This data.frame is typically used for the units argument for PKNCAdata().
If a unit is not given, then all of the units derived from that unit will be
NA.
Usage
pknca_units_table(
concu,
doseu,
amountu,
timeu,
concu_pref = NULL,
doseu_pref = NULL,
amountu_pref = NULL,
timeu_pref = NULL,
conversions = data.frame()
)Arguments
- concu, doseu, amountu, timeu
Units for concentration, dose, amount, and time in the source data
- concu_pref, doseu_pref, amountu_pref, timeu_pref
Preferred units for reporting;
conversionswill be automatically.- conversions
An optional data.frame with columns of c("PPORRESU", "PPSTRESU", "conversion_factor") for the original calculation units, the standardized units, and a conversion factor to multiply the initial value by to get a standardized value. This argument overrides any preferred unit conversions from
concu_pref,doseu_pref,amountu_pref, ortimeu_pref.
Value
A unit conversion table with columns for "PPTESTCD" and "PPORRESU"
if conversions is not given, and adding "PPSTRESU" and
"conversion_factor" if conversions is given.
See also
The units argument for PKNCAdata()
Examples
pknca_units_table() # only parameters that are unitless
#> PPORRESU PPTESTCD
#> 1 unitless r.squared
#> 2 unitless adj.r.squared
#> 3 unitless lambda.z.corrxy
#> 4 fraction f
#> 5 fraction ptr
#> 6 fraction span.ratio
#> 7 % deg.fluc
#> 8 % swing
#> 9 % aucivpbextlast
#> 10 % aucivpbextall
#> 11 % aucivpbextint.last
#> 12 % aucivpbextint.all
#> 13 % aucivpbextinf.obs
#> 14 % aucivpbextinf.pred
#> 15 % aucpext.obs
#> 16 % aucpext.pred
#> 17 count count_conc
#> 18 count count_conc_measured
#> 19 count sparse_auc_df
#> 20 count lambda.z.n.points
#> 21 <NA> start
#> 22 <NA> end
#> 23 <NA> tmax
#> 24 <NA> tlast
#> 25 <NA> tfirst
#> 26 <NA> mrt.last
#> 27 <NA> mrt.iv.last
#> 28 <NA> tlag
#> 29 <NA> ertlst
#> 30 <NA> ertmax
#> 31 <NA> time_above
#> 32 <NA> half.life
#> 33 <NA> lambda.z.time.first
#> 34 <NA> lambda.z.time.last
#> 35 <NA> thalf.eff.last
#> 36 <NA> thalf.eff.iv.last
#> 37 <NA> mrt.obs
#> 38 <NA> mrt.pred
#> 39 <NA> mrt.iv.obs
#> 40 <NA> mrt.iv.pred
#> 41 <NA> mrt.md.obs
#> 42 <NA> mrt.md.pred
#> 43 <NA> thalf.eff.obs
#> 44 <NA> thalf.eff.pred
#> 45 <NA> thalf.eff.iv.obs
#> 46 <NA> thalf.eff.iv.pred
#> 47 <NA> lambda.z
#> 48 <NA> kel.last
#> 49 <NA> kel.iv.last
#> 50 <NA> kel.obs
#> 51 <NA> kel.pred
#> 52 <NA> kel.iv.obs
#> 53 <NA> kel.iv.pred
#> 54 <NA> c0
#> 55 <NA> cmax
#> 56 <NA> cmin
#> 57 <NA> clast.obs
#> 58 <NA> cav
#> 59 <NA> cav.int.last
#> 60 <NA> cav.int.all
#> 61 <NA> ctrough
#> 62 <NA> cstart
#> 63 <NA> ceoi
#> 64 <NA> clast.pred
#> 65 <NA> cav.int.inf.obs
#> 66 <NA> cav.int.inf.pred
#> 67 <NA> ae
#> 68 <NA> fe
#> 69 <NA> totdose
#> 70 <NA> cmax.dn
#> 71 <NA> cmin.dn
#> 72 <NA> clast.obs.dn
#> 73 <NA> clast.pred.dn
#> 74 <NA> cav.dn
#> 75 <NA> ctrough.dn
#> 76 <NA> vss.last
#> 77 <NA> vss.iv.last
#> 78 <NA> volpk
#> 79 <NA> vz.obs
#> 80 <NA> vz.pred
#> 81 <NA> vss.obs
#> 82 <NA> vss.pred
#> 83 <NA> vss.iv.obs
#> 84 <NA> vss.iv.pred
#> 85 <NA> vss.md.obs
#> 86 <NA> vss.md.pred
#> 87 <NA> auclast
#> 88 <NA> aucall
#> 89 <NA> aucint.last
#> 90 <NA> aucint.last.dose
#> 91 <NA> aucint.all
#> 92 <NA> aucint.all.dose
#> 93 <NA> aucabove.predose.all
#> 94 <NA> aucabove.trough.all
#> 95 <NA> sparse_auclast
#> 96 <NA> sparse_auc_se
#> 97 <NA> aucivlast
#> 98 <NA> aucivall
#> 99 <NA> aucivint.last
#> 100 <NA> aucivint.all
#> 101 <NA> aucinf.obs
#> 102 <NA> aucinf.pred
#> 103 <NA> aucint.inf.obs
#> 104 <NA> aucint.inf.obs.dose
#> 105 <NA> aucint.inf.pred
#> 106 <NA> aucint.inf.pred.dose
#> 107 <NA> aucivinf.obs
#> 108 <NA> aucivinf.pred
#> 109 <NA> aumclast
