestcd_cdisc
#> [1] "FREXINT"
#>
#> $fe$pptest_cdisc
#> [1] "Fract Excr from T1 to T2"
#>
#>
#> $ertlst
#> $ertlst$FUN
#> [1] "pk.calc.ertlst"
#>
#> $ertlst$values
#> [1] FALSE TRUE
#>
#> $ertlst$unit_type
#> [1] "time"
#>
#> $ertlst$pretty_name
#> [1] "Tlast excretion rate"
#>
#> $ertlst$desc
#> [1] "Midpoint time of last excr rate"
#>
#> $ertlst$sparse
#> [1] FALSE
#>
#> $ertlst$formalsmap
#> list()
#>
#> $ertlst$depends
#> NULL
#>
#> $ertlst$datatype
#> [1] "interval"
#>
#> $ertlst$pptestcd_cdisc
#> [1] "ERTLST"
#>
#> $ertlst$pptest_cdisc
#> [1] "Time of Last Excretion Rate"
#>
#>
#> $ermax
#> $ermax$FUN
#> [1] "pk.calc.ermax"
#>
#> $ermax$values
#> [1] FALSE TRUE
#>
#> $ermax$unit_type
#> [1] "amount_time"
#>
#> $ermax$pretty_name
#> [1] "Maximum excretion rate"
#>
#> $ermax$desc
#> [1] "Maximum excretion rate"
#>
#> $ermax$sparse
#> [1] FALSE
#>
#> $ermax$formalsmap
#> list()
#>
#> $ermax$depends
#> NULL
#>
#> $ermax$datatype
#> [1] "interval"
#>
#> $ermax$pptestcd_cdisc
#> [1] "ERMAX"
#>
#> $ermax$pptest_cdisc
#> [1] "Max Excretion Rate"
#>
#>
#> $ertmax
#> $ertmax$FUN
#> [1] "pk.calc.ertmax"
#>
#> $ertmax$values
#> [1] FALSE TRUE
#>
#> $ertmax$unit_type
#> [1] "time"
#>
#> $ertmax$pretty_name
#> [1] "Tmax excretion rate"
#>
#> $ertmax$desc
#> [1] "Midpoint time of max excr rate"
#>
#> $ertmax$sparse
#> [1] FALSE
#>
#> $ertmax$formalsmap
#> list()
#>
#> $ertmax$depends
#> NULL
#>
#> $ertmax$datatype
#> [1] "interval"
#>
#> $ertmax$pptestcd_cdisc
#> [1] "ERTMAX"
#>
#> $ertmax$pptest_cdisc
#> [1] "Midpoint of Interval of Maximum ER"
#>
#>
#> $sparse_auclast
#> $sparse_auclast$FUN
#> [1] "pk.calc.sparse_auclast"
#>
#> $sparse_auclast$values
#> [1] FALSE TRUE
#>
#> $sparse_auclast$unit_type
#> [1] "auc"
#>
#> $sparse_auclast$pretty_name
#> [1] "Sparse AUClast"
#>
#> $sparse_auclast$desc
#> [1] "Sparse AUC to last conc above LOQ"
#>
#> $sparse_auclast$sparse
#> [1] TRUE
#>
#> $sparse_auclast$formalsmap
#> list()
#>
#> $sparse_auclast$depends
#> NULL
#>
#> $sparse_auclast$datatype
#> [1] "interval"
#>
#> $sparse_auclast$pptestcd_cdisc
#> [1] "SPARSEAL"
#>
#> $sparse_auclast$pptest_cdisc
#> [1] "Sparse AUClast"
#>
#>
#> $sparse_auc_se
#> $sparse_auc_se$FUN
#> [1] NA
#>
#> $sparse_auc_se$values
#> [1] FALSE TRUE
#>
#> $sparse_auc_se$unit_type
#> [1] "auc"
#>
#> $sparse_auc_se$pretty_name
#> [1] "Sparse AUClast standard error"
#>
#> $sparse_auc_se$desc
#> [1] "SE of sparse AUC to last conc above LOQ"
#>
#> $sparse_auc_se$sparse
#> [1] FALSE
#>
#> $sparse_auc_se$formalsmap
#> list()
#>
#> $sparse_auc_se$depends
#> [1] "sparse_auclast"
#>
#> $sparse_auc_se$datatype
#> [1] "interval"
#>
#> $sparse_auc_se$pptestcd_cdisc
#> [1] "SPARSEAS"
#>
#> $sparse_auc_se$pptest_cdisc
#> [1] "Sparse AUClast standard error"
#>
#>
#> $sparse_auc_df
#> $sparse_auc_df$FUN
#> [1] NA
#>
#> $sparse_auc_df$values
#> [1] FALSE TRUE
#>
#> $sparse_auc_df$unit_type
#> [1] "count"
#>
#> $sparse_auc_df$pretty_name
#> [1] "Sparse AUClast degrees of freedom"
#>
#> $sparse_auc_df$desc
#> [1] "DF for sparse AUC to last conc above LOQ"
#>
#> $sparse_auc_df$sparse
#> [1] FALSE
#>
#> $sparse_auc_df$formalsmap
#> list()
#>
#> $sparse_auc_df$depends
#> [1] "sparse_auclast"
#>
#> $sparse_auc_df$datatype
#> [1] "interval"
#>
#> $sparse_auc_df$pptestcd_cdisc
#> [1] "SPARSEAD"
#>
#> $sparse_auc_df$pptest_cdisc
#> [1] "Sparse AUClast degrees of freedom"
#>
#>
#> $sparse_aumclast
#> $sparse_aumclast$FUN
#> [1] "pk.calc.sparse_aumclast"
#>
#> $sparse_aumclast$values
#> [1] FALSE TRUE
#>
#> $sparse_aumclast$unit_type
#> [1] "aumc"
#>
#> $sparse_aumclast$pretty_name
#> [1] "Sparse AUMClast"
#>
#> $sparse_aumclast$desc
#> [1] "Sparse AUMC to last conc above LOQ"
#>
#> $sparse_aumclast$sparse
#> [1] TRUE
#>
#> $sparse_aumclast$formalsmap
#> list()
#>
#> $sparse_aumclast$depends
#> [1] "sparse_auclast"
#>
#> $sparse_aumclast$datatype
#> [1] "interval"
#>
#> $sparse_aumclast$pptestcd_cdisc
#> [1] "sparse_aumclast"
#>
#> $sparse_aumclast$pptest_cdisc
#> [1] "Sparse AUMC to last conc above LOQ"
#>
#>
#> $sparse_aumc_se
#> $sparse_aumc_se$FUN
#> [1] NA
#>
#> $sparse_aumc_se$values
#> [1] FALSE TRUE
#>
#> $sparse_aumc_se$unit_type
#> [1] "aumc"
#>
#> $sparse_aumc_se$pretty_name
#> [1] "Sparse AUMC standard error"
#>
#> $sparse_aumc_se$desc
#> [1] "SE of sparse AUMC to last conc above LOQ"
#>
#> $sparse_aumc_se$sparse
#> [1] FALSE
#>
#> $sparse_aumc_se$formalsmap
#> list()
#>
#> $sparse_aumc_se$depends
#> [1] "sparse_aumclast"
#>
#> $sparse_aumc_se$datatype
#> [1] "interval"
#>
#> $sparse_aumc_se$pptestcd_cdisc
#> [1] "sparse_aumc_se"
#>
#> $sparse_aumc_se$pptest_cdisc
#> [1] "SE of sparse AUMC to last conc above LOQ"
#>
#>
#> $sparse_aumc_df
#> $sparse_aumc_df$FUN
#> [1] NA
#>
#> $sparse_aumc_df$values
#> [1] FALSE TRUE
#>
#> $sparse_aumc_df$unit_type
#> [1] "count"
#>
#> $sparse_aumc_df$pretty_name
#> [1] "Sparse AUMC degrees of freedom"
#>
#> $sparse_aumc_df$desc
#> [1] "variance DF for sparse AUMC to Tlast"
#>
#> $sparse_aumc_df$sparse
#> [1] FALSE
#>
#> $sparse_aumc_df$formalsmap
#> list()
#>
#> $sparse_aumc_df$depends
#> [1] "sparse_aumclast"
#>
#> $sparse_aumc_df$datatype
#> [1] "interval"
#>
#> $sparse_aumc_df$pptestcd_cdisc
#> [1] "sparse_aumc_df"
#>
#> $sparse_aumc_df$pptest_cdisc
#> [1] "variance DF for sparse AUMC to Tlast"
#>
#>
#> $time_above
#> $time_above$FUN
#> [1] "pk.calc.time_above"
#>
#> $time_above$values
#> [1] FALSE TRUE
#>
#> $time_above$unit_type
#> [1] "time"
#>
#> $time_above$pretty_name
#> [1] "Time above Concentration"
#>
#> $time_above$desc
#> [1] "Time above a given concentration"
#>
#> $time_above$sparse
#> [1] FALSE
#>
#> $time_above$formalsmap
#> list()
#>
#> $time_above$depends
#> NULL
#>
#> $time_above$datatype
#> [1] "interval"
#>
#> $time_above$pptestcd_cdisc
#> [1] "TAT"
#>
#> $time_above$pptest_cdisc
#> [1] "Time Above Threshold"
#>
#>
#> $aucivlast
#> $aucivlast$FUN
#> [1] "pk.calc.auciv"
#>
#> $aucivlast$values
#> [1] FALSE TRUE
#>
#> $aucivlast$unit_type
#> [1] "auc"
#>
#> $aucivlast$pretty_name
#> [1] "AUClast (IV dosing)"
#>
#> $aucivlast$desc
#> [1] "AUClast, IV back-extrap C0"
#>
#> $aucivlast$sparse
#> [1] FALSE
#>
#> $aucivlast$formalsmap
#> $aucivlast$formalsmap$auc
#> [1] "auclast"
#>
#>
#> $aucivlast$depends
#> [1] "auclast" "c0"
#>
#> $aucivlast$datatype
#> [1] "interval"
#>
#> $aucivlast$pptestcd_cdisc
#> [1] "AUCIVLST"
#>
#> $aucivlast$pptest_cdisc
#> [1] "AUClast (IV dosing)"
#>
#>
#> $aucivall
#> $aucivall$FUN
#> [1] "pk.calc.auciv"
#>
#> $aucivall$values
#> [1] FALSE TRUE
#>
#> $aucivall$unit_type
#> [1] "auc"
#>
#> $aucivall$pretty_name
#> [1] "AUCall (IV dosing)"
#>
#> $aucivall$desc
#> [1] "AUCall, IV back-extrap C0"
#>
#> $aucivall$sparse
#> [1] FALSE
#>
#> $aucivall$formalsmap
#> $aucivall$formalsmap$auc
#> [1] "aucall"
#>
#>
#> $aucivall$depends
#> [1] "aucall" "c0"
#>
#> $aucivall$datatype
#> [1] "interval"
#>
#> $aucivall$pptestcd_cdisc
#> [1] "AUCIVA"
#>
#> $aucivall$pptest_cdisc
#> [1] "AUCall (IV dosing)"
#>
#>
#> $aucivint.last
#> $aucivint.last$FUN
#> [1] "pk.calc.auciv"
#>
#> $aucivint.last$values
#> [1] FALSE TRUE
#>
#> $aucivint.last$unit_type
#> [1] "auc"
#>
#> $aucivint.last$pretty_name
#> [1] "AUCint,last (IV dosing)"
#>
#> $aucivint.last$desc
#> [1] "AUCint.last, IV back-extrap C0"
#>
#> $aucivint.last$sparse
#> [1] FALSE
#>
#> $aucivint.last$formalsmap
#> $aucivint.last$formalsmap$auc
#> [1] "aucint.last"
#>
#>
#> $aucivint.last$depends
#> [1] "aucint.last" "c0"
#>
#> $aucivint.last$datatype
#> [1] "interval"
#>
#> $aucivint.last$pptestcd_cdisc
#> [1] "AUCIVILT"
#>
#> $aucivint.last$pptest_cdisc
#> [1] "AUCint,last (IV dosing)"
#>
#>
#> $aucivint.all
#> $aucivint.all$FUN
#> [1] "pk.calc.auciv"
#>
#> $aucivint.all$values
#> [1] FALSE TRUE
#>
#> $aucivint.all$unit_type
#> [1] "auc"
#>
#> $aucivint.all$pretty_name
#> [1] "AUCint,all (IV dosing)"
#>
#> $aucivint.all$desc
#> [1] "AUCint.all, IV back-extrap C0"
#>
#> $aucivint.all$sparse
#> [1] FALSE
#>
#> $aucivint.all$formalsmap
#> $aucivint.all$formalsmap$auc
#> [1] "aucint.all"
#>
#>
#> $aucivint.all$depends
#> [1] "aucint.all" "c0"
#>
#> $aucivint.all$datatype
#> [1] "interval"
#>
#> $aucivint.all$pptestcd_cdisc
#> [1] "AUCIVINA"
#>
#> $aucivint.all$pptest_cdisc
#> [1] "AUCint,all (IV dosing)"
#>
#>
#> $aucivpbextlast
#> $aucivpbextlast$FUN
#> [1] "pk.calc.auciv_pbext"
#>
#> $aucivpbextlast$values
#> [1] FALSE TRUE
#>
#> $aucivpbextlast$unit_type
#> [1] "%"
#>
#> $aucivpbextlast$pretty_name
#> [1] "AUCbext (based on AUClast)"
#>
#> $aucivpbextlast$desc
#> [1] "Back-extrap %, IV, AUClast"
#>
#> $aucivpbextlast$sparse
#> [1] FALSE
#>
#> $aucivpbextlast$formalsmap
#> $aucivpbextlast$formalsmap$auc
#> [1] "auclast"
#>
#> $aucivpbextlast$formalsmap$auciv
#> [1] "aucivlast"
#>
#>
#> $aucivpbextlast$depends
#> [1] "auclast" "aucivlast"
#>
#> $aucivpbextlast$datatype
#> [1] "interval"
#>
#> $aucivpbextlast$pptestcd_cdisc
#> [1] "AUCIVPLT"
#>
#> $aucivpbextlast$pptest_cdisc
#> [1] "AUCbext (based on AUClast)"
#>
#>
#> $aucivpbextall
#> $aucivpbextall$FUN
#> [1] "pk.calc.auciv_pbext"
#>
#> $aucivpbextall$values
#> [1] FALSE TRUE
#>
#> $aucivpbextall$unit_type
#> [1] "%"
#>
#> $aucivpbextall$pretty_name
#> [1] "AUCbext (based on AUCall)"
#>
#> $aucivpbextall$desc
#> [1] "Back-extrap %, IV, AUCall"
#>
#> $aucivpbextall$sparse
#> [1] FALSE
#>
#> $aucivpbextall$formalsmap
#> $aucivpbextall$formalsmap$auc
#> [1] "aucall"
#>
#> $aucivpbextall$formalsmap$auciv
#> [1] "aucivall"
#>
#>
#> $aucivpbextall$depends
#> [1] "aucall" "aucivall"
#>
#> $aucivpbextall$datatype
#> [1] "interval"
#>
#> $aucivpbextall$pptestcd_cdisc
#> [1] "AUCIVPEA"
#>
#> $aucivpbextall$pptest_cdisc
#> [1] "AUCbext (based on AUCall)"
#>
#>
#> $aucivpbextint.last
#> $aucivpbextint.last$FUN
#> [1] "pk.calc.auciv_pbext"
#>
#> $aucivpbextint.last$values
#> [1] FALSE TRUE
#>
#> $aucivpbextint.last$unit_type
#> [1] "%"
#>
#> $aucivpbextint.last$pretty_name
#> [1] "AUCbext (based on AUCint,last)"
#>
#> $aucivpbextint.last$desc
#> [1] "Back-extrap %, IV, AUCint.last"
#>
#> $aucivpbextint.last$sparse
#> [1] FALSE
#>
#> $aucivpbextint.last$formalsmap
#> $aucivpbextint.last$formalsmap$auc
#> [1] "aucint.last"
#>
#> $aucivpbextint.last$formalsmap$auciv
#> [1] "aucivint.last"
#>
#>
#> $aucivpbextint.last$depends
#> [1] "aucint.last" "aucivint.last"
#>
#> $aucivpbextint.last$datatype
#> [1] "interval"
#>
#> $aucivpbextint.last$pptestcd_cdisc
#> [1] "AUCIVPIL"
#>
#> $aucivpbextint.last$pptest_cdisc
#> [1] "AUCbext (based on AUCint,last)"
#>
#>
#> $aucivpbextint.all
#> $aucivpbextint.all$FUN
#> [1] "pk.calc.auciv_pbext"
#>
#> $aucivpbextint.all$values
#> [1] FALSE TRUE
#>
#> $aucivpbextint.all$unit_type
#> [1] "%"
#>
#> $aucivpbextint.all$pretty_name
#> [1] "AUCbext (based on AUCint,all)"
#>
#> $aucivpbextint.all$desc
#> [1] "Back-extrap %, IV, AUCint.all"
#>
#> $aucivpbextint.all$sparse
#> [1] FALSE
#>
#> $aucivpbextint.all$formalsmap
#> $aucivpbextint.all$formalsmap$auc
#> [1] "aucint.all"
#>
#> $aucivpbextint.all$formalsmap$auciv
#> [1] "aucivint.all"
#>
#>
#> $aucivpbextint.all$depends
#> [1] "aucint.all" "aucivint.all"
#>
#> $aucivpbextint.all$datatype
#> [1] "interval"
#>
#> $aucivpbextint.all$pptestcd_cdisc
#> [1] "AUCIVPIA"
#>
#> $aucivpbextint.all$pptest_cdisc
#> [1] "AUCbext (based on AUCint,all)"
#>
#>
#> $aumcivlast
#> $aumcivlast$FUN
#> [1] "pk.calc.aumciv"
#>
#> $aumcivlast$values
#> [1] FALSE TRUE
#>
#> $aumcivlast$unit_type
#> [1] "aumc"
#>
#> $aumcivlast$pretty_name
#> [1] "AUMClast (IV dosing)"
#>
#> $aumcivlast$desc
#> [1] "AUMClast, IV back-extrap C0"
#>
#> $aumcivlast$sparse
#> [1] FALSE
#>
#> $aumcivlast$formalsmap
#> $aumcivlast$formalsmap$aumc
#> [1] "aumclast"
#>
#>
#> $aumcivlast$depends
#> [1] "aumclast" "c0"
#>
#> $aumcivlast$datatype
#> [1] "interval"
#>
#> $aumcivlast$pptestcd_cdisc
#> [1] "aumcivlast"
#>
#> $aumcivlast$pptest_cdisc
#> [1] "AUMClast, IV back-extrap C0"
#>
#>
#> $aumcivall
#> $aumcivall$FUN
#> [1] "pk.calc.aumciv"
#>
#> $aumcivall$values
#> [1] FALSE TRUE
#>
#> $aumcivall$unit_type
#> [1] "aumc"
#>
#> $aumcivall$pretty_name
#> [1] "AUMCall (IV dosing)"
#>
#> $aumcivall$desc
#> [1] "AUMCall, IV back-extrap C0"
#>
#> $aumcivall$sparse
#> [1] FALSE
#>
#> $aumcivall$formalsmap
#> $aumcivall$formalsmap$aumc
#> [1] "aumcall"
#>
#>
#> $aumcivall$depends
#> [1] "aumcall" "c0"
#>
#> $aumcivall$datatype
#> [1] "interval"
#>
#> $aumcivall$pptestcd_cdisc
#> [1] "aumcivall"
#>
#> $aumcivall$pptest_cdisc
#> [1] "AUMCall, IV back-extrap C0"
