Get the columns that can be used in an interval specification
Source:R/001-add.interval.col.R
get.interval.cols.RdGet the columns that can be used in an interval specification
Value
A list with named elements for each parameter. Each list element contains the parameter definition.
See also
check.interval.specification() and the vignette "Selection of
Calculation Intervals"
Other Interval specifications:
add.interval.col(),
check.interval.specification(),
choose.auc.intervals(),
get.parameter.deps()
Examples
get.interval.cols()
#> $start
#> $start$FUN
#> [1] NA
#>
#> $start$values
#> function (x, ...) .Primitive("as.double")
#>
#> $start$unit_type
#> [1] "time"
#>
#> $start$pretty_name
#> [1] "Interval Start"
#>
#> $start$desc
#> [1] "Starting time of the interval"
#>
#> $start$sparse
#> [1] FALSE
#>
#> $start$formalsmap
#> list()
#>
#> $start$depends
#> NULL
#>
#> $start$datatype
#> [1] "interval"
#>
#> $start$pptestcd_cdisc
#> [1] "start"
#>
#> $start$pptest_cdisc
#> [1] "Starting time of the interval"
#>
#>
#> $end
#> $end$FUN
#> [1] NA
#>
#> $end$values
#> function (x, ...) .Primitive("as.double")
#>
#> $end$unit_type
#> [1] "time"
#>
#> $end$pretty_name
#> [1] "Interval End"
#>
#> $end$desc
#> [1] "Ending time of the interval (potentially infinity)"
#>
#> $end$sparse
#> [1] FALSE
#>
#> $end$formalsmap
#> list()
#>
#> $end$depends
#> NULL
#>
#> $end$datatype
#> [1] "interval"
#>
#> $end$pptestcd_cdisc
#> [1] "end"
#>
#> $end$pptest_cdisc
#> [1] "Ending time of the interval (potentially infinity)"
#>
#>
#> $auclast
#> $auclast$FUN
#> [1] "pk.calc.auc.last"
#>
#> $auclast$values
#> [1] FALSE TRUE
#>
#> $auclast$unit_type
#> [1] "auc"
#>
#> $auclast$pretty_name
#> [1] "AUClast"
#>
#> $auclast$desc
#> [1] "The area under the concentration time curve from the beginning of the interval to the last concentration above the limit of quantification"
#>
#> $auclast$sparse
#> [1] FALSE
#>
#> $auclast$formalsmap
#> list()
#>
#> $auclast$depends
#> NULL
#>
#> $auclast$datatype
#> [1] "interval"
#>
#> $auclast$pptestcd_cdisc
#> [1] "AUCLST"
#>
#> $auclast$pptest_cdisc
#> [1] "AUC to Last Nonzero Conc"
#>
#>
#> $aucall
#> $aucall$FUN
#> [1] "pk.calc.auc.all"
#>
#> $aucall$values
#> [1] FALSE TRUE
#>
#> $aucall$unit_type
#> [1] "auc"
#>
#> $aucall$pretty_name
#> [1] "AUCall"
#>
#> $aucall$desc
#> [1] "The area under the concentration time curve from the beginning of the interval to the last concentration above the limit of quantification plus the triangle from that last concentration to 0 at the first concentration below the limit of quantification"
#>
#> $aucall$sparse
#> [1] FALSE
#>
#> $aucall$formalsmap
#> list()
#>
#> $aucall$depends
#> NULL
#>
#> $aucall$datatype
#> [1] "interval"
#>
#> $aucall$pptestcd_cdisc
#> [1] "AUCALL"
#>
#> $aucall$pptest_cdisc
#> [1] "AUC All"
#>
#>
#> $aumclast
#> $aumclast$FUN
#> [1] "pk.calc.aumc.last"
#>
#> $aumclast$values
#> [1] FALSE TRUE
#>
#> $aumclast$unit_type
#> [1] "aumc"
#>
#> $aumclast$pretty_name
#> [1] "AUMC,last"
#>
#> $aumclast$desc
#> [1] "The area under the concentration time moment curve from the beginning of the interval to the last concentration above the limit of quantification"
#>
#> $aumclast$sparse
#> [1] FALSE
#>
#> $aumclast$formalsmap
#> list()
#>
#> $aumclast$depends
#> NULL
#>
#> $aumclast$datatype
#> [1] "interval"
#>
#> $aumclast$pptestcd_cdisc
#> [1] "AUMCLST"
#>
#> $aumclast$pptest_cdisc
#> [1] "AUMC to Last Nonzero Conc"
#>
#>
#> $aumcall
#> $aumcall$FUN
#> [1] "pk.calc.aumc.all"
#>
#> $aumcall$values
#> [1] FALSE TRUE
#>
#> $aumcall$unit_type
#> [1] "aumc"
#>
#> $aumcall$pretty_name
#> [1] "AUMC,all"
#>
#> $aumcall$desc
#> [1] "The area under the concentration time moment curve from the beginning of the interval to the last concentration above the limit of quantification plus the moment of the triangle from that last concentration to 0 at the first concentration below the limit of quantification"
#>
#> $aumcall$sparse
#> [1] FALSE
#>
#> $aumcall$formalsmap
#> list()
#>
#> $aumcall$depends
#> NULL
#>
#> $aumcall$datatype
#> [1] "interval"
#>
#> $aumcall$pptestcd_cdisc
#> [1] "AUMCALL"
#>
#> $aumcall$pptest_cdisc
#> [1] "AUMC All"
#>
#>
#> $aucint.last
#> $aucint.last$FUN
#> [1] "pk.calc.aucint.last"
#>
#> $aucint.last$values
#> [1] FALSE TRUE
#>
#> $aucint.last$unit_type
#> [1] "auc"
#>
#> $aucint.last$pretty_name
#> [1] "AUCint (based on AUClast extrapolation)"
#>
#> $aucint.last$desc
#> [1] "The area under the concentration time curve in the interval extrapolating from Tlast to infinity with zeros (matching AUClast)"
#>
#> $aucint.last$sparse
#> [1] FALSE
#>
#> $aucint.last$formalsmap
#> $aucint.last$formalsmap$conc
#> [1] "conc.group"
#>
#> $aucint.last$formalsmap$time
#> [1] "time.group"
#>
#> $aucint.last$formalsmap$time.dose
#> NULL
#>
#>
#> $aucint.last$depends
#> NULL
#>
#> $aucint.last$datatype
#> [1] "interval"
#>
#> $aucint.last$pptestcd_cdisc
#> [1] "AUCINT"
#>
#> $aucint.last$pptest_cdisc
#> [1] "AUC from T1 to T2"
#>
#>
#> $aucint.last.dose
#> $aucint.last.dose$FUN
#> [1] "pk.calc.aucint.last"
#>
#> $aucint.last.dose$values
#> [1] FALSE TRUE
#>
#> $aucint.last.dose$unit_type
#> [1] "auc"
#>
#> $aucint.last.dose$pretty_name
#> [1] "AUCint (based on AUClast extrapolation, dose-aware)"
#>
#> $aucint.last.dose$desc
#> [1] "The area under the concentration time curve in the interval extrapolating from Tlast to infinity with zeros (matching AUClast) with dose-aware interpolation/extrapolation of concentrations"
#>
#> $aucint.last.dose$sparse
#> [1] FALSE
#>
#> $aucint.last.dose$formalsmap
#> $aucint.last.dose$formalsmap$conc
#> [1] "conc.group"
#>
#> $aucint.last.dose$formalsmap$time
#> [1] "time.group"
#>
#> $aucint.last.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#>
#>
#> $aucint.last.dose$depends
#> NULL
#>
#> $aucint.last.dose$datatype
#> [1] "interval"
#>
#> $aucint.last.dose$pptestcd_cdisc
#> [1] "AUCINTD"
#>
#> $aucint.last.dose$pptest_cdisc
#> [1] "AUC from T1 to T2 Normalized by Dose"
#>
#>
#> $aucint.all
#> $aucint.all$FUN
#> [1] "pk.calc.aucint.all"
#>
#> $aucint.all$values
#> [1] FALSE TRUE
#>
#> $aucint.all$unit_type
#> [1] "auc"
#>
#> $aucint.all$pretty_name
#> [1] "AUCint (based on AUCall extrapolation)"
#>
#> $aucint.all$desc
#> [1] "The area under the concentration time curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUCall)"
#>
#> $aucint.all$sparse
#> [1] FALSE
#>
#> $aucint.all$formalsmap
#> $aucint.all$formalsmap$conc
#> [1] "conc.group"
#>
#> $aucint.all$formalsmap$time
#> [1] "time.group"
#>
#> $aucint.all$formalsmap$time.dose
#> NULL
#>
#>
#> $aucint.all$depends
#> NULL
#>
#> $aucint.all$datatype
#> [1] "interval"
#>
#> $aucint.all$pptestcd_cdisc
#> [1] "AUCINTA"
#>
#> $aucint.all$pptest_cdisc
#> [1] "AUCint (based on AUCall extrapolation)"
#>
#>
#> $aucint.all.dose
#> $aucint.all.dose$FUN
#> [1] "pk.calc.aucint.all"
#>
#> $aucint.all.dose$values
#> [1] FALSE TRUE
#>
#> $aucint.all.dose$unit_type
#> [1] "auc"
#>
#> $aucint.all.dose$pretty_name
#> [1] "AUCint (based on AUCall extrapolation, dose-aware)"
#>
#> $aucint.all.dose$desc
#> [1] "The area under the concentration time curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUCall) with dose-aware interpolation/extrapolation of concentrations"
#>
#> $aucint.all.dose$sparse
#> [1] FALSE
#>
#> $aucint.all.dose$formalsmap
#> $aucint.all.dose$formalsmap$conc
#> [1] "conc.group"
#>
#> $aucint.all.dose$formalsmap$time
#> [1] "time.group"
#>
#> $aucint.all.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#>
#>
#> $aucint.all.dose$depends
#> NULL
#>
#> $aucint.all.dose$datatype
#> [1] "interval"
#>
#> $aucint.all.dose$pptestcd_cdisc
#> [1] "AUCINTAD"
#>
#> $aucint.all.dose$pptest_cdisc
#> [1] "AUCint (based on AUCall extrapolation, dose-aware)"
#>
#>
#> $aumcint.last
#> $aumcint.last$FUN
#> [1] "pk.calc.aumcint.last"
#>
#> $aumcint.last$values
#> [1] FALSE TRUE
#>
#> $aumcint.last$unit_type
#> [1] "aumc"
#>
#> $aumcint.last$pretty_name
#> [1] "AUMCint (based on AUMClast extrapolation)"
#>
#> $aumcint.last$desc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with zeros (matching AUMClast)"
#>
#> $aumcint.last$sparse
#> [1] FALSE
#>
#> $aumcint.last$formalsmap
#> $aumcint.last$formalsmap$conc
#> [1] "conc.group"
#>
#> $aumcint.last$formalsmap$time
#> [1] "time.group"
#>
#> $aumcint.last$formalsmap$time.dose
#> NULL
#>
#>
#> $aumcint.last$depends
#> NULL
#>
#> $aumcint.last$datatype
#> [1] "interval"
#>
#> $aumcint.last$pptestcd_cdisc
#> [1] "aumcint.last"
#>
#> $aumcint.last$pptest_cdisc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with zeros (matching AUMClast)"
#>
#>
#> $aumcint.last.dose
#> $aumcint.last.dose$FUN
#> [1] "pk.calc.aumcint.last"
#>
#> $aumcint.last.dose$values
#> [1] FALSE TRUE
#>
#> $aumcint.last.dose$unit_type
#> [1] "aumc"
#>
#> $aumcint.last.dose$pretty_name
#> [1] "AUMCint (based on AUMClast extrapolation, dose-aware)"
#>
#> $aumcint.last.dose$desc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with zeros (matching AUMClast) with dose-aware interpolation/extrapolation of concentrations"
#>
#> $aumcint.last.dose$sparse
#> [1] FALSE
#>
#> $aumcint.last.dose$formalsmap
#> $aumcint.last.dose$formalsmap$conc
#> [1] "conc.group"
#>
#> $aumcint.last.dose$formalsmap$time
#> [1] "time.group"
#>
#> $aumcint.last.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#>
#>
#> $aumcint.last.dose$depends
#> NULL
#>
#> $aumcint.last.dose$datatype
#> [1] "interval"
#>
#> $aumcint.last.dose$pptestcd_cdisc
#> [1] "aumcint.last.dose"
#>
#> $aumcint.last.dose$pptest_cdisc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with zeros (matching AUMClast) with dose-aware interpolation/extrapolation of concentrations"
#>
#>
#> $aumcint.all
#> $aumcint.all$FUN
#> [1] "pk.calc.aumcint.all"
#>