#> 110 <NA> aumcall
#> 111 <NA> aumcinf.obs
#> 112 <NA> aumcinf.pred
#> 113 <NA> ermax
#> 114 <NA> auclast.dn
#> 115 <NA> aucall.dn
#> 116 <NA> aucinf.obs.dn
#> 117 <NA> aucinf.pred.dn
#> 118 <NA> aumclast.dn
#> 119 <NA> aumcall.dn
#> 120 <NA> aumcinf.obs.dn
#> 121 <NA> aumcinf.pred.dn
#> 122 <NA> cl.last
#> 123 <NA> cl.all
#> 124 <NA> cl.obs
#> 125 <NA> cl.pred
#> 126 <NA> clr.last
#> 127 <NA> clr.obs
#> 128 <NA> clr.pred
#> 129 <NA> clr.last.dn
#> 130 <NA> clr.obs.dn
#> 131 <NA> clr.pred.dn
pknca_units_table(
concu="ng/mL", doseu="mg/kg", amountu="mg", timeu="hr"
)
#> PPORRESU PPTESTCD
#> 1 unitless r.squared
#> 2 unitless adj.r.squared
#> 3 unitless lambda.z.corrxy
#> 4 fraction f
#> 5 fraction ptr
#> 6 fraction span.ratio
#> 7 % deg.fluc
#> 8 % swing
#> 9 % aucivpbextlast
#> 10 % aucivpbextall
#> 11 % aucivpbextint.last
#> 12 % aucivpbextint.all
#> 13 % aucivpbextinf.obs
#> 14 % aucivpbextinf.pred
#> 15 % aucpext.obs
#> 16 % aucpext.pred
#> 17 count count_conc
#> 18 count count_conc_measured
#> 19 count sparse_auc_df
#> 20 count lambda.z.n.points
#> 21 hr start
#> 22 hr end
#> 23 hr tmax
#> 24 hr tlast
#> 25 hr tfirst
#> 26 hr mrt.last
#> 27 hr mrt.iv.last
#> 28 hr tlag
#> 29 hr ertlst
#> 30 hr ertmax
#> 31 hr time_above
#> 32 hr half.life
#> 33 hr lambda.z.time.first
#> 34 hr lambda.z.time.last
#> 35 hr thalf.eff.last
#> 36 hr thalf.eff.iv.last
#> 37 hr mrt.obs
#> 38 hr mrt.pred
#> 39 hr mrt.iv.obs
#> 40 hr mrt.iv.pred
#> 41 hr mrt.md.obs
#> 42 hr mrt.md.pred
#> 43 hr thalf.eff.obs
#> 44 hr thalf.eff.pred
#> 45 hr thalf.eff.iv.obs
#> 46 hr thalf.eff.iv.pred
#> 47 1/hr lambda.z
#> 48 1/hr kel.last
#> 49 1/hr kel.iv.last
#> 50 1/hr kel.obs
#> 51 1/hr kel.pred
#> 52 1/hr kel.iv.obs
#> 53 1/hr kel.iv.pred
#> 54 ng/mL c0
#> 55 ng/mL cmax
#> 56 ng/mL cmin
#> 57 ng/mL clast.obs
#> 58 ng/mL cav
#> 59 ng/mL cav.int.last
#> 60 ng/mL cav.int.all
#> 61 ng/mL ctrough
#> 62 ng/mL cstart
#> 63 ng/mL ceoi
#> 64 ng/mL clast.pred
#> 65 ng/mL cav.int.inf.obs
#> 66 ng/mL cav.int.inf.pred
#> 67 mg ae
#> 68 mg/(mg/kg) fe
#> 69 mg/kg totdose
#> 70 (ng/mL)/(mg/kg) cmax.dn
#> 71 (ng/mL)/(mg/kg) cmin.dn
#> 72 (ng/mL)/(mg/kg) clast.obs.dn
#> 73 (ng/mL)/(mg/kg) clast.pred.dn
#> 74 (ng/mL)/(mg/kg) cav.dn
#> 75 (ng/mL)/(mg/kg) ctrough.dn
#> 76 (mg/kg)/(ng/mL) vss.last
#> 77 (mg/kg)/(ng/mL) vss.iv.last
#> 78 (mg/kg)/(ng/mL) volpk
#> 79 (mg/kg)/(ng/mL) vz.obs
#> 80 (mg/kg)/(ng/mL) vz.pred
#> 81 (mg/kg)/(ng/mL) vss.obs
#> 82 (mg/kg)/(ng/mL) vss.pred
#> 83 (mg/kg)/(ng/mL) vss.iv.obs
#> 84 (mg/kg)/(ng/mL) vss.iv.pred
#> 85 (mg/kg)/(ng/mL) vss.md.obs
#> 86 (mg/kg)/(ng/mL) vss.md.pred
#> 87 hr*ng/mL auclast
#> 88 hr*ng/mL aucall
#> 89 hr*ng/mL aucint.last
#> 90 hr*ng/mL aucint.last.dose
#> 91 hr*ng/mL aucint.all
#> 92 hr*ng/mL aucint.all.dose
#> 93 hr*ng/mL aucabove.predose.all
#> 94 hr*ng/mL aucabove.trough.all
#> 95 hr*ng/mL sparse_auclast
#> 96 hr*ng/mL sparse_auc_se
#> 97 hr*ng/mL aucivlast
#> 98 hr*ng/mL aucivall
#> 99 hr*ng/mL aucivint.last
#> 100 hr*ng/mL aucivint.all
#> 101 hr*ng/mL aucinf.obs
#> 102 hr*ng/mL aucinf.pred
#> 103 hr*ng/mL aucint.inf.obs
#> 104 hr*ng/mL aucint.inf.obs.dose
#> 105 hr*ng/mL aucint.inf.pred
#> 106 hr*ng/mL aucint.inf.pred.dose
#> 107 hr*ng/mL aucivinf.obs
#> 108 hr*ng/mL aucivinf.pred
#> 109 hr^2*ng/mL aumclast
#> 110 hr^2*ng/mL aumcall
#> 111 hr^2*ng/mL aumcinf.obs
#> 112 hr^2*ng/mL aumcinf.pred
#> 113 hr*mg ermax
#> 114 (hr*ng/mL)/(mg/kg) auclast.dn
#> 115 (hr*ng/mL)/(mg/kg) aucall.dn
#> 116 (hr*ng/mL)/(mg/kg) aucinf.obs.dn
#> 117 (hr*ng/mL)/(mg/kg) aucinf.pred.dn
#> 118 (hr^2*ng/mL)/(mg/kg) aumclast.dn
#> 119 (hr^2*ng/mL)/(mg/kg) aumcall.dn
