Calculate the terminal volume of distribution (Vz)

Calculate the terminal volume of distribution (Vz)

Usage

pk.calc.vz(cl, lambda.z)

pk.calc.vss(cl, mrt)

Arguments

cl

the clearance (or apparent observed clearance)

lambda.z

The elimination rate (in units of inverse time) for extrapolation

mrt

the mean residence time

Value

the volume of distribution at steady-state

Details

vz is cl/lambda.z.

vss is cl*mrt.

Functions

• pk.calc.vss(): Steady-state volume of distribution (Vss)

See also

Other Clearance and volume parameters: pk.calc.cl(), pk.calc.kel()