#> $aumcint.all$values
#> [1] FALSE TRUE
#>
#> $aumcint.all$unit_type
#> [1] "aumc"
#>
#> $aumcint.all$pretty_name
#> [1] "AUMCint (based on AUMCall extrapolation)"
#>
#> $aumcint.all$desc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUMCall)"
#>
#> $aumcint.all$sparse
#> [1] FALSE
#>
#> $aumcint.all$formalsmap
#> $aumcint.all$formalsmap$conc
#> [1] "conc.group"
#>
#> $aumcint.all$formalsmap$time
#> [1] "time.group"
#>
#> $aumcint.all$formalsmap$time.dose
#> NULL
#>
#>
#> $aumcint.all$depends
#> NULL
#>
#> $aumcint.all$datatype
#> [1] "interval"
#>
#> $aumcint.all$pptestcd_cdisc
#> [1] "aumcint.all"
#>
#> $aumcint.all$pptest_cdisc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUMCall)"
#>
#>
#> $aumcint.all.dose
#> $aumcint.all.dose$FUN
#> [1] "pk.calc.aumcint.all"
#>
#> $aumcint.all.dose$values
#> [1] FALSE TRUE
#>
#> $aumcint.all.dose$unit_type
#> [1] "aumc"
#>
#> $aumcint.all.dose$pretty_name
#> [1] "AUMCint (based on AUMCall extrapolation, dose-aware)"
#>
#> $aumcint.all.dose$desc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUMCall) with dose-aware interpolation/extrapolation of concentrations"
#>
#> $aumcint.all.dose$sparse
#> [1] FALSE
#>
#> $aumcint.all.dose$formalsmap
#> $aumcint.all.dose$formalsmap$conc
#> [1] "conc.group"
#>
#> $aumcint.all.dose$formalsmap$time
#> [1] "time.group"
#>
#> $aumcint.all.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#>
#>
#> $aumcint.all.dose$depends
#> NULL
#>
#> $aumcint.all.dose$datatype
#> [1] "interval"
#>
#> $aumcint.all.dose$pptestcd_cdisc
#> [1] "aumcint.all.dose"
#>
#> $aumcint.all.dose$pptest_cdisc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUMCall) with dose-aware interpolation/extrapolation of concentrations"
#>
#>
#> $c0
#> $c0$FUN
#> [1] "pk.calc.c0"
#>
#> $c0$values
#> [1] FALSE TRUE
#>
#> $c0$unit_type
#> [1] "conc"
#>
#> $c0$pretty_name
#> [1] "C0"
#>
#> $c0$desc
#> [1] "Initial concentration after an IV bolus"
#>
#> $c0$sparse
#> [1] FALSE
#>
#> $c0$formalsmap
#> list()
#>
#> $c0$depends
#> NULL
#>
#> $c0$datatype
#> [1] "interval"
#>
#> $c0$pptestcd_cdisc
#> [1] "C0"
#>
#> $c0$pptest_cdisc
#> [1] "Initial Conc"
#>
#>
#> $cmax
#> $cmax$FUN
#> [1] "pk.calc.cmax"
#>
#> $cmax$values
#> [1] FALSE TRUE
#>
#> $cmax$unit_type
#> [1] "conc"
#>
#> $cmax$pretty_name
#> [1] "Cmax"
#>
#> $cmax$desc
#> [1] "Maximum observed concentration"
#>
#> $cmax$sparse
#> [1] FALSE
#>
#> $cmax$formalsmap
#> list()
#>
#> $cmax$depends
#> NULL
#>
#> $cmax$datatype
#> [1] "interval"
#>
#> $cmax$pptestcd_cdisc
#> [1] "CMAX"
#>
#> $cmax$pptest_cdisc
#> [1] "Max Conc"
#>
#>
#> $cmin
#> $cmin$FUN
#> [1] "pk.calc.cmin"
#>
#> $cmin$values
#> [1] FALSE TRUE
#>
#> $cmin$unit_type
#> [1] "conc"
#>
#> $cmin$pretty_name
#> [1] "Cmin"
#>
#> $cmin$desc
#> [1] "Minimum observed concentration"
#>
#> $cmin$sparse
#> [1] FALSE
#>
#> $cmin$formalsmap
#> list()
#>
#> $cmin$depends
#> NULL
#>
#> $cmin$datatype
#> [1] "interval"
#>
#> $cmin$pptestcd_cdisc
#> [1] "CMIN"
#>
#> $cmin$pptest_cdisc
#> [1] "Min Conc"
#>
#>
#> $tmax
#> $tmax$FUN
#> [1] "pk.calc.tmax"
#>
#> $tmax$values
#> [1] FALSE TRUE
#>
#> $tmax$unit_type
#> [1] "time"
#>
#> $tmax$pretty_name
#> [1] "Tmax"
#>
#> $tmax$desc
#> [1] "Time of the maximum observed concentration"
#>
#> $tmax$sparse
#> [1] FALSE
#>
#> $tmax$formalsmap
#> list()
#>
#> $tmax$depends
#> NULL
#>
#> $tmax$datatype
#> [1] "interval"
#>
#> $tmax$pptestcd_cdisc
#> [1] "TMAX"
#>
#> $tmax$pptest_cdisc
#> [1] "Time of CMAX"
#>
#>
#> $tmin
#> $tmin$FUN
#> [1] "pk.calc.tmin"
#>
#> $tmin$values
#> [1] FALSE TRUE
#>
#> $tmin$unit_type
#> [1] "time"
#>
#> $tmin$pretty_name
#> [1] "Tmin"
#>
#> $tmin$desc
#> [1] "Time of the minimum observed concentration"
#>
#> $tmin$sparse
#> [1] FALSE
#>
#> $tmin$formalsmap
#> list()
#>
#> $tmin$depends
#> NULL
#>
#> $tmin$datatype
#> [1] "interval"
#>
#> $tmin$pptestcd_cdisc
#> [1] "TMIN"
#>
#> $tmin$pptest_cdisc
#> [1] "Time of CMIN Observation"
#>
#>
#> $tlast
#> $tlast$FUN
#> [1] "pk.calc.tlast"
#>
#> $tlast$values
#> [1] FALSE TRUE
#>
#> $tlast$unit_type
#> [1] "time"
#>
#> $tlast$pretty_name
#> [1] "Tlast"
#>
#> $tlast$desc
#> [1] "Time of the last concentration observed above the limit of quantification"
#>
#> $tlast$sparse
#> [1] FALSE
#>
#> $tlast$formalsmap
#> list()
#>
#> $tlast$depends
#> NULL
#>
#> $tlast$datatype
#> [1] "interval"
#>
#> $tlast$pptestcd_cdisc
#> [1] "TLST"
#>
#> $tlast$pptest_cdisc
#> [1] "Time of Last Nonzero Conc"
#>
#>
#> $tfirst
#> $tfirst$FUN
#> [1] "pk.calc.tfirst"
#>
#> $tfirst$values
#> [1] FALSE TRUE
#>
#> $tfirst$unit_type
#> [1] "time"
#>
#> $tfirst$pretty_name
#> [1] "Tfirst"
#>
#> $tfirst$desc
#> [1] "Time of the first concentration above the limit of quantification"
#>
#> $tfirst$sparse
#> [1] FALSE
#>
#> $tfirst$formalsmap
#> list()
#>
#> $tfirst$depends
#> NULL
#>
#> $tfirst$datatype
#> [1] "interval"
#>
#> $tfirst$pptestcd_cdisc
#> [1] "TFIRST"
#>
#> $tfirst$pptest_cdisc
#> [1] "Time of First Nonzero Conc"
#>
#>
#> $clast.obs
#> $clast.obs$FUN
#> [1] "pk.calc.clast.obs"
#>
#> $clast.obs$values
#> [1] FALSE TRUE
#>
#> $clast.obs$unit_type
#> [1] "conc"
#>
#> $clast.obs$pretty_name
#> [1] "Clast"
#>
#> $clast.obs$desc
#> [1] "The last concentration observed above the limit of quantification"
#>
#> $clast.obs$sparse
#> [1] FALSE
#>
#> $clast.obs$formalsmap
#> list()
#>
#> $clast.obs$depends
#> NULL
#>
#> $clast.obs$datatype
#> [1] "interval"
#>
#> $clast.obs$pptestcd_cdisc
#> [1] "CLST"
#>
#> $clast.obs$pptest_cdisc
#> [1] "Last Nonzero Conc"
#>
#>
#> $cl.last
#> $cl.last$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.last$values
#> [1] FALSE TRUE
#>
#> $cl.last$unit_type
#> [1] "clearance"
#>
#> $cl.last$pretty_name
#> [1] "CL (based on AUClast)"
#>
#> $cl.last$desc
#> [1] "Clearance or observed oral clearance calculated to Clast"
#>
#> $cl.last$sparse
#> [1] FALSE
#>
#> $cl.last$formalsmap
#> $cl.last$formalsmap$auc
#> [1] "auclast"
#>
#>
#> $cl.last$depends
#> [1] "auclast"
#>
#> $cl.last$datatype
#> [1] "interval"
#>
#> $cl.last$pptestcd_cdisc
#> $cl.last$pptestcd_cdisc$route
#> $cl.last$pptestcd_cdisc$route$extravascular
#> [1] "CLF/FLST"
#>
#> $cl.last$pptestcd_cdisc$route$intravascular
#> [1] "CLLST"
#>
#>
#>
#> $cl.last$pptest_cdisc
#> $cl.last$pptest_cdisc$route
#> $cl.last$pptest_cdisc$route$extravascular
#> [1] "CL by F (based on AUClast)"
#>
#> $cl.last$pptest_cdisc$route$intravascular
#> [1] "CL (based on AUClast)"
#>
#>
#>
#>
#> $cl.all
#> $cl.all$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.all$values
#> [1] FALSE TRUE
#>
#> $cl.all$unit_type
#> [1] "clearance"
#>
#> $cl.all$pretty_name
#> [1] "CL (based on AUCall)"
#>
#> $cl.all$desc
#> [1] "Clearance or observed oral clearance calculated with AUCall"
#>
#> $cl.all$sparse
#> [1] FALSE
#>
#> $cl.all$formalsmap
#> $cl.all$formalsmap$auc
#> [1] "aucall"
#>
#>
#> $cl.all$depends
#> [1] "aucall"
#>
#> $cl.all$datatype
#> [1] "interval"
#>
#> $cl.all$pptestcd_cdisc
#> $cl.all$pptestcd_cdisc$route
#> $cl.all$pptestcd_cdisc$route$extravascular
#> [1] "CLF/FALL"
#>
#> $cl.all$pptestcd_cdisc$route$intravascular
#> [1] "CLALL"
#>
#>
#>
#> $cl.all$pptest_cdisc
#> $cl.all$pptest_cdisc$route
#> $cl.all$pptest_cdisc$route$extravascular
#> [1] "CL by F (based on AUCall)"
#>
#> $cl.all$pptest_cdisc$route$intravascular
#> [1] "CL (based on AUCall)"
#>
#>
#>
#>
#> $cl.int.all
#> $cl.int.all$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.int.all$values
#> [1] FALSE TRUE
#>
#> $cl.int.all$unit_type
#> [1] "clearance"
#>
#> $cl.int.all$pretty_name
#> [1] "CL (based on AUCint.all)"
#>
#> $cl.int.all$desc
#> [1] "Clearance or observed oral clearance calculated with AUCint.all"
#>
#> $cl.int.all$sparse
#> [1] FALSE
#>
#> $cl.int.all$formalsmap
#> $cl.int.all$formalsmap$auc
#> [1] "aucint.all"
#>
#>
#> $cl.int.all$depends
#> [1] "aucint.all"
#>
#> $cl.int.all$datatype
#> [1] "interval"
#>
#> $cl.int.all$pptestcd_cdisc
#> [1] "cl.int.all"
#>
#> $cl.int.all$pptest_cdisc
#> [1] "Clearance or observed oral clearance calculated with AUCint.all"
#>
#>
#> $cl.int.last
#> $cl.int.last$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.int.last$values
#> [1] FALSE TRUE
#>
#> $cl.int.last$unit_type
#> [1] "clearance"
#>
#> $cl.int.last$pretty_name
#> [1] "CL (based on AUCint.last)"
#>
#> $cl.int.last$desc
#> [1] "Clearance or observed oral clearance calculated with AUCint.last"
#>
#> $cl.int.last$sparse
#> [1] FALSE
#>
#> $cl.int.last$formalsmap
#> $cl.int.last$formalsmap$auc
#> [1] "aucint.last"
#>
#>
#> $cl.int.last$depends
#> [1] "aucint.last"
#>
#> $cl.int.last$datatype
#> [1] "interval"
#>
#> $cl.int.last$pptestcd_cdisc
#> [1] "cl.int.last"
#>
#> $cl.int.last$pptest_cdisc
#> [1] "Clearance or observed oral clearance calculated with AUCint.last"
#>
#>
#> $f
#> $f$FUN
#> [1] "pk.calc.f"
#>
#> $f$values
#> [1] FALSE TRUE
#>
#> $f$unit_type
#> [1] "fraction"
#>
#> $f$pretty_name
#> [1] "Bioavailability"
#>
#> $f$desc
#> [1] "Bioavailability or relative bioavailability"
#>
#> $f$sparse
#> [1] FALSE
#>
#> $f$formalsmap
#> list()
#>
#> $f$depends
#> NULL
#>
#> $f$datatype
#> [1] "interval"
#>
#> $f$pptestcd_cdisc
#> [1] "FAB"
#>
#> $f$pptest_cdisc
#> [1] "Absolute Bioavailability"
#>
#>
#> $mrt.last
#> $mrt.last$FUN
#> [1] "pk.calc.mrt"
#>
#> $mrt.last$values
#> [1] FALSE TRUE
#>
#> $mrt.last$unit_type
#> [1] "time"
#>
#> $mrt.last$pretty_name
#> [1] "MRT (based on AUClast)"
#>
#> $mrt.last$desc
#> [1] "The mean residence time to the last observed concentration above the LOQ"
#>
#> $mrt.last$sparse
#> [1] FALSE
#>
#> $mrt.last$formalsmap
#> $mrt.last$formalsmap$auc
#> [1] "auclast"
#>
#> $mrt.last$formalsmap$aumc
#> [1] "aumclast"
#>
#>
#> $mrt.last$depends
#> [1] "auclast" "aumclast"
#>
#> $mrt.last$datatype
#> [1] "interval"
#>
#> $mrt.last$pptestcd_cdisc
#> $mrt.last$pptestcd_cdisc$route