#> 120 (hr^2*ng/mL)/(mg/kg) aumcinf.obs.dn
#> 121 (hr^2*ng/mL)/(mg/kg) aumcinf.pred.dn
#> 122 (mg/kg)/(hr*ng/mL) cl.last
#> 123 (mg/kg)/(hr*ng/mL) cl.all
#> 124 (mg/kg)/(hr*ng/mL) cl.obs
#> 125 (mg/kg)/(hr*ng/mL) cl.pred
#> 126 mg/(hr*ng/mL) clr.last
#> 127 mg/(hr*ng/mL) clr.obs
#> 128 mg/(hr*ng/mL) clr.pred
#> 129 (mg/(hr*ng/mL))/(mg/kg) clr.last.dn
#> 130 (mg/(hr*ng/mL))/(mg/kg) clr.obs.dn
#> 131 (mg/(hr*ng/mL))/(mg/kg) clr.pred.dn
pknca_units_table(
concu="ng/mL", doseu="mg/kg", amountu="mg", timeu="hr",
# Convert clearance and volume units to more understandable units with
# automatic unit conversion
conversions=data.frame(
PPORRESU=c("(mg/kg)/(hr*ng/mL)", "(mg/kg)/(ng/mL)"),
PPSTRESU=c("mL/hr/kg", "mL/kg")
)
)
#> PPORRESU PPTESTCD PPSTRESU
#> 1 unitless r.squared unitless
#> 2 unitless adj.r.squared unitless
#> 3 unitless lambda.z.corrxy unitless
#> 4 fraction f fraction
#> 5 fraction ptr fraction
#> 6 fraction span.ratio fraction
#> 7 % deg.fluc %
#> 8 % swing %
#> 9 % aucivpbextlast %
#> 10 % aucivpbextall %
#> 11 % aucivpbextint.last %
#> 12 % aucivpbextint.all %
#> 13 % aucivpbextinf.obs %
#> 14 % aucivpbextinf.pred %
#> 15 % aucpext.obs %
#> 16 % aucpext.pred %
#> 17 count count_conc count
#> 18 count count_conc_measured count
#> 19 count sparse_auc_df count
#> 20 count lambda.z.n.points count
#> 21 hr start hr
#> 22 hr end hr
#> 23 hr tmax hr
#> 24 hr tlast hr
#> 25 hr tfirst hr
#> 26 hr mrt.last hr
#> 27 hr mrt.iv.last hr
#> 28 hr tlag hr
#> 29 hr ertlst hr
#> 30 hr ertmax hr
#> 31 hr time_above hr
#> 32 hr half.life hr
#> 33 hr lambda.z.time.first hr
#> 34 hr lambda.z.time.last hr
#> 35 hr thalf.eff.last hr
#> 36 hr thalf.eff.iv.last hr
#> 37 hr mrt.obs hr
#> 38 hr mrt.pred hr
#> 39 hr mrt.iv.obs hr
#> 40 hr mrt.iv.pred hr
#> 41 hr mrt.md.obs hr
#> 42 hr mrt.md.pred hr
#> 43 hr thalf.eff.obs hr
#> 44 hr thalf.eff.pred hr
#> 45 hr thalf.eff.iv.obs hr
#> 46 hr thalf.eff.iv.pred hr
#> 47 1/hr lambda.z 1/hr
#> 48 1/hr kel.last 1/hr
#> 49 1/hr kel.iv.last 1/hr
#> 50 1/hr kel.obs 1/hr
#> 51 1/hr kel.pred 1/hr
#> 52 1/hr kel.iv.obs 1/hr
#> 53 1/hr kel.iv.pred 1/hr
#> 54 ng/mL c0 ng/mL
#> 55 ng/mL cmax ng/mL
#> 56 ng/mL cmin ng/mL
#> 57 ng/mL clast.obs ng/mL
#> 58 ng/mL cav ng/mL
#> 59 ng/mL cav.int.last ng/mL
#> 60 ng/mL cav.int.all ng/mL
#> 61 ng/mL ctrough ng/mL
#> 62 ng/mL cstart ng/mL
#> 63 ng/mL ceoi ng/mL
#> 64 ng/mL clast.pred ng/mL
#> 65 ng/mL cav.int.inf.obs ng/mL
#> 66 ng/mL cav.int.inf.pred ng/mL
#> 67 mg ae mg
#> 68 mg/(mg/kg) fe mg/(mg/kg)
#> 69 mg/kg totdose mg/kg
#> 70 (ng/mL)/(mg/kg) cmax.dn (ng/mL)/(mg/kg)
#> 71 (ng/mL)/(mg/kg) cmin.dn (ng/mL)/(mg/kg)
#> 72 (ng/mL)/(mg/kg) clast.obs.dn (ng/mL)/(mg/kg)
#> 73 (ng/mL)/(mg/kg) clast.pred.dn (ng/mL)/(mg/kg)
#> 74 (ng/mL)/(mg/kg) cav.dn (ng/mL)/(mg/kg)
#> 75 (ng/mL)/(mg/kg) ctrough.dn (ng/mL)/(mg/kg)
#> 76 (mg/kg)/(ng/mL) vss.last mL/kg
#> 77 (mg/kg)/(ng/mL) vss.iv.last mL/kg
#> 78 (mg/kg)/(ng/mL) volpk mL/kg
#> 79 (mg/kg)/(ng/mL) vz.obs mL/kg
#> 80 (mg/kg)/(ng/mL) vz.pred mL/kg
#> 81 (mg/kg)/(ng/mL) vss.obs mL/kg
#> 82 (mg/kg)/(ng/mL) vss.pred mL/kg
#> 83 (mg/kg)/(ng/mL) vss.iv.obs mL/kg
#> 84 (mg/kg)/(ng/mL) vss.iv.pred mL/kg
#> 85 (mg/kg)/(ng/mL) vss.md.obs mL/kg
#> 86 (mg/kg)/(ng/mL) vss.md.pred mL/kg
#> 87 hr*ng/mL auclast hr*ng/mL
#> 88 hr*ng/mL aucall hr*ng/mL
#> 89 hr*ng/mL aucint.last hr*ng/mL
#> 90 hr*ng/mL aucint.last.dose hr*ng/mL
#> 91 hr*ng/mL aucint.all hr*ng/mL
#> 92 hr*ng/mL aucint.all.dose hr*ng/mL
#> 93 hr*ng/mL aucabove.predose.all hr*ng/mL
#> 94 hr*ng/mL aucabove.trough.all hr*ng/mL
#> 95 hr*ng/mL sparse_auclast hr*ng/mL
#> 96 hr*ng/mL sparse_auc_se hr*ng/mL