#>
#>
#> $aumcivint.last
#> $aumcivint.last$FUN
#> [1] "pk.calc.aumciv"
#>
#> $aumcivint.last$values
#> [1] FALSE TRUE
#>
#> $aumcivint.last$unit_type
#> [1] "aumc"
#>
#> $aumcivint.last$pretty_name
#> [1] "AUMCint,last (IV dosing)"
#>
#> $aumcivint.last$desc
#> [1] "AUMCint.last, IV back-extrap C0"
#>
#> $aumcivint.last$sparse
#> [1] FALSE
#>
#> $aumcivint.last$formalsmap
#> $aumcivint.last$formalsmap$aumc
#> [1] "aumcint.last"
#>
#>
#> $aumcivint.last$depends
#> [1] "aumcint.last" "c0"
#>
#> $aumcivint.last$datatype
#> [1] "interval"
#>
#> $aumcivint.last$pptestcd_cdisc
#> [1] "aumcivint.last"
#>
#> $aumcivint.last$pptest_cdisc
#> [1] "AUMCint.last, IV back-extrap C0"
#>
#>
#> $aumcivint.all
#> $aumcivint.all$FUN
#> [1] "pk.calc.aumciv"
#>
#> $aumcivint.all$values
#> [1] FALSE TRUE
#>
#> $aumcivint.all$unit_type
#> [1] "aumc"
#>
#> $aumcivint.all$pretty_name
#> [1] "AUMCint,all (IV dosing)"
#>
#> $aumcivint.all$desc
#> [1] "AUMCint.all, IV back-extrap C0"
#>
#> $aumcivint.all$sparse
#> [1] FALSE
#>
#> $aumcivint.all$formalsmap
#> $aumcivint.all$formalsmap$aumc
#> [1] "aumcint.all"
#>
#>
#> $aumcivint.all$depends
#> [1] "aumcint.all" "c0"
#>
#> $aumcivint.all$datatype
#> [1] "interval"
#>
#> $aumcivint.all$pptestcd_cdisc
#> [1] "aumcivint.all"
#>
#> $aumcivint.all$pptest_cdisc
#> [1] "AUMCint.all, IV back-extrap C0"
#>
#>
#> $half.life
#> $half.life$FUN
#> [1] "pk.calc.half.life"
#>
#> $half.life$values
#> [1] FALSE TRUE
#>
#> $half.life$unit_type
#> [1] "time"
#>
#> $half.life$pretty_name
#> [1] "Half-life"
#>
#> $half.life$desc
#> [1] "The (terminal) half-life"
#>
#> $half.life$sparse
#> [1] FALSE
#>
#> $half.life$formalsmap
#> list()
#>
#> $half.life$depends
#> [1] "tmax" "tlast"
#>
#> $half.life$datatype
#> [1] "interval"
#>
#> $half.life$pptestcd_cdisc
#> [1] "LAMZHL"
#>
#> $half.life$pptest_cdisc
#> [1] "Half-Life Lambda z"
#>
#>
#> $r.squared
#> $r.squared$FUN
#> [1] NA
#>
#> $r.squared$values
#> [1] FALSE TRUE
#>
#> $r.squared$unit_type
#> [1] "unitless"
#>
#> $r.squared$pretty_name
#> [1] "$r^2$"
#>
#> $r.squared$desc
#> [1] "R-squared of half-life fit"
#>
#> $r.squared$sparse
#> [1] FALSE
#>
#> $r.squared$formalsmap
#> list()
#>
#> $r.squared$depends
#> [1] "half.life"
#>
#> $r.squared$datatype
#> [1] "interval"
#>
#> $r.squared$pptestcd_cdisc
#> [1] "R2"
#>
#> $r.squared$pptest_cdisc
#> [1] "R Squared"
#>
#>
#> $adj.r.squared
#> $adj.r.squared$FUN
#> [1] NA
#>
#> $adj.r.squared$values
#> [1] FALSE TRUE
#>
#> $adj.r.squared$unit_type
#> [1] "unitless"
#>
#> $adj.r.squared$pretty_name
#> [1] "$r^2_{adj}$"
#>
#> $adj.r.squared$desc
#> [1] "Adjusted R-sq of half-life fit"
#>
#> $adj.r.squared$sparse
#> [1] FALSE
#>
#> $adj.r.squared$formalsmap
#> list()
#>
#> $adj.r.squared$depends
#> [1] "half.life"
#>
#> $adj.r.squared$datatype
#> [1] "interval"
#>
#> $adj.r.squared$pptestcd_cdisc
#> [1] "R2ADJ"
#>
#> $adj.r.squared$pptest_cdisc
#> [1] "R Squared Adjusted"
#>
#>
#> $lambda.z.corrxy
#> $lambda.z.corrxy$FUN
#> [1] NA
#>
#> $lambda.z.corrxy$values
#> [1] FALSE TRUE
#>
#> $lambda.z.corrxy$unit_type
#> [1] "unitless"
#>
#> $lambda.z.corrxy$pretty_name
#> [1] "Correlation (time, log-conc)"
#>
#> $lambda.z.corrxy$desc
#> [1] "Corr(time,log-conc) for lambda.z"
#>
#> $lambda.z.corrxy$sparse
#> [1] FALSE
#>
#> $lambda.z.corrxy$formalsmap
#> list()
#>
#> $lambda.z.corrxy$depends
#> [1] "half.life"
#>
#> $lambda.z.corrxy$datatype
#> [1] "interval"
#>
#> $lambda.z.corrxy$pptestcd_cdisc
#> [1] "CORRXY"
#>
#> $lambda.z.corrxy$pptest_cdisc
#> [1] "Correlation Between TimeX and Log ConcY"
#>
#>
#> $lambda.z
#> $lambda.z$FUN
#> [1] NA
#>
#> $lambda.z$values
#> [1] FALSE TRUE
#>
#> $lambda.z$unit_type
#> [1] "inverse_time"
#>
#> $lambda.z$pretty_name
#> [1] "$\\lambda_z$"
#>
#> $lambda.z$desc
#> [1] "Terminal elim rate (lambda.z)"
#>
#> $lambda.z$sparse
#> [1] FALSE
#>
#> $lambda.z$formalsmap
#> list()
#>
#> $lambda.z$depends
#> [1] "half.life"
#>
#> $lambda.z$datatype
#> [1] "interval"
#>
#> $lambda.z$pptestcd_cdisc
#> [1] "LAMZ"
#>
#> $lambda.z$pptest_cdisc
#> [1] "Lambda z"
#>
#>
#> $lambda.z.time.first
#> $lambda.z.time.first$FUN
#> [1] NA
#>
#> $lambda.z.time.first$values
#> [1] FALSE TRUE
#>
#> $lambda.z.time.first$unit_type
#> [1] "time"
#>
#> $lambda.z.time.first$pretty_name
#> [1] "First time for $\\lambda_z$"
#>
#> $lambda.z.time.first$desc
#> [1] "First time point for lambda.z"
#>
#> $lambda.z.time.first$sparse
#> [1] FALSE
#>
#> $lambda.z.time.first$formalsmap
#> list()
#>
#> $lambda.z.time.first$depends
#> [1] "half.life"
#>
#> $lambda.z.time.first$datatype
#> [1] "interval"
#>
#> $lambda.z.time.first$pptestcd_cdisc
#> [1] "LAMZLL"
#>
#> $lambda.z.time.first$pptest_cdisc
#> [1] "Lambda z Lower Limit"
#>
#>
#> $lambda.z.time.last
#> $lambda.z.time.last$FUN
#> [1] NA
#>
#> $lambda.z.time.last$values
#> [1] FALSE TRUE
#>
#> $lambda.z.time.last$unit_type
#> [1] "time"
#>
#> $lambda.z.time.last$pretty_name
#> [1] "Last time for $\\lambda_z$"
#>
#> $lambda.z.time.last$desc
#> [1] "Last time point for lambda.z"
#>
#> $lambda.z.time.last$sparse
#> [1] FALSE
#>
#> $lambda.z.time.last$formalsmap
#> list()
#>
#> $lambda.z.time.last$depends
#> [1] "half.life"
#>
#> $lambda.z.time.last$datatype
#> [1] "interval"
#>
#> $lambda.z.time.last$pptestcd_cdisc
#> [1] "LAMZUL"
#>
#> $lambda.z.time.last$pptest_cdisc
#> [1] "Lambda z Upper Limit"
#>
#>
#> $lambda.z.n.points
#> $lambda.z.n.points$FUN
#> [1] NA
#>
#> $lambda.z.n.points$values
#> [1] FALSE TRUE
#>
#> $lambda.z.n.points$unit_type
#> [1] "count"
#>
#> $lambda.z.n.points$pretty_name
#> [1] "Number of points used for lambda_z"
#>
#> $lambda.z.n.points$desc
#> [1] "Number of points used, lambda.z"
#>
#> $lambda.z.n.points$sparse
#> [1] FALSE
#>
#> $lambda.z.n.points$formalsmap
#> list()
#>
#> $lambda.z.n.points$depends
#> [1] "half.life"
#>
#> $lambda.z.n.points$datatype
#> [1] "interval"
#>
#> $lambda.z.n.points$pptestcd_cdisc
#> [1] "LAMZNPT"
#>
#> $lambda.z.n.points$pptest_cdisc
#> [1] "Number of Points for Lambda z"
#>
#>
#> $clast.pred
#> $clast.pred$FUN
#> [1] NA
#>
#> $clast.pred$values
#> [1] FALSE TRUE
#>
#> $clast.pred$unit_type
#> [1] "conc"
#>
#> $clast.pred$pretty_name
#> [1] "Clast,pred"
#>
#> $clast.pred$desc
#> [1] "Predicted Clast from half-life"
#>
#> $clast.pred$sparse
#> [1] FALSE
#>
#> $clast.pred$formalsmap
#> list()
#>
#> $clast.pred$depends
#> [1] "half.life"
#>
#> $clast.pred$datatype
#> [1] "interval"
#>
#> $clast.pred$pptestcd_cdisc
#> [1] "CLSTP"
#>
#> $clast.pred$pptest_cdisc
#> [1] "Clast pred"
#>
#>
#> $span.ratio
#> $span.ratio$FUN
#> [1] NA
#>
#> $span.ratio$values
#> [1] FALSE TRUE
#>
#> $span.ratio$unit_type
#> [1] "fraction"
#>
#> $span.ratio$pretty_name
#> [1] "Span ratio"
#>
#> $span.ratio$desc
#> [1] "Lambda z time span to half-life ratio"
#>
#> $span.ratio$sparse
#> [1] FALSE
#>
#> $span.ratio$formalsmap
#> list()
#>
#> $span.ratio$depends
#> [1] "half.life"
#>
#> $span.ratio$datatype
#> [1] "interval"
#>
#> $span.ratio$pptestcd_cdisc
#> [1] "LAMZSPN"
#>
#> $span.ratio$pptest_cdisc
#> [1] "Lambda z Span"
#>
#>
#> $tobit_residual
#> $tobit_residual$FUN
#> [1] NA
#>
#> $tobit_residual$values
#> [1] FALSE TRUE
#>
#> $tobit_residual$unit_type
#> [1] "unitless"
#>
#> $tobit_residual$pretty_name
#> [1] "Tobit residual SD"
#>
#> $tobit_residual$desc
#> [1] "Tobit fit residual SD, log-conc"
#>
#> $tobit_residual$sparse
#> [1] FALSE
#>
#> $tobit_residual$formalsmap
#> list()
#>
#> $tobit_residual$depends
#> [1] "half.life"
#>
#> $tobit_residual$datatype
#> [1] "interval"
#>
#> $tobit_residual$pptestcd_cdisc
#> [1] "tobit_residual"
#>
#> $tobit_residual$pptest_cdisc
#> [1] "Tobit fit residual SD, log-conc"
#>
#>
#> $adj_tobit_residual
#> $adj_tobit_residual$FUN
#> [1] NA
#>
#> $adj_tobit_residual$values
#> [1] FALSE TRUE
#>
#> $adj_tobit_residual$unit_type
#> [1] "unitless"
#>
#> $adj_tobit_residual$pretty_name
#> [1] "Adjusted Tobit residual SD"
#>
#> $adj_tobit_residual$desc
#> [1] "Adjusted Tobit residual SD"
#>
#> $adj_tobit_residual$sparse
#> [1] FALSE
#>
#> $adj_tobit_residual$formalsmap
#> list()
#>
#> $adj_tobit_residual$depends
#> [1] "half.life"
#>
#> $adj_tobit_residual$datatype
#> [1] "interval"
#>
#> $adj_tobit_residual$pptestcd_cdisc
#> [1] "adj_tobit_residual"
#>
#> $adj_tobit_residual$pptest_cdisc
#> [1] "Adjusted Tobit residual SD"
#>
#>
#> $lambda.z.n.points_blq
#> $lambda.z.n.points_blq$FUN
#> [1] NA
#>
#> $lambda.z.n.points_blq$values
#> [1] FALSE TRUE
#>
#> $lambda.z.n.points_blq$unit_type
#> [1] "count"
#>
#> $lambda.z.n.points_blq$pretty_name
#> [1] "Number of BLQ points for lambda_z (Tobit)"
#>
#> $lambda.z.n.points_blq$desc
#> [1] "BLQ points in Tobit lambda.z"
#>
#> $lambda.z.n.points_blq$sparse
#> [1] FALSE
#>
#> $lambda.z.n.points_blq$formalsmap
#> list()
#>
#> $lambda.z.n.points_blq$depends
#> [1] "half.life"
#>
#> $lambda.z.n.points_blq$datatype
#> [1] "interval"
#>
#> $lambda.z.n.points_blq$pptestcd_cdisc
#> [1] "lambda.z.n.points_blq"
#>
#> $lambda.z.n.points_blq$pptest_cdisc
#> [1] "BLQ points in Tobit lambda.z"
#>
#>
#> $thalf.eff.last
#> $thalf.eff.last$FUN
#> [1] "pk.calc.thalf.eff"
#>
#> $thalf.eff.last$values
#> [1] FALSE TRUE
#>
#> $thalf.eff.last$unit_type
#> [1] "time"
#>
#> $thalf.eff.last$pretty_name
#> [1] "Effective half-life (based on MRT,last)"
#>
#> $thalf.eff.last$desc
#> [1] "Effective half-life, MRTlast"
#>
#> $thalf.eff.last$sparse
#> [1] FALSE
#>
#> $thalf.eff.last$formalsmap
#> $thalf.eff.last$formalsmap$mrt
#> [1] "mrt.last"
#>
#>
#> $thalf.eff.last$depends
#> [1] "mrt.last"
#>
#> $thalf.eff.last$datatype
#> [1] "interval"
#>
#> $thalf.eff.last$pptestcd_cdisc
#> [1] "EFFHL"
#>
#> $thalf.eff.last$pptest_cdisc
#> [1] "Effective Half-Life (based on AUClast)"
#>
#>
#> $thalf.eff.iv.last
#> $thalf.eff.iv.last$FUN
#> [1] "pk.calc.thalf.eff"
#>
#> $thalf.eff.iv.last$values
#> [1] FALSE TRUE
#>
#> $thalf.eff.iv.last$unit_type
#> [1] "time"
#>
#> $thalf.eff.iv.last$pretty_name
#> [1] "Effective half-life (for IV dosing, based on MRTlast)"
#>
#> $thalf.eff.iv.last$desc
#> [1] "Effective half-life, IV MRTlast"
#>
#> $thalf.eff.iv.last$sparse
#> [1] FALSE
#>
#> $thalf.eff.iv.last$formalsmap
#> $thalf.eff.iv.last$formalsmap$mrt
#> [1] "mrt.iv.last"
#>
#>
#> $thalf.eff.iv.last$depends
#> [1] "mrt.iv.last"
#>
#> $thalf.eff.iv.last$datatype
#> [1] "interval"
#>
#> $thalf.eff.iv.last$pptestcd_cdisc
#> [1] "EFFIVLHL"
#>
#> $thalf.eff.iv.last$pptest_cdisc
#> [1] "Effective Half-Life (for IV dosing, based on AUClast)"
#>
#>
#> $kel.last
#> $kel.last$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.last$values
#> [1] FALSE TRUE
#>
#> $kel.last$unit_type
#> [1] "inverse_time"
#>
#> $kel.last$pretty_name
#> [1] "Kel (based on AUClast)"
#>
#> $kel.last$desc
#> [1] "Elim rate, MRT via AUClast"
#>
#> $kel.last$sparse
#> [1] FALSE
#>
#> $kel.last$formalsmap
#> $kel.last$formalsmap$mrt
#> [1] "mrt.last"
#>
#>
#> $kel.last$depends
#> [1] "mrt.last"
#>
#> $kel.last$datatype
#> [1] "interval"
#>
#> $kel.last$pptestcd_cdisc
#> [1] "KELLST"
#>
#> $kel.last$pptest_cdisc
#> [1] "Kel (based on AUClast)"
#>
#>
#> $kel.iv.last
#> $kel.iv.last$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.iv.last$values
#> [1] FALSE TRUE
#>
#> $kel.iv.last$unit_type
#> [1] "inverse_time"
#>
#> $kel.iv.last$pretty_name
#> [1] "Kel (for IV dosing, based on AUClast)"
#>
#> $kel.iv.last$desc
#> [1] "Elim rate, IV MRTlast"
#>
#> $kel.iv.last$sparse
#> [1] FALSE
#>
#> $kel.iv.last$formalsmap
#> $kel.iv.last$formalsmap$mrt
#> [1] "mrt.iv.last"
#>
#>
#> $kel.iv.last$depends
#> [1] "mrt.iv.last"
#>
#> $kel.iv.last$datatype
#> [1] "interval"
#>
#> $kel.iv.last$pptestcd_cdisc
#> [1] "KELIVLT"
#>
#> $kel.iv.last$pptest_cdisc
#> [1] "Kel (for IV dosing, based on AUClast)"
#>
#>
#> $kel.all
#> $kel.all$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.all$values
#> [1] FALSE TRUE
#>
#> $kel.all$unit_type
#> [1] "inverse_time"
#>
#> $kel.all$pretty_name
#> [1] "Kel (based on AUCall)"
#>
#> $kel.all$desc
#> [1] "Elim rate, MRTall"
#>
#> $kel.all$sparse
#> [1] FALSE
#>
#> $kel.all$formalsmap
#> $kel.all$formalsmap$mrt
#> [1] "mrt.all"
#>
#>
#> $kel.all$depends
#> [1] "mrt.all"
#>
#> $kel.all$datatype
#> [1] "interval"
#>
#> $kel.all$pptestcd_cdisc
#> [1] "kel.all"
#>
#> $kel.all$pptest_cdisc
#> [1] "Elim rate, MRTall"
#>
#>
#> $kel.int.all
#> $kel.int.all$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.int.all$values
#> [1] FALSE TRUE
#>
#> $kel.int.all$unit_type
#> [1] "inverse_time"