#> $mrt.last$pptestcd_cdisc$route$extravascular
#> [1] "MRTEVLST"
#>
#> $mrt.last$pptestcd_cdisc$route$intravascular
#> [1] "MRTICLST"
#>
#>
#>
#> $mrt.last$pptest_cdisc
#> $mrt.last$pptest_cdisc$route
#> $mrt.last$pptest_cdisc$route$extravascular
#> [1] "MRT Extravasc to Last Nonzero Conc"
#>
#> $mrt.last$pptest_cdisc$route$intravascular
#> [1] "MRT IV Cont Inf to Last Nonzero Conc"
#>
#>
#>
#>
#> $mrt.all
#> $mrt.all$FUN
#> [1] "pk.calc.mrt"
#>
#> $mrt.all$values
#> [1] FALSE TRUE
#>
#> $mrt.all$unit_type
#> [1] "time"
#>
#> $mrt.all$pretty_name
#> [1] "MRT (based on AUCall)"
#>
#> $mrt.all$desc
#> [1] "Mean residence time calculated with AUCall/AUMCall"
#>
#> $mrt.all$sparse
#> [1] FALSE
#>
#> $mrt.all$formalsmap
#> $mrt.all$formalsmap$auc
#> [1] "aucall"
#>
#> $mrt.all$formalsmap$aumc
#> [1] "aumcall"
#>
#>
#> $mrt.all$depends
#> [1] "aucall" "aumcall"
#>
#> $mrt.all$datatype
#> [1] "interval"
#>
#> $mrt.all$pptestcd_cdisc
#> [1] "mrt.all"
#>
#> $mrt.all$pptest_cdisc
#> [1] "Mean residence time calculated with AUCall/AUMCall"
#>
#>
#> $mrt.int.all
#> $mrt.int.all$FUN
#> [1] "pk.calc.mrt"
#>
#> $mrt.int.all$values
#> [1] FALSE TRUE
#>
#> $mrt.int.all$unit_type
#> [1] "time"
#>
#> $mrt.int.all$pretty_name
#> [1] "MRT (based on AUCint.all)"
#>
#> $mrt.int.all$desc
#> [1] "Mean residence time over interval calculated with AUCint.all/AUMCint.all"
#>
#> $mrt.int.all$sparse
#> [1] FALSE
#>
#> $mrt.int.all$formalsmap
#> $mrt.int.all$formalsmap$auc
#> [1] "aucint.all"
#>
#> $mrt.int.all$formalsmap$aumc
#> [1] "aumcint.all"
#>
#>
#> $mrt.int.all$depends
#> [1] "aucint.all" "aumcint.all"
#>
#> $mrt.int.all$datatype
#> [1] "interval"
#>
#> $mrt.int.all$pptestcd_cdisc
#> [1] "mrt.int.all"
#>
#> $mrt.int.all$pptest_cdisc
#> [1] "Mean residence time over interval calculated with AUCint.all/AUMCint.all"
#>
#>
#> $mrt.int.last
#> $mrt.int.last$FUN
#> [1] "pk.calc.mrt"
#>
#> $mrt.int.last$values
#> [1] FALSE TRUE
#>
#> $mrt.int.last$unit_type
#> [1] "time"
#>
#> $mrt.int.last$pretty_name
#> [1] "MRT (based on AUCint.last)"
#>
#> $mrt.int.last$desc
#> [1] "Mean residence time over interval calculated with AUCint.last/AUMCint.last"
#>
#> $mrt.int.last$sparse
#> [1] FALSE
#>
#> $mrt.int.last$formalsmap
#> $mrt.int.last$formalsmap$auc
#> [1] "aucint.last"
#>
#> $mrt.int.last$formalsmap$aumc
#> [1] "aumcint.last"
#>
#>
#> $mrt.int.last$depends
#> [1] "aucint.last" "aumcint.last"
#>
#> $mrt.int.last$datatype
#> [1] "interval"
#>
#> $mrt.int.last$pptestcd_cdisc
#> [1] "mrt.int.last"
#>
#> $mrt.int.last$pptest_cdisc
#> [1] "Mean residence time over interval calculated with AUCint.last/AUMCint.last"
#>
#>
#> $mrt.iv.last
#> $mrt.iv.last$FUN
#> [1] "pk.calc.mrt.iv"
#>
#> $mrt.iv.last$values
#> [1] FALSE TRUE
#>
#> $mrt.iv.last$unit_type
#> [1] "time"
#>
#> $mrt.iv.last$pretty_name
#> [1] "MRT (for IV dosing, based on AUClast)"
#>
#> $mrt.iv.last$desc
#> [1] "The mean residence time to the last observed concentration above the LOQ correcting for dosing duration"
#>
#> $mrt.iv.last$sparse
#> [1] FALSE
#>
#> $mrt.iv.last$formalsmap
#> $mrt.iv.last$formalsmap$auc
#> [1] "auclast"
#>
#> $mrt.iv.last$formalsmap$aumc
#> [1] "aumclast"
#>
#>
#> $mrt.iv.last$depends
#> [1] "auclast" "aumclast"
#>
#> $mrt.iv.last$datatype
#> [1] "interval"
#>
#> $mrt.iv.last$pptestcd_cdisc
#> [1] "MRTIBLST"
#>
#> $mrt.iv.last$pptest_cdisc
#> [1] "MRT Intravasc to Last Nonzero Conc"
#>
#>
#> $vss.last
#> $vss.last$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.last$values
#> [1] FALSE TRUE
#>
#> $vss.last$unit_type
#> [1] "volume"
#>
#> $vss.last$pretty_name
#> [1] "Vss (based on AUClast)"
#>
#> $vss.last$desc
#> [1] "The steady-state volume of distribution calculating through Tlast"
#>
#> $vss.last$sparse
#> [1] FALSE
#>
#> $vss.last$formalsmap
#> $vss.last$formalsmap$cl
#> [1] "cl.last"
#>
#> $vss.last$formalsmap$mrt
#> [1] "mrt.last"
#>
#>
#> $vss.last$depends
#> [1] "cl.last" "mrt.last"
#>
#> $vss.last$datatype
#> [1] "interval"
#>
#> $vss.last$pptestcd_cdisc
#> $vss.last$pptestcd_cdisc$route
#> $vss.last$pptestcd_cdisc$route$extravascular
#> [1] "VSSF/FLST"
#>
#> $vss.last$pptestcd_cdisc$route$intravascular
#> [1] "VSSLST"
#>
#>
#>
#> $vss.last$pptest_cdisc
#> $vss.last$pptest_cdisc$route
#> $vss.last$pptest_cdisc$route$extravascular
#> [1] "Vss by F (based on AUClast)"
#>
#> $vss.last$pptest_cdisc$route$intravascular
#> [1] "Vss (based on AUClast)"
#>
#>
#>
#>
#> $vss.iv.last
#> $vss.iv.last$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.iv.last$values
#> [1] FALSE TRUE
#>
#> $vss.iv.last$unit_type
#> [1] "volume"
#>
#> $vss.iv.last$pretty_name
#> [1] "Vss (for IV dosing, based on AUClast)"
#>
#> $vss.iv.last$desc
#> [1] "The steady-state volume of distribution with intravenous infusion calculating through Tlast"
#>
#> $vss.iv.last$sparse
#> [1] FALSE
#>
#> $vss.iv.last$formalsmap
#> $vss.iv.last$formalsmap$cl
#> [1] "cl.last"
#>
#> $vss.iv.last$formalsmap$mrt
#> [1] "mrt.iv.last"
#>
#>
#> $vss.iv.last$depends
#> [1] "cl.last" "mrt.iv.last"
#>
#> $vss.iv.last$datatype
#> [1] "interval"
#>
#> $vss.iv.last$pptestcd_cdisc
#> [1] "VSSIVLST"
#>
#> $vss.iv.last$pptest_cdisc
#> [1] "Vss (for IV dosing, based on AUClast)"
#>
#>
#> $vss.all
#> $vss.all$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.all$values
#> [1] FALSE TRUE
#>
#> $vss.all$unit_type
#> [1] "volume"
#>
#> $vss.all$pretty_name
#> [1] "Vss (based on AUCall)"
#>
#> $vss.all$desc
#> [1] "Steady-state volume of distribution calculated with AUCall-based CL and MRT"
#>
#> $vss.all$sparse
#> [1] FALSE
#>
#> $vss.all$formalsmap
#> $vss.all$formalsmap$cl
#> [1] "cl.all"
#>
#> $vss.all$formalsmap$mrt
#> [1] "mrt.all"
#>
#>
#> $vss.all$depends
#> [1] "cl.all" "mrt.all"
#>
#> $vss.all$datatype
#> [1] "interval"
#>
#> $vss.all$pptestcd_cdisc
#> [1] "vss.all"
#>
#> $vss.all$pptest_cdisc
#> [1] "Steady-state volume of distribution calculated with AUCall-based CL and MRT"
#>
#>
#> $vss.int.all
#> $vss.int.all$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.int.all$values
#> [1] FALSE TRUE
#>
#> $vss.int.all$unit_type
#> [1] "volume"
#>
#> $vss.int.all$pretty_name
#> [1] "Vss (based on AUCint.all)"
#>
#> $vss.int.all$desc
#> [1] "Steady-state volume of distribution using interval AUCint.all"
#>
#> $vss.int.all$sparse
#> [1] FALSE
#>
#> $vss.int.all$formalsmap
#> $vss.int.all$formalsmap$cl
#> [1] "cl.int.all"
#>
#> $vss.int.all$formalsmap$mrt
#> [1] "mrt.int.all"
#>
#>
#> $vss.int.all$depends
#> [1] "cl.int.all" "mrt.int.all"
#>
#> $vss.int.all$datatype
#> [1] "interval"
#>
#> $vss.int.all$pptestcd_cdisc
#> [1] "vss.int.all"
#>
#> $vss.int.all$pptest_cdisc
#> [1] "Steady-state volume of distribution using interval AUCint.all"
#>
#>
#> $vss.int.last
#> $vss.int.last$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.int.last$values
#> [1] FALSE TRUE
#>
#> $vss.int.last$unit_type
#> [1] "volume"
#>
#> $vss.int.last$pretty_name
#> [1] "Vss (based on AUCint.last)"
#>
#> $vss.int.last$desc
#> [1] "Steady-state volume of distribution using interval AUCint.last"
#>
#> $vss.int.last$sparse
#> [1] FALSE
#>
#> $vss.int.last$formalsmap
#> $vss.int.last$formalsmap$cl
#> [1] "cl.int.last"
#>
#> $vss.int.last$formalsmap$mrt
#> [1] "mrt.int.last"
#>
#>
#> $vss.int.last$depends
#> [1] "cl.int.last" "mrt.int.last"
#>
#> $vss.int.last$datatype
#> [1] "interval"
#>
#> $vss.int.last$pptestcd_cdisc
#> [1] "vss.int.last"
#>
#> $vss.int.last$pptest_cdisc
#> [1] "Steady-state volume of distribution using interval AUCint.last"
#>
#>
#> $cav
#> $cav$FUN
#> [1] "pk.calc.cav"
#>
#> $cav$values
#> [1] FALSE TRUE
#>
#> $cav$unit_type
#> [1] "conc"
#>
#> $cav$pretty_name
#> [1] "Cav"
#>
#> $cav$desc
#> [1] "The average concentration during an interval (calculated with AUClast)"
#>
#> $cav$sparse
#> [1] FALSE
#>
#> $cav$formalsmap
#> $cav$formalsmap$auc
#> [1] "auclast"
#>
#>
#> $cav$depends
#> [1] "auclast"
#>
#> $cav$datatype
#> [1] "interval"
#>
#> $cav$pptestcd_cdisc
#> [1] "CAVG"
#>
#> $cav$pptest_cdisc
#> [1] "Average Conc"
#>
#>
#> $cav.int.last
#> $cav.int.last$FUN
#> [1] "pk.calc.cav"
#>
#> $cav.int.last$values
#> [1] FALSE TRUE
#>
#> $cav.int.last$unit_type
#> [1] "conc"
#>
#> $cav.int.last$pretty_name
#> [1] "Cav"
#>
#> $cav.int.last$desc
#> [1] "The average concentration during an interval (calculated with AUCint.last)"
#>
#> $cav.int.last$sparse
#> [1] FALSE
#>
#> $cav.int.last$formalsmap
#> $cav.int.last$formalsmap$auc
#> [1] "aucint.last"
#>
#>
#> $cav.int.last$depends
#> [1] "aucint.last"
#>
#> $cav.int.last$datatype
#> [1] "interval"
#>
#> $cav.int.last$pptestcd_cdisc
#> [1] "CAVGINT"
#>
#> $cav.int.last$pptest_cdisc
#> [1] "Average Conc from T1 to T2"
#>
#>
#> $cav.int.all
#> $cav.int.all$FUN
#> [1] "pk.calc.cav"
#>
#> $cav.int.all$values
#> [1] FALSE TRUE
#>
#> $cav.int.all$unit_type
#> [1] "conc"
#>
#> $cav.int.all$pretty_name
#> [1] "Cav"
#>
#> $cav.int.all$desc
#> [1] "The average concentration during an interval (calculated with AUCint.all)"
#>
#> $cav.int.all$sparse
#> [1] FALSE
#>
#> $cav.int.all$formalsmap
#> $cav.int.all$formalsmap$auc
#> [1] "aucint.all"
#>
#>
#> $cav.int.all$depends
#> [1] "aucint.all"
#>
#> $cav.int.all$datatype
#> [1] "interval"
#>
#> $cav.int.all$pptestcd_cdisc
#> [1] "CAVGINA"
#>
#> $cav.int.all$pptest_cdisc
#> [1] "Cavg All"
#>
#>
#> $ctrough
#> $ctrough$FUN
#> [1] "pk.calc.ctrough"
#>
#> $ctrough$values
#> [1] FALSE TRUE
#>
#> $ctrough$unit_type
#> [1] "conc"
#>
#> $ctrough$pretty_name
#> [1] "Ctrough"
#>
#> $ctrough$desc
#> [1] "The trough (end of interval) concentration"
#>
#> $ctrough$sparse
#> [1] FALSE
#>
#> $ctrough$formalsmap
#> list()
#>
#> $ctrough$depends
#> NULL
#>
#> $ctrough$datatype
#> [1] "interval"
#>
#> $ctrough$pptestcd_cdisc
#> [1] "CTROUGH"
#>
#> $ctrough$pptest_cdisc
#> [1] "Conc Trough"