#> 97 hr*ng/mL aucivlast hr*ng/mL
#> 98 hr*ng/mL aucivall hr*ng/mL
#> 99 hr*ng/mL aucivint.last hr*ng/mL
#> 100 hr*ng/mL aucivint.all hr*ng/mL
#> 101 hr*ng/mL aucinf.obs hr*ng/mL
#> 102 hr*ng/mL aucinf.pred hr*ng/mL
#> 103 hr*ng/mL aucint.inf.obs hr*ng/mL
#> 104 hr*ng/mL aucint.inf.obs.dose hr*ng/mL
#> 105 hr*ng/mL aucint.inf.pred hr*ng/mL
#> 106 hr*ng/mL aucint.inf.pred.dose hr*ng/mL
#> 107 hr*ng/mL aucivinf.obs hr*ng/mL
#> 108 hr*ng/mL aucivinf.pred hr*ng/mL
#> 109 hr^2*ng/mL aumclast hr^2*ng/mL
#> 110 hr^2*ng/mL aumcall hr^2*ng/mL
#> 111 hr^2*ng/mL aumcinf.obs hr^2*ng/mL
#> 112 hr^2*ng/mL aumcinf.pred hr^2*ng/mL
#> 113 hr*mg ermax hr*mg
#> 114 (hr*ng/mL)/(mg/kg) auclast.dn (hr*ng/mL)/(mg/kg)
#> 115 (hr*ng/mL)/(mg/kg) aucall.dn (hr*ng/mL)/(mg/kg)
#> 116 (hr*ng/mL)/(mg/kg) aucinf.obs.dn (hr*ng/mL)/(mg/kg)
#> 117 (hr*ng/mL)/(mg/kg) aucinf.pred.dn (hr*ng/mL)/(mg/kg)
#> 118 (hr^2*ng/mL)/(mg/kg) aumclast.dn (hr^2*ng/mL)/(mg/kg)
#> 119 (hr^2*ng/mL)/(mg/kg) aumcall.dn (hr^2*ng/mL)/(mg/kg)
#> 120 (hr^2*ng/mL)/(mg/kg) aumcinf.obs.dn (hr^2*ng/mL)/(mg/kg)
#> 121 (hr^2*ng/mL)/(mg/kg) aumcinf.pred.dn (hr^2*ng/mL)/(mg/kg)
#> 122 (mg/kg)/(hr*ng/mL) cl.last mL/hr/kg
#> 123 (mg/kg)/(hr*ng/mL) cl.all mL/hr/kg
#> 124 (mg/kg)/(hr*ng/mL) cl.obs mL/hr/kg
#> 125 (mg/kg)/(hr*ng/mL) cl.pred mL/hr/kg
#> 126 mg/(hr*ng/mL) clr.last mg/(hr*ng/mL)
#> 127 mg/(hr*ng/mL) clr.obs mg/(hr*ng/mL)
#> 128 mg/(hr*ng/mL) clr.pred mg/(hr*ng/mL)
#> 129 (mg/(hr*ng/mL))/(mg/kg) clr.last.dn (mg/(hr*ng/mL))/(mg/kg)
#> 130 (mg/(hr*ng/mL))/(mg/kg) clr.obs.dn (mg/(hr*ng/mL))/(mg/kg)
#> 131 (mg/(hr*ng/mL))/(mg/kg) clr.pred.dn (mg/(hr*ng/mL))/(mg/kg)
#> conversion_factor
#> 1 1e+00
#> 2 1e+00
#> 3 1e+00
#> 4 1e+00
#> 5 1e+00
#> 6 1e+00
#> 7 1e+00
#> 8 1e+00
#> 9 1e+00
#> 10 1e+00
#> 11 1e+00
#> 12 1e+00
#> 13 1e+00
#> 14 1e+00
#> 15 1e+00
#> 16 1e+00
#> 17 1e+00
#> 18 1e+00
#> 19 1e+00
#> 20 1e+00
#> 21 1e+00
#> 22 1e+00
#> 23 1e+00
#> 24 1e+00
#> 25 1e+00
#> 26 1e+00
#> 27 1e+00
#> 28 1e+00
#> 29 1e+00
#> 30 1e+00
#> 31 1e+00
#> 32 1e+00
#> 33 1e+00
#> 34 1e+00
#> 35 1e+00
#> 36 1e+00
#> 37 1e+00
#> 38 1e+00
#> 39 1e+00
#> 40 1e+00
#> 41 1e+00
#> 42 1e+00
#> 43 1e+00
#> 44 1e+00
#> 45 1e+00
#> 46 1e+00
#> 47 1e+00
#> 48 1e+00
#> 49 1e+00
#> 50 1e+00
#> 51 1e+00
#> 52 1e+00
#> 53 1e+00
#> 54 1e+00
#> 55 1e+00
#> 56 1e+00
#> 57 1e+00
#> 58 1e+00
#> 59 1e+00
#> 60 1e+00
#> 61 1e+00
#> 62 1e+00
#> 63 1e+00
#> 64 1e+00
#> 65 1e+00
#> 66 1e+00
#> 67 1e+00
#> 68 1e+00
#> 69 1e+00
#> 70 1e+00
#> 71 1e+00
#> 72 1e+00
#> 73 1e+00
#> 74 1e+00
#> 75 1e+00
#> 76 1e+06
#> 77 1e+06
#> 78 1e+06
#> 79 1e+06
#> 80 1e+06
#> 81 1e+06
#> 82 1e+06
#> 83 1e+06
#> 84 1e+06
#> 85 1e+06
#> 86 1e+06
#> 87 1e+00
#> 88 1e+00
#> 89 1e+00
#> 90 1e+00
#> 91 1e+00
#> 92 1e+00
#> 93 1e+00
#> 94 1e+00
#> 95 1e+00
#> 96 1e+00
#> 97 1e+00
#> 98 1e+00
#> 99 1e+00
#> 100 1e+00
#> 101 1e+00
#> 102 1e+00
#> 103 1e+00
#> 104 1e+00
#> 105 1e+00
#> 106 1e+00
#> 107 1e+00
#> 108 1e+00
#> 109 1e+00
#> 110 1e+00
#> 111 1e+00
#> 112 1e+00
#> 113 1e+00
#> 114 1e+00
#> 115 1e+00
#> 116 1e+00
#> 117 1e+00
#> 118 1e+00
#> 119 1e+00
#> 120 1e+00
#> 121 1e+00
#> 122 1e+06
#> 123 1e+06
#> 124 1e+06
#> 125 1e+06
#> 126 1e+00
#> 127 1e+00
#> 128 1e+00
#> 129 1e+00
#> 130 1e+00
#> 131 1e+00
pknca_units_table(
concu="mg/L", doseu="mg/kg", amountu="mg", timeu="hr",
# Convert clearance and volume units to molar units (assuming
conversions=data.frame(
PPORRESU=c("mg/L", "(mg/kg)/(hr*ng/mL)", "(mg/kg)/(ng/mL)"),
PPSTRESU=c("mmol/L", "mL/hr/kg", "mL/kg"),
# Manual conversion of concentration units from ng/mL to mmol/L (assuming
# a molecular weight of 138.121 g/mol)
conversion_factor=c(1/138.121, NA, NA)