#>
#> $kel.int.all$pretty_name
#> [1] "Kel (based on AUCint.all)"
#>
#> $kel.int.all$desc
#> [1] "Elim rate, MRTint.all"
#>
#> $kel.int.all$sparse
#> [1] FALSE
#>
#> $kel.int.all$formalsmap
#> $kel.int.all$formalsmap$mrt
#> [1] "mrt.int.all"
#>
#>
#> $kel.int.all$depends
#> [1] "mrt.int.all"
#>
#> $kel.int.all$datatype
#> [1] "interval"
#>
#> $kel.int.all$pptestcd_cdisc
#> [1] "kel.int.all"
#>
#> $kel.int.all$pptest_cdisc
#> [1] "Elim rate, MRTint.all"
#>
#>
#> $kel.int.last
#> $kel.int.last$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.int.last$values
#> [1] FALSE TRUE
#>
#> $kel.int.last$unit_type
#> [1] "inverse_time"
#>
#> $kel.int.last$pretty_name
#> [1] "Kel (based on AUCint.last)"
#>
#> $kel.int.last$desc
#> [1] "Elim rate, MRTint.last"
#>
#> $kel.int.last$sparse
#> [1] FALSE
#>
#> $kel.int.last$formalsmap
#> $kel.int.last$formalsmap$mrt
#> [1] "mrt.int.last"
#>
#>
#> $kel.int.last$depends
#> [1] "mrt.int.last"
#>
#> $kel.int.last$datatype
#> [1] "interval"
#>
#> $kel.int.last$pptestcd_cdisc
#> [1] "kel.int.last"
#>
#> $kel.int.last$pptest_cdisc
#> [1] "Elim rate, MRTint.last"
#>
#>
#> $cl.iv.all
#> $cl.iv.all$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.iv.all$values
#> [1] FALSE TRUE
#>
#> $cl.iv.all$unit_type
#> [1] "clearance"
#>
#> $cl.iv.all$pretty_name
#> [1] "CL (for IV dosing, based on AUCall)"
#>
#> $cl.iv.all$desc
#> [1] "IV clearance, AUCall"
#>
#> $cl.iv.all$sparse
#> [1] FALSE
#>
#> $cl.iv.all$formalsmap
#> $cl.iv.all$formalsmap$auc
#> [1] "aucivall"
#>
#>
#> $cl.iv.all$depends
#> [1] "aucivall"
#>
#> $cl.iv.all$datatype
#> [1] "interval"
#>
#> $cl.iv.all$pptestcd_cdisc
#> [1] "cl.iv.all"
#>
#> $cl.iv.all$pptest_cdisc
#> [1] "IV clearance, AUCall"
#>
#>
#> $cl.iv.last
#> $cl.iv.last$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.iv.last$values
#> [1] FALSE TRUE
#>
#> $cl.iv.last$unit_type
#> [1] "clearance"
#>
#> $cl.iv.last$pretty_name
#> [1] "CL (for IV dosing, based on AUClast)"
#>
#> $cl.iv.last$desc
#> [1] "IV clearance, AUClast"
#>
#> $cl.iv.last$sparse
#> [1] FALSE
#>
#> $cl.iv.last$formalsmap
#> $cl.iv.last$formalsmap$auc
#> [1] "aucivlast"
#>
#>
#> $cl.iv.last$depends
#> [1] "aucivlast"
#>
#> $cl.iv.last$datatype
#> [1] "interval"
#>
#> $cl.iv.last$pptestcd_cdisc
#> [1] "cl.iv.last"
#>
#> $cl.iv.last$pptest_cdisc
#> [1] "IV clearance, AUClast"
#>
#>
#> $cl.ivint.all
#> $cl.ivint.all$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.ivint.all$values
#> [1] FALSE TRUE
#>
#> $cl.ivint.all$unit_type
#> [1] "clearance"
#>
#> $cl.ivint.all$pretty_name
#> [1] "CL (IV dose interval, based on AUCint.all)"
#>
#> $cl.ivint.all$desc
#> [1] "IV clearance, AUCint.all"
#>
#> $cl.ivint.all$sparse
#> [1] FALSE
#>
#> $cl.ivint.all$formalsmap
#> $cl.ivint.all$formalsmap$auc
#> [1] "aucivint.all"
#>
#>
#> $cl.ivint.all$depends
#> [1] "aucivint.all"
#>
#> $cl.ivint.all$datatype
#> [1] "interval"
#>
#> $cl.ivint.all$pptestcd_cdisc
#> [1] "cl.ivint.all"
#>
#> $cl.ivint.all$pptest_cdisc
#> [1] "IV clearance, AUCint.all"
#>
#>
#> $cl.ivint.last
#> $cl.ivint.last$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.ivint.last$values
#> [1] FALSE TRUE
#>
#> $cl.ivint.last$unit_type
#> [1] "clearance"
#>
#> $cl.ivint.last$pretty_name
#> [1] "CL (IV dose interval, based on AUCint.last)"
#>
#> $cl.ivint.last$desc
#> [1] "IV clearance, AUCint.last"
#>
#> $cl.ivint.last$sparse
#> [1] FALSE
#>
#> $cl.ivint.last$formalsmap
#> $cl.ivint.last$formalsmap$auc
#> [1] "aucivint.last"
#>
#>
#> $cl.ivint.last$depends
#> [1] "aucivint.last"
#>
#> $cl.ivint.last$datatype
#> [1] "interval"
#>
#> $cl.ivint.last$pptestcd_cdisc
#> [1] "cl.ivint.last"
#>
#> $cl.ivint.last$pptest_cdisc
#> [1] "IV clearance, AUCint.last"
#>
#>
#> $cl.sparse.last
#> $cl.sparse.last$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.sparse.last$values
#> [1] FALSE TRUE
#>
#> $cl.sparse.last$unit_type
#> [1] "clearance"
#>
#> $cl.sparse.last$pretty_name
#> [1] "CL (for sparse data, based on AUClast)"
#>
#> $cl.sparse.last$desc
#> [1] "Clearance, sparse AUClast"
#>
#> $cl.sparse.last$sparse
#> [1] TRUE
#>
#> $cl.sparse.last$formalsmap
#> $cl.sparse.last$formalsmap$auc
#> [1] "sparse_auclast"
#>
#>
#> $cl.sparse.last$depends
#> [1] "sparse_auclast"
#>
#> $cl.sparse.last$datatype
#> [1] "interval"
#>
#> $cl.sparse.last$pptestcd_cdisc
#> [1] "cl.sparse.last"
#>
#> $cl.sparse.last$pptest_cdisc
#> [1] "Clearance, sparse AUClast"
#>
#>
#> $mrt.sparse.last
#> $mrt.sparse.last$FUN
#> [1] "pk.calc.mrt"
#>
#> $mrt.sparse.last$values
#> [1] FALSE TRUE
#>
#> $mrt.sparse.last$unit_type
#> [1] "time"
#>
#> $mrt.sparse.last$pretty_name
#> [1] "MRT (for sparse data, based on AUClast)"
#>
#> $mrt.sparse.last$desc
#> [1] "MRT, sparse AUClast/AUMClast"
#>
#> $mrt.sparse.last$sparse
#> [1] TRUE
#>
#> $mrt.sparse.last$formalsmap
#> $mrt.sparse.last$formalsmap$auc
#> [1] "sparse_auclast"
#>
#> $mrt.sparse.last$formalsmap$aumc
#> [1] "sparse_aumclast"
#>
#>
#> $mrt.sparse.last$depends
#> [1] "sparse_auclast" "sparse_aumclast"
#>
#> $mrt.sparse.last$datatype
#> [1] "interval"
#>
#> $mrt.sparse.last$pptestcd_cdisc
#> [1] "mrt.sparse.last"
#>
#> $mrt.sparse.last$pptest_cdisc
#> [1] "MRT, sparse AUClast/AUMClast"
#>
#>
#> $mrt.iv.all
#> $mrt.iv.all$FUN
#> [1] "pk.calc.mrt.iv"
#>
#> $mrt.iv.all$values
#> [1] FALSE TRUE
#>
#> $mrt.iv.all$unit_type
#> [1] "time"
#>
#> $mrt.iv.all$pretty_name
#> [1] "MRT (for IV dosing, based on AUCall)"
#>
#> $mrt.iv.all$desc
#> [1] "IV MRT, AUCall/AUMCall"
#>
#> $mrt.iv.all$sparse
#> [1] FALSE
#>
#> $mrt.iv.all$formalsmap
#> $mrt.iv.all$formalsmap$auc
#> [1] "aucivall"
#>
#> $mrt.iv.all$formalsmap$aumc
#> [1] "aumcivall"
#>
#>
#> $mrt.iv.all$depends
#> [1] "aucivall" "aumcivall"
#>
#> $mrt.iv.all$datatype
#> [1] "interval"
#>
#> $mrt.iv.all$pptestcd_cdisc
#> [1] "mrt.iv.all"
#>
#> $mrt.iv.all$pptest_cdisc
#> [1] "IV MRT, AUCall/AUMCall"
#>
#>
#> $mrt.ivint.all
#> $mrt.ivint.all$FUN
#> [1] "pk.calc.mrt.iv"
#>
#> $mrt.ivint.all$values
#> [1] FALSE TRUE
#>
#> $mrt.ivint.all$unit_type
#> [1] "time"
#>
#> $mrt.ivint.all$pretty_name
#> [1] "MRT (IV dose interval, based on AUCint.all)"
#>
#> $mrt.ivint.all$desc
#> [1] "IV MRT, interval AUC/AUMCall"
#>
#> $mrt.ivint.all$sparse
#> [1] FALSE
#>
#> $mrt.ivint.all$formalsmap
#> $mrt.ivint.all$formalsmap$auc
#> [1] "aucivint.all"
#>
#> $mrt.ivint.all$formalsmap$aumc
#> [1] "aumcivint.all"
#>
#>
#> $mrt.ivint.all$depends
#> [1] "aucivint.all" "aumcivint.all"
#>
#> $mrt.ivint.all$datatype
#> [1] "interval"
#>
#> $mrt.ivint.all$pptestcd_cdisc
#> [1] "mrt.ivint.all"
#>
#> $mrt.ivint.all$pptest_cdisc
#> [1] "IV MRT, interval AUC/AUMCall"
#>
#>
#> $mrt.ivint.last
#> $mrt.ivint.last$FUN
#> [1] "pk.calc.mrt.iv"
#>
#> $mrt.ivint.last$values
#> [1] FALSE TRUE
#>
#> $mrt.ivint.last$unit_type
#> [1] "time"
#>
#> $mrt.ivint.last$pretty_name
#> [1] "MRT (IV dose interval, based on AUCint.last)"
#>
#> $mrt.ivint.last$desc
#> [1] "IV MRT, interval AUC/AUMClast"
#>
#> $mrt.ivint.last$sparse
#> [1] FALSE
#>
#> $mrt.ivint.last$formalsmap
#> $mrt.ivint.last$formalsmap$auc
#> [1] "aucivint.last"
#>
#> $mrt.ivint.last$formalsmap$aumc
#> [1] "aumcivint.last"
#>
#>
#> $mrt.ivint.last$depends
#> [1] "aucivint.last" "aumcivint.last"
#>
#> $mrt.ivint.last$datatype
#> [1] "interval"
#>
#> $mrt.ivint.last$pptestcd_cdisc
#> [1] "mrt.ivint.last"
#>
#> $mrt.ivint.last$pptest_cdisc
#> [1] "IV MRT, interval AUC/AUMClast"
#>
#>
#> $vz.all
#> $vz.all$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.all$values
#> [1] FALSE TRUE
#>
#> $vz.all$unit_type
#> [1] "volume"
#>
#> $vz.all$pretty_name
#> [1] "Vz (based on AUCall)"
#>
#> $vz.all$desc
#> [1] "Vz, AUCall-based CL"
#>
#> $vz.all$sparse
#> [1] FALSE
#>
#> $vz.all$formalsmap
#> $vz.all$formalsmap$cl
#> [1] "cl.all"
#>
#>
#> $vz.all$depends
#> [1] "cl.all" "lambda.z"
#>
#> $vz.all$datatype
#> [1] "interval"
#>
#> $vz.all$pptestcd_cdisc
#> [1] "vz.all"
#>
#> $vz.all$pptest_cdisc
#> [1] "Vz, AUCall-based CL"
#>
#>
#> $vz.int.all
#> $vz.int.all$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.int.all$values
#> [1] FALSE TRUE
#>
#> $vz.int.all$unit_type
#> [1] "volume"
#>
#> $vz.int.all$pretty_name
#> [1] "Vz (based on AUCint.all)"
#>
#> $vz.int.all$desc
#> [1] "Vz, interval AUCint.all"
#>
#> $vz.int.all$sparse
#> [1] FALSE
#>
#> $vz.int.all$formalsmap
#> $vz.int.all$formalsmap$cl
#> [1] "cl.int.all"
#>
#>
#> $vz.int.all$depends
#> [1] "cl.int.all" "lambda.z"
#>
#> $vz.int.all$datatype
#> [1] "interval"
#>
#> $vz.int.all$pptestcd_cdisc
#> [1] "vz.int.all"
#>
#> $vz.int.all$pptest_cdisc
#> [1] "Vz, interval AUCint.all"
#>
#>
#> $vz.int.last
#> $vz.int.last$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.int.last$values
#> [1] FALSE TRUE
#>
#> $vz.int.last$unit_type
#> [1] "volume"
#>
#> $vz.int.last$pretty_name
#> [1] "Vz (based on AUCint.last)"
#>
#> $vz.int.last$desc
#> [1] "Vz, interval AUCint.last"
#>
#> $vz.int.last$sparse
#> [1] FALSE
#>
#> $vz.int.last$formalsmap
#> $vz.int.last$formalsmap$cl
#> [1] "cl.int.last"
#>
#>
#> $vz.int.last$depends
#> [1] "cl.int.last" "lambda.z"
#>
#> $vz.int.last$datatype
#> [1] "interval"
#>
#> $vz.int.last$pptestcd_cdisc
#> [1] "vz.int.last"
#>
#> $vz.int.last$pptest_cdisc
#> [1] "Vz, interval AUCint.last"
#>
#>
#> $vz.iv.all
#> $vz.iv.all$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.iv.all$values
#> [1] FALSE TRUE
#>
#> $vz.iv.all$unit_type
#> [1] "volume"
#>
#> $vz.iv.all$pretty_name
#> [1] "Vz (for IV dosing, based on AUCall)"
#>
#> $vz.iv.all$desc
#> [1] "IV Vz, AUCall"
#>
#> $vz.iv.all$sparse
#> [1] FALSE
#>
#> $vz.iv.all$formalsmap
#> $vz.iv.all$formalsmap$cl
#> [1] "cl.iv.all"
#>
#>
#> $vz.iv.all$depends
#> [1] "cl.iv.all" "lambda.z"
#>
#> $vz.iv.all$datatype
#> [1] "interval"
#>
#> $vz.iv.all$pptestcd_cdisc
#> [1] "vz.iv.all"
#>
#> $vz.iv.all$pptest_cdisc
#> [1] "IV Vz, AUCall"
#>
#>
#> $vz.iv.last
#> $vz.iv.last$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.iv.last$values
#> [1] FALSE TRUE
#>
#> $vz.iv.last$unit_type
#> [1] "volume"
#>
#> $vz.iv.last$pretty_name
#> [1] "Vz (for IV dosing, based on AUClast)"
#>
#> $vz.iv.last$desc
#> [1] "IV Vz, AUClast"
#>
#> $vz.iv.last$sparse
#> [1] FALSE
#>
#> $vz.iv.last$formalsmap
#> $vz.iv.last$formalsmap$cl
#> [1] "cl.iv.last"
#>
#>
#> $vz.iv.last$depends
#> [1] "cl.iv.last" "lambda.z"
#>
#> $vz.iv.last$datatype
#> [1] "interval"
#>
#> $vz.iv.last$pptestcd_cdisc
#> [1] "vz.iv.last"
#>
#> $vz.iv.last$pptest_cdisc
#> [1] "IV Vz, AUClast"
#>
#>
#> $vz.ivint.all
#> $vz.ivint.all$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.ivint.all$values
#> [1] FALSE TRUE
#>
#> $vz.ivint.all$unit_type
#> [1] "volume"
#>
#> $vz.ivint.all$pretty_name
#> [1] "Vz (IV dose interval, based on AUCint.all)"
#>
#> $vz.ivint.all$desc
#> [1] "IV Vz, interval AUCint.all"
#>
#> $vz.ivint.all$sparse
#> [1] FALSE
#>
#> $vz.ivint.all$formalsmap
#> $vz.ivint.all$formalsmap$cl
#> [1] "cl.ivint.all"
#>
#>
#> $vz.ivint.all$depends
#> [1] "cl.ivint.all" "lambda.z"
#>
#> $vz.ivint.all$datatype
#> [1] "interval"
#>
#> $vz.ivint.all$pptestcd_cdisc
#> [1] "vz.ivint.all"
#>
#> $vz.ivint.all$pptest_cdisc
#> [1] "IV Vz, interval AUCint.all"
#>
#>
#> $vz.ivint.last
#> $vz.ivint.last$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.ivint.last$values
#> [1] FALSE TRUE
#>
#> $vz.ivint.last$unit_type
#> [1] "volume"
#>
#> $vz.ivint.last$pretty_name
#> [1] "Vz (IV dose interval, based on AUCint.last)"
#>
#> $vz.ivint.last$desc
#> [1] "IV Vz, interval AUCint.last"
#>
#> $vz.ivint.last$sparse
#> [1] FALSE
#>
#> $vz.ivint.last$formalsmap
#> $vz.ivint.last$formalsmap$cl
#> [1] "cl.ivint.last"
#>
#>
#> $vz.ivint.last$depends
#> [1] "cl.ivint.last" "lambda.z"
#>
#> $vz.ivint.last$datatype
#> [1] "interval"
#>
#> $vz.ivint.last$pptestcd_cdisc
#> [1] "vz.ivint.last"
#>
#> $vz.ivint.last$pptest_cdisc
#> [1] "IV Vz, interval AUCint.last"
#>
#>
#> $vz.last
#> $vz.last$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.last$values
#> [1] FALSE TRUE
#>
#> $vz.last$unit_type
#> [1] "volume"
#>
#> $vz.last$pretty_name
#> [1] "Vz (based on AUClast)"
#>
#> $vz.last$desc
#> [1] "Vz, AUClast-based CL"
#>
#> $vz.last$sparse
#> [1] FALSE
#>
#> $vz.last$formalsmap
#> $vz.last$formalsmap$cl
#> [1] "cl.last"
#>
#>
#> $vz.last$depends
#> [1] "cl.last" "lambda.z"
#>
#> $vz.last$datatype
#> [1] "interval"
#>
#> $vz.last$pptestcd_cdisc
#> [1] "vz.last"
#>
#> $vz.last$pptest_cdisc
#> [1] "Vz, AUClast-based CL"
#>
#>
#> $vss.iv.all