#>
#>
#> $cstart
#> $cstart$FUN
#> [1] "pk.calc.cstart"
#>
#> $cstart$values
#> [1] FALSE TRUE
#>
#> $cstart$unit_type
#> [1] "conc"
#>
#> $cstart$pretty_name
#> [1] "Cstart"
#>
#> $cstart$desc
#> [1] "The predose concentration"
#>
#> $cstart$sparse
#> [1] FALSE
#>
#> $cstart$formalsmap
#> list()
#>
#> $cstart$depends
#> NULL
#>
#> $cstart$datatype
#> [1] "interval"
#>
#> $cstart$pptestcd_cdisc
#> [1] "CSTART"
#>
#> $cstart$pptest_cdisc
#> [1] "Cstart"
#>
#>
#> $ptr
#> $ptr$FUN
#> [1] "pk.calc.ptr"
#>
#> $ptr$values
#> [1] FALSE TRUE
#>
#> $ptr$unit_type
#> [1] "fraction"
#>
#> $ptr$pretty_name
#> [1] "Peak-to-trough ratio"
#>
#> $ptr$desc
#> [1] "Peak-to-Trough ratio (fraction)"
#>
#> $ptr$sparse
#> [1] FALSE
#>
#> $ptr$formalsmap
#> list()
#>
#> $ptr$depends
#> [1] "cmax" "ctrough"
#>
#> $ptr$datatype
#> [1] "interval"
#>
#> $ptr$pptestcd_cdisc
#> [1] "PTROUGHR"
#>
#> $ptr$pptest_cdisc
#> [1] "Peak Trough Ratio"
#>
#>
#> $tlag
#> $tlag$FUN
#> [1] "pk.calc.tlag"
#>
#> $tlag$values
#> [1] FALSE TRUE
#>
#> $tlag$unit_type
#> [1] "time"
#>
#> $tlag$pretty_name
#> [1] "Tlag"
#>
#> $tlag$desc
#> [1] "Lag time"
#>
#> $tlag$sparse
#> [1] FALSE
#>
#> $tlag$formalsmap
#> list()
#>
#> $tlag$depends
#> NULL
#>
#> $tlag$datatype
#> [1] "interval"
#>
#> $tlag$pptestcd_cdisc
#> [1] "TLAG"
#>
#> $tlag$pptest_cdisc
#> [1] "Time to First Nonzero Conc"
#>
#>
#> $deg.fluc
#> $deg.fluc$FUN
#> [1] "pk.calc.deg.fluc"
#>
#> $deg.fluc$values
#> [1] FALSE TRUE
#>
#> $deg.fluc$unit_type
#> [1] "%"
#>
#> $deg.fluc$pretty_name
#> [1] "Degree of fluctuation"
#>
#> $deg.fluc$desc
#> [1] "Degree of fluctuation"
#>
#> $deg.fluc$sparse
#> [1] FALSE
#>
#> $deg.fluc$formalsmap
#> list()
#>
#> $deg.fluc$depends
#> [1] "cmax" "cmin" "cav"
#>
#> $deg.fluc$datatype
#> [1] "interval"
#>
#> $deg.fluc$pptestcd_cdisc
#> [1] "DEGFLUC"
#>
#> $deg.fluc$pptest_cdisc
#> [1] "Degree of fluctuation"
#>
#>
#> $swing
#> $swing$FUN
#> [1] "pk.calc.swing"
#>
#> $swing$values
#> [1] FALSE TRUE
#>
#> $swing$unit_type
#> [1] "%"
#>
#> $swing$pretty_name
#> [1] "Swing"
#>
#> $swing$desc
#> [1] "Swing relative to Cmin"
#>
#> $swing$sparse
#> [1] FALSE
#>
#> $swing$formalsmap
#> list()
#>
#> $swing$depends
#> [1] "cmax" "cmin"
#>
#> $swing$datatype
#> [1] "interval"
#>
#> $swing$pptestcd_cdisc
#> [1] "SWING"
#>
#> $swing$pptest_cdisc
#> [1] "Swing"
#>
#>
#> $ceoi
#> $ceoi$FUN
#> [1] "pk.calc.ceoi"
#>
#> $ceoi$values
#> [1] FALSE TRUE
#>
#> $ceoi$unit_type
#> [1] "conc"
#>
#> $ceoi$pretty_name
#> [1] "Ceoi"
#>
#> $ceoi$desc
#> [1] "Concentration at the end of infusion"
#>
#> $ceoi$sparse
#> [1] FALSE
#>
#> $ceoi$formalsmap
#> list()
#>
#> $ceoi$depends
#> NULL
#>
#> $ceoi$datatype
#> [1] "interval"
#>
#> $ceoi$pptestcd_cdisc
#> [1] "CEOI"
#>
#> $ceoi$pptest_cdisc
#> [1] "Ceoi"
#>
#>
#> $aucabove.predose.all
#> $aucabove.predose.all$FUN
#> [1] "pk.calc.aucabove"
#>
#> $aucabove.predose.all$values
#> [1] FALSE TRUE
#>
#> $aucabove.predose.all$unit_type
#> [1] "auc"
#>
#> $aucabove.predose.all$pretty_name
#> [1] "AUC,above"
#>
#> $aucabove.predose.all$desc
#> [1] "The area under the concentration time the beginning of the interval to the last concentration above the limit of quantification plus the triangle from that last concentration to 0 at the first concentration below the limit of quantification, with a concentration subtracted from all concentrations and values below zero after subtraction set to zero"
#>
#> $aucabove.predose.all$sparse
#> [1] FALSE
#>
#> $aucabove.predose.all$formalsmap
#> $aucabove.predose.all$formalsmap$conc_above
#> [1] "cstart"
#>
#>
#> $aucabove.predose.all$depends
#> [1] "cstart"
#>
#> $aucabove.predose.all$datatype
#> [1] "interval"
#>
#> $aucabove.predose.all$pptestcd_cdisc
#> [1] "AUCABVPA"
#>
#> $aucabove.predose.all$pptest_cdisc
#> [1] "AUC above predose"
#>
#>
#> $aucabove.trough.all
#> $aucabove.trough.all$FUN
#> [1] "pk.calc.aucabove"
#>
#> $aucabove.trough.all$values
#> [1] FALSE TRUE
#>
#> $aucabove.trough.all$unit_type
#> [1] "auc"
#>
#> $aucabove.trough.all$pretty_name
#> [1] "AUC,above"
#>
#> $aucabove.trough.all$desc
#> [1] "The area under the concentration time the beginning of the interval to the last concentration above the limit of quantification plus the triangle from that last concentration to 0 at the first concentration below the limit of quantification, with a concentration subtracted from all concentrations and values below zero after subtraction set to zero"
#>
#> $aucabove.trough.all$sparse
#> [1] FALSE
#>
#> $aucabove.trough.all$formalsmap
#> $aucabove.trough.all$formalsmap$conc_above
#> [1] "ctrough"
#>
#>
#> $aucabove.trough.all$depends
#> [1] "ctrough"
#>
#> $aucabove.trough.all$datatype
#> [1] "interval"
#>
#> $aucabove.trough.all$pptestcd_cdisc
#> [1] "AUCABVTA"
#>
#> $aucabove.trough.all$pptest_cdisc
#> [1] "AUC above trough"
#>
#>
#> $count_conc
#> $count_conc$FUN
#> [1] "pk.calc.count_conc"
#>
#> $count_conc$values
#> [1] FALSE TRUE
#>
#> $count_conc$unit_type
#> [1] "count"
#>
#> $count_conc$pretty_name
#> [1] "Concentration count"
#>
#> $count_conc$desc
#> [1] "Number of non-missing concentrations for an interval"
#>
#> $count_conc$sparse
#> [1] FALSE
#>
#> $count_conc$formalsmap
#> list()
#>
#> $count_conc$depends
#> NULL
#>
#> $count_conc$datatype
#> [1] "interval"
#>
#> $count_conc$pptestcd_cdisc
#> [1] "CNTCONC"
#>
#> $count_conc$pptest_cdisc
#> [1] "Concentration count"
#>
#>
#> $count_conc_measured
#> $count_conc_measured$FUN
#> [1] "pk.calc.count_conc_measured"
#>
#> $count_conc_measured$values
#> [1] FALSE TRUE
#>
#> $count_conc_measured$unit_type
#> [1] "count"
#>
#> $count_conc_measured$pretty_name
#> [1] "Measured concentration count"
#>
#> $count_conc_measured$desc
#> [1] "Number of measured and non BLQ/ALQ concentrations for an interval"
#>
#> $count_conc_measured$sparse
#> [1] FALSE
#>
#> $count_conc_measured$formalsmap
#> list()
#>
#> $count_conc_measured$depends
#> NULL
#>
#> $count_conc_measured$datatype
#> [1] "interval"
#>
#> $count_conc_measured$pptestcd_cdisc
#> [1] "count_conc_measured"
#>
#> $count_conc_measured$pptest_cdisc
#> [1] "Number of measured and non BLQ/ALQ concentrations for an interval"
#>
#>
#> $totdose
#> $totdose$FUN
#> [1] "pk.calc.totdose"
#>
#> $totdose$values
#> [1] FALSE TRUE
#>
#> $totdose$unit_type
#> [1] "dose"
#>
#> $totdose$pretty_name
#> [1] "Total dose"
#>
#> $totdose$desc
#> [1] "Total dose administered during an interval"
#>
#> $totdose$sparse
#> [1] FALSE
#>
#> $totdose$formalsmap
#> list()
#>
#> $totdose$depends
#> NULL
#>
#> $totdose$datatype
#> [1] "interval"
#>
#> $totdose$pptestcd_cdisc
#> [1] "TDOSE"
#>
#> $totdose$pptest_cdisc
#> [1] "Total dose administered"
#>
#>
#> $volpk
#> $volpk$FUN
#> [1] "pk.calc.volpk"
#>
#> $volpk$values
#> [1] FALSE TRUE
#>
#> $volpk$unit_type
#> [1] "volume"
#>
#> $volpk$pretty_name
#> [1] "Total Urine Volume"
#>
#> $volpk$desc
#> [1] "The sum of urine volumes for the interval"
#>
#> $volpk$sparse
#> [1] FALSE
#>
#> $volpk$formalsmap
#> list()
#>
#> $volpk$depends
#> NULL
#>
#> $volpk$datatype
#> [1] "interval"
#>
#> $volpk$pptestcd_cdisc
#> [1] "VOLPK"
#>
#> $volpk$pptest_cdisc
#> [1] "Volume of PK sample"
#>
#>
#> $ae
#> $ae$FUN
#> [1] "pk.calc.ae"
#>
#> $ae$values
#> [1] FALSE TRUE
#>
#> $ae$unit_type
#> [1] "amount"
#>
#> $ae$pretty_name
#> [1] "Amount excreted"
#>
#> $ae$desc
#> [1] "The amount excreted (typically into urine or feces)"
#>
#> $ae$sparse
#> [1] FALSE
#>
#> $ae$formalsmap
#> list()
#>
#> $ae$depends
#> NULL
#>
#> $ae$datatype
#> [1] "interval"
#>
#> $ae$pptestcd_cdisc
#> [1] "RCAMINT"
#>
#> $ae$pptest_cdisc
#> [1] "Amt Rec from T1 to T2"
#>
#>
#> $clr.last
#> $clr.last$FUN
#> [1] "pk.calc.clr"
#>
#> $clr.last$values
#> [1] FALSE TRUE
#>
#> $clr.last$unit_type
#> [1] "renal_clearance"
#>
#> $clr.last$pretty_name
#> [1] "Renal clearance (from AUClast)"
#>
#> $clr.last$desc
#> [1] "The renal clearance calculated using AUClast"
#>
#> $clr.last$sparse
#> [1] FALSE
#>
#> $clr.last$formalsmap
#> $clr.last$formalsmap$auc
#> [1] "auclast"
#>
#>
#> $clr.last$depends
#> [1] "ae"
#>
#> $clr.last$datatype
#> [1] "interval"
#>
#> $clr.last$pptestcd_cdisc
#> [1] "RENALCL"
#>
#> $clr.last$pptest_cdisc
#> [1] "Renal CL"
#>
#>
#> $clr.obs
#> $clr.obs$FUN
#> [1] "pk.calc.clr"
#>
#> $clr.obs$values
#> [1] FALSE TRUE
#>
#> $clr.obs$unit_type
#> [1] "renal_clearance"
#>
#> $clr.obs$pretty_name
#> [1] "Renal clearance (from AUCinf,obs)"
#>
#> $clr.obs$desc
#> [1] "The renal clearance calculated using AUCinf,obs"
#>
#> $clr.obs$sparse
#> [1] FALSE
#>
#> $clr.obs$formalsmap
#> $clr.obs$formalsmap$auc
#> [1] "aucinf.obs"
#>
#>
#> $clr.obs$depends
#> [1] "ae"
#>
#> $clr.obs$datatype
#> [1] "interval"
#>
#> $clr.obs$pptestcd_cdisc
#> [1] "RENALCL"
#>
#> $clr.obs$pptest_cdisc
#> [1] "Renal CL"
#>
#>
#> $clr.pred
#> $clr.pred$FUN
#> [1] "pk.calc.clr"
#>
#> $clr.pred$values
#> [1] FALSE TRUE
#>
#> $clr.pred$unit_type
#> [1] "renal_clearance"
#>
#> $clr.pred$pretty_name
#> [1] "Renal clearance (from AUCinf,pred)"
#>
#> $clr.pred$desc
#> [1] "The renal clearance calculated using AUCinf,pred"
#>
#> $clr.pred$sparse
#> [1] FALSE
#>
#> $clr.pred$formalsmap
#> $clr.pred$formalsmap$auc
#> [1] "aucinf.pred"
#>
#>
#> $clr.pred$depends
#> [1] "ae"
#>
#> $clr.pred$datatype
#> [1] "interval"
#>
#> $clr.pred$pptestcd_cdisc
#> [1] "RENALCL"
#>
#> $clr.pred$pptest_cdisc
#> [1] "Renal CL"
#>
#>
#> $fe
#> $fe$FUN
#> [1] "pk.calc.fe"
#>
#> $fe$values
#> [1] FALSE TRUE
#>
#> $fe$unit_type
#> [1] "amount_dose"
#>
#> $fe$pretty_name
#> [1] "Fraction excreted"
#>
#> $fe$desc
#> [1] "The fraction of the dose excreted"
#>
#> $fe$sparse
#> [1] FALSE
#>
#> $fe$formalsmap
#> list()
#>
#> $fe$depends
#> [1] "ae"
#>
#> $fe$datatype
#> [1] "interval"
#>
#> $fe$pptestcd_cdisc
#> [1] "FREXINT"
#>
#> $fe$pptest_cdisc