)
)
#> Warning: The following unit conversions were supplied but do not match any units to convert: '(mg/kg)/(hr*ng/mL)', '(mg/kg)/(ng/mL)'
#> PPORRESU PPTESTCD PPSTRESU
#> 1 unitless r.squared unitless
#> 2 unitless adj.r.squared unitless
#> 3 unitless lambda.z.corrxy unitless
#> 4 fraction f fraction
#> 5 fraction ptr fraction
#> 6 fraction span.ratio fraction
#> 7 % deg.fluc %
#> 8 % swing %
#> 9 % aucivpbextlast %
#> 10 % aucivpbextall %
#> 11 % aucivpbextint.last %
#> 12 % aucivpbextint.all %
#> 13 % aucivpbextinf.obs %
#> 14 % aucivpbextinf.pred %
#> 15 % aucpext.obs %
#> 16 % aucpext.pred %
#> 17 count count_conc count
#> 18 count count_conc_measured count
#> 19 count sparse_auc_df count
#> 20 count lambda.z.n.points count
#> 21 hr start hr
#> 22 hr end hr
#> 23 hr tmax hr
#> 24 hr tlast hr
#> 25 hr tfirst hr
#> 26 hr mrt.last hr
#> 27 hr mrt.iv.last hr
#> 28 hr tlag hr
#> 29 hr ertlst hr
#> 30 hr ertmax hr
#> 31 hr time_above hr
#> 32 hr half.life hr
#> 33 hr lambda.z.time.first hr
#> 34 hr lambda.z.time.last hr
#> 35 hr thalf.eff.last hr
#> 36 hr thalf.eff.iv.last hr
#> 37 hr mrt.obs hr
#> 38 hr mrt.pred hr
#> 39 hr mrt.iv.obs hr
#> 40 hr mrt.iv.pred hr
#> 41 hr mrt.md.obs hr
#> 42 hr mrt.md.pred hr
#> 43 hr thalf.eff.obs hr
#> 44 hr thalf.eff.pred hr
#> 45 hr thalf.eff.iv.obs hr
#> 46 hr thalf.eff.iv.pred hr
#> 47 1/hr lambda.z 1/hr
#> 48 1/hr kel.last 1/hr
#> 49 1/hr kel.iv.last 1/hr
#> 50 1/hr kel.obs 1/hr
#> 51 1/hr kel.pred 1/hr
#> 52 1/hr kel.iv.obs 1/hr
#> 53 1/hr kel.iv.pred 1/hr
#> 54 mg/L c0 mmol/L
#> 55 mg/L cmax mmol/L
#> 56 mg/L cmin mmol/L
#> 57 mg/L clast.obs mmol/L
#> 58 mg/L cav mmol/L
#> 59 mg/L cav.int.last mmol/L
#> 60 mg/L cav.int.all mmol/L
#> 61 mg/L ctrough mmol/L
#> 62 mg/L cstart mmol/L
#> 63 mg/L ceoi mmol/L
#> 64 mg/L clast.pred mmol/L
#> 65 mg/L cav.int.inf.obs mmol/L
#> 66 mg/L cav.int.inf.pred mmol/L
#> 67 mg ae mg
#> 68 mg/(mg/kg) fe mg/(mg/kg)
#> 69 mg/kg totdose mg/kg
#> 70 (mg/L)/(mg/kg) cmax.dn (mg/L)/(mg/kg)
#> 71 (mg/L)/(mg/kg) cmin.dn (mg/L)/(mg/kg)
#> 72 (mg/L)/(mg/kg) clast.obs.dn (mg/L)/(mg/kg)
#> 73 (mg/L)/(mg/kg) clast.pred.dn (mg/L)/(mg/kg)
#> 74 (mg/L)/(mg/kg) cav.dn (mg/L)/(mg/kg)
#> 75 (mg/L)/(mg/kg) ctrough.dn (mg/L)/(mg/kg)
#> 76 (mg/kg)/(mg/L) vss.last (mg/kg)/(mg/L)
#> 77 (mg/kg)/(mg/L) vss.iv.last (mg/kg)/(mg/L)
#> 78 (mg/kg)/(mg/L) volpk (mg/kg)/(mg/L)
#> 79 (mg/kg)/(mg/L) vz.obs (mg/kg)/(mg/L)
#> 80 (mg/kg)/(mg/L) vz.pred (mg/kg)/(mg/L)
#> 81 (mg/kg)/(mg/L) vss.obs (mg/kg)/(mg/L)
#> 82 (mg/kg)/(mg/L) vss.pred (mg/kg)/(mg/L)
#> 83 (mg/kg)/(mg/L) vss.iv.obs (mg/kg)/(mg/L)
#> 84 (mg/kg)/(mg/L) vss.iv.pred (mg/kg)/(mg/L)
#> 85 (mg/kg)/(mg/L) vss.md.obs (mg/kg)/(mg/L)
#> 86 (mg/kg)/(mg/L) vss.md.pred (mg/kg)/(mg/L)
#> 87 hr*mg/L auclast hr*mg/L
#> 88 hr*mg/L aucall hr*mg/L
#> 89 hr*mg/L aucint.last hr*mg/L
#> 90 hr*mg/L aucint.last.dose hr*mg/L
#> 91 hr*mg/L aucint.all hr*mg/L
#> 92 hr*mg/L aucint.all.dose hr*mg/L
#> 93 hr*mg/L aucabove.predose.all hr*mg/L
#> 94 hr*mg/L aucabove.trough.all hr*mg/L
#> 95 hr*mg/L sparse_auclast hr*mg/L
#> 96 hr*mg/L sparse_auc_se hr*mg/L
#> 97 hr*mg/L aucivlast hr*mg/L
#> 98 hr*mg/L aucivall hr*mg/L
#> 99 hr*mg/L aucivint.last hr*mg/L
#> 100 hr*mg/L aucivint.all hr*mg/L
#> 101 hr*mg/L aucinf.obs hr*mg/L
#> 102 hr*mg/L aucinf.pred hr*mg/L
#> 103 hr*mg/L aucint.inf.obs hr*mg/L
#> 104 hr*mg/L aucint.inf.obs.dose hr*mg/L
#> 105 hr*mg/L aucint.inf.pred hr*mg/L
#> 106 hr*mg/L aucint.inf.pred.dose hr*mg/L
#> 107 hr*mg/L aucivinf.obs hr*mg/L
#> 108 hr*mg/L aucivinf.pred hr*mg/L
#> 109 hr^2*mg/L aumclast hr^2*mg/L
#> 110 hr^2*mg/L aumcall hr^2*mg/L