#> $vss.iv.all$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.iv.all$values
#> [1] FALSE TRUE
#>
#> $vss.iv.all$unit_type
#> [1] "volume"
#>
#> $vss.iv.all$pretty_name
#> [1] "Vss (for IV dosing, based on AUCall)"
#>
#> $vss.iv.all$desc
#> [1] "IV Vss, calc from AUCall"
#>
#> $vss.iv.all$sparse
#> [1] FALSE
#>
#> $vss.iv.all$formalsmap
#> $vss.iv.all$formalsmap$cl
#> [1] "cl.iv.all"
#>
#> $vss.iv.all$formalsmap$mrt
#> [1] "mrt.iv.all"
#>
#>
#> $vss.iv.all$depends
#> [1] "cl.iv.all" "mrt.iv.all"
#>
#> $vss.iv.all$datatype
#> [1] "interval"
#>
#> $vss.iv.all$pptestcd_cdisc
#> [1] "vss.iv.all"
#>
#> $vss.iv.all$pptest_cdisc
#> [1] "IV Vss, calc from AUCall"
#>
#>
#> $vss.ivint.all
#> $vss.ivint.all$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.ivint.all$values
#> [1] FALSE TRUE
#>
#> $vss.ivint.all$unit_type
#> [1] "volume"
#>
#> $vss.ivint.all$pretty_name
#> [1] "Vss (IV dose interval, based on AUCint.all)"
#>
#> $vss.ivint.all$desc
#> [1] "IV Vss, calc from interval AUCint.all"
#>
#> $vss.ivint.all$sparse
#> [1] FALSE
#>
#> $vss.ivint.all$formalsmap
#> $vss.ivint.all$formalsmap$cl
#> [1] "cl.ivint.all"
#>
#> $vss.ivint.all$formalsmap$mrt
#> [1] "mrt.ivint.all"
#>
#>
#> $vss.ivint.all$depends
#> [1] "cl.ivint.all" "mrt.ivint.all"
#>
#> $vss.ivint.all$datatype
#> [1] "interval"
#>
#> $vss.ivint.all$pptestcd_cdisc
#> [1] "vss.ivint.all"
#>
#> $vss.ivint.all$pptest_cdisc
#> [1] "IV Vss, calc from interval AUCint.all"
#>
#>
#> $vss.ivint.last
#> $vss.ivint.last$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.ivint.last$values
#> [1] FALSE TRUE
#>
#> $vss.ivint.last$unit_type
#> [1] "volume"
#>
#> $vss.ivint.last$pretty_name
#> [1] "Vss (IV dose interval, based on AUCint.last)"
#>
#> $vss.ivint.last$desc
#> [1] "IV Vss, calc from interval AUCint.last"
#>
#> $vss.ivint.last$sparse
#> [1] FALSE
#>
#> $vss.ivint.last$formalsmap
#> $vss.ivint.last$formalsmap$cl
#> [1] "cl.ivint.last"
#>
#> $vss.ivint.last$formalsmap$mrt
#> [1] "mrt.ivint.last"
#>
#>
#> $vss.ivint.last$depends
#> [1] "cl.ivint.last" "mrt.ivint.last"
#>
#> $vss.ivint.last$datatype
#> [1] "interval"
#>
#> $vss.ivint.last$pptestcd_cdisc
#> [1] "vss.ivint.last"
#>
#> $vss.ivint.last$pptest_cdisc
#> [1] "IV Vss, calc from interval AUCint.last"
#>
#>
#> $vss.sparse.last
#> $vss.sparse.last$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.sparse.last$values
#> [1] FALSE TRUE
#>
#> $vss.sparse.last$unit_type
#> [1] "volume"
#>
#> $vss.sparse.last$pretty_name
#> [1] "Vss (for sparse data, based on AUClast)"
#>
#> $vss.sparse.last$desc
#> [1] "Vss, calc from sparse AUClast"
#>
#> $vss.sparse.last$sparse
#> [1] TRUE
#>
#> $vss.sparse.last$formalsmap
#> $vss.sparse.last$formalsmap$cl
#> [1] "cl.sparse.last"
#>
#> $vss.sparse.last$formalsmap$mrt
#> [1] "mrt.sparse.last"
#>
#>
#> $vss.sparse.last$depends
#> [1] "cl.sparse.last" "mrt.sparse.last"
#>
#> $vss.sparse.last$datatype
#> [1] "interval"
#>
#> $vss.sparse.last$pptestcd_cdisc
#> [1] "vss.sparse.last"
#>
#> $vss.sparse.last$pptest_cdisc
#> [1] "Vss, calc from sparse AUClast"
#>
#>
#> $aucinf.obs
#> $aucinf.obs$FUN
#> [1] "pk.calc.auc.inf.obs"
#>
#> $aucinf.obs$values
#> [1] FALSE TRUE
#>
#> $aucinf.obs$unit_type
#> [1] "auc"
#>
#> $aucinf.obs$pretty_name
#> [1] "AUCinf,obs"
#>
#> $aucinf.obs$desc
#> [1] "AUC start to inf, obs Clast extrap"
#>
#> $aucinf.obs$sparse
#> [1] FALSE
#>
#> $aucinf.obs$formalsmap
#> list()
#>
#> $aucinf.obs$depends
#> [1] "lambda.z" "clast.obs"
#>
#> $aucinf.obs$datatype
#> [1] "interval"
#>
#> $aucinf.obs$pptestcd_cdisc
#> [1] "AUCIFO"
#>
#> $aucinf.obs$pptest_cdisc
#> [1] "AUC Infinity Obs"
#>
#>
#> $aucinf.pred
#> $aucinf.pred$FUN
#> [1] "pk.calc.auc.inf.pred"
#>
#> $aucinf.pred$values
#> [1] FALSE TRUE
#>
#> $aucinf.pred$unit_type
#> [1] "auc"
#>
#> $aucinf.pred$pretty_name
#> [1] "AUCinf,pred"
#>
#> $aucinf.pred$desc
#> [1] "AUC start to inf, pred Clast extrap"
#>
#> $aucinf.pred$sparse
#> [1] FALSE
#>
#> $aucinf.pred$formalsmap
#> list()
#>
#> $aucinf.pred$depends
#> [1] "lambda.z" "clast.pred"
#>
#> $aucinf.pred$datatype
#> [1] "interval"
#>
#> $aucinf.pred$pptestcd_cdisc
#> [1] "AUCIFP"
#>
#> $aucinf.pred$pptest_cdisc
#> [1] "AUC Infinity Pred"
#>
#>
#> $aumcinf.obs
#> $aumcinf.obs$FUN
#> [1] "pk.calc.aumc.inf.obs"
#>
#> $aumcinf.obs$values
#> [1] FALSE TRUE
#>
#> $aumcinf.obs$unit_type
#> [1] "aumc"
#>
#> $aumcinf.obs$pretty_name
#> [1] "AUMC,inf,obs"
#>
#> $aumcinf.obs$desc
#> [1] "AUMC start to inf, obs Clast extrap"
#>
#> $aumcinf.obs$sparse
#> [1] FALSE
#>
#> $aumcinf.obs$formalsmap
#> list()
#>
#> $aumcinf.obs$depends
#> [1] "lambda.z" "clast.obs"
#>
#> $aumcinf.obs$datatype
#> [1] "interval"
#>
#> $aumcinf.obs$pptestcd_cdisc
#> [1] "AUMCIFO"
#>
#> $aumcinf.obs$pptest_cdisc
#> [1] "AUMC Infinity Obs"
#>
#>
#> $aumcinf.pred
#> $aumcinf.pred$FUN
#> [1] "pk.calc.aumc.inf.pred"
#>
#> $aumcinf.pred$values
#> [1] FALSE TRUE
#>
#> $aumcinf.pred$unit_type
#> [1] "aumc"
#>
#> $aumcinf.pred$pretty_name
#> [1] "AUMC,inf,pred"
#>
#> $aumcinf.pred$desc
#> [1] "AUMC start to inf, pred Clast extrap"
#>
#> $aumcinf.pred$sparse
#> [1] FALSE
#>
#> $aumcinf.pred$formalsmap
#> list()
#>
#> $aumcinf.pred$depends
#> [1] "lambda.z" "clast.pred"
#>
#> $aumcinf.pred$datatype
#> [1] "interval"
#>
#> $aumcinf.pred$pptestcd_cdisc
#> [1] "AUMCIFP"
#>
#> $aumcinf.pred$pptest_cdisc
#> [1] "AUMC Infinity Pred"
#>
#>
#> $aucint.inf.obs
#> $aucint.inf.obs$FUN
#> [1] "pk.calc.aucint.inf.obs"
#>
#> $aucint.inf.obs$values
#> [1] FALSE TRUE
#>
#> $aucint.inf.obs$unit_type
#> [1] "auc"
#>
#> $aucint.inf.obs$pretty_name
#> [1] "AUCint (based on AUCinf,obs extrapolation)"
#>
#> $aucint.inf.obs$desc
#> [1] "AUC from T1 to T2 (AUCinf,obs extrap)"
#>
#> $aucint.inf.obs$sparse
#> [1] FALSE
#>
#> $aucint.inf.obs$formalsmap
#> $aucint.inf.obs$formalsmap$conc
#> [1] "conc.group"
#>
#> $aucint.inf.obs$formalsmap$time
#> [1] "time.group"
#>
#> $aucint.inf.obs$formalsmap$time.dose
#> NULL
#>
#>
#> $aucint.inf.obs$depends
#> [1] "lambda.z" "clast.obs"
#>
#> $aucint.inf.obs$datatype
#> [1] "interval"
#>
#> $aucint.inf.obs$pptestcd_cdisc
#> [1] "AUCINTIS"
#>
#> $aucint.inf.obs$pptest_cdisc
#> [1] "AUCint (based on AUCinf,obs extrapolation)"
#>
#>
#> $aucint.inf.obs.dose
#> $aucint.inf.obs.dose$FUN
#> [1] "pk.calc.aucint.inf.obs"
#>
#> $aucint.inf.obs.dose$values
#> [1] FALSE TRUE
#>
#> $aucint.inf.obs.dose$unit_type
#> [1] "auc"
#>
#> $aucint.inf.obs.dose$pretty_name
#> [1] "AUCint (based on AUCinf,obs extrapolation, dose-aware)"
#>
#> $aucint.inf.obs.dose$desc
#> [1] "AUC T1 to T2, dose-aware (AUCinf,obs)"
#>
#> $aucint.inf.obs.dose$sparse
#> [1] FALSE
#>
#> $aucint.inf.obs.dose$formalsmap
#> $aucint.inf.obs.dose$formalsmap$conc
#> [1] "conc.group"
#>
#> $aucint.inf.obs.dose$formalsmap$time
#> [1] "time.group"
#>
#> $aucint.inf.obs.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#>
#>
#> $aucint.inf.obs.dose$depends
#> [1] "lambda.z" "clast.obs"
#>
#> $aucint.inf.obs.dose$datatype
#> [1] "interval"
#>
#> $aucint.inf.obs.dose$pptestcd_cdisc
#> [1] "AUCINTID"
#>
#> $aucint.inf.obs.dose$pptest_cdisc
#> [1] "AUCint (based on AUCinf,obs extrapolation, dose-aware)"
#>
#>
#> $aucint.inf.pred
#> $aucint.inf.pred$FUN
#> [1] "pk.calc.aucint.inf.pred"
#>
#> $aucint.inf.pred$values
#> [1] FALSE TRUE
#>
#> $aucint.inf.pred$unit_type
#> [1] "auc"
#>
#> $aucint.inf.pred$pretty_name
#> [1] "AUCint (based on AUCinf,pred extrapolation)"
#>
#> $aucint.inf.pred$desc
#> [1] "AUC from T1 to T2 (AUCinf,pred extrap)"
#>
#> $aucint.inf.pred$sparse
#> [1] FALSE
#>
#> $aucint.inf.pred$formalsmap
#> $aucint.inf.pred$formalsmap$conc
#> [1] "conc.group"
#>
#> $aucint.inf.pred$formalsmap$time
#> [1] "time.group"
#>
#> $aucint.inf.pred$formalsmap$time.dose
#> NULL
#>
#>
#> $aucint.inf.pred$depends
#> [1] "lambda.z" "clast.pred"
#>
#> $aucint.inf.pred$datatype
#> [1] "interval"
#>
#> $aucint.inf.pred$pptestcd_cdisc
#> [1] "AUCINTIP"
#>
#> $aucint.inf.pred$pptest_cdisc
#> [1] "AUCint (based on AUCinf,pred extrapolation)"
#>
#>
#> $aucint.inf.pred.dose
#> $aucint.inf.pred.dose$FUN
#> [1] "pk.calc.aucint.inf.pred"
#>
#> $aucint.inf.pred.dose$values
#> [1] FALSE TRUE
#>
#> $aucint.inf.pred.dose$unit_type
#> [1] "auc"
#>
#> $aucint.inf.pred.dose$pretty_name
#> [1] "AUCint (based on AUCinf,pred extrapolation, dose-aware)"
#>
#> $aucint.inf.pred.dose$desc
#> [1] "AUC T1 to T2, dose-aware (AUCinf,pred)"
#>
#> $aucint.inf.pred.dose$sparse
#> [1] FALSE
#>
#> $aucint.inf.pred.dose$formalsmap
#> $aucint.inf.pred.dose$formalsmap$conc
#> [1] "conc.group"
#>
#> $aucint.inf.pred.dose$formalsmap$time
#> [1] "time.group"
#>
#> $aucint.inf.pred.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#>
#>
#> $aucint.inf.pred.dose$depends
#> [1] "lambda.z" "clast.pred"
#>
#> $aucint.inf.pred.dose$datatype
#> [1] "interval"
#>
#> $aucint.inf.pred.dose$pptestcd_cdisc
#> [1] "AUCINTPD"
#>
#> $aucint.inf.pred.dose$pptest_cdisc
#> [1] "AUCint (based on AUCinf,pred extrapolation, dose-aware)"
#>
#>
#> $aumcint.inf.obs
#> $aumcint.inf.obs$FUN
#> [1] "pk.calc.aumcint.inf.obs"
#>
#> $aumcint.inf.obs$values
#> [1] FALSE TRUE
#>
#> $aumcint.inf.obs$unit_type
#> [1] "aumc"
#>
#> $aumcint.inf.obs$pretty_name
#> [1] "AUMCint (based on AUMCinf,obs extrapolation)"
#>
#> $aumcint.inf.obs$desc
#> [1] "AUMC from T1 to T2 (AUMCinf,obs extrap)"
#>
#> $aumcint.inf.obs$sparse
#> [1] FALSE
#>
#> $aumcint.inf.obs$formalsmap
#> $aumcint.inf.obs$formalsmap$conc
#> [1] "conc.group"
#>
#> $aumcint.inf.obs$formalsmap$time
#> [1] "time.group"
#>
#> $aumcint.inf.obs$formalsmap$time.dose
#> NULL
#>
#>
#> $aumcint.inf.obs$depends
#> [1] "lambda.z" "clast.obs"
#>
#> $aumcint.inf.obs$datatype
#> [1] "interval"
#>
#> $aumcint.inf.obs$pptestcd_cdisc
#> [1] "aumcint.inf.obs"
#>
#> $aumcint.inf.obs$pptest_cdisc
#> [1] "AUMC from T1 to T2 (AUMCinf,obs extrap)"
#>
#>
#> $aumcint.inf.obs.dose
#> $aumcint.inf.obs.dose$FUN
#> [1] "pk.calc.aumcint.inf.obs"
#>
#> $aumcint.inf.obs.dose$values
#> [1] FALSE TRUE
#>
#> $aumcint.inf.obs.dose$unit_type
#> [1] "aumc"
#>
#> $aumcint.inf.obs.dose$pretty_name
#> [1] "AUMCint (based on AUMCinf,obs extrapolation, dose-aware)"
#>
#> $aumcint.inf.obs.dose$desc
#> [1] "AUMC T1 to T2, dose-aware (AUMCinf,obs)"
#>
#> $aumcint.inf.obs.dose$sparse
#> [1] FALSE
#>
#> $aumcint.inf.obs.dose$formalsmap
#> $aumcint.inf.obs.dose$formalsmap$conc
#> [1] "conc.group"
#>
#> $aumcint.inf.obs.dose$formalsmap$time
#> [1] "time.group"
#>
#> $aumcint.inf.obs.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#>
#>
#> $aumcint.inf.obs.dose$depends
#> [1] "lambda.z" "clast.obs"
#>
#> $aumcint.inf.obs.dose$datatype
#> [1] "interval"
#>
#> $aumcint.inf.obs.dose$pptestcd_cdisc
#> [1] "aumcint.inf.obs.dose"
#>
#> $aumcint.inf.obs.dose$pptest_cdisc
#> [1] "AUMC T1 to T2, dose-aware (AUMCinf,obs)"
#>
#>
#> $aumcint.inf.pred
#> $aumcint.inf.pred$FUN
#> [1] "pk.calc.aumcint.inf.pred"
#>
#> $aumcint.inf.pred$values
#> [1] FALSE TRUE
#>
#> $aumcint.inf.pred$unit_type
#> [1] "aumc"
#>
#> $aumcint.inf.pred$pretty_name
#> [1] "AUMCint (based on AUMCinf,pred extrapolation)"
#>
#> $aumcint.inf.pred$desc
#> [1] "AUMC from T1 to T2 (AUMCinf,pred extrap)"
#>
#> $aumcint.inf.pred$sparse
#> [1] FALSE
#>
#> $aumcint.inf.pred$formalsmap
#> $aumcint.inf.pred$formalsmap$conc
#> [1] "conc.group"
#>
#> $aumcint.inf.pred$formalsmap$time
#> [1] "time.group"
#>
#> $aumcint.inf.pred$formalsmap$time.dose
#> NULL
#>
#>
#> $aumcint.inf.pred$depends
#> [1] "lambda.z" "clast.pred"
#>
#> $aumcint.inf.pred$datatype
#> [1] "interval"
#>
#> $aumcint.inf.pred$pptestcd_cdisc
#> [1] "aumcint.inf.pred"
#>
#> $aumcint.inf.pred$pptest_cdisc
#> [1] "AUMC from T1 to T2 (AUMCinf,pred extrap)"
#>
#>
#> $aumcint.inf.pred.dose
#> $aumcint.inf.pred.dose$FUN
#> [1] "pk.calc.aumcint.inf.pred"
#>
#> $aumcint.inf.pred.dose$values
#> [1] FALSE TRUE
#>
#> $aumcint.inf.pred.dose$unit_type
#> [1] "aumc"
#>
#> $aumcint.inf.pred.dose$pretty_name
#> [1] "AUMCint (based on AUMCinf,pred extrapolation, dose-aware)"
#>
#> $aumcint.inf.pred.dose$desc
#> [1] "AUMC T1 to T2, dose-aware (AUMCinf,pred)"
#>
#> $aumcint.inf.pred.dose$sparse
#> [1] FALSE
#>
#> $aumcint.inf.pred.dose$formalsmap
#> $aumcint.inf.pred.dose$formalsmap$conc
#> [1] "conc.group"
#>
#> $aumcint.inf.pred.dose$formalsmap$time
#> [1] "time.group"
#>
#> $aumcint.inf.pred.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#>
#>
#> $aumcint.inf.pred.dose$depends
#> [1] "lambda.z" "clast.pred"
#>
#> $aumcint.inf.pred.dose$datatype
#> [1] "interval"
#>
#> $aumcint.inf.pred.dose$pptestcd_cdisc