#> [1] "Fract Excr from T1 to T2"
#>
#>
#> $ertlst
#> $ertlst$FUN
#> [1] "pk.calc.ertlst"
#>
#> $ertlst$values
#> [1] FALSE TRUE
#>
#> $ertlst$unit_type
#> [1] "time"
#>
#> $ertlst$pretty_name
#> [1] "Tlast excretion rate"
#>
#> $ertlst$desc
#> [1] "The midpoint collection time of the last measurable excretion rate (typically in urine or feces)"
#>
#> $ertlst$sparse
#> [1] FALSE
#>
#> $ertlst$formalsmap
#> list()
#>
#> $ertlst$depends
#> NULL
#>
#> $ertlst$datatype
#> [1] "interval"
#>
#> $ertlst$pptestcd_cdisc
#> [1] "ERTLST"
#>
#> $ertlst$pptest_cdisc
#> [1] "Time of Last Excretion Rate"
#>
#>
#> $ermax
#> $ermax$FUN
#> [1] "pk.calc.ermax"
#>
#> $ermax$values
#> [1] FALSE TRUE
#>
#> $ermax$unit_type
#> [1] "amount_time"
#>
#> $ermax$pretty_name
#> [1] "Maximum excretion rate"
#>
#> $ermax$desc
#> [1] "The maximum excretion rate (typically in urine or feces)"
#>
#> $ermax$sparse
#> [1] FALSE
#>
#> $ermax$formalsmap
#> list()
#>
#> $ermax$depends
#> NULL
#>
#> $ermax$datatype
#> [1] "interval"
#>
#> $ermax$pptestcd_cdisc
#> [1] "ERMAX"
#>
#> $ermax$pptest_cdisc
#> [1] "Max Excretion Rate"
#>
#>
#> $ertmax
#> $ertmax$FUN
#> [1] "pk.calc.ertmax"
#>
#> $ertmax$values
#> [1] FALSE TRUE
#>
#> $ertmax$unit_type
#> [1] "time"
#>
#> $ertmax$pretty_name
#> [1] "Tmax excretion rate"
#>
#> $ertmax$desc
#> [1] "The midpoint collection time of the maximum excretion rate (typically in urine or feces)"
#>
#> $ertmax$sparse
#> [1] FALSE
#>
#> $ertmax$formalsmap
#> list()
#>
#> $ertmax$depends
#> NULL
#>
#> $ertmax$datatype
#> [1] "interval"
#>
#> $ertmax$pptestcd_cdisc
#> [1] "ERTMAX"
#>
#> $ertmax$pptest_cdisc
#> [1] "Midpoint of Interval of Maximum ER"
#>
#>
#> $sparse_auclast
#> $sparse_auclast$FUN
#> [1] "pk.calc.sparse_auclast"
#>
#> $sparse_auclast$values
#> [1] FALSE TRUE
#>
#> $sparse_auclast$unit_type
#> [1] "auc"
#>
#> $sparse_auclast$pretty_name
#> [1] "Sparse AUClast"
#>
#> $sparse_auclast$desc
#> [1] "For sparse PK sampling, the area under the concentration time curve from the beginning of the interval to the last concentration above the limit of quantification"
#>
#> $sparse_auclast$sparse
#> [1] TRUE
#>
#> $sparse_auclast$formalsmap
#> list()
#>
#> $sparse_auclast$depends
#> NULL
#>
#> $sparse_auclast$datatype
#> [1] "interval"
#>
#> $sparse_auclast$pptestcd_cdisc
#> [1] "SPARSEAL"
#>
#> $sparse_auclast$pptest_cdisc
#> [1] "Sparse AUClast"
#>
#>
#> $sparse_auc_se
#> $sparse_auc_se$FUN
#> [1] NA
#>
#> $sparse_auc_se$values
#> [1] FALSE TRUE
#>
#> $sparse_auc_se$unit_type
#> [1] "auc"
#>
#> $sparse_auc_se$pretty_name
#> [1] "Sparse AUClast standard error"
#>
#> $sparse_auc_se$desc
#> [1] "For sparse PK sampling, the standard error of the area under the concentration time curve from the beginning of the interval to the last concentration above the limit of quantification"
#>
#> $sparse_auc_se$sparse
#> [1] FALSE
#>
#> $sparse_auc_se$formalsmap
#> list()
#>
#> $sparse_auc_se$depends
#> [1] "sparse_auclast"
#>
#> $sparse_auc_se$datatype
#> [1] "interval"
#>
#> $sparse_auc_se$pptestcd_cdisc
#> [1] "SPARSEAS"
#>
#> $sparse_auc_se$pptest_cdisc
#> [1] "Sparse AUClast standard error"
#>
#>
#> $sparse_auc_df
#> $sparse_auc_df$FUN
#> [1] NA
#>
#> $sparse_auc_df$values
#> [1] FALSE TRUE
#>
#> $sparse_auc_df$unit_type
#> [1] "count"
#>
#> $sparse_auc_df$pretty_name
#> [1] "Sparse AUClast degrees of freedom"
#>
#> $sparse_auc_df$desc
#> [1] "For sparse PK sampling, the standard error degrees of freedom of the area under the concentration time curve from the beginning of the interval to the last concentration above the limit of quantification"
#>
#> $sparse_auc_df$sparse
#> [1] FALSE
#>
#> $sparse_auc_df$formalsmap
#> list()
#>
#> $sparse_auc_df$depends
#> [1] "sparse_auclast"
#>
#> $sparse_auc_df$datatype
#> [1] "interval"
#>
#> $sparse_auc_df$pptestcd_cdisc
#> [1] "SPARSEAD"
#>
#> $sparse_auc_df$pptest_cdisc
#> [1] "Sparse AUClast degrees of freedom"
#>
#>
#> $sparse_aumclast
#> $sparse_aumclast$FUN
#> [1] "pk.calc.sparse_aumclast"
#>
#> $sparse_aumclast$values
#> [1] FALSE TRUE
#>
#> $sparse_aumclast$unit_type
#> [1] "aumc"
#>
#> $sparse_aumclast$pretty_name
#> [1] "Sparse AUMClast"
#>
#> $sparse_aumclast$desc
#> [1] "For sparse PK sampling, the area under the moment curve from the beginning of the interval to the last concentration above the limit of quantification"
#>
#> $sparse_aumclast$sparse
#> [1] TRUE
#>
#> $sparse_aumclast$formalsmap
#> list()
#>
#> $sparse_aumclast$depends
#> [1] "sparse_auclast"
#>
#> $sparse_aumclast$datatype
#> [1] "interval"
#>
#> $sparse_aumclast$pptestcd_cdisc
#> [1] "sparse_aumclast"
#>
#> $sparse_aumclast$pptest_cdisc
#> [1] "For sparse PK sampling, the area under the moment curve from the beginning of the interval to the last concentration above the limit of quantification"
#>
#>
#> $sparse_aumc_se
#> $sparse_aumc_se$FUN
#> [1] NA
#>
#> $sparse_aumc_se$values
#> [1] FALSE TRUE
#>
#> $sparse_aumc_se$unit_type
#> [1] "aumc"
#>
#> $sparse_aumc_se$pretty_name
#> [1] "Sparse AUMC standard error"
#>
#> $sparse_aumc_se$desc
#> [1] "For sparse PK sampling, the standard error of the area under the moment curve"
#>
#> $sparse_aumc_se$sparse
#> [1] FALSE
#>
#> $sparse_aumc_se$formalsmap
#> list()
#>
#> $sparse_aumc_se$depends
#> [1] "sparse_aumclast"
#>
#> $sparse_aumc_se$datatype
#> [1] "interval"
#>
#> $sparse_aumc_se$pptestcd_cdisc
#> [1] "sparse_aumc_se"
#>
#> $sparse_aumc_se$pptest_cdisc
#> [1] "For sparse PK sampling, the standard error of the area under the moment curve"
#>
#>
#> $sparse_aumc_df
#> $sparse_aumc_df$FUN
#> [1] NA
#>
#> $sparse_aumc_df$values
#> [1] FALSE TRUE
#>
#> $sparse_aumc_df$unit_type
#> [1] "count"
#>
#> $sparse_aumc_df$pretty_name
#> [1] "Sparse AUMC degrees of freedom"
#>
#> $sparse_aumc_df$desc
#> [1] "For sparse PK sampling, the degrees of freedom for the AUMC variance estimate"
#>
#> $sparse_aumc_df$sparse
#> [1] FALSE
#>
#> $sparse_aumc_df$formalsmap
#> list()
#>
#> $sparse_aumc_df$depends
#> [1] "sparse_aumclast"
#>
#> $sparse_aumc_df$datatype
#> [1] "interval"
#>
#> $sparse_aumc_df$pptestcd_cdisc
#> [1] "sparse_aumc_df"
#>
#> $sparse_aumc_df$pptest_cdisc
#> [1] "For sparse PK sampling, the degrees of freedom for the AUMC variance estimate"
#>
#>
#> $time_above
#> $time_above$FUN
#> [1] "pk.calc.time_above"
#>
#> $time_above$values
#> [1] FALSE TRUE
#>
#> $time_above$unit_type
#> [1] "time"
#>
#> $time_above$pretty_name
#> [1] "Time above Concentration"
#>
#> $time_above$desc
#> [1] "Time above a given concentration"
#>
#> $time_above$sparse
#> [1] FALSE
#>
#> $time_above$formalsmap
#> list()
#>
#> $time_above$depends
#> NULL
#>
#> $time_above$datatype
#> [1] "interval"
#>
#> $time_above$pptestcd_cdisc
#> [1] "TAT"
#>
#> $time_above$pptest_cdisc
#> [1] "Time Above Threshold"
#>
#>
#> $aucivlast
#> $aucivlast$FUN
#> [1] "pk.calc.auciv"
#>
#> $aucivlast$values
#> [1] FALSE TRUE
#>
#> $aucivlast$unit_type
#> [1] "auc"
#>
#> $aucivlast$pretty_name
#> [1] "AUClast (IV dosing)"
#>
#> $aucivlast$desc
#> [1] "The AUClast calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#>
#> $aucivlast$sparse
#> [1] FALSE
#>
#> $aucivlast$formalsmap
#> $aucivlast$formalsmap$auc
#> [1] "auclast"
#>
#>
#> $aucivlast$depends
#> [1] "auclast" "c0"
#>
#> $aucivlast$datatype
#> [1] "interval"
#>
#> $aucivlast$pptestcd_cdisc
#> [1] "AUCIVLST"
#>
#> $aucivlast$pptest_cdisc
#> [1] "AUClast (IV dosing)"
#>
#>
#> $aucivall
#> $aucivall$FUN
#> [1] "pk.calc.auciv"
#>
#> $aucivall$values
#> [1] FALSE TRUE
#>
#> $aucivall$unit_type
#> [1] "auc"
#>
#> $aucivall$pretty_name
#> [1] "AUCall (IV dosing)"
#>
#> $aucivall$desc
#> [1] "The AUCall calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#>
#> $aucivall$sparse
#> [1] FALSE
#>
#> $aucivall$formalsmap
#> $aucivall$formalsmap$auc
#> [1] "aucall"
#>
#>
#> $aucivall$depends
#> [1] "aucall" "c0"
#>
#> $aucivall$datatype
#> [1] "interval"
#>
#> $aucivall$pptestcd_cdisc
#> [1] "AUCIVA"
#>
#> $aucivall$pptest_cdisc
#> [1] "AUCall (IV dosing)"
#>
#>
#> $aucivint.last
#> $aucivint.last$FUN
#> [1] "pk.calc.auciv"
#>
#> $aucivint.last$values
#> [1] FALSE TRUE
#>
#> $aucivint.last$unit_type
#> [1] "auc"
#>
#> $aucivint.last$pretty_name
#> [1] "AUCint,last (IV dosing)"
#>
#> $aucivint.last$desc
#> [1] "The AUCint,last calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#>
#> $aucivint.last$sparse
#> [1] FALSE
#>
#> $aucivint.last$formalsmap
#> $aucivint.last$formalsmap$auc
#> [1] "aucint.last"
#>
#>
#> $aucivint.last$depends
#> [1] "aucint.last" "c0"
#>
#> $aucivint.last$datatype
#> [1] "interval"
#>
#> $aucivint.last$pptestcd_cdisc
#> [1] "AUCIVILT"
#>
#> $aucivint.last$pptest_cdisc
#> [1] "AUCint,last (IV dosing)"
#>
#>
#> $aucivint.all
#> $aucivint.all$FUN
#> [1] "pk.calc.auciv"
#>
#> $aucivint.all$values
#> [1] FALSE TRUE
#>
#> $aucivint.all$unit_type
#> [1] "auc"
#>
#> $aucivint.all$pretty_name
#> [1] "AUCint,all (IV dosing)"
#>
#> $aucivint.all$desc
#> [1] "The AUCint,all calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#>
#> $aucivint.all$sparse
#> [1] FALSE
#>
#> $aucivint.all$formalsmap
#> $aucivint.all$formalsmap$auc
#> [1] "aucint.all"
#>
#>
#> $aucivint.all$depends
#> [1] "aucint.all" "c0"
#>
#> $aucivint.all$datatype
#> [1] "interval"
#>
#> $aucivint.all$pptestcd_cdisc
#> [1] "AUCIVINA"
#>
#> $aucivint.all$pptest_cdisc
#> [1] "AUCint,all (IV dosing)"
#>
#>
#> $aucivpbextlast
#> $aucivpbextlast$FUN
#> [1] "pk.calc.auciv_pbext"
#>
#> $aucivpbextlast$values
#> [1] FALSE TRUE
#>
#> $aucivpbextlast$unit_type
#> [1] "%"
#>
#> $aucivpbextlast$pretty_name
#> [1] "AUCbext (based on AUClast)"
#>
#> $aucivpbextlast$desc
#> [1] "The back-extrapolation percent for intravenous dosing based on AUClast"
#>
#> $aucivpbextlast$sparse
#> [1] FALSE
#>
#> $aucivpbextlast$formalsmap
#> $aucivpbextlast$formalsmap$auc