#> 111 hr^2*mg/L aumcinf.obs hr^2*mg/L
#> 112 hr^2*mg/L aumcinf.pred hr^2*mg/L
#> 113 hr*mg ermax hr*mg
#> 114 (hr*mg/L)/(mg/kg) auclast.dn (hr*mg/L)/(mg/kg)
#> 115 (hr*mg/L)/(mg/kg) aucall.dn (hr*mg/L)/(mg/kg)
#> 116 (hr*mg/L)/(mg/kg) aucinf.obs.dn (hr*mg/L)/(mg/kg)
#> 117 (hr*mg/L)/(mg/kg) aucinf.pred.dn (hr*mg/L)/(mg/kg)
#> 118 (hr^2*mg/L)/(mg/kg) aumclast.dn (hr^2*mg/L)/(mg/kg)
#> 119 (hr^2*mg/L)/(mg/kg) aumcall.dn (hr^2*mg/L)/(mg/kg)
#> 120 (hr^2*mg/L)/(mg/kg) aumcinf.obs.dn (hr^2*mg/L)/(mg/kg)
#> 121 (hr^2*mg/L)/(mg/kg) aumcinf.pred.dn (hr^2*mg/L)/(mg/kg)
#> 122 (mg/kg)/(hr*mg/L) cl.last (mg/kg)/(hr*mg/L)
#> 123 (mg/kg)/(hr*mg/L) cl.all (mg/kg)/(hr*mg/L)
#> 124 (mg/kg)/(hr*mg/L) cl.obs (mg/kg)/(hr*mg/L)
#> 125 (mg/kg)/(hr*mg/L) cl.pred (mg/kg)/(hr*mg/L)
#> 126 mg/(hr*mg/L) clr.last mg/(hr*mg/L)
#> 127 mg/(hr*mg/L) clr.obs mg/(hr*mg/L)
#> 128 mg/(hr*mg/L) clr.pred mg/(hr*mg/L)
#> 129 (mg/(hr*mg/L))/(mg/kg) clr.last.dn (mg/(hr*mg/L))/(mg/kg)
#> 130 (mg/(hr*mg/L))/(mg/kg) clr.obs.dn (mg/(hr*mg/L))/(mg/kg)
#> 131 (mg/(hr*mg/L))/(mg/kg) clr.pred.dn (mg/(hr*mg/L))/(mg/kg)
#> conversion_factor
#> 1 1.000000000
#> 2 1.000000000
#> 3 1.000000000
#> 4 1.000000000
#> 5 1.000000000
#> 6 1.000000000
#> 7 1.000000000
#> 8 1.000000000
#> 9 1.000000000
#> 10 1.000000000
#> 11 1.000000000
#> 12 1.000000000
#> 13 1.000000000
#> 14 1.000000000
#> 15 1.000000000
#> 16 1.000000000
#> 17 1.000000000
#> 18 1.000000000
#> 19 1.000000000
#> 20 1.000000000
#> 21 1.000000000
#> 22 1.000000000
#> 23 1.000000000
#> 24 1.000000000
#> 25 1.000000000
#> 26 1.000000000
#> 27 1.000000000
#> 28 1.000000000
#> 29 1.000000000
#> 30 1.000000000
#> 31 1.000000000
#> 32 1.000000000
#> 33 1.000000000
#> 34 1.000000000
#> 35 1.000000000
#> 36 1.000000000
#> 37 1.000000000
#> 38 1.000000000
#> 39 1.000000000
#> 40 1.000000000
#> 41 1.000000000
#> 42 1.000000000
#> 43 1.000000000
#> 44 1.000000000
#> 45 1.000000000
#> 46 1.000000000
#> 47 1.000000000
#> 48 1.000000000
#> 49 1.000000000
#> 50 1.000000000
#> 51 1.000000000
#> 52 1.000000000
#> 53 1.000000000
#> 54 0.007240029
#> 55 0.007240029
#> 56 0.007240029
#> 57 0.007240029
#> 58 0.007240029
#> 59 0.007240029
#> 60 0.007240029
#> 61 0.007240029
#> 62 0.007240029
#> 63 0.007240029
#> 64 0.007240029
#> 65 0.007240029
#> 66 0.007240029
#> 67 1.000000000
#> 68 1.000000000
#> 69 1.000000000
#> 70 1.000000000
#> 71 1.000000000
#> 72 1.000000000
#> 73 1.000000000
#> 74 1.000000000
#> 75 1.000000000
#> 76 1.000000000
#> 77 1.000000000
#> 78 1.000000000
#> 79 1.000000000
#> 80 1.000000000
#> 81 1.000000000
#> 82 1.000000000
#> 83 1.000000000
#> 84 1.000000000
#> 85 1.000000000
#> 86 1.000000000
#> 87 1.000000000
#> 88 1.000000000
#> 89 1.000000000
#> 90 1.000000000
#> 91 1.000000000
#> 92 1.000000000
#> 93 1.000000000
#> 94 1.000000000
#> 95 1.000000000
#> 96 1.000000000
#> 97 1.000000000
#> 98 1.000000000
#> 99 1.000000000
#> 100 1.000000000
#> 101 1.000000000
#> 102 1.000000000
#> 103 1.000000000
#> 104 1.000000000
#> 105 1.000000000
#> 106 1.000000000
#> 107 1.000000000
#> 108 1.000000000
#> 109 1.000000000
#> 110 1.000000000
#> 111 1.000000000
#> 112 1.000000000
#> 113 1.000000000
#> 114 1.000000000
#> 115 1.000000000
#> 116 1.000000000
#> 117 1.000000000
#> 118 1.000000000
#> 119 1.000000000
#> 120 1.000000000
#> 121 1.000000000
#> 122 1.000000000
#> 123 1.000000000
#> 124 1.000000000
#> 125 1.000000000
#> 126 1.000000000
#> 127 1.000000000
#> 128 1.000000000
#> 129 1.000000000
#> 130 1.000000000
#> 131 1.000000000
# This will make all time-related parameters use "day" even though the
# original units are "hr"
pknca_units_table(