#> [1] "aumcint.inf.pred.dose"
#>
#> $aumcint.inf.pred.dose$pptest_cdisc
#> [1] "AUMC T1 to T2, dose-aware (AUMCinf,pred)"
#>
#>
#> $aucivinf.obs
#> $aucivinf.obs$FUN
#> [1] "pk.calc.auciv"
#>
#> $aucivinf.obs$values
#> [1] FALSE TRUE
#>
#> $aucivinf.obs$unit_type
#> [1] "auc"
#>
#> $aucivinf.obs$pretty_name
#> [1] "AUCinf,obs (IV dosing)"
#>
#> $aucivinf.obs$desc
#> [1] "AUCinf.obs, IV back-extrap C0"
#>
#> $aucivinf.obs$sparse
#> [1] FALSE
#>
#> $aucivinf.obs$formalsmap
#> $aucivinf.obs$formalsmap$auc
#> [1] "aucinf.obs"
#>
#>
#> $aucivinf.obs$depends
#> [1] "aucinf.obs" "c0"
#>
#> $aucivinf.obs$datatype
#> [1] "interval"
#>
#> $aucivinf.obs$pptestcd_cdisc
#> [1] "AUCIVIS"
#>
#> $aucivinf.obs$pptest_cdisc
#> [1] "AUCinf,obs (IV dosing)"
#>
#>
#> $aucivinf.pred
#> $aucivinf.pred$FUN
#> [1] "pk.calc.auciv"
#>
#> $aucivinf.pred$values
#> [1] FALSE TRUE
#>
#> $aucivinf.pred$unit_type
#> [1] "auc"
#>
#> $aucivinf.pred$pretty_name
#> [1] "AUCinf,pred (IV dosing)"
#>
#> $aucivinf.pred$desc
#> [1] "AUCinf.pred, IV back-extrap C0"
#>
#> $aucivinf.pred$sparse
#> [1] FALSE
#>
#> $aucivinf.pred$formalsmap
#> $aucivinf.pred$formalsmap$auc
#> [1] "aucinf.pred"
#>
#>
#> $aucivinf.pred$depends
#> [1] "aucinf.pred" "c0"
#>
#> $aucivinf.pred$datatype
#> [1] "interval"
#>
#> $aucivinf.pred$pptestcd_cdisc
#> [1] "AUCIVIP"
#>
#> $aucivinf.pred$pptest_cdisc
#> [1] "AUCinf,pred (IV dosing)"
#>
#>
#> $aucivpbextinf.obs
#> $aucivpbextinf.obs$FUN
#> [1] "pk.calc.auciv_pbext"
#>
#> $aucivpbextinf.obs$values
#> [1] FALSE TRUE
#>
#> $aucivpbextinf.obs$unit_type
#> [1] "%"
#>
#> $aucivpbextinf.obs$pretty_name
#> [1] "AUCbext (based on AUCinf,obs)"
#>
#> $aucivpbextinf.obs$desc
#> [1] "Back-extrap %, IV, AUCinf.obs"
#>
#> $aucivpbextinf.obs$sparse
#> [1] FALSE
#>
#> $aucivpbextinf.obs$formalsmap
#> $aucivpbextinf.obs$formalsmap$auc
#> [1] "aucinf.obs"
#>
#> $aucivpbextinf.obs$formalsmap$auciv
#> [1] "aucivinf.obs"
#>
#>
#> $aucivpbextinf.obs$depends
#> [1] "aucinf.obs" "aucivinf.obs"
#>
#> $aucivpbextinf.obs$datatype
#> [1] "interval"
#>
#> $aucivpbextinf.obs$pptestcd_cdisc
#> [1] "AUCIVPEI"
#>
#> $aucivpbextinf.obs$pptest_cdisc
#> [1] "AUCbext (based on AUCinf,obs)"
#>
#>
#> $aucivpbextinf.pred
#> $aucivpbextinf.pred$FUN
#> [1] "pk.calc.auciv_pbext"
#>
#> $aucivpbextinf.pred$values
#> [1] FALSE TRUE
#>
#> $aucivpbextinf.pred$unit_type
#> [1] "%"
#>
#> $aucivpbextinf.pred$pretty_name
#> [1] "AUCbext (based on AUCinf,pred)"
#>
#> $aucivpbextinf.pred$desc
#> [1] "Back-extrap %, IV, AUCinf.pred"
#>
#> $aucivpbextinf.pred$sparse
#> [1] FALSE
#>
#> $aucivpbextinf.pred$formalsmap
#> $aucivpbextinf.pred$formalsmap$auc
#> [1] "aucinf.pred"
#>
#> $aucivpbextinf.pred$formalsmap$auciv
#> [1] "aucivinf.pred"
#>
#>
#> $aucivpbextinf.pred$depends
#> [1] "aucinf.pred" "aucivinf.pred"
#>
#> $aucivpbextinf.pred$datatype
#> [1] "interval"
#>
#> $aucivpbextinf.pred$pptestcd_cdisc
#> [1] "AUCIVPEP"
#>
#> $aucivpbextinf.pred$pptest_cdisc
#> [1] "AUCbext (based on AUCinf,pred)"
#>
#>
#> $aumcivinf.obs
#> $aumcivinf.obs$FUN
#> [1] "pk.calc.aumciv"
#>
#> $aumcivinf.obs$values
#> [1] FALSE TRUE
#>
#> $aumcivinf.obs$unit_type
#> [1] "aumc"
#>
#> $aumcivinf.obs$pretty_name
#> [1] "AUMCinf,obs (IV dosing)"
#>
#> $aumcivinf.obs$desc
#> [1] "AUMCinf.obs, IV back-extrap C0"
#>
#> $aumcivinf.obs$sparse
#> [1] FALSE
#>
#> $aumcivinf.obs$formalsmap
#> $aumcivinf.obs$formalsmap$aumc
#> [1] "aumcinf.obs"
#>
#>
#> $aumcivinf.obs$depends
#> [1] "aumcinf.obs" "c0"
#>
#> $aumcivinf.obs$datatype
#> [1] "interval"
#>
#> $aumcivinf.obs$pptestcd_cdisc
#> [1] "aumcivinf.obs"
#>
#> $aumcivinf.obs$pptest_cdisc
#> [1] "AUMCinf.obs, IV back-extrap C0"
#>
#>
#> $aumcivinf.pred
#> $aumcivinf.pred$FUN
#> [1] "pk.calc.aumciv"
#>
#> $aumcivinf.pred$values
#> [1] FALSE TRUE
#>
#> $aumcivinf.pred$unit_type
#> [1] "aumc"
#>
#> $aumcivinf.pred$pretty_name
#> [1] "AUMCinf,pred (IV dosing)"
#>
#> $aumcivinf.pred$desc
#> [1] "AUMCinf.pred, IV back-extrap C0"
#>
#> $aumcivinf.pred$sparse
#> [1] FALSE
#>
#> $aumcivinf.pred$formalsmap
#> $aumcivinf.pred$formalsmap$aumc
#> [1] "aumcinf.pred"
#>
#>
#> $aumcivinf.pred$depends
#> [1] "aumcinf.pred" "c0"
#>
#> $aumcivinf.pred$datatype
#> [1] "interval"
#>
#> $aumcivinf.pred$pptestcd_cdisc
#> [1] "aumcivinf.pred"
#>
#> $aumcivinf.pred$pptest_cdisc
#> [1] "AUMCinf.pred, IV back-extrap C0"
#>
#>
#> $aucpext.obs
#> $aucpext.obs$FUN
#> [1] "pk.calc.aucpext"
#>
#> $aucpext.obs$values
#> [1] FALSE TRUE
#>
#> $aucpext.obs$unit_type
#> [1] "%"
#>
#> $aucpext.obs$pretty_name
#> [1] "AUCpext (based on AUCinf,obs)"
#>
#> $aucpext.obs$desc
#> [1] "% AUCinf extrap after Tlast, obs"
#>
#> $aucpext.obs$sparse
#> [1] FALSE
#>
#> $aucpext.obs$formalsmap
#> $aucpext.obs$formalsmap$aucinf
#> [1] "aucinf.obs"
#>
#>
#> $aucpext.obs$depends
#> [1] "auclast" "aucinf.obs"
#>
#> $aucpext.obs$datatype
#> [1] "interval"
#>
#> $aucpext.obs$pptestcd_cdisc
#> [1] "AUCPEO"
#>
#> $aucpext.obs$pptest_cdisc
#> [1] "AUC %Extrapolation Obs"
#>
#>
#> $aucpext.pred
#> $aucpext.pred$FUN
#> [1] "pk.calc.aucpext"
#>
#> $aucpext.pred$values
#> [1] FALSE TRUE
#>
#> $aucpext.pred$unit_type
#> [1] "%"
#>
#> $aucpext.pred$pretty_name
#> [1] "AUCpext (based on AUCinf,pred)"
#>
#> $aucpext.pred$desc
#> [1] "% AUCinf extrap after Tlast, pred"
#>
#> $aucpext.pred$sparse
#> [1] FALSE
#>
#> $aucpext.pred$formalsmap
#> $aucpext.pred$formalsmap$aucinf
#> [1] "aucinf.pred"
#>
#>
#> $aucpext.pred$depends
#> [1] "auclast" "aucinf.pred"
#>
#> $aucpext.pred$datatype
#> [1] "interval"
#>
#> $aucpext.pred$pptestcd_cdisc
#> [1] "AUCPEP"
#>
#> $aucpext.pred$pptest_cdisc
#> [1] "AUC %Extrapolation Pred"
#>
#>
#> $kel.iv.all
#> $kel.iv.all$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.iv.all$values
#> [1] FALSE TRUE
#>
#> $kel.iv.all$unit_type
#> [1] "inverse_time"
#>
#> $kel.iv.all$pretty_name
#> [1] "Kel (for IV dosing, based on AUCall)"
#>
#> $kel.iv.all$desc
#> [1] "Elim rate, IV MRTall"
#>
#> $kel.iv.all$sparse
#> [1] FALSE
#>
#> $kel.iv.all$formalsmap
#> $kel.iv.all$formalsmap$mrt
#> [1] "mrt.iv.all"
#>
#>
#> $kel.iv.all$depends
#> [1] "mrt.iv.all"
#>
#> $kel.iv.all$datatype
#> [1] "interval"
#>
#> $kel.iv.all$pptestcd_cdisc
#> [1] "kel.iv.all"
#>
#> $kel.iv.all$pptest_cdisc
#> [1] "Elim rate, IV MRTall"
#>
#>
#> $kel.ivint.all
#> $kel.ivint.all$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.ivint.all$values
#> [1] FALSE TRUE
#>
#> $kel.ivint.all$unit_type
#> [1] "inverse_time"
#>
#> $kel.ivint.all$pretty_name
#> [1] "Kel (IV dose interval, based on AUCint.all)"
#>
#> $kel.ivint.all$desc
#> [1] "Elim rate, IV MRTint.all"
#>
#> $kel.ivint.all$sparse
#> [1] FALSE
#>
#> $kel.ivint.all$formalsmap
#> $kel.ivint.all$formalsmap$mrt
#> [1] "mrt.ivint.all"
#>
#>
#> $kel.ivint.all$depends
#> [1] "mrt.ivint.all"
#>
#> $kel.ivint.all$datatype
#> [1] "interval"
#>
#> $kel.ivint.all$pptestcd_cdisc
#> [1] "kel.ivint.all"
#>
#> $kel.ivint.all$pptest_cdisc
#> [1] "Elim rate, IV MRTint.all"
#>
#>
#> $kel.ivint.last
#> $kel.ivint.last$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.ivint.last$values
#> [1] FALSE TRUE
#>
#> $kel.ivint.last$unit_type
#> [1] "inverse_time"
#>
#> $kel.ivint.last$pretty_name
#> [1] "Kel (IV dose interval, based on AUCint.last)"
#>
#> $kel.ivint.last$desc
#> [1] "Elim rate, IV MRTint.last"
#>
#> $kel.ivint.last$sparse
#> [1] FALSE
#>
#> $kel.ivint.last$formalsmap
#> $kel.ivint.last$formalsmap$mrt
#> [1] "mrt.ivint.last"
#>
#>
#> $kel.ivint.last$depends
#> [1] "mrt.ivint.last"
#>
#> $kel.ivint.last$datatype
#> [1] "interval"
#>
#> $kel.ivint.last$pptestcd_cdisc
#> [1] "kel.ivint.last"
#>
#> $kel.ivint.last$pptest_cdisc
#> [1] "Elim rate, IV MRTint.last"
#>
#>
#> $kel.sparse.last
#> $kel.sparse.last$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.sparse.last$values
#> [1] FALSE TRUE
#>
#> $kel.sparse.last$unit_type
#> [1] "inverse_time"
#>
#> $kel.sparse.last$pretty_name
#> [1] "Kel (for sparse data, based on AUClast)"
#>
#> $kel.sparse.last$desc
#> [1] "Elim rate, sparse MRTlast"
#>
#> $kel.sparse.last$sparse
#> [1] TRUE
#>
#> $kel.sparse.last$formalsmap
#> $kel.sparse.last$formalsmap$mrt
#> [1] "mrt.sparse.last"
#>
#>
#> $kel.sparse.last$depends
#> [1] "mrt.sparse.last"
#>
#> $kel.sparse.last$datatype
#> [1] "interval"
#>
#> $kel.sparse.last$pptestcd_cdisc
#> [1] "kel.sparse.last"
#>
#> $kel.sparse.last$pptest_cdisc
#> [1] "Elim rate, sparse MRTlast"
#>
#>
#> $cl.obs
#> $cl.obs$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.obs$values
#> [1] FALSE TRUE
#>
#> $cl.obs$unit_type
#> [1] "clearance"
#>
#> $cl.obs$pretty_name
#> [1] "CL (based on AUCinf,obs)"
#>
#> $cl.obs$desc
#> [1] "Clearance, observed Clast"
#>
#> $cl.obs$sparse
#> [1] FALSE
#>
#> $cl.obs$formalsmap
#> $cl.obs$formalsmap$auc
#> [1] "aucinf.obs"
#>
#>
#> $cl.obs$depends
#> [1] "aucinf.obs"
#>
#> $cl.obs$datatype
#> [1] "interval"
#>
#> $cl.obs$pptestcd_cdisc
#> $cl.obs$pptestcd_cdisc$route
#> $cl.obs$pptestcd_cdisc$route$extravascular
#> [1] "CLF/FO"
#>
#> $cl.obs$pptestcd_cdisc$route$intravascular
#> [1] "CLO"
#>
#>
#>
#> $cl.obs$pptest_cdisc
#> $cl.obs$pptest_cdisc$route
#> $cl.obs$pptest_cdisc$route$extravascular
#> [1] "Total CL Obs by F"
#>
#> $cl.obs$pptest_cdisc$route$intravascular
#> [1] "Total CL Obs"
#>
#>
#>
#>
#> $cl.pred
#> $cl.pred$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.pred$values
#> [1] FALSE TRUE
#>
#> $cl.pred$unit_type
#> [1] "clearance"
#>
#> $cl.pred$pretty_name
#> [1] "CL (based on AUCinf,pred)"
#>
#> $cl.pred$desc
#> [1] "Clearance, predicted Clast"
#>
#> $cl.pred$sparse
#> [1] FALSE
#>
#> $cl.pred$formalsmap
#> $cl.pred$formalsmap$auc
#> [1] "aucinf.pred"
#>
#>
#> $cl.pred$depends
#> [1] "aucinf.pred"
#>
#> $cl.pred$datatype
#> [1] "interval"
#>
#> $cl.pred$pptestcd_cdisc
#> $cl.pred$pptestcd_cdisc$route
#> $cl.pred$pptestcd_cdisc$route$extravascular
#> [1] "CLF/FP"
#>
#> $cl.pred$pptestcd_cdisc$route$intravascular
#> [1] "CLP"
#>
#>
#>
#> $cl.pred$pptest_cdisc
#> $cl.pred$pptest_cdisc$route
#> $cl.pred$pptest_cdisc$route$extravascular
#> [1] "Total CL Pred by F"
#>
#> $cl.pred$pptest_cdisc$route$intravascular
#> [1] "Total CL Pred"
#>
#>
#>
#>
#> $cl.int.inf.obs
#> $cl.int.inf.obs$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.int.inf.obs$values
#> [1] FALSE TRUE
#>
#> $cl.int.inf.obs$unit_type
#> [1] "clearance"
#>
#> $cl.int.inf.obs$pretty_name
#> [1] "CL (based on AUCint.inf.obs)"
#>
#> $cl.int.inf.obs$desc
#> [1] "Clearance, AUCint.inf.obs"
#>
#> $cl.int.inf.obs$sparse
#> [1] FALSE
#>
#> $cl.int.inf.obs$formalsmap
#> $cl.int.inf.obs$formalsmap$auc
#> [1] "aucint.inf.obs"
#>
#>
#> $cl.int.inf.obs$depends
#> [1] "aucint.inf.obs"
#>
#> $cl.int.inf.obs$datatype
#> [1] "interval"
#>
#> $cl.int.inf.obs$pptestcd_cdisc
#> [1] "cl.int.inf.obs"
#>
#> $cl.int.inf.obs$pptest_cdisc
#> [1] "Clearance, AUCint.inf.obs"
#>
#>
#> $cl.int.inf.pred
#> $cl.int.inf.pred$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.int.inf.pred$values
#> [1] FALSE TRUE
#>
#> $cl.int.inf.pred$unit_type
#> [1] "clearance"
#>
#> $cl.int.inf.pred$pretty_name
#> [1] "CL (based on AUCint.inf.pred)"
#>
#> $cl.int.inf.pred$desc
#> [1] "Clearance, AUCint.inf.pred"
#>
#> $cl.int.inf.pred$sparse
#> [1] FALSE
#>
#> $cl.int.inf.pred$formalsmap
#> $cl.int.inf.pred$formalsmap$auc
#> [1] "aucint.inf.pred"
#>
#>
#> $cl.int.inf.pred$depends
#> [1] "aucint.inf.pred"
#>
#> $cl.int.inf.pred$datatype
#> [1] "interval"
#>
#> $cl.int.inf.pred$pptestcd_cdisc
#> [1] "cl.int.inf.pred"
#>
#> $cl.int.inf.pred$pptest_cdisc
#> [1] "Clearance, AUCint.inf.pred"
#>
#>
#> $cl.iv.obs
#> $cl.iv.obs$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.iv.obs$values
#> [1] FALSE TRUE
#>
#> $cl.iv.obs$unit_type
#> [1] "clearance"
#>
#> $cl.iv.obs$pretty_name
#> [1] "CL (for IV dosing, based on AUCinf,obs)"
#>
#> $cl.iv.obs$desc
#> [1] "IV clearance, AUCinf.obs"
#>
#> $cl.iv.obs$sparse
#> [1] FALSE
#>
#> $cl.iv.obs$formalsmap
#> $cl.iv.obs$formalsmap$auc
#> [1] "aucivinf.obs"
#>
#>
#> $cl.iv.obs$depends
#> [1] "aucivinf.obs"
#>
#> $cl.iv.obs$datatype
#> [1] "interval"
#>
#> $cl.iv.obs$pptestcd_cdisc
#> [1] "cl.iv.obs"
#>
#> $cl.iv.obs$pptest_cdisc
#> [1] "IV clearance, AUCinf.obs"
#>
#>
#> $cl.iv.pred
#> $cl.iv.pred$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.iv.pred$values
#> [1] FALSE TRUE
#>
#> $cl.iv.pred$unit_type
#> [1] "clearance"
#>
#> $cl.iv.pred$pretty_name
#> [1] "CL (for IV dosing, based on AUCinf,pred)"
#>
#> $cl.iv.pred$desc
#> [1] "IV clearance, AUCinf.pred"