#> [1] "auclast"
#>
#> $aucivpbextlast$formalsmap$auciv
#> [1] "aucivlast"
#>
#>
#> $aucivpbextlast$depends
#> [1] "auclast" "aucivlast"
#>
#> $aucivpbextlast$datatype
#> [1] "interval"
#>
#> $aucivpbextlast$pptestcd_cdisc
#> [1] "AUCIVPLT"
#>
#> $aucivpbextlast$pptest_cdisc
#> [1] "AUCbext (based on AUClast)"
#>
#>
#> $aucivpbextall
#> $aucivpbextall$FUN
#> [1] "pk.calc.auciv_pbext"
#>
#> $aucivpbextall$values
#> [1] FALSE TRUE
#>
#> $aucivpbextall$unit_type
#> [1] "%"
#>
#> $aucivpbextall$pretty_name
#> [1] "AUCbext (based on AUCall)"
#>
#> $aucivpbextall$desc
#> [1] "The back-extrapolation percent for intravenous dosing based on AUCall"
#>
#> $aucivpbextall$sparse
#> [1] FALSE
#>
#> $aucivpbextall$formalsmap
#> $aucivpbextall$formalsmap$auc
#> [1] "aucall"
#>
#> $aucivpbextall$formalsmap$auciv
#> [1] "aucivall"
#>
#>
#> $aucivpbextall$depends
#> [1] "aucall" "aucivall"
#>
#> $aucivpbextall$datatype
#> [1] "interval"
#>
#> $aucivpbextall$pptestcd_cdisc
#> [1] "AUCIVPEA"
#>
#> $aucivpbextall$pptest_cdisc
#> [1] "AUCbext (based on AUCall)"
#>
#>
#> $aucivpbextint.last
#> $aucivpbextint.last$FUN
#> [1] "pk.calc.auciv_pbext"
#>
#> $aucivpbextint.last$values
#> [1] FALSE TRUE
#>
#> $aucivpbextint.last$unit_type
#> [1] "%"
#>
#> $aucivpbextint.last$pretty_name
#> [1] "AUCbext (based on AUCint,last)"
#>
#> $aucivpbextint.last$desc
#> [1] "The back-extrapolation percent for intravenous dosing based on AUCint,last"
#>
#> $aucivpbextint.last$sparse
#> [1] FALSE
#>
#> $aucivpbextint.last$formalsmap
#> $aucivpbextint.last$formalsmap$auc
#> [1] "aucint.last"
#>
#> $aucivpbextint.last$formalsmap$auciv
#> [1] "aucivint.last"
#>
#>
#> $aucivpbextint.last$depends
#> [1] "aucint.last" "aucivint.last"
#>
#> $aucivpbextint.last$datatype
#> [1] "interval"
#>
#> $aucivpbextint.last$pptestcd_cdisc
#> [1] "AUCIVPIL"
#>
#> $aucivpbextint.last$pptest_cdisc
#> [1] "AUCbext (based on AUCint,last)"
#>
#>
#> $aucivpbextint.all
#> $aucivpbextint.all$FUN
#> [1] "pk.calc.auciv_pbext"
#>
#> $aucivpbextint.all$values
#> [1] FALSE TRUE
#>
#> $aucivpbextint.all$unit_type
#> [1] "%"
#>
#> $aucivpbextint.all$pretty_name
#> [1] "AUCbext (based on AUCint,all)"
#>
#> $aucivpbextint.all$desc
#> [1] "The back-extrapolation percent for intravenous dosing based on AUCint,all"
#>
#> $aucivpbextint.all$sparse
#> [1] FALSE
#>
#> $aucivpbextint.all$formalsmap
#> $aucivpbextint.all$formalsmap$auc
#> [1] "aucint.all"
#>
#> $aucivpbextint.all$formalsmap$auciv
#> [1] "aucivint.all"
#>
#>
#> $aucivpbextint.all$depends
#> [1] "aucint.all" "aucivint.all"
#>
#> $aucivpbextint.all$datatype
#> [1] "interval"
#>
#> $aucivpbextint.all$pptestcd_cdisc
#> [1] "AUCIVPIA"
#>
#> $aucivpbextint.all$pptest_cdisc
#> [1] "AUCbext (based on AUCint,all)"
#>
#>
#> $aumcivlast
#> $aumcivlast$FUN
#> [1] "pk.calc.aumciv"
#>
#> $aumcivlast$values
#> [1] FALSE TRUE
#>
#> $aumcivlast$unit_type
#> [1] "aumc"
#>
#> $aumcivlast$pretty_name
#> [1] "AUMClast (IV dosing)"
#>
#> $aumcivlast$desc
#> [1] "The AUMClast calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#>
#> $aumcivlast$sparse
#> [1] FALSE
#>
#> $aumcivlast$formalsmap
#> $aumcivlast$formalsmap$aumc
#> [1] "aumclast"
#>
#>
#> $aumcivlast$depends
#> [1] "aumclast" "c0"
#>
#> $aumcivlast$datatype
#> [1] "interval"
#>
#> $aumcivlast$pptestcd_cdisc
#> [1] "aumcivlast"
#>
#> $aumcivlast$pptest_cdisc
#> [1] "The AUMClast calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#>
#>
#> $aumcivall
#> $aumcivall$FUN
#> [1] "pk.calc.aumciv"
#>
#> $aumcivall$values
#> [1] FALSE TRUE
#>
#> $aumcivall$unit_type
#> [1] "aumc"
#>
#> $aumcivall$pretty_name
#> [1] "AUMCall (IV dosing)"
#>
#> $aumcivall$desc
#> [1] "The AUMCall calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#>
#> $aumcivall$sparse
#> [1] FALSE
#>
#> $aumcivall$formalsmap
#> $aumcivall$formalsmap$aumc
#> [1] "aumcall"
#>
#>
#> $aumcivall$depends
#> [1] "aumcall" "c0"
#>
#> $aumcivall$datatype
#> [1] "interval"
#>
#> $aumcivall$pptestcd_cdisc
#> [1] "aumcivall"
#>
#> $aumcivall$pptest_cdisc
#> [1] "The AUMCall calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#>
#>
#> $aumcivint.last
#> $aumcivint.last$FUN
#> [1] "pk.calc.aumciv"
#>
#> $aumcivint.last$values
#> [1] FALSE TRUE
#>
#> $aumcivint.last$unit_type
#> [1] "aumc"
#>
#> $aumcivint.last$pretty_name
#> [1] "AUMCint,last (IV dosing)"
#>
#> $aumcivint.last$desc
#> [1] "The AUMCint,last calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#>
#> $aumcivint.last$sparse
#> [1] FALSE
#>
#> $aumcivint.last$formalsmap
#> $aumcivint.last$formalsmap$aumc
#> [1] "aumcint.last"
#>
#>
#> $aumcivint.last$depends
#> [1] "aumcint.last" "c0"
#>
#> $aumcivint.last$datatype
#> [1] "interval"
#>
#> $aumcivint.last$pptestcd_cdisc
#> [1] "aumcivint.last"
#>
#> $aumcivint.last$pptest_cdisc
#> [1] "The AUMCint,last calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#>
#>
#> $aumcivint.all
#> $aumcivint.all$FUN
#> [1] "pk.calc.aumciv"
#>
#> $aumcivint.all$values
#> [1] FALSE TRUE
#>
#> $aumcivint.all$unit_type
#> [1] "aumc"
#>
#> $aumcivint.all$pretty_name
#> [1] "AUMCint,all (IV dosing)"
#>
#> $aumcivint.all$desc
#> [1] "The AUMCint,all calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#>
#> $aumcivint.all$sparse
#> [1] FALSE
#>
#> $aumcivint.all$formalsmap
#> $aumcivint.all$formalsmap$aumc
#> [1] "aumcint.all"
#>
#>
#> $aumcivint.all$depends
#> [1] "aumcint.all" "c0"
#>
#> $aumcivint.all$datatype
#> [1] "interval"
#>
#> $aumcivint.all$pptestcd_cdisc
#> [1] "aumcivint.all"
#>
#> $aumcivint.all$pptest_cdisc
#> [1] "The AUMCint,all calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#>
#>
#> $half.life
#> $half.life$FUN
#> [1] "pk.calc.half.life"
#>
#> $half.life$values
#> [1] FALSE TRUE
#>
#> $half.life$unit_type
#> [1] "time"
#>
#> $half.life$pretty_name
#> [1] "Half-life"
#>
#> $half.life$desc
#> [1] "The (terminal) half-life"
#>
#> $half.life$sparse
#> [1] FALSE
#>
#> $half.life$formalsmap
#> list()
#>
#> $half.life$depends
#> [1] "tmax" "tlast"
#>
#> $half.life$datatype
#> [1] "interval"
#>
#> $half.life$pptestcd_cdisc
#> [1] "LAMZHL"
#>
#> $half.life$pptest_cdisc
#> [1] "Half-Life Lambda z"
#>
#>
#> $r.squared
#> $r.squared$FUN
#> [1] NA
#>
#> $r.squared$values
#> [1] FALSE TRUE
#>
#> $r.squared$unit_type
#> [1] "unitless"
#>
#> $r.squared$pretty_name
#> [1] "$r^2$"
#>
#> $r.squared$desc
#> [1] "The r^2 value of the half-life calculation"
#>
#> $r.squared$sparse
#> [1] FALSE
#>
#> $r.squared$formalsmap
#> list()
#>
#> $r.squared$depends
#> [1] "half.life"
#>
#> $r.squared$datatype
#> [1] "interval"
#>
#> $r.squared$pptestcd_cdisc
#> [1] "R2"
#>
#> $r.squared$pptest_cdisc
#> [1] "R Squared"
#>
#>
#> $adj.r.squared
#> $adj.r.squared$FUN
#> [1] NA
#>
#> $adj.r.squared$values
#> [1] FALSE TRUE
#>
#> $adj.r.squared$unit_type
#> [1] "unitless"
#>
#> $adj.r.squared$pretty_name
#> [1] "$r^2_{adj}$"
#>
#> $adj.r.squared$desc
#> [1] "The adjusted r^2 value of the half-life calculation"
#>
#> $adj.r.squared$sparse
#> [1] FALSE
#>
#> $adj.r.squared$formalsmap
#> list()
#>
#> $adj.r.squared$depends
#> [1] "half.life"
#>
#> $adj.r.squared$datatype
#> [1] "interval"
#>
#> $adj.r.squared$pptestcd_cdisc
#> [1] "R2ADJ"
#>
#> $adj.r.squared$pptest_cdisc
#> [1] "R Squared Adjusted"
#>
#>
#> $lambda.z.corrxy
#> $lambda.z.corrxy$FUN
#> [1] NA
#>
#> $lambda.z.corrxy$values
#> [1] FALSE TRUE
#>
#> $lambda.z.corrxy$unit_type
#> [1] "unitless"
#>
#> $lambda.z.corrxy$pretty_name
#> [1] "Correlation (time, log-conc)"
#>
#> $lambda.z.corrxy$desc
#> [1] "Correlation between time and log-concentration for lambda.z points"
#>
#> $lambda.z.corrxy$sparse
#> [1] FALSE
#>
#> $lambda.z.corrxy$formalsmap
#> list()
#>
#> $lambda.z.corrxy$depends
#> [1] "half.life"
#>
#> $lambda.z.corrxy$datatype
#> [1] "interval"
#>
#> $lambda.z.corrxy$pptestcd_cdisc
#> [1] "CORRXY"
#>
#> $lambda.z.corrxy$pptest_cdisc
#> [1] "Correlation Between TimeX and Log ConcY"
#>
#>
#> $lambda.z
#> $lambda.z$FUN
#> [1] NA
#>
#> $lambda.z$values
#> [1] FALSE TRUE
#>
#> $lambda.z$unit_type
#> [1] "inverse_time"
#>
#> $lambda.z$pretty_name
#> [1] "$\\lambda_z$"
#>
#> $lambda.z$desc
#> [1] "The elimination rate of the terminal half-life"
#>
#> $lambda.z$sparse
#> [1] FALSE
#>
#> $lambda.z$formalsmap
#> list()
#>
#> $lambda.z$depends
#> [1] "half.life"
#>
#> $lambda.z$datatype
#> [1] "interval"
#>
#> $lambda.z$pptestcd_cdisc
#> [1] "LAMZ"
#>
#> $lambda.z$pptest_cdisc
#> [1] "Lambda z"
#>
#>
#> $lambda.z.time.first
#> $lambda.z.time.first$FUN
#> [1] NA
#>
#> $lambda.z.time.first$values
#> [1] FALSE TRUE
#>
#> $lambda.z.time.first$unit_type
#> [1] "time"
#>
#> $lambda.z.time.first$pretty_name
#> [1] "First time for $\\lambda_z$"
#>
#> $lambda.z.time.first$desc
#> [1] "The first time point used for the calculation of half-life"
#>
#> $lambda.z.time.first$sparse
#> [1] FALSE
#>
#> $lambda.z.time.first$formalsmap
#> list()
#>
#> $lambda.z.time.first$depends
#> [1] "half.life"
#>
#> $lambda.z.time.first$datatype
#> [1] "interval"
#>
#> $lambda.z.time.first$pptestcd_cdisc
#> [1] "LAMZLL"
#>
#> $lambda.z.time.first$pptest_cdisc
#> [1] "Lambda z Lower Limit"
#>
#>
#> $lambda.z.time.last
#> $lambda.z.time.last$FUN
#> [1] NA
#>
#> $lambda.z.time.last$values
#> [1] FALSE TRUE
#>
#> $lambda.z.time.last$unit_type
#> [1] "time"
#>
#> $lambda.z.time.last$pretty_name
#> [1] "Last time for $\\lambda_z$"
#>
#> $lambda.z.time.last$desc
#> [1] "The last time point used for the calculation of half-life"
#>
#> $lambda.z.time.last$sparse
#> [1] FALSE
#>
#> $lambda.z.time.last$formalsmap
#> list()
#>
#> $lambda.z.time.last$depends
#> [1] "half.life"
#>
#> $lambda.z.time.last$datatype
#> [1] "interval"
#>
#> $lambda.z.time.last$pptestcd_cdisc
#> [1] "LAMZUL"
#>
#> $lambda.z.time.last$pptest_cdisc
#> [1] "Lambda z Upper Limit"
#>
#>
#> $lambda.z.n.points