concu = "ng/mL", doseu = "mg/kg", timeu = "hr", amountu = "mg",
timeu_pref = "day"
)
#> PPORRESU PPTESTCD PPSTRESU
#> 1 unitless r.squared unitless
#> 2 unitless adj.r.squared unitless
#> 3 unitless lambda.z.corrxy unitless
#> 4 fraction f fraction
#> 5 fraction ptr fraction
#> 6 fraction span.ratio fraction
#> 7 % deg.fluc %
#> 8 % swing %
#> 9 % aucivpbextlast %
#> 10 % aucivpbextall %
#> 11 % aucivpbextint.last %
#> 12 % aucivpbextint.all %
#> 13 % aucivpbextinf.obs %
#> 14 % aucivpbextinf.pred %
#> 15 % aucpext.obs %
#> 16 % aucpext.pred %
#> 17 count count_conc count
#> 18 count count_conc_measured count
#> 19 count sparse_auc_df count
#> 20 count lambda.z.n.points count
#> 21 hr start day
#> 22 hr end day
#> 23 hr tmax day
#> 24 hr tlast day
#> 25 hr tfirst day
#> 26 hr mrt.last day
#> 27 hr mrt.iv.last day
#> 28 hr tlag day
#> 29 hr ertlst day
#> 30 hr ertmax day
#> 31 hr time_above day
#> 32 hr half.life day
#> 33 hr lambda.z.time.first day
#> 34 hr lambda.z.time.last day
#> 35 hr thalf.eff.last day
#> 36 hr thalf.eff.iv.last day
#> 37 hr mrt.obs day
#> 38 hr mrt.pred day
#> 39 hr mrt.iv.obs day
#> 40 hr mrt.iv.pred day
#> 41 hr mrt.md.obs day
#> 42 hr mrt.md.pred day
#> 43 hr thalf.eff.obs day
#> 44 hr thalf.eff.pred day
#> 45 hr thalf.eff.iv.obs day
#> 46 hr thalf.eff.iv.pred day
#> 47 1/hr lambda.z 1/day
#> 48 1/hr kel.last 1/day
#> 49 1/hr kel.iv.last 1/day
#> 50 1/hr kel.obs 1/day
#> 51 1/hr kel.pred 1/day
#> 52 1/hr kel.iv.obs 1/day
#> 53 1/hr kel.iv.pred 1/day
#> 54 ng/mL c0 ng/mL
#> 55 ng/mL cmax ng/mL
#> 56 ng/mL cmin ng/mL
#> 57 ng/mL clast.obs ng/mL
#> 58 ng/mL cav ng/mL
#> 59 ng/mL cav.int.last ng/mL
#> 60 ng/mL cav.int.all ng/mL
#> 61 ng/mL ctrough ng/mL
#> 62 ng/mL cstart ng/mL
#> 63 ng/mL ceoi ng/mL
#> 64 ng/mL clast.pred ng/mL
#> 65 ng/mL cav.int.inf.obs ng/mL
#> 66 ng/mL cav.int.inf.pred ng/mL
#> 67 mg ae mg
#> 68 mg/(mg/kg) fe mg/(mg/kg)
#> 69 mg/kg totdose mg/kg
#> 70 (ng/mL)/(mg/kg) cmax.dn (ng/mL)/(mg/kg)
#> 71 (ng/mL)/(mg/kg) cmin.dn (ng/mL)/(mg/kg)
#> 72 (ng/mL)/(mg/kg) clast.obs.dn (ng/mL)/(mg/kg)
#> 73 (ng/mL)/(mg/kg) clast.pred.dn (ng/mL)/(mg/kg)
#> 74 (ng/mL)/(mg/kg) cav.dn (ng/mL)/(mg/kg)
#> 75 (ng/mL)/(mg/kg) ctrough.dn (ng/mL)/(mg/kg)
#> 76 (mg/kg)/(ng/mL) vss.last (mg/kg)/(ng/mL)
#> 77 (mg/kg)/(ng/mL) vss.iv.last (mg/kg)/(ng/mL)
#> 78 (mg/kg)/(ng/mL) volpk (mg/kg)/(ng/mL)
#> 79 (mg/kg)/(ng/mL) vz.obs (mg/kg)/(ng/mL)
#> 80 (mg/kg)/(ng/mL) vz.pred (mg/kg)/(ng/mL)
#> 81 (mg/kg)/(ng/mL) vss.obs (mg/kg)/(ng/mL)
#> 82 (mg/kg)/(ng/mL) vss.pred (mg/kg)/(ng/mL)
#> 83 (mg/kg)/(ng/mL) vss.iv.obs (mg/kg)/(ng/mL)
#> 84 (mg/kg)/(ng/mL) vss.iv.pred (mg/kg)/(ng/mL)
#> 85 (mg/kg)/(ng/mL) vss.md.obs (mg/kg)/(ng/mL)
#> 86 (mg/kg)/(ng/mL) vss.md.pred (mg/kg)/(ng/mL)
#> 87 hr*ng/mL auclast day*ng/mL
#> 88 hr*ng/mL aucall day*ng/mL
#> 89 hr*ng/mL aucint.last day*ng/mL
#> 90 hr*ng/mL aucint.last.dose day*ng/mL
#> 91 hr*ng/mL aucint.all day*ng/mL
#> 92 hr*ng/mL aucint.all.dose day*ng/mL
#> 93 hr*ng/mL aucabove.predose.all day*ng/mL
#> 94 hr*ng/mL aucabove.trough.all day*ng/mL
#> 95 hr*ng/mL sparse_auclast day*ng/mL
#> 96 hr*ng/mL sparse_auc_se day*ng/mL
#> 97 hr*ng/mL aucivlast day*ng/mL
#> 98 hr*ng/mL aucivall day*ng/mL
#> 99 hr*ng/mL aucivint.last day*ng/mL
#> 100 hr*ng/mL aucivint.all day*ng/mL
#> 101 hr*ng/mL aucinf.obs day*ng/mL
#> 102 hr*ng/mL aucinf.pred day*ng/mL
#> 103 hr*ng/mL aucint.inf.obs day*ng/mL
#> 104 hr*ng/mL aucint.inf.obs.dose day*ng/mL
#> 105 hr*ng/mL aucint.inf.pred day*ng/mL
#> 106 hr*ng/mL aucint.inf.pred.dose day*ng/mL
#> 107 hr*ng/mL aucivinf.obs day*ng/mL
#> 108 hr*ng/mL aucivinf.pred day*ng/mL
#> 109 hr^2*ng/mL aumclast day^2*ng/mL
