Check the formatting of a calculation interval specification data frame.

Calculation interval specifications are data frames defining what calculations will be required and summarized from all time intervals. Note: parameters which are not requested may be calculated if it is required for (or computed at the same time as) a requested parameter.

Usage

check.interval.specification(x)

Arguments

x

The data frame specifying what to calculate during each time interval

Value

x The potentially updated data frame with the interval calculation specification.

Details

start and end time must always be given as columns, and the start must be before the end. Other columns define the parameters to be calculated and the groupings to apply the intervals to.

Data are selected for calculation within an interval by the time of the measurement or dose: a row is included when its time is at or after start and at or before end (a dose exactly at end is not included in the interval). For duration data (for example, urine collections or intravenous infusions), the time is the start of the collection or administration, and the duration is not considered during selection: a collection that starts within the interval and ends after end is included and contributes its full amount to the interval. For the simplest interpretation of results, align collection start and end times with interval boundaries.

See also

The vignette "Selection of Calculation Intervals"

Other Interval specifications: add.interval.col(), choose.auc.intervals(), get.interval.cols(), get.parameter.deps()