#>
#> $cl.iv.pred$sparse
#> [1] FALSE
#>
#> $cl.iv.pred$formalsmap
#> $cl.iv.pred$formalsmap$auc
#> [1] "aucivinf.pred"
#>
#>
#> $cl.iv.pred$depends
#> [1] "aucivinf.pred"
#>
#> $cl.iv.pred$datatype
#> [1] "interval"
#>
#> $cl.iv.pred$pptestcd_cdisc
#> [1] "cl.iv.pred"
#>
#> $cl.iv.pred$pptest_cdisc
#> [1] "IV clearance, AUCinf.pred"
#>
#>
#> $mrt.obs
#> $mrt.obs$FUN
#> [1] "pk.calc.mrt"
#>
#> $mrt.obs$values
#> [1] FALSE TRUE
#>
#> $mrt.obs$unit_type
#> [1] "time"
#>
#> $mrt.obs$pretty_name
#> [1] "MRT (based on AUCinf,obs)"
#>
#> $mrt.obs$desc
#> [1] "MRT to inf, observed Clast"
#>
#> $mrt.obs$sparse
#> [1] FALSE
#>
#> $mrt.obs$formalsmap
#> $mrt.obs$formalsmap$auc
#> [1] "aucinf.obs"
#>
#> $mrt.obs$formalsmap$aumc
#> [1] "aumcinf.obs"
#>
#>
#> $mrt.obs$depends
#> [1] "aucinf.obs" "aumcinf.obs"
#>
#> $mrt.obs$datatype
#> [1] "interval"
#>
#> $mrt.obs$pptestcd_cdisc
#> $mrt.obs$pptestcd_cdisc$route
#> $mrt.obs$pptestcd_cdisc$route$extravascular
#> [1] "MRTEVFO"
#>
#> $mrt.obs$pptestcd_cdisc$route$intravascular
#> [1] "MRTICFO"
#>
#>
#>
#> $mrt.obs$pptest_cdisc
#> $mrt.obs$pptest_cdisc$route
#> $mrt.obs$pptest_cdisc$route$extravascular
#> [1] "MRT Extravasc Infinity Obs"
#>
#> $mrt.obs$pptest_cdisc$route$intravascular
#> [1] "MRT IV Cont Inf Infinity Obs"
#>
#>
#>
#>
#> $mrt.pred
#> $mrt.pred$FUN
#> [1] "pk.calc.mrt"
#>
#> $mrt.pred$values
#> [1] FALSE TRUE
#>
#> $mrt.pred$unit_type
#> [1] "time"
#>
#> $mrt.pred$pretty_name
#> [1] "MRT (based on AUCinf,pred)"
#>
#> $mrt.pred$desc
#> [1] "MRT to inf, predicted Clast"
#>
#> $mrt.pred$sparse
#> [1] FALSE
#>
#> $mrt.pred$formalsmap
#> $mrt.pred$formalsmap$auc
#> [1] "aucinf.pred"
#>
#> $mrt.pred$formalsmap$aumc
#> [1] "aumcinf.pred"
#>
#>
#> $mrt.pred$depends
#> [1] "aucinf.pred" "aumcinf.pred"
#>
#> $mrt.pred$datatype
#> [1] "interval"
#>
#> $mrt.pred$pptestcd_cdisc
#> $mrt.pred$pptestcd_cdisc$route
#> $mrt.pred$pptestcd_cdisc$route$extravascular
#> [1] "MRTEVFP"
#>
#> $mrt.pred$pptestcd_cdisc$route$intravascular
#> [1] "MRTICFP"
#>
#>
#>
#> $mrt.pred$pptest_cdisc
#> $mrt.pred$pptest_cdisc$route
#> $mrt.pred$pptest_cdisc$route$extravascular
#> [1] "MRT Extravasc Infinity Pred"
#>
#> $mrt.pred$pptest_cdisc$route$intravascular
#> [1] "MRT IV Cont Inf Infinity Pred"
#>
#>
#>
#>
#> $mrt.int.inf.obs
#> $mrt.int.inf.obs$FUN
#> [1] "pk.calc.mrt"
#>
#> $mrt.int.inf.obs$values
#> [1] FALSE TRUE
#>
#> $mrt.int.inf.obs$unit_type
#> [1] "time"
#>
#> $mrt.int.inf.obs$pretty_name
#> [1] "MRT (based on AUCint.inf.obs)"
#>
#> $mrt.int.inf.obs$desc
#> [1] "MRT, interval AUC/AUMCinf obs"
#>
#> $mrt.int.inf.obs$sparse
#> [1] FALSE
#>
#> $mrt.int.inf.obs$formalsmap
#> $mrt.int.inf.obs$formalsmap$auc
#> [1] "aucint.inf.obs"
#>
#> $mrt.int.inf.obs$formalsmap$aumc
#> [1] "aumcint.inf.obs"
#>
#>
#> $mrt.int.inf.obs$depends
#> [1] "aucint.inf.obs" "aumcint.inf.obs"
#>
#> $mrt.int.inf.obs$datatype
#> [1] "interval"
#>
#> $mrt.int.inf.obs$pptestcd_cdisc
#> [1] "mrt.int.inf.obs"
#>
#> $mrt.int.inf.obs$pptest_cdisc
#> [1] "MRT, interval AUC/AUMCinf obs"
#>
#>
#> $mrt.int.inf.pred
#> $mrt.int.inf.pred$FUN
#> [1] "pk.calc.mrt"
#>
#> $mrt.int.inf.pred$values
#> [1] FALSE TRUE
#>
#> $mrt.int.inf.pred$unit_type
#> [1] "time"
#>
#> $mrt.int.inf.pred$pretty_name
#> [1] "MRT (based on AUCint.inf.pred)"
#>
#> $mrt.int.inf.pred$desc
#> [1] "MRT, interval AUC/AUMCinf pred"
#>
#> $mrt.int.inf.pred$sparse
#> [1] FALSE
#>
#> $mrt.int.inf.pred$formalsmap
#> $mrt.int.inf.pred$formalsmap$auc
#> [1] "aucint.inf.pred"
#>
#> $mrt.int.inf.pred$formalsmap$aumc
#> [1] "aumcint.inf.pred"
#>
#>
#> $mrt.int.inf.pred$depends
#> [1] "aucint.inf.pred" "aumcint.inf.pred"
#>
#> $mrt.int.inf.pred$datatype
#> [1] "interval"
#>
#> $mrt.int.inf.pred$pptestcd_cdisc
#> [1] "mrt.int.inf.pred"
#>
#> $mrt.int.inf.pred$pptest_cdisc
#> [1] "MRT, interval AUC/AUMCinf pred"
#>
#>
#> $mrt.iv.obs
#> $mrt.iv.obs$FUN
#> [1] "pk.calc.mrt.iv"
#>
#> $mrt.iv.obs$values
#> [1] FALSE TRUE
#>
#> $mrt.iv.obs$unit_type
#> [1] "time"
#>
#> $mrt.iv.obs$pretty_name
#> [1] "MRT (for IV dosing, based on AUCinf,obs)"
#>
#> $mrt.iv.obs$desc
#> [1] "IV MRT, AUCinf.obs/AUMCinf.obs"
#>
#> $mrt.iv.obs$sparse
#> [1] FALSE
#>
#> $mrt.iv.obs$formalsmap
#> $mrt.iv.obs$formalsmap$auc
#> [1] "aucinf.obs"
#>
#> $mrt.iv.obs$formalsmap$aumc
#> [1] "aumcinf.obs"
#>
#>
#> $mrt.iv.obs$depends
#> [1] "aucinf.obs" "aumcinf.obs"
#>
#> $mrt.iv.obs$datatype
#> [1] "interval"
#>
#> $mrt.iv.obs$pptestcd_cdisc
#> [1] "MRTIBIFO"
#>
#> $mrt.iv.obs$pptest_cdisc
#> [1] "MRT Intravasc Infinity Obs"
#>
#>
#> $mrt.iv.pred
#> $mrt.iv.pred$FUN
#> [1] "pk.calc.mrt.iv"
#>
#> $mrt.iv.pred$values
#> [1] FALSE TRUE
#>
#> $mrt.iv.pred$unit_type
#> [1] "time"
#>
#> $mrt.iv.pred$pretty_name
#> [1] "MRT (for IV dosing, based on AUCinf,pred)"
#>
#> $mrt.iv.pred$desc
#> [1] "IV MRT, AUCinf.pred/AUMCinf.pred"
#>
#> $mrt.iv.pred$sparse
#> [1] FALSE
#>
#> $mrt.iv.pred$formalsmap
#> $mrt.iv.pred$formalsmap$auc
#> [1] "aucinf.pred"
#>
#> $mrt.iv.pred$formalsmap$aumc
#> [1] "aumcinf.pred"
#>
#>
#> $mrt.iv.pred$depends
#> [1] "aucinf.pred" "aumcinf.pred"
#>
#> $mrt.iv.pred$datatype
#> [1] "interval"
#>
#> $mrt.iv.pred$pptestcd_cdisc
#> [1] "MRTIBIFP"
#>
#> $mrt.iv.pred$pptest_cdisc
#> [1] "MRT Intravasc Infinity Pred"
#>
#>
#> $mrt.md.obs
#> $mrt.md.obs$FUN
#> [1] "pk.calc.mrt.md"
#>
#> $mrt.md.obs$values
#> [1] FALSE TRUE
#>
#> $mrt.md.obs$unit_type
#> [1] "time"
#>
#> $mrt.md.obs$pretty_name
#> [1] "MRT (for multiple dosing, based on AUCinf,obs)"
#>
#> $mrt.md.obs$desc
#> [1] "MRT, multi-dose AUCinf.obs/AUMCinf.obs"
#>
#> $mrt.md.obs$sparse
#> [1] FALSE
#>
#> $mrt.md.obs$formalsmap
#> $mrt.md.obs$formalsmap$auctau
#> [1] "auclast"
#>
#> $mrt.md.obs$formalsmap$aumctau
#> [1] "aumclast"
#>
#> $mrt.md.obs$formalsmap$aucinf
#> [1] "aucinf.obs"
#>
#>
#> $mrt.md.obs$depends
#> [1] "auclast" "aumclast" "aucinf.obs"
#>
#> $mrt.md.obs$datatype
#> [1] "interval"
#>
#> $mrt.md.obs$pptestcd_cdisc
#> [1] "MRTMDO"
#>
#> $mrt.md.obs$pptest_cdisc
#> [1] "MRT (for multiple dosing, based on AUCinf,obs)"
#>
#>
#> $mrt.md.pred
#> $mrt.md.pred$FUN
#> [1] "pk.calc.mrt.md"
#>
#> $mrt.md.pred$values
#> [1] FALSE TRUE
#>
#> $mrt.md.pred$unit_type
#> [1] "time"
#>
#> $mrt.md.pred$pretty_name
#> [1] "MRT (for multiple dosing, based on AUCinf,pred)"
#>
#> $mrt.md.pred$desc
#> [1] "MRT, multi-dose AUCinf.pred/AUMCinf.pred"
#>
#> $mrt.md.pred$sparse
#> [1] FALSE
#>
#> $mrt.md.pred$formalsmap
#> $mrt.md.pred$formalsmap$auctau
#> [1] "auclast"
#>
#> $mrt.md.pred$formalsmap$aumctau
#> [1] "aumclast"
#>
#> $mrt.md.pred$formalsmap$aucinf
#> [1] "aucinf.pred"
#>
#>
#> $mrt.md.pred$depends
#> [1] "auclast" "aumclast" "aucinf.pred"
#>
#> $mrt.md.pred$datatype
#> [1] "interval"
#>
#> $mrt.md.pred$pptestcd_cdisc
#> [1] "MRTMDP"
#>
#> $mrt.md.pred$pptest_cdisc
#> [1] "MRT (for multiple dosing, based on AUCinf,pred)"
#>
#>
#> $vz.obs
#> $vz.obs$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.obs$values
#> [1] FALSE TRUE
#>
#> $vz.obs$unit_type
#> [1] "volume"
#>
#> $vz.obs$pretty_name
#> [1] "Vz (based on AUCinf,obs)"
#>
#> $vz.obs$desc
#> [1] "Vz, observed Clast"
#>
#> $vz.obs$sparse
#> [1] FALSE
#>
#> $vz.obs$formalsmap
#> $vz.obs$formalsmap$cl
#> [1] "cl.obs"
#>
#>
#> $vz.obs$depends
#> [1] "cl.obs" "lambda.z"
#>
#> $vz.obs$datatype
#> [1] "interval"
#>
#> $vz.obs$pptestcd_cdisc
#> $vz.obs$pptestcd_cdisc$route
#> $vz.obs$pptestcd_cdisc$route$extravascular
#> [1] "VZF/FO"
#>
#> $vz.obs$pptestcd_cdisc$route$intravascular
#> [1] "VZO"
#>
#>
#>
#> $vz.obs$pptest_cdisc
#> $vz.obs$pptest_cdisc$route
#> $vz.obs$pptest_cdisc$route$extravascular
#> [1] "Vz by F Obs"
#>
#> $vz.obs$pptest_cdisc$route$intravascular
#> [1] "Vz Obs"
#>
#>
#>
#>
#> $vz.pred
#> $vz.pred$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.pred$values
#> [1] FALSE TRUE
#>
#> $vz.pred$unit_type
#> [1] "volume"
#>
#> $vz.pred$pretty_name
#> [1] "Vz (based on AUCinf,pred)"
#>
#> $vz.pred$desc
#> [1] "Vz, predicted Clast"
#>
#> $vz.pred$sparse
#> [1] FALSE
#>
#> $vz.pred$formalsmap
#> $vz.pred$formalsmap$cl
#> [1] "cl.pred"
#>
#>
#> $vz.pred$depends
#> [1] "cl.pred" "lambda.z"
#>
#> $vz.pred$datatype
#> [1] "interval"
#>
#> $vz.pred$pptestcd_cdisc
#> $vz.pred$pptestcd_cdisc$route
#> $vz.pred$pptestcd_cdisc$route$extravascular
#> [1] "VZF/FP"
#>
#> $vz.pred$pptestcd_cdisc$route$intravascular
#> [1] "VZP"
#>
#>
#>
#> $vz.pred$pptest_cdisc
#> $vz.pred$pptest_cdisc$route
#> $vz.pred$pptest_cdisc$route$extravascular
#> [1] "Vz by F Pred"
#>
#> $vz.pred$pptest_cdisc$route$intravascular
#> [1] "Vz Pred"
#>
#>
#>
#>
#> $vz.int.inf.obs
#> $vz.int.inf.obs$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.int.inf.obs$values
#> [1] FALSE TRUE
#>
#> $vz.int.inf.obs$unit_type
#> [1] "volume"
#>
#> $vz.int.inf.obs$pretty_name
#> [1] "Vz (based on AUCint.inf.obs)"
#>
#> $vz.int.inf.obs$desc
#> [1] "Vz, interval AUCint.inf.obs"
#>
#> $vz.int.inf.obs$sparse
#> [1] FALSE
#>
#> $vz.int.inf.obs$formalsmap
#> $vz.int.inf.obs$formalsmap$cl
#> [1] "cl.int.inf.obs"
#>
#>
#> $vz.int.inf.obs$depends
#> [1] "cl.int.inf.obs" "lambda.z"
#>
#> $vz.int.inf.obs$datatype
#> [1] "interval"
#>
#> $vz.int.inf.obs$pptestcd_cdisc
#> [1] "vz.int.inf.obs"
#>
#> $vz.int.inf.obs$pptest_cdisc
#> [1] "Vz, interval AUCint.inf.obs"
#>
#>
#> $vz.int.inf.pred
#> $vz.int.inf.pred$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.int.inf.pred$values
#> [1] FALSE TRUE
#>
#> $vz.int.inf.pred$unit_type
#> [1] "volume"
#>
#> $vz.int.inf.pred$pretty_name
#> [1] "Vz (based on AUCint.inf.pred)"
#>
#> $vz.int.inf.pred$desc
#> [1] "Vz, interval AUCint.inf.pred"
#>
#> $vz.int.inf.pred$sparse
#> [1] FALSE
#>
#> $vz.int.inf.pred$formalsmap
#> $vz.int.inf.pred$formalsmap$cl
#> [1] "cl.int.inf.pred"
#>
#>
#> $vz.int.inf.pred$depends
#> [1] "cl.int.inf.pred" "lambda.z"
#>
#> $vz.int.inf.pred$datatype
#> [1] "interval"
#>
#> $vz.int.inf.pred$pptestcd_cdisc
#> [1] "vz.int.inf.pred"
#>
#> $vz.int.inf.pred$pptest_cdisc
#> [1] "Vz, interval AUCint.inf.pred"
#>
#>
#> $vz.iv.obs
#> $vz.iv.obs$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.iv.obs$values
#> [1] FALSE TRUE
#>
#> $vz.iv.obs$unit_type
#> [1] "volume"
#>
#> $vz.iv.obs$pretty_name
#> [1] "Vz (for IV dosing, based on AUCinf,obs)"
#>
#> $vz.iv.obs$desc
#> [1] "IV Vz, observed AUCinf"
#>
#> $vz.iv.obs$sparse
#> [1] FALSE
#>
#> $vz.iv.obs$formalsmap
#> $vz.iv.obs$formalsmap$cl
#> [1] "cl.iv.obs"
#>
#>
#> $vz.iv.obs$depends
#> [1] "cl.iv.obs" "lambda.z"
#>
#> $vz.iv.obs$datatype
#> [1] "interval"
#>
#> $vz.iv.obs$pptestcd_cdisc
#> [1] "vz.iv.obs"
#>
#> $vz.iv.obs$pptest_cdisc
#> [1] "IV Vz, observed AUCinf"
#>
#>
#> $vz.iv.pred
#> $vz.iv.pred$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.iv.pred$values
#> [1] FALSE TRUE
#>
#> $vz.iv.pred$unit_type
#> [1] "volume"
#>
#> $vz.iv.pred$pretty_name
#> [1] "Vz (for IV dosing, based on AUCinf,pred)"
#>
#> $vz.iv.pred$desc
#> [1] "IV Vz, predicted AUCinf"
#>
#> $vz.iv.pred$sparse
#> [1] FALSE
#>
#> $vz.iv.pred$formalsmap
#> $vz.iv.pred$formalsmap$cl
#> [1] "cl.iv.pred"
#>
#>
#> $vz.iv.pred$depends
#> [1] "cl.iv.pred" "lambda.z"
#>
#> $vz.iv.pred$datatype
#> [1] "interval"
#>
#> $vz.iv.pred$pptestcd_cdisc
#> [1] "vz.iv.pred"
#>
#> $vz.iv.pred$pptest_cdisc
#> [1] "IV Vz, predicted AUCinf"
#>
#>
#> $vz.sparse.last
#> $vz.sparse.last$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.sparse.last$values
#> [1] FALSE TRUE
#>
#> $vz.sparse.last$unit_type
#> [1] "volume"
#>
#> $vz.sparse.last$pretty_name
#> [1] "Vz (for sparse data, based on AUClast)"
#>
#> $vz.sparse.last$desc
#> [1] "Vz from sparse sampling"
#>
#> $vz.sparse.last$sparse
#> [1] TRUE
#>
#> $vz.sparse.last$formalsmap
#> $vz.sparse.last$formalsmap$cl
#> [1] "cl.sparse.last"
#>
#> $vz.sparse.last$formalsmap$lambda.z
#> [1] "kel.sparse.last"
#>
#>
#> $vz.sparse.last$depends
#> [1] "cl.sparse.last" "kel.sparse.last"
#>
#> $vz.sparse.last$datatype
#> [1] "interval"
#>
#> $vz.sparse.last$pptestcd_cdisc
#> [1] "vz.sparse.last"
#>
#> $vz.sparse.last$pptest_cdisc
#> [1] "Vz from sparse sampling"
#>
#>
#> $vss.obs
#> $vss.obs$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.obs$values
#> [1] FALSE TRUE
#>
#> $vss.obs$unit_type
#> [1] "volume"
#>
#> $vss.obs$pretty_name
#> [1] "Vss (based on AUCinf,obs)"
#>
#> $vss.obs$desc
#> [1] "Vss, observed Clast"
#>
#> $vss.obs$sparse
#> [1] FALSE
#>
#> $vss.obs$formalsmap
#> $vss.obs$formalsmap$cl
#> [1] "cl.obs"
#>
#> $vss.obs$formalsmap$mrt
#> [1] "mrt.obs"
#>
#>
#> $vss.obs$depends