#> $lambda.z.n.points$FUN
#> [1] NA
#>
#> $lambda.z.n.points$values
#> [1] FALSE TRUE
#>
#> $lambda.z.n.points$unit_type
#> [1] "count"
#>
#> $lambda.z.n.points$pretty_name
#> [1] "Number of points used for lambda_z"
#>
#> $lambda.z.n.points$desc
#> [1] "The number of points used for the calculation of half-life"
#>
#> $lambda.z.n.points$sparse
#> [1] FALSE
#>
#> $lambda.z.n.points$formalsmap
#> list()
#>
#> $lambda.z.n.points$depends
#> [1] "half.life"
#>
#> $lambda.z.n.points$datatype
#> [1] "interval"
#>
#> $lambda.z.n.points$pptestcd_cdisc
#> [1] "LAMZNPT"
#>
#> $lambda.z.n.points$pptest_cdisc
#> [1] "Number of Points for Lambda z"
#>
#>
#> $clast.pred
#> $clast.pred$FUN
#> [1] NA
#>
#> $clast.pred$values
#> [1] FALSE TRUE
#>
#> $clast.pred$unit_type
#> [1] "conc"
#>
#> $clast.pred$pretty_name
#> [1] "Clast,pred"
#>
#> $clast.pred$desc
#> [1] "The concentration at Tlast as predicted by the half-life"
#>
#> $clast.pred$sparse
#> [1] FALSE
#>
#> $clast.pred$formalsmap
#> list()
#>
#> $clast.pred$depends
#> [1] "half.life"
#>
#> $clast.pred$datatype
#> [1] "interval"
#>
#> $clast.pred$pptestcd_cdisc
#> [1] "CLSTP"
#>
#> $clast.pred$pptest_cdisc
#> [1] "Clast pred"
#>
#>
#> $span.ratio
#> $span.ratio$FUN
#> [1] NA
#>
#> $span.ratio$values
#> [1] FALSE TRUE
#>
#> $span.ratio$unit_type
#> [1] "fraction"
#>
#> $span.ratio$pretty_name
#> [1] "Span ratio"
#>
#> $span.ratio$desc
#> [1] "The ratio of the half-life to the duration used for half-life calculation"
#>
#> $span.ratio$sparse
#> [1] FALSE
#>
#> $span.ratio$formalsmap
#> list()
#>
#> $span.ratio$depends
#> [1] "half.life"
#>
#> $span.ratio$datatype
#> [1] "interval"
#>
#> $span.ratio$pptestcd_cdisc
#> [1] "LAMZSPN"
#>
#> $span.ratio$pptest_cdisc
#> [1] "Lambda z Span"
#>
#>
#> $tobit_residual
#> $tobit_residual$FUN
#> [1] NA
#>
#> $tobit_residual$values
#> [1] FALSE TRUE
#>
#> $tobit_residual$unit_type
#> [1] "unitless"
#>
#> $tobit_residual$pretty_name
#> [1] "Tobit residual SD"
#>
#> $tobit_residual$desc
#> [1] "The estimated residual standard deviation (on the log-concentration scale) from the Tobit half-life fit"
#>
#> $tobit_residual$sparse
#> [1] FALSE
#>
#> $tobit_residual$formalsmap
#> list()
#>
#> $tobit_residual$depends
#> [1] "half.life"
#>
#> $tobit_residual$datatype
#> [1] "interval"
#>
#> $tobit_residual$pptestcd_cdisc
#> [1] "tobit_residual"
#>
#> $tobit_residual$pptest_cdisc
#> [1] "The estimated residual standard deviation (on the log-concentration scale) from the Tobit half-life fit"
#>
#>
#> $adj_tobit_residual
#> $adj_tobit_residual$FUN
#> [1] NA
#>
#> $adj_tobit_residual$values
#> [1] FALSE TRUE
#>
#> $adj_tobit_residual$unit_type
#> [1] "unitless"
#>
#> $adj_tobit_residual$pretty_name
#> [1] "Adjusted Tobit residual SD"
#>
#> $adj_tobit_residual$desc
#> [1] "The adjusted Tobit residual standard deviation (analogous to adjusted r-squared; penalizes smaller windows)"
#>
#> $adj_tobit_residual$sparse
#> [1] FALSE
#>
#> $adj_tobit_residual$formalsmap
#> list()
#>
#> $adj_tobit_residual$depends
#> [1] "half.life"
#>
#> $adj_tobit_residual$datatype
#> [1] "interval"
#>
#> $adj_tobit_residual$pptestcd_cdisc
#> [1] "adj_tobit_residual"
#>
#> $adj_tobit_residual$pptest_cdisc
#> [1] "The adjusted Tobit residual standard deviation (analogous to adjusted r-squared; penalizes smaller windows)"
#>
#>
#> $lambda.z.n.points_blq
#> $lambda.z.n.points_blq$FUN
#> [1] NA
#>
#> $lambda.z.n.points_blq$values
#> [1] FALSE TRUE
#>
#> $lambda.z.n.points_blq$unit_type
#> [1] "count"
#>
#> $lambda.z.n.points_blq$pretty_name
#> [1] "Number of BLQ points for lambda_z (Tobit)"
#>
#> $lambda.z.n.points_blq$desc
#> [1] "The number of BLQ points included in the Tobit half-life calculation"
#>
#> $lambda.z.n.points_blq$sparse
#> [1] FALSE
#>
#> $lambda.z.n.points_blq$formalsmap
#> list()
#>
#> $lambda.z.n.points_blq$depends
#> [1] "half.life"
#>
#> $lambda.z.n.points_blq$datatype
#> [1] "interval"
#>
#> $lambda.z.n.points_blq$pptestcd_cdisc
#> [1] "lambda.z.n.points_blq"
#>
#> $lambda.z.n.points_blq$pptest_cdisc
#> [1] "The number of BLQ points included in the Tobit half-life calculation"
#>
#>
#> $thalf.eff.last
#> $thalf.eff.last$FUN
#> [1] "pk.calc.thalf.eff"
#>
#> $thalf.eff.last$values
#> [1] FALSE TRUE
#>
#> $thalf.eff.last$unit_type
#> [1] "time"
#>
#> $thalf.eff.last$pretty_name
#> [1] "Effective half-life (based on MRT,last)"
#>
#> $thalf.eff.last$desc
#> [1] "The effective half-life (as determined from the MRTlast)"
#>
#> $thalf.eff.last$sparse
#> [1] FALSE
#>
#> $thalf.eff.last$formalsmap
#> $thalf.eff.last$formalsmap$mrt
#> [1] "mrt.last"
#>
#>
#> $thalf.eff.last$depends
#> [1] "mrt.last"
#>
#> $thalf.eff.last$datatype
#> [1] "interval"
#>
#> $thalf.eff.last$pptestcd_cdisc
#> [1] "EFFHL"
#>
#> $thalf.eff.last$pptest_cdisc
#> [1] "Effective Half-Life (based on AUClast)"
#>
#>
#> $thalf.eff.iv.last
#> $thalf.eff.iv.last$FUN
#> [1] "pk.calc.thalf.eff"
#>
#> $thalf.eff.iv.last$values
#> [1] FALSE TRUE
#>
#> $thalf.eff.iv.last$unit_type
#> [1] "time"
#>
#> $thalf.eff.iv.last$pretty_name
#> [1] "Effective half-life (for IV dosing, based on MRTlast)"
#>
#> $thalf.eff.iv.last$desc
#> [1] "The effective half-life (as determined from the intravenous MRTlast)"
#>
#> $thalf.eff.iv.last$sparse
#> [1] FALSE
#>
#> $thalf.eff.iv.last$formalsmap
#> $thalf.eff.iv.last$formalsmap$mrt
#> [1] "mrt.iv.last"
#>
#>
#> $thalf.eff.iv.last$depends
#> [1] "mrt.iv.last"
#>
#> $thalf.eff.iv.last$datatype
#> [1] "interval"
#>
#> $thalf.eff.iv.last$pptestcd_cdisc
#> [1] "EFFIVLHL"
#>
#> $thalf.eff.iv.last$pptest_cdisc
#> [1] "Effective Half-Life (for IV dosing, based on AUClast)"
#>
#>
#> $kel.last
#> $kel.last$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.last$values
#> [1] FALSE TRUE
#>
#> $kel.last$unit_type
#> [1] "inverse_time"
#>
#> $kel.last$pretty_name
#> [1] "Kel (based on AUClast)"
#>
#> $kel.last$desc
#> [1] "Elimination rate (as calculated from the MRT using AUClast)"
#>
#> $kel.last$sparse
#> [1] FALSE
#>
#> $kel.last$formalsmap
#> $kel.last$formalsmap$mrt
#> [1] "mrt.last"
#>
#>
#> $kel.last$depends
#> [1] "mrt.last"
#>
#> $kel.last$datatype
#> [1] "interval"
#>
#> $kel.last$pptestcd_cdisc
#> [1] "KELLST"
#>
#> $kel.last$pptest_cdisc
#> [1] "Kel (based on AUClast)"
#>
#>
#> $kel.iv.last
#> $kel.iv.last$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.iv.last$values
#> [1] FALSE TRUE
#>
#> $kel.iv.last$unit_type
#> [1] "inverse_time"
#>
#> $kel.iv.last$pretty_name
#> [1] "Kel (for IV dosing, based on AUClast)"
#>
#> $kel.iv.last$desc
#> [1] "Elimination rate (as calculated from the intravenous MRTlast)"
#>
#> $kel.iv.last$sparse
#> [1] FALSE
#>
#> $kel.iv.last$formalsmap
#> $kel.iv.last$formalsmap$mrt
#> [1] "mrt.iv.last"
#>
#>
#> $kel.iv.last$depends
#> [1] "mrt.iv.last"
#>
#> $kel.iv.last$datatype
#> [1] "interval"
#>
#> $kel.iv.last$pptestcd_cdisc
#> [1] "KELIVLT"
#>
#> $kel.iv.last$pptest_cdisc
#> [1] "Kel (for IV dosing, based on AUClast)"
#>
#>
#> $kel.all
#> $kel.all$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.all$values
#> [1] FALSE TRUE
#>
#> $kel.all$unit_type
#> [1] "inverse_time"
#>
#> $kel.all$pretty_name
#> [1] "Kel (based on AUCall)"
#>
#> $kel.all$desc
#> [1] "Elimination rate (as calculated from the MRTall)"
#>
#> $kel.all$sparse
#> [1] FALSE
#>
#> $kel.all$formalsmap
#> $kel.all$formalsmap$mrt
#> [1] "mrt.all"
#>
#>
#> $kel.all$depends
#> [1] "mrt.all"
#>
#> $kel.all$datatype
#> [1] "interval"
#>
#> $kel.all$pptestcd_cdisc
#> [1] "kel.all"
#>
#> $kel.all$pptest_cdisc
#> [1] "Elimination rate (as calculated from the MRTall)"
#>
#>
#> $kel.int.all
#> $kel.int.all$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.int.all$values
#> [1] FALSE TRUE
#>
#> $kel.int.all$unit_type
#> [1] "inverse_time"
#>
#> $kel.int.all$pretty_name
#> [1] "Kel (based on AUCint.all)"
#>
#> $kel.int.all$desc
#> [1] "Elimination rate (as calculated from the MRTint.all)"
#>
#> $kel.int.all$sparse
#> [1] FALSE
#>
#> $kel.int.all$formalsmap
#> $kel.int.all$formalsmap$mrt
#> [1] "mrt.int.all"
#>
#>
#> $kel.int.all$depends
#> [1] "mrt.int.all"
#>
#> $kel.int.all$datatype
#> [1] "interval"
#>
#> $kel.int.all$pptestcd_cdisc
#> [1] "kel.int.all"
#>
#> $kel.int.all$pptest_cdisc
#> [1] "Elimination rate (as calculated from the MRTint.all)"
#>
#>
#> $kel.int.last
#> $kel.int.last$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.int.last$values
#> [1] FALSE TRUE
#>
#> $kel.int.last$unit_type
#> [1] "inverse_time"
#>
#> $kel.int.last$pretty_name
#> [1] "Kel (based on AUCint.last)"
#>
#> $kel.int.last$desc
#> [1] "Elimination rate (as calculated from the MRTint.last)"
#>
#> $kel.int.last$sparse
#> [1] FALSE
#>
#> $kel.int.last$formalsmap
#> $kel.int.last$formalsmap$mrt
#> [1] "mrt.int.last"
#>
#>
#> $kel.int.last$depends
#> [1] "mrt.int.last"
#>
#> $kel.int.last$datatype
#> [1] "interval"
#>
#> $kel.int.last$pptestcd_cdisc
#> [1] "kel.int.last"
#>
#> $kel.int.last$pptest_cdisc
#> [1] "Elimination rate (as calculated from the MRTint.last)"
#>
#>
#> $cl.iv.all
#> $cl.iv.all$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.iv.all$values
#> [1] FALSE TRUE
#>
#> $cl.iv.all$unit_type
#> [1] "clearance"
#>
#> $cl.iv.all$pretty_name
#> [1] "CL (for IV dosing, based on AUCall)"
#>
#> $cl.iv.all$desc
#> [1] "Clearance for intravenous dosing calculated with AUCall"
#>
#> $cl.iv.all$sparse
#> [1] FALSE
#>
#> $cl.iv.all$formalsmap
#> $cl.iv.all$formalsmap$auc
#> [1] "aucivall"
#>
#>
#> $cl.iv.all$depends
#> [1] "aucivall"
#>
#> $cl.iv.all$datatype
#> [1] "interval"
#>
#> $cl.iv.all$pptestcd_cdisc
#> [1] "cl.iv.all"
#>
#> $cl.iv.all$pptest_cdisc
#> [1] "Clearance for intravenous dosing calculated with AUCall"
#>
#>
#> $cl.iv.last
#> $cl.iv.last$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.iv.last$values
#> [1] FALSE TRUE