#> 110 hr^2*ng/mL aumcall day^2*ng/mL
#> 111 hr^2*ng/mL aumcinf.obs day^2*ng/mL
#> 112 hr^2*ng/mL aumcinf.pred day^2*ng/mL
#> 113 hr*mg ermax day*mg
#> 114 (hr*ng/mL)/(mg/kg) auclast.dn (day*ng/mL)/(mg/kg)
#> 115 (hr*ng/mL)/(mg/kg) aucall.dn (day*ng/mL)/(mg/kg)
#> 116 (hr*ng/mL)/(mg/kg) aucinf.obs.dn (day*ng/mL)/(mg/kg)
#> 117 (hr*ng/mL)/(mg/kg) aucinf.pred.dn (day*ng/mL)/(mg/kg)
#> 118 (hr^2*ng/mL)/(mg/kg) aumclast.dn (day^2*ng/mL)/(mg/kg)
#> 119 (hr^2*ng/mL)/(mg/kg) aumcall.dn (day^2*ng/mL)/(mg/kg)
#> 120 (hr^2*ng/mL)/(mg/kg) aumcinf.obs.dn (day^2*ng/mL)/(mg/kg)
#> 121 (hr^2*ng/mL)/(mg/kg) aumcinf.pred.dn (day^2*ng/mL)/(mg/kg)
#> 122 (mg/kg)/(hr*ng/mL) cl.last (mg/kg)/(day*ng/mL)
#> 123 (mg/kg)/(hr*ng/mL) cl.all (mg/kg)/(day*ng/mL)
#> 124 (mg/kg)/(hr*ng/mL) cl.obs (mg/kg)/(day*ng/mL)
#> 125 (mg/kg)/(hr*ng/mL) cl.pred (mg/kg)/(day*ng/mL)
#> 126 mg/(hr*ng/mL) clr.last mg/(day*ng/mL)
#> 127 mg/(hr*ng/mL) clr.obs mg/(day*ng/mL)
#> 128 mg/(hr*ng/mL) clr.pred mg/(day*ng/mL)
#> 129 (mg/(hr*ng/mL))/(mg/kg) clr.last.dn (mg/(day*ng/mL))/(mg/kg)
#> 130 (mg/(hr*ng/mL))/(mg/kg) clr.obs.dn (mg/(day*ng/mL))/(mg/kg)
#> 131 (mg/(hr*ng/mL))/(mg/kg) clr.pred.dn (mg/(day*ng/mL))/(mg/kg)
#> conversion_factor
#> 1 1.000000000
#> 2 1.000000000
#> 3 1.000000000
#> 4 1.000000000
#> 5 1.000000000
#> 6 1.000000000
#> 7 1.000000000
#> 8 1.000000000
#> 9 1.000000000
#> 10 1.000000000
#> 11 1.000000000
#> 12 1.000000000
#> 13 1.000000000
#> 14 1.000000000
#> 15 1.000000000
#> 16 1.000000000
#> 17 1.000000000
#> 18 1.000000000
#> 19 1.000000000
#> 20 1.000000000
#> 21 0.041666667
#> 22 0.041666667
#> 23 0.041666667
#> 24 0.041666667
#> 25 0.041666667
#> 26 0.041666667
#> 27 0.041666667
#> 28 0.041666667
#> 29 0.041666667
#> 30 0.041666667
#> 31 0.041666667
#> 32 0.041666667
#> 33 0.041666667
#> 34 0.041666667
#> 35 0.041666667
#> 36 0.041666667
#> 37 0.041666667
#> 38 0.041666667
#> 39 0.041666667
#> 40 0.041666667
#> 41 0.041666667
#> 42 0.041666667
#> 43 0.041666667
#> 44 0.041666667
#> 45 0.041666667
#> 46 0.041666667
#> 47 24.000000000
#> 48 24.000000000
#> 49 24.000000000
#> 50 24.000000000
#> 51 24.000000000
#> 52 24.000000000
#> 53 24.000000000
#> 54 1.000000000
#> 55 1.000000000
#> 56 1.000000000
#> 57 1.000000000
#> 58 1.000000000
#> 59 1.000000000
#> 60 1.000000000
#> 61 1.000000000
#> 62 1.000000000
#> 63 1.000000000
#> 64 1.000000000
#> 65 1.000000000
#> 66 1.000000000
#> 67 1.000000000
#> 68 1.000000000
#> 69 1.000000000
#> 70 1.000000000
#> 71 1.000000000
#> 72 1.000000000
#> 73 1.000000000
#> 74 1.000000000
#> 75 1.000000000
#> 76 1.000000000
#> 77 1.000000000
#> 78 1.000000000
#> 79 1.000000000
#> 80 1.000000000
#> 81 1.000000000
#> 82 1.000000000
#> 83 1.000000000
#> 84 1.000000000
#> 85 1.000000000
#> 86 1.000000000
#> 87 0.041666667
#> 88 0.041666667
#> 89 0.041666667
#> 90 0.041666667
#> 91 0.041666667
#> 92 0.041666667
#> 93 0.041666667
#> 94 0.041666667
#> 95 0.041666667
#> 96 0.041666667
#> 97 0.041666667
#> 98 0.041666667
#> 99 0.041666667
#> 100 0.041666667
#> 101 0.041666667
#> 102 0.041666667
#> 103 0.041666667
#> 104 0.041666667
#> 105 0.041666667
#> 106 0.041666667
#> 107 0.041666667
#> 108 0.041666667
#> 109 0.001736111
#> 110 0.001736111
#> 111 0.001736111
#> 112 0.001736111
#> 113 0.041666667
#> 114 0.041666667
#> 115 0.041666667
#> 116 0.041666667
#> 117 0.041666667
#> 118 0.001736111
#> 119 0.001736111
#> 120 0.001736111
#> 121 0.001736111
#> 122 24.000000000
#> 123 24.000000000
#> 124 24.000000000
#> 125 24.000000000
#> 126 24.000000000
#> 127 24.000000000
#> 128 24.000000000
#> 129 24.000000000
#> 130 24.000000000
#> 131 24.000000000