#> [1] "cl.obs" "mrt.obs"
#>
#> $vss.obs$datatype
#> [1] "interval"
#>
#> $vss.obs$pptestcd_cdisc
#> $vss.obs$pptestcd_cdisc$route
#> $vss.obs$pptestcd_cdisc$route$extravascular
#> [1] "VSSF/FO"
#>
#> $vss.obs$pptestcd_cdisc$route$intravascular
#> [1] "VSSO"
#>
#>
#>
#> $vss.obs$pptest_cdisc
#> $vss.obs$pptest_cdisc$route
#> $vss.obs$pptest_cdisc$route$extravascular
#> [1] "Vss by F Obs"
#>
#> $vss.obs$pptest_cdisc$route$intravascular
#> [1] "Vol Dist Steady State Obs"
#>
#>
#>
#>
#> $vss.pred
#> $vss.pred$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.pred$values
#> [1] FALSE TRUE
#>
#> $vss.pred$unit_type
#> [1] "volume"
#>
#> $vss.pred$pretty_name
#> [1] "Vss (based on AUCinf,pred)"
#>
#> $vss.pred$desc
#> [1] "Vss, predicted Clast"
#>
#> $vss.pred$sparse
#> [1] FALSE
#>
#> $vss.pred$formalsmap
#> $vss.pred$formalsmap$cl
#> [1] "cl.pred"
#>
#> $vss.pred$formalsmap$mrt
#> [1] "mrt.pred"
#>
#>
#> $vss.pred$depends
#> [1] "cl.pred" "mrt.pred"
#>
#> $vss.pred$datatype
#> [1] "interval"
#>
#> $vss.pred$pptestcd_cdisc
#> $vss.pred$pptestcd_cdisc$route
#> $vss.pred$pptestcd_cdisc$route$extravascular
#> [1] "VSSF/FP"
#>
#> $vss.pred$pptestcd_cdisc$route$intravascular
#> [1] "VSSP"
#>
#>
#>
#> $vss.pred$pptest_cdisc
#> $vss.pred$pptest_cdisc$route
#> $vss.pred$pptest_cdisc$route$extravascular
#> [1] "Vss by F Pred"
#>
#> $vss.pred$pptest_cdisc$route$intravascular
#> [1] "Vol Dist Steady State Pred"
#>
#>
#>
#>
#> $vss.iv.obs
#> $vss.iv.obs$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.iv.obs$values
#> [1] FALSE TRUE
#>
#> $vss.iv.obs$unit_type
#> [1] "volume"
#>
#> $vss.iv.obs$pretty_name
#> [1] "Vss (for IV dosing, based on AUCinf,obs)"
#>
#> $vss.iv.obs$desc
#> [1] "IV Vss, observed Clast"
#>
#> $vss.iv.obs$sparse
#> [1] FALSE
#>
#> $vss.iv.obs$formalsmap
#> $vss.iv.obs$formalsmap$cl
#> [1] "cl.obs"
#>
#> $vss.iv.obs$formalsmap$mrt
#> [1] "mrt.iv.obs"
#>
#>
#> $vss.iv.obs$depends
#> [1] "cl.obs" "mrt.iv.obs"
#>
#> $vss.iv.obs$datatype
#> [1] "interval"
#>
#> $vss.iv.obs$pptestcd_cdisc
#> [1] "VSSIVO"
#>
#> $vss.iv.obs$pptest_cdisc
#> [1] "Vss (for IV dosing, based on AUCinf,obs)"
#>
#>
#> $vss.iv.pred
#> $vss.iv.pred$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.iv.pred$values
#> [1] FALSE TRUE
#>
#> $vss.iv.pred$unit_type
#> [1] "volume"
#>
#> $vss.iv.pred$pretty_name
#> [1] "Vss (for IV dosing, based on AUCinf,pred)"
#>
#> $vss.iv.pred$desc
#> [1] "IV Vss, predicted Clast"
#>
#> $vss.iv.pred$sparse
#> [1] FALSE
#>
#> $vss.iv.pred$formalsmap
#> $vss.iv.pred$formalsmap$cl
#> [1] "cl.pred"
#>
#> $vss.iv.pred$formalsmap$mrt
#> [1] "mrt.iv.pred"
#>
#>
#> $vss.iv.pred$depends
#> [1] "cl.pred" "mrt.iv.pred"
#>
#> $vss.iv.pred$datatype
#> [1] "interval"
#>
#> $vss.iv.pred$pptestcd_cdisc
#> [1] "VSSIVP"
#>
#> $vss.iv.pred$pptest_cdisc
#> [1] "Vss (for IV dosing, based on AUCinf,pred)"
#>
#>
#> $vss.md.obs
#> $vss.md.obs$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.md.obs$values
#> [1] FALSE TRUE
#>
#> $vss.md.obs$unit_type
#> [1] "volume"
#>
#> $vss.md.obs$pretty_name
#> [1] "Vss (for multiple-dose, based on Clast,obs)"
#>
#> $vss.md.obs$desc
#> [1] "Vss, multi-dose, obs"
#>
#> $vss.md.obs$sparse
#> [1] FALSE
#>
#> $vss.md.obs$formalsmap
#> $vss.md.obs$formalsmap$cl
#> [1] "cl.last"
#>
#> $vss.md.obs$formalsmap$mrt
#> [1] "mrt.md.obs"
#>
#>
#> $vss.md.obs$depends
#> [1] "cl.last" "mrt.md.obs"
#>
#> $vss.md.obs$datatype
#> [1] "interval"
#>
#> $vss.md.obs$pptestcd_cdisc
#> [1] "VSSMDO"
#>
#> $vss.md.obs$pptest_cdisc
#> [1] "Vss (for multiple-dose, based on AUCinf,obs)"
#>
#>
#> $vss.md.pred
#> $vss.md.pred$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.md.pred$values
#> [1] FALSE TRUE
#>
#> $vss.md.pred$unit_type
#> [1] "volume"
#>
#> $vss.md.pred$pretty_name
#> [1] "Vss (for multiple-dose, based on Clast,pred)"
#>
#> $vss.md.pred$desc
#> [1] "Vss, multi-dose, pred"
#>
#> $vss.md.pred$sparse
#> [1] FALSE
#>
#> $vss.md.pred$formalsmap
#> $vss.md.pred$formalsmap$cl
#> [1] "cl.last"
#>
#> $vss.md.pred$formalsmap$mrt
#> [1] "mrt.md.pred"
#>
#>
#> $vss.md.pred$depends
#> [1] "cl.last" "mrt.md.pred"
#>
#> $vss.md.pred$datatype
#> [1] "interval"
#>
#> $vss.md.pred$pptestcd_cdisc
#> [1] "VSSMDP"
#>
#> $vss.md.pred$pptest_cdisc
#> [1] "Vss (for multiple-dose, based on AUCinf,pred)"
#>
#>
#> $vss.int.inf.obs
#> $vss.int.inf.obs$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.int.inf.obs$values
#> [1] FALSE TRUE
#>
#> $vss.int.inf.obs$unit_type
#> [1] "volume"
#>
#> $vss.int.inf.obs$pretty_name
#> [1] "Vss (based on AUCint.inf.obs)"
#>
#> $vss.int.inf.obs$desc
#> [1] "Vss, calc from interval AUCint.inf.obs"
#>
#> $vss.int.inf.obs$sparse
#> [1] FALSE
#>
#> $vss.int.inf.obs$formalsmap
#> $vss.int.inf.obs$formalsmap$cl
#> [1] "cl.int.inf.obs"
#>
#> $vss.int.inf.obs$formalsmap$mrt
#> [1] "mrt.int.inf.obs"
#>
#>
#> $vss.int.inf.obs$depends
#> [1] "cl.int.inf.obs" "mrt.int.inf.obs"
#>
#> $vss.int.inf.obs$datatype
#> [1] "interval"
#>
#> $vss.int.inf.obs$pptestcd_cdisc
#> [1] "vss.int.inf.obs"
#>
#> $vss.int.inf.obs$pptest_cdisc
#> [1] "Vss, calc from interval AUCint.inf.obs"
#>
#>
#> $vss.int.inf.pred
#> $vss.int.inf.pred$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.int.inf.pred$values
#> [1] FALSE TRUE
#>
#> $vss.int.inf.pred$unit_type
#> [1] "volume"
#>
#> $vss.int.inf.pred$pretty_name
#> [1] "Vss (based on AUCint.inf.pred)"
#>
#> $vss.int.inf.pred$desc
#> [1] "Vss, calc from interval AUCint.inf.pred"
#>
#> $vss.int.inf.pred$sparse
#> [1] FALSE
#>
#> $vss.int.inf.pred$formalsmap
#> $vss.int.inf.pred$formalsmap$cl
#> [1] "cl.int.inf.pred"
#>
#> $vss.int.inf.pred$formalsmap$mrt
#> [1] "mrt.int.inf.pred"
#>
#>
#> $vss.int.inf.pred$depends
#> [1] "cl.int.inf.pred" "mrt.int.inf.pred"
#>
#> $vss.int.inf.pred$datatype
#> [1] "interval"
#>
#> $vss.int.inf.pred$pptestcd_cdisc
#> [1] "vss.int.inf.pred"
#>
#> $vss.int.inf.pred$pptest_cdisc
#> [1] "Vss, calc from interval AUCint.inf.pred"
#>
#>
#> $cav.int.inf.obs
#> $cav.int.inf.obs$FUN
#> [1] "pk.calc.cav"
#>
#> $cav.int.inf.obs$values
#> [1] FALSE TRUE
#>
#> $cav.int.inf.obs$unit_type
#> [1] "conc"
#>
#> $cav.int.inf.obs$pretty_name
#> [1] "Cav"
#>
#> $cav.int.inf.obs$desc
#> [1] "Avg conc in interval (AUCint.inf.obs)"
#>
#> $cav.int.inf.obs$sparse
#> [1] FALSE
#>
#> $cav.int.inf.obs$formalsmap
#> $cav.int.inf.obs$formalsmap$auc
#> [1] "aucint.inf.obs"
#>
#>
#> $cav.int.inf.obs$depends
#> [1] "aucint.inf.obs"
#>
#> $cav.int.inf.obs$datatype
#> [1] "interval"
#>
#> $cav.int.inf.obs$pptestcd_cdisc
#> [1] "CAVGINO"
#>
#> $cav.int.inf.obs$pptest_cdisc
#> [1] "Cavg Infinity Obs"
#>
#>
#> $cav.int.inf.pred
#> $cav.int.inf.pred$FUN
#> [1] "pk.calc.cav"
#>
#> $cav.int.inf.pred$values
#> [1] FALSE TRUE
#>
#> $cav.int.inf.pred$unit_type
#> [1] "conc"
#>
#> $cav.int.inf.pred$pretty_name
#> [1] "Cav"
#>
#> $cav.int.inf.pred$desc
#> [1] "Avg conc in interval (AUCint.inf.pred)"
#>
#> $cav.int.inf.pred$sparse
#> [1] FALSE
#>
#> $cav.int.inf.pred$formalsmap
#> $cav.int.inf.pred$formalsmap$auc
#> [1] "aucint.inf.pred"
#>
#>
#> $cav.int.inf.pred$depends
#> [1] "aucint.inf.pred"
#>
#> $cav.int.inf.pred$datatype
#> [1] "interval"
#>
#> $cav.int.inf.pred$pptestcd_cdisc
#> [1] "CAVGINP"
#>
#> $cav.int.inf.pred$pptest_cdisc
#> [1] "Cavg Infinity Pred"
#>
#>
#> $thalf.eff.obs
#> $thalf.eff.obs$FUN
#> [1] "pk.calc.thalf.eff"
#>
#> $thalf.eff.obs$values
#> [1] FALSE TRUE
#>
#> $thalf.eff.obs$unit_type
#> [1] "time"
#>
#> $thalf.eff.obs$pretty_name
#> [1] "Effective half-life (based on MRT,obs)"
#>
#> $thalf.eff.obs$desc
#> [1] "Effective half-life, MRTobs"
#>
#> $thalf.eff.obs$sparse
#> [1] FALSE
#>
#> $thalf.eff.obs$formalsmap
#> $thalf.eff.obs$formalsmap$mrt
#> [1] "mrt.obs"
#>
#>
#> $thalf.eff.obs$depends
#> [1] "mrt.obs"
#>
#> $thalf.eff.obs$datatype
#> [1] "interval"
#>
#> $thalf.eff.obs$pptestcd_cdisc
#> [1] "EFFOHL"
#>
#> $thalf.eff.obs$pptest_cdisc
#> [1] "Effective Half-Life Obs"
#>
#>
#> $thalf.eff.pred
#> $thalf.eff.pred$FUN
#> [1] "pk.calc.thalf.eff"
#>
#> $thalf.eff.pred$values
#> [1] FALSE TRUE
#>
#> $thalf.eff.pred$unit_type
#> [1] "time"
#>
#> $thalf.eff.pred$pretty_name
#> [1] "Effective half-life (based on MRT,pred)"
#>
#> $thalf.eff.pred$desc
#> [1] "Effective half-life, MRTpred"
#>
#> $thalf.eff.pred$sparse
#> [1] FALSE
#>
#> $thalf.eff.pred$formalsmap
#> $thalf.eff.pred$formalsmap$mrt
#> [1] "mrt.pred"
#>
#>
#> $thalf.eff.pred$depends
#> [1] "mrt.pred"
#>
#> $thalf.eff.pred$datatype
#> [1] "interval"
#>
#> $thalf.eff.pred$pptestcd_cdisc
#> [1] "EFFPHL"
#>
#> $thalf.eff.pred$pptest_cdisc
#> [1] "Effective Half-Life Pred"
#>
#>
#> $thalf.eff.iv.obs
#> $thalf.eff.iv.obs$FUN
#> [1] "pk.calc.thalf.eff"
#>
#> $thalf.eff.iv.obs$values
#> [1] FALSE TRUE
#>
#> $thalf.eff.iv.obs$unit_type
#> [1] "time"
#>
#> $thalf.eff.iv.obs$pretty_name
#> [1] "Effective half-life (for IV dosing, based on MRT,obs)"
#>
#> $thalf.eff.iv.obs$desc
#> [1] "Effective half-life, IV MRTobs"
#>
#> $thalf.eff.iv.obs$sparse
#> [1] FALSE
#>
#> $thalf.eff.iv.obs$formalsmap
#> $thalf.eff.iv.obs$formalsmap$mrt
#> [1] "mrt.iv.obs"
#>
#>
#> $thalf.eff.iv.obs$depends
#> [1] "mrt.iv.obs"
#>
#> $thalf.eff.iv.obs$datatype
#> [1] "interval"
#>
#> $thalf.eff.iv.obs$pptestcd_cdisc
#> [1] "EFFIVOHL"
#>
#> $thalf.eff.iv.obs$pptest_cdisc
#> [1] "Effective Half-Life (for IV dosing, based on MRT Obs)"
#>
#>
#> $thalf.eff.iv.pred
#> $thalf.eff.iv.pred$FUN
#> [1] "pk.calc.thalf.eff"
#>
#> $thalf.eff.iv.pred$values
#> [1] FALSE TRUE
#>
#> $thalf.eff.iv.pred$unit_type
#> [1] "time"
#>
#> $thalf.eff.iv.pred$pretty_name
#> [1] "Effective half-life (for IV dosing, based on MRT,pred)"
#>
#> $thalf.eff.iv.pred$desc
#> [1] "Effective half-life, IV MRTpred"
#>
#> $thalf.eff.iv.pred$sparse
#> [1] FALSE
#>
#> $thalf.eff.iv.pred$formalsmap
#> $thalf.eff.iv.pred$formalsmap$mrt
#> [1] "mrt.iv.pred"
#>
#>
#> $thalf.eff.iv.pred$depends
#> [1] "mrt.iv.pred"
#>
#> $thalf.eff.iv.pred$datatype
#> [1] "interval"
#>
#> $thalf.eff.iv.pred$pptestcd_cdisc
#> [1] "EFFIVPHL"
#>
#> $thalf.eff.iv.pred$pptest_cdisc
#> [1] "Effective Half-Life (for IV dosing, based on MRT Pred)"
#>
#>
#> $kel.obs
#> $kel.obs$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.obs$values
#> [1] FALSE TRUE
#>
#> $kel.obs$unit_type
#> [1] "inverse_time"
#>
#> $kel.obs$pretty_name
#> [1] "Kel (based on AUCinf,obs)"
#>
#> $kel.obs$desc
#> [1] "Elim rate, MRT w/ obs Clast"
#>
#> $kel.obs$sparse
#> [1] FALSE
#>
#> $kel.obs$formalsmap
#> $kel.obs$formalsmap$mrt
#> [1] "mrt.obs"
#>
#>
#> $kel.obs$depends
#> [1] "mrt.obs"
#>
#> $kel.obs$datatype
#> [1] "interval"
#>
#> $kel.obs$pptestcd_cdisc
#> [1] "KELOS"
#>
#> $kel.obs$pptest_cdisc
#> [1] "Kel (based on AUCinf,obs)"
#>
#>
#> $kel.pred
#> $kel.pred$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.pred$values
#> [1] FALSE TRUE
#>
#> $kel.pred$unit_type
#> [1] "inverse_time"
#>
#> $kel.pred$pretty_name
#> [1] "Kel (based on AUCinf,pred)"
#>
#> $kel.pred$desc
#> [1] "Elim rate, MRT w/ pred Clast"
#>
#> $kel.pred$sparse
#> [1] FALSE
#>
#> $kel.pred$formalsmap
#> $kel.pred$formalsmap$mrt
#> [1] "mrt.pred"
#>
#>
#> $kel.pred$depends
#> [1] "mrt.pred"
#>
#> $kel.pred$datatype
#> [1] "interval"
#>
#> $kel.pred$pptestcd_cdisc
#> [1] "KELP"
#>
#> $kel.pred$pptest_cdisc
#> [1] "Kel (based on AUCinf,pred)"
#>
#>
#> $kel.iv.obs
#> $kel.iv.obs$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.iv.obs$values
#> [1] FALSE TRUE
#>
#> $kel.iv.obs$unit_type
#> [1] "inverse_time"
#>
#> $kel.iv.obs$pretty_name
#> [1] "Kel (for IV dosing, based on AUCinf,obs)"
#>
#> $kel.iv.obs$desc
#> [1] "Elim rate, IV MRTobs"
#>
#> $kel.iv.obs$sparse
#> [1] FALSE
#>
#> $kel.iv.obs$formalsmap
#> $kel.iv.obs$formalsmap$mrt
#> [1] "mrt.iv.obs"
#>
#>
#> $kel.iv.obs$depends
#> [1] "mrt.iv.obs"
#>
#> $kel.iv.obs$datatype
#> [1] "interval"
#>
#> $kel.iv.obs$pptestcd_cdisc
#> [1] "KELIVOS"
#>
#> $kel.iv.obs$pptest_cdisc
#> [1] "Kel (for IV dosing, based on AUCinf,obs)"
#>
#>
#> $kel.iv.pred
#> $kel.iv.pred$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.iv.pred$values
#> [1] FALSE TRUE
#>
#> $kel.iv.pred$unit_type
#> [1] "inverse_time"
#>
#> $kel.iv.pred$pretty_name
#> [1] "Kel (for IV dosing, based on AUCinf,pred)"
#>
#> $kel.iv.pred$desc
#> [1] "Elim rate, IV MRTpred"
#>
#> $kel.iv.pred$sparse
#> [1] FALSE
#>
#> $kel.iv.pred$formalsmap
#> $kel.iv.pred$formalsmap$mrt
#> [1] "mrt.iv.pred"
#>
#>
#> $kel.iv.pred$depends
#> [1] "mrt.iv.pred"
#>
#> $kel.iv.pred$datatype
#> [1] "interval"
#>
#> $kel.iv.pred$pptestcd_cdisc
#> [1] "KELIVP"
#>
#> $kel.iv.pred$pptest_cdisc
#> [1] "Kel (for IV dosing, based on AUCinf,pred)"
#>
#>
#> $kel.int.inf.obs
#> $kel.int.inf.obs$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.int.inf.obs$values
#> [1] FALSE TRUE
#>
#> $kel.int.inf.obs$unit_type
#> [1] "inverse_time"
#>
#> $kel.int.inf.obs$pretty_name
#> [1] "Kel (based on AUCint.inf.obs)"
#>
#> $kel.int.inf.obs$desc
#> [1] "Elim rate, MRTint.inf.obs"
#>
#> $kel.int.inf.obs$sparse
#> [1] FALSE
#>
#> $kel.int.inf.obs$formalsmap
#> $kel.int.inf.obs$formalsmap$mrt
#> [1] "mrt.int.inf.obs"
#>
#>
#> $kel.int.inf.obs$depends
#> [1] "mrt.int.inf.obs"
#>
#> $kel.int.inf.obs$datatype
#> [1] "interval"
#>
#> $kel.int.inf.obs$pptestcd_cdisc
#> [1] "kel.int.inf.obs"
#>
#> $kel.int.inf.obs$pptest_cdisc
#> [1] "Elim rate, MRTint.inf.obs"
#>
#>
#> $kel.int.inf.pred
#> $kel.int.inf.pred$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.int.inf.pred$values
#> [1] FALSE TRUE
#>
#> $kel.int.inf.pred$unit_type
#> [1] "inverse_time"
#>
#> $kel.int.inf.pred$pretty_name
#> [1] "Kel (based on AUCint.inf.pred)"
#>
#> $kel.int.inf.pred$desc
#> [1] "Elim rate, MRTint.inf.pred"
#>
#> $kel.int.inf.pred$sparse
#> [1] FALSE
#>
#> $kel.int.inf.pred$formalsmap
#> $kel.int.inf.pred$formalsmap$mrt
#> [1] "mrt.int.inf.pred"
#>
#>
#> $kel.int.inf.pred$depends
#> [1] "mrt.int.inf.pred"
#>
#> $kel.int.inf.pred$datatype
#> [1] "interval"
#>
#> $kel.int.inf.pred$pptestcd_cdisc
#> [1] "kel.int.inf.pred"
#>
#> $kel.int.inf.pred$pptest_cdisc
#> [1] "Elim rate, MRTint.inf.pred"
#>
#>
#> $auclast.dn
#> $auclast.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $auclast.dn$values
#> [1] FALSE TRUE
#>
#> $auclast.dn$unit_type
#> [1] "auc_dosenorm"
#>
#> $auclast.dn$pretty_name
#> [1] "AUClast (dose-normalized)"
#>
#> $auclast.dn$desc
#> [1] "Dose normalized auclast"
#>
#> $auclast.dn$sparse
#> [1] FALSE
#>
#> $auclast.dn$formalsmap
#> $auclast.dn$formalsmap$parameter
#> [1] "auclast"
#>
#>
#> $auclast.dn$depends
#> [1] "auclast"
#>
#> $auclast.dn$datatype
#> [1] "interval"
#>
#> $auclast.dn$pptestcd_cdisc
#> [1] "AUCLSTD"
#>
#> $auclast.dn$pptest_cdisc
#> [1] "AUC to Last Nonzero Conc by Dose"
#>
#>
#> $aucall.dn
#> $aucall.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $aucall.dn$values
#> [1] FALSE TRUE
#>
#> $aucall.dn$unit_type
#> [1] "auc_dosenorm"
#>
#> $aucall.dn$pretty_name
#> [1] "AUCall (dose-normalized)"
#>
#> $aucall.dn$desc
#> [1] "Dose normalized aucall"
#>
#> $aucall.dn$sparse
#> [1] FALSE
#>
#> $aucall.dn$formalsmap
#> $aucall.dn$formalsmap$parameter
#> [1] "aucall"
#>
#>
#> $aucall.dn$depends
#> [1] "aucall"
#>
#> $aucall.dn$datatype
#> [1] "interval"
#>
#> $aucall.dn$pptestcd_cdisc
#> [1] "AUCALLD"
#>
#> $aucall.dn$pptest_cdisc
#> [1] "AUC All by Dose"
#>
#>
#> $aucinf.obs.dn
#> $aucinf.obs.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $aucinf.obs.dn$values
#> [1] FALSE TRUE
#>
#> $aucinf.obs.dn$unit_type
#> [1] "auc_dosenorm"
#>
#> $aucinf.obs.dn$pretty_name
#> [1] "AUCinf,obs (dose-normalized)"
#>
#> $aucinf.obs.dn$desc
#> [1] "Dose normalized aucinf.obs"
#>
#> $aucinf.obs.dn$sparse
#> [1] FALSE
#>
#> $aucinf.obs.dn$formalsmap
#> $aucinf.obs.dn$formalsmap$parameter
#> [1] "aucinf.obs"
#>
#>
#> $aucinf.obs.dn$depends
#> [1] "aucinf.obs"
#>
#> $aucinf.obs.dn$datatype
#> [1] "interval"
#>
#> $aucinf.obs.dn$pptestcd_cdisc
#> [1] "AUCIFOD"
#>
#> $aucinf.obs.dn$pptest_cdisc
#> [1] "AUC Infinity Obs by Dose"
#>
#>
#> $aucinf.pred.dn
#> $aucinf.pred.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $aucinf.pred.dn$values
#> [1] FALSE TRUE
#>
#> $aucinf.pred.dn$unit_type
#> [1] "auc_dosenorm"
#>
#> $aucinf.pred.dn$pretty_name
#> [1] "AUCinf,pred (dose-normalized)"
#>
#> $aucinf.pred.dn$desc
#> [1] "Dose normalized aucinf.pred"
#>
#> $aucinf.pred.dn$sparse
#> [1] FALSE
#>
#> $aucinf.pred.dn$formalsmap
#> $aucinf.pred.dn$formalsmap$parameter
#> [1] "aucinf.pred"
#>
#>
#> $aucinf.pred.dn$depends
#> [1] "aucinf.pred"
#>
#> $aucinf.pred.dn$datatype
#> [1] "interval"
#>
#> $aucinf.pred.dn$pptestcd_cdisc
#> [1] "AUCIFPD"
#>
#> $aucinf.pred.dn$pptest_cdisc
#> [1] "AUC Infinity Pred by Dose"
#>
#>
#> $aumclast.dn
#> $aumclast.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $aumclast.dn$values
#> [1] FALSE TRUE
#>
#> $aumclast.dn$unit_type
#> [1] "aumc_dosenorm"
#>
#> $aumclast.dn$pretty_name
#> [1] "AUMC,last (dose-normalized)"
#>
#> $aumclast.dn$desc
#> [1] "Dose normalized aumclast"
#>
#> $aumclast.dn$sparse
#> [1] FALSE
#>
#> $aumclast.dn$formalsmap
#> $aumclast.dn$formalsmap$parameter
#> [1] "aumclast"
#>
#>
#> $aumclast.dn$depends
#> [1] "aumclast"
#>
#> $aumclast.dn$datatype
#> [1] "interval"
#>
#> $aumclast.dn$pptestcd_cdisc
#> [1] "AUMCLSTD"
#>
#> $aumclast.dn$pptest_cdisc
#> [1] "AUMC to Last Nonzero Conc by Dose"
#>
#>
#> $aumcall.dn
#> $aumcall.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $aumcall.dn$values
#> [1] FALSE TRUE
#>
#> $aumcall.dn$unit_type
#> [1] "aumc_dosenorm"
#>
#> $aumcall.dn$pretty_name
#> [1] "AUMC,all (dose-normalized)"
#>
#> $aumcall.dn$desc
#> [1] "Dose normalized aumcall"
#>
#> $aumcall.dn$sparse
#> [1] FALSE
#>
#> $aumcall.dn$formalsmap
#> $aumcall.dn$formalsmap$parameter
#> [1] "aumcall"
#>
#>
#> $aumcall.dn$depends
#> [1] "aumcall"
#>
#> $aumcall.dn$datatype
#> [1] "interval"
#>
#> $aumcall.dn$pptestcd_cdisc
#> [1] "AUMCALLD"
#>
#> $aumcall.dn$pptest_cdisc
#> [1] "AUMC All by Dose"
#>
#>
#> $aumcinf.obs.dn
#> $aumcinf.obs.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $aumcinf.obs.dn$values
#> [1] FALSE TRUE
#>
#> $aumcinf.obs.dn$unit_type
#> [1] "aumc_dosenorm"
#>
#> $aumcinf.obs.dn$pretty_name
#> [1] "AUMC,inf,obs (dose-normalized)"
#>
#> $aumcinf.obs.dn$desc
#> [1] "Dose normalized aumcinf.obs"
#>
#> $aumcinf.obs.dn$sparse
#> [1] FALSE
#>
#> $aumcinf.obs.dn$formalsmap
#> $aumcinf.obs.dn$formalsmap$parameter
#> [1] "aumcinf.obs"
#>
#>
#> $aumcinf.obs.dn$depends
#> [1] "aumcinf.obs"
#>
#> $aumcinf.obs.dn$datatype
#> [1] "interval"
#>
#> $aumcinf.obs.dn$pptestcd_cdisc
#> [1] "AUMCIFOD"
#>
#> $aumcinf.obs.dn$pptest_cdisc
#> [1] "AUMC Infinity Obs by Dose"
#>
#>
#> $aumcinf.pred.dn
#> $aumcinf.pred.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $aumcinf.pred.dn$values
#> [1] FALSE TRUE
#>
#> $aumcinf.pred.dn$unit_type
#> [1] "aumc_dosenorm"
#>
#> $aumcinf.pred.dn$pretty_name
#> [1] "AUMC,inf,pred (dose-normalized)"
#>
#> $aumcinf.pred.dn$desc
#> [1] "Dose normalized aumcinf.pred"
#>
#> $aumcinf.pred.dn$sparse
#> [1] FALSE
#>
#> $aumcinf.pred.dn$formalsmap
#> $aumcinf.pred.dn$formalsmap$parameter
#> [1] "aumcinf.pred"
#>
#>
#> $aumcinf.pred.dn$depends
#> [1] "aumcinf.pred"
#>
#> $aumcinf.pred.dn$datatype
#> [1] "interval"
#>
#> $aumcinf.pred.dn$pptestcd_cdisc
#> [1] "AUMCIFPD"
#>
#> $aumcinf.pred.dn$pptest_cdisc
#> [1] "AUMC Infinity Pred by Dose"
#>
#>
#> $cmax.dn
#> $cmax.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $cmax.dn$values
#> [1] FALSE TRUE
#>
#> $cmax.dn$unit_type
#> [1] "conc_dosenorm"
#>
#> $cmax.dn$pretty_name
#> [1] "Cmax (dose-normalized)"
#>
#> $cmax.dn$desc
#> [1] "Dose normalized cmax"
#>
#> $cmax.dn$sparse
#> [1] FALSE
#>
#> $cmax.dn$formalsmap
#> $cmax.dn$formalsmap$parameter
#> [1] "cmax"
#>
#>
#> $cmax.dn$depends
#> [1] "cmax"
#>
#> $cmax.dn$datatype
#> [1] "interval"
#>
#> $cmax.dn$pptestcd_cdisc
#> [1] "CMAXD"
#>
#> $cmax.dn$pptest_cdisc
#> [1] "Max Conc by Dose"
#>
#>
#> $cmin.dn
#> $cmin.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $cmin.dn$values
#> [1] FALSE TRUE
#>
#> $cmin.dn$unit_type
#> [1] "conc_dosenorm"
#>
#> $cmin.dn$pretty_name
#> [1] "Cmin (dose-normalized)"
#>
#> $cmin.dn$desc
#> [1] "Dose normalized cmin"
#>
#> $cmin.dn$sparse
#> [1] FALSE
#>
#> $cmin.dn$formalsmap
#> $cmin.dn$formalsmap$parameter
#> [1] "cmin"
#>
#>
#> $cmin.dn$depends
#> [1] "cmin"
#>
#> $cmin.dn$datatype
#> [1] "interval"
#>
#> $cmin.dn$pptestcd_cdisc
#> [1] "CMIND"
#>
#> $cmin.dn$pptest_cdisc
#> [1] "Min Conc by Dose"
#>
#>
#> $clast.obs.dn
#> $clast.obs.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $clast.obs.dn$values
#> [1] FALSE TRUE
#>
#> $clast.obs.dn$unit_type
#> [1] "conc_dosenorm"
#>
#> $clast.obs.dn$pretty_name
#> [1] "Clast (dose-normalized)"
#>
#> $clast.obs.dn$desc
#> [1] "Dose normalized clast.obs"
#>
#> $clast.obs.dn$sparse
#> [1] FALSE
#>
#> $clast.obs.dn$formalsmap
#> $clast.obs.dn$formalsmap$parameter
#> [1] "clast.obs"
#>
#>
#> $clast.obs.dn$depends
#> [1] "clast.obs"
#>
#> $clast.obs.dn$datatype
#> [1] "interval"
#>
#> $clast.obs.dn$pptestcd_cdisc
#> [1] "CLSTD"
#>
#> $clast.obs.dn$pptest_cdisc
#> [1] "Last Nonzero Conc by Dose"
#>
#>
#> $clast.pred.dn
#> $clast.pred.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $clast.pred.dn$values
#> [1] FALSE TRUE
#>
#> $clast.pred.dn$unit_type
#> [1] "conc_dosenorm"
#>
#> $clast.pred.dn$pretty_name
#> [1] "Clast,pred (dose-normalized)"
#>
#> $clast.pred.dn$desc
#> [1] "Dose normalized clast.pred"
#>
#> $clast.pred.dn$sparse
#> [1] FALSE
#>
#> $clast.pred.dn$formalsmap
#> $clast.pred.dn$formalsmap$parameter
#> [1] "clast.pred"
#>
#>
#> $clast.pred.dn$depends
#> [1] "clast.pred"
#>
#> $clast.pred.dn$datatype
#> [1] "interval"
#>
#> $clast.pred.dn$pptestcd_cdisc
#> [1] "CLSTPD"
#>
#> $clast.pred.dn$pptest_cdisc
#> [1] "Clast pred by Dose"
#>
#>
#> $cav.dn
#> $cav.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $cav.dn$values
#> [1] FALSE TRUE
#>
#> $cav.dn$unit_type
#> [1] "conc_dosenorm"
#>
#> $cav.dn$pretty_name
#> [1] "Cav (dose-normalized)"
#>
#> $cav.dn$desc
#> [1] "Dose normalized cav"
#>
#> $cav.dn$sparse
#> [1] FALSE
#>
#> $cav.dn$formalsmap
#> $cav.dn$formalsmap$parameter
#> [1] "cav"
#>
#>
#> $cav.dn$depends
#> [1] "cav"
#>
#> $cav.dn$datatype
#> [1] "interval"
#>
#> $cav.dn$pptestcd_cdisc
#> [1] "CAVGD"
#>
#> $cav.dn$pptest_cdisc
#> [1] "Average Conc by Dose"
#>
#>
#> $ctrough.dn
#> $ctrough.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $ctrough.dn$values
#> [1] FALSE TRUE
#>
#> $ctrough.dn$unit_type
#> [1] "conc_dosenorm"
#>
#> $ctrough.dn$pretty_name
#> [1] "Ctrough (dose-normalized)"
#>
#> $ctrough.dn$desc
#> [1] "Dose normalized ctrough"
#>
#> $ctrough.dn$sparse
#> [1] FALSE
#>
#> $ctrough.dn$formalsmap
#> $ctrough.dn$formalsmap$parameter
#> [1] "ctrough"
#>
#>
#> $ctrough.dn$depends
#> [1] "ctrough"
#>
#> $ctrough.dn$datatype
#> [1] "interval"
#>
#> $ctrough.dn$pptestcd_cdisc
#> [1] "CTROUGHD"
#>
#> $ctrough.dn$pptest_cdisc
#> [1] "Conc Trough by Dose"
#>
#>
#> $clr.last.dn
#> $clr.last.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $clr.last.dn$values
#> [1] FALSE TRUE
#>
#> $clr.last.dn$unit_type
#> [1] "renal_clearance_dosenorm"
#>
#> $clr.last.dn$pretty_name
#> [1] "Renal clearance (from AUClast) (dose-normalized)"
#>
#> $clr.last.dn$desc
#> [1] "Dose normalized clr.last"
#>
#> $clr.last.dn$sparse
#> [1] FALSE
#>
#> $clr.last.dn$formalsmap
#> $clr.last.dn$formalsmap$parameter
#> [1] "clr.last"
#>
#>
#> $clr.last.dn$depends
#> [1] "clr.last"
#>
#> $clr.last.dn$datatype
#> [1] "interval"
#>
#> $clr.last.dn$pptestcd_cdisc
#> [1] "RENALCLD"
#>
#> $clr.last.dn$pptest_cdisc
#> [1] "Renal CL by Dose"
#>
#>
#> $clr.obs.dn
#> $clr.obs.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $clr.obs.dn$values
#> [1] FALSE TRUE
#>
#> $clr.obs.dn$unit_type
#> [1] "renal_clearance_dosenorm"
#>
#> $clr.obs.dn$pretty_name
#> [1] "Renal clearance (from AUCinf,obs) (dose-normalized)"
#>
#> $clr.obs.dn$desc
#> [1] "Dose normalized clr.obs"
#>
#> $clr.obs.dn$sparse
#> [1] FALSE
#>
#> $clr.obs.dn$formalsmap
#> $clr.obs.dn$formalsmap$parameter
#> [1] "clr.obs"
#>
#>
#> $clr.obs.dn$depends
#> [1] "clr.obs"
#>
#> $clr.obs.dn$datatype
#> [1] "interval"
#>
#> $clr.obs.dn$pptestcd_cdisc
#> [1] "RENALCLD"
#>
#> $clr.obs.dn$pptest_cdisc
#> [1] "Renal CL by Dose"
#>
#>
#> $clr.pred.dn
#> $clr.pred.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $clr.pred.dn$values
#> [1] FALSE TRUE
#>
#> $clr.pred.dn$unit_type
#> [1] "renal_clearance_dosenorm"
#>
#> $clr.pred.dn$pretty_name
#> [1] "Renal clearance (from AUCinf,pred) (dose-normalized)"
#>
#> $clr.pred.dn$desc
#> [1] "Dose normalized clr.pred"
#>
#> $clr.pred.dn$sparse
#> [1] FALSE
#>
#> $clr.pred.dn$formalsmap
#> $clr.pred.dn$formalsmap$parameter
#> [1] "clr.pred"
#>
#>
#> $clr.pred.dn$depends
#> [1] "clr.pred"
#>
#> $clr.pred.dn$datatype
#> [1] "interval"
#>
#> $clr.pred.dn$pptestcd_cdisc
#> [1] "RENALCLD"
#>
#> $clr.pred.dn$pptest_cdisc
#> [1] "Renal CL by Dose"
#>
#>