#>
#> $cl.iv.last$unit_type
#> [1] "clearance"
#>
#> $cl.iv.last$pretty_name
#> [1] "CL (for IV dosing, based on AUClast)"
#>
#> $cl.iv.last$desc
#> [1] "Clearance for intravenous dosing calculated with AUClast"
#>
#> $cl.iv.last$sparse
#> [1] FALSE
#>
#> $cl.iv.last$formalsmap
#> $cl.iv.last$formalsmap$auc
#> [1] "aucivlast"
#>
#>
#> $cl.iv.last$depends
#> [1] "aucivlast"
#>
#> $cl.iv.last$datatype
#> [1] "interval"
#>
#> $cl.iv.last$pptestcd_cdisc
#> [1] "cl.iv.last"
#>
#> $cl.iv.last$pptest_cdisc
#> [1] "Clearance for intravenous dosing calculated with AUClast"
#>
#>
#> $cl.ivint.all
#> $cl.ivint.all$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.ivint.all$values
#> [1] FALSE TRUE
#>
#> $cl.ivint.all$unit_type
#> [1] "clearance"
#>
#> $cl.ivint.all$pretty_name
#> [1] "CL (IV dose interval, based on AUCint.all)"
#>
#> $cl.ivint.all$desc
#> [1] "Clearance for intravenous dosing calculated with interval AUCint.all"
#>
#> $cl.ivint.all$sparse
#> [1] FALSE
#>
#> $cl.ivint.all$formalsmap
#> $cl.ivint.all$formalsmap$auc
#> [1] "aucivint.all"
#>
#>
#> $cl.ivint.all$depends
#> [1] "aucivint.all"
#>
#> $cl.ivint.all$datatype
#> [1] "interval"
#>
#> $cl.ivint.all$pptestcd_cdisc
#> [1] "cl.ivint.all"
#>
#> $cl.ivint.all$pptest_cdisc
#> [1] "Clearance for intravenous dosing calculated with interval AUCint.all"
#>
#>
#> $cl.ivint.last
#> $cl.ivint.last$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.ivint.last$values
#> [1] FALSE TRUE
#>
#> $cl.ivint.last$unit_type
#> [1] "clearance"
#>
#> $cl.ivint.last$pretty_name
#> [1] "CL (IV dose interval, based on AUCint.last)"
#>
#> $cl.ivint.last$desc
#> [1] "Clearance for intravenous dosing calculated with interval AUCint.last"
#>
#> $cl.ivint.last$sparse
#> [1] FALSE
#>
#> $cl.ivint.last$formalsmap
#> $cl.ivint.last$formalsmap$auc
#> [1] "aucivint.last"
#>
#>
#> $cl.ivint.last$depends
#> [1] "aucivint.last"
#>
#> $cl.ivint.last$datatype
#> [1] "interval"
#>
#> $cl.ivint.last$pptestcd_cdisc
#> [1] "cl.ivint.last"
#>
#> $cl.ivint.last$pptest_cdisc
#> [1] "Clearance for intravenous dosing calculated with interval AUCint.last"
#>
#>
#> $cl.sparse.last
#> $cl.sparse.last$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.sparse.last$values
#> [1] FALSE TRUE
#>
#> $cl.sparse.last$unit_type
#> [1] "clearance"
#>
#> $cl.sparse.last$pretty_name
#> [1] "CL (for sparse data, based on AUClast)"
#>
#> $cl.sparse.last$desc
#> [1] "Clearance from sparse sampling calculated with population AUClast"
#>
#> $cl.sparse.last$sparse
#> [1] TRUE
#>
#> $cl.sparse.last$formalsmap
#> $cl.sparse.last$formalsmap$auc
#> [1] "sparse_auclast"
#>
#>
#> $cl.sparse.last$depends
#> [1] "sparse_auclast"
#>
#> $cl.sparse.last$datatype
#> [1] "interval"
#>
#> $cl.sparse.last$pptestcd_cdisc
#> [1] "cl.sparse.last"
#>
#> $cl.sparse.last$pptest_cdisc
#> [1] "Clearance from sparse sampling calculated with population AUClast"
#>
#>
#> $mrt.sparse.last
#> $mrt.sparse.last$FUN
#> [1] "pk.calc.mrt"
#>
#> $mrt.sparse.last$values
#> [1] FALSE TRUE
#>
#> $mrt.sparse.last$unit_type
#> [1] "time"
#>
#> $mrt.sparse.last$pretty_name
#> [1] "MRT (for sparse data, based on AUClast)"
#>
#> $mrt.sparse.last$desc
#> [1] "Mean residence time from sparse sampling"
#>
#> $mrt.sparse.last$sparse
#> [1] TRUE
#>
#> $mrt.sparse.last$formalsmap
#> $mrt.sparse.last$formalsmap$auc
#> [1] "sparse_auclast"
#>
#> $mrt.sparse.last$formalsmap$aumc
#> [1] "sparse_aumclast"
#>
#>
#> $mrt.sparse.last$depends
#> [1] "sparse_auclast" "sparse_aumclast"
#>
#> $mrt.sparse.last$datatype
#> [1] "interval"
#>
#> $mrt.sparse.last$pptestcd_cdisc
#> [1] "mrt.sparse.last"
#>
#> $mrt.sparse.last$pptest_cdisc
#> [1] "Mean residence time from sparse sampling"
#>
#>
#> $mrt.iv.all
#> $mrt.iv.all$FUN
#> [1] "pk.calc.mrt.iv"
#>
#> $mrt.iv.all$values
#> [1] FALSE TRUE
#>
#> $mrt.iv.all$unit_type
#> [1] "time"
#>
#> $mrt.iv.all$pretty_name
#> [1] "MRT (for IV dosing, based on AUCall)"
#>
#> $mrt.iv.all$desc
#> [1] "Mean residence time for IV dosing calculated with AUCall/AUMCall"
#>
#> $mrt.iv.all$sparse
#> [1] FALSE
#>
#> $mrt.iv.all$formalsmap
#> $mrt.iv.all$formalsmap$auc
#> [1] "aucivall"
#>
#> $mrt.iv.all$formalsmap$aumc
#> [1] "aumcivall"
#>
#>
#> $mrt.iv.all$depends
#> [1] "aucivall" "aumcivall"
#>
#> $mrt.iv.all$datatype
#> [1] "interval"
#>
#> $mrt.iv.all$pptestcd_cdisc
#> [1] "mrt.iv.all"
#>
#> $mrt.iv.all$pptest_cdisc
#> [1] "Mean residence time for IV dosing calculated with AUCall/AUMCall"
#>
#>
#> $mrt.ivint.all
#> $mrt.ivint.all$FUN
#> [1] "pk.calc.mrt.iv"
#>
#> $mrt.ivint.all$values
#> [1] FALSE TRUE
#>
#> $mrt.ivint.all$unit_type
#> [1] "time"
#>
#> $mrt.ivint.all$pretty_name
#> [1] "MRT (IV dose interval, based on AUCint.all)"
#>
#> $mrt.ivint.all$desc
#> [1] "Mean residence time for IV interval calculated with AUCint.all/AUMCint.all"
#>
#> $mrt.ivint.all$sparse
#> [1] FALSE
#>
#> $mrt.ivint.all$formalsmap
#> $mrt.ivint.all$formalsmap$auc
#> [1] "aucivint.all"
#>
#> $mrt.ivint.all$formalsmap$aumc
#> [1] "aumcivint.all"
#>
#>
#> $mrt.ivint.all$depends
#> [1] "aucivint.all" "aumcivint.all"
#>
#> $mrt.ivint.all$datatype
#> [1] "interval"
#>
#> $mrt.ivint.all$pptestcd_cdisc
#> [1] "mrt.ivint.all"
#>
#> $mrt.ivint.all$pptest_cdisc
#> [1] "Mean residence time for IV interval calculated with AUCint.all/AUMCint.all"
#>
#>
#> $mrt.ivint.last
#> $mrt.ivint.last$FUN
#> [1] "pk.calc.mrt.iv"
#>
#> $mrt.ivint.last$values
#> [1] FALSE TRUE
#>
#> $mrt.ivint.last$unit_type
#> [1] "time"
#>
#> $mrt.ivint.last$pretty_name
#> [1] "MRT (IV dose interval, based on AUCint.last)"
#>
#> $mrt.ivint.last$desc
#> [1] "Mean residence time for IV interval calculated with AUCint.last/AUMCint.last"
#>
#> $mrt.ivint.last$sparse
#> [1] FALSE
#>
#> $mrt.ivint.last$formalsmap
#> $mrt.ivint.last$formalsmap$auc
#> [1] "aucivint.last"
#>
#> $mrt.ivint.last$formalsmap$aumc
#> [1] "aumcivint.last"
#>
#>
#> $mrt.ivint.last$depends
#> [1] "aucivint.last" "aumcivint.last"
#>
#> $mrt.ivint.last$datatype
#> [1] "interval"
#>
#> $mrt.ivint.last$pptestcd_cdisc
#> [1] "mrt.ivint.last"
#>
#> $mrt.ivint.last$pptest_cdisc
#> [1] "Mean residence time for IV interval calculated with AUCint.last/AUMCint.last"
#>
#>
#> $vz.all
#> $vz.all$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.all$values
#> [1] FALSE TRUE
#>
#> $vz.all$unit_type
#> [1] "volume"
#>
#> $vz.all$pretty_name
#> [1] "Vz (based on AUCall)"
#>
#> $vz.all$desc
#> [1] "Terminal volume of distribution calculated with AUCall-based CL"
#>
#> $vz.all$sparse
#> [1] FALSE
#>
#> $vz.all$formalsmap
#> $vz.all$formalsmap$cl
#> [1] "cl.all"
#>
#>
#> $vz.all$depends
#> [1] "cl.all" "lambda.z"
#>
#> $vz.all$datatype
#> [1] "interval"
#>
#> $vz.all$pptestcd_cdisc
#> [1] "vz.all"
#>
#> $vz.all$pptest_cdisc
#> [1] "Terminal volume of distribution calculated with AUCall-based CL"
#>
#>
#> $vz.int.all
#> $vz.int.all$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.int.all$values
#> [1] FALSE TRUE
#>
#> $vz.int.all$unit_type
#> [1] "volume"
#>
#> $vz.int.all$pretty_name
#> [1] "Vz (based on AUCint.all)"
#>
#> $vz.int.all$desc
#> [1] "Terminal volume of distribution using interval AUCint.all"
#>
#> $vz.int.all$sparse
#> [1] FALSE
#>
#> $vz.int.all$formalsmap
#> $vz.int.all$formalsmap$cl
#> [1] "cl.int.all"
#>
#>
#> $vz.int.all$depends
#> [1] "cl.int.all" "lambda.z"
#>
#> $vz.int.all$datatype
#> [1] "interval"
#>
#> $vz.int.all$pptestcd_cdisc
#> [1] "vz.int.all"
#>
#> $vz.int.all$pptest_cdisc
#> [1] "Terminal volume of distribution using interval AUCint.all"
#>
#>
#> $vz.int.last
#> $vz.int.last$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.int.last$values
#> [1] FALSE TRUE
#>
#> $vz.int.last$unit_type
#> [1] "volume"
#>
#> $vz.int.last$pretty_name
#> [1] "Vz (based on AUCint.last)"
#>
#> $vz.int.last$desc
#> [1] "Terminal volume of distribution using interval AUCint.last"
#>
#> $vz.int.last$sparse
#> [1] FALSE
#>
#> $vz.int.last$formalsmap
#> $vz.int.last$formalsmap$cl
#> [1] "cl.int.last"
#>
#>
#> $vz.int.last$depends
#> [1] "cl.int.last" "lambda.z"
#>
#> $vz.int.last$datatype
#> [1] "interval"
#>
#> $vz.int.last$pptestcd_cdisc
#> [1] "vz.int.last"
#>
#> $vz.int.last$pptest_cdisc
#> [1] "Terminal volume of distribution using interval AUCint.last"
#>
#>
#> $vz.iv.all
#> $vz.iv.all$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.iv.all$values
#> [1] FALSE TRUE
#>
#> $vz.iv.all$unit_type
#> [1] "volume"
#>
#> $vz.iv.all$pretty_name
#> [1] "Vz (for IV dosing, based on AUCall)"
#>
#> $vz.iv.all$desc
#> [1] "Terminal volume of distribution for IV dosing using AUCall"
#>
#> $vz.iv.all$sparse
#> [1] FALSE
#>
#> $vz.iv.all$formalsmap
#> $vz.iv.all$formalsmap$cl
#> [1] "cl.iv.all"
#>
#>
#> $vz.iv.all$depends
#> [1] "cl.iv.all" "lambda.z"
#>
#> $vz.iv.all$datatype
#> [1] "interval"
#>
#> $vz.iv.all$pptestcd_cdisc
#> [1] "vz.iv.all"
#>
#> $vz.iv.all$pptest_cdisc
#> [1] "Terminal volume of distribution for IV dosing using AUCall"
#>
#>
#> $vz.iv.last
#> $vz.iv.last$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.iv.last$values
#> [1] FALSE TRUE
#>
#> $vz.iv.last$unit_type
#> [1] "volume"
#>
#> $vz.iv.last$pretty_name
#> [1] "Vz (for IV dosing, based on AUClast)"
#>
#> $vz.iv.last$desc
#> [1] "Terminal volume of distribution for IV dosing using AUClast"
#>
#> $vz.iv.last$sparse
#> [1] FALSE
#>
#> $vz.iv.last$formalsmap
#> $vz.iv.last$formalsmap$cl
#> [1] "cl.iv.last"
#>
#>
#> $vz.iv.last$depends
#> [1] "cl.iv.last" "lambda.z"
#>
#> $vz.iv.last$datatype
#> [1] "interval"
#>
#> $vz.iv.last$pptestcd_cdisc
#> [1] "vz.iv.last"
#>
#> $vz.iv.last$pptest_cdisc
#> [1] "Terminal volume of distribution for IV dosing using AUClast"
#>
#>
#> $vz.ivint.all
#> $vz.ivint.all$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.ivint.all$values
#> [1] FALSE TRUE
#>
#> $vz.ivint.all$unit_type
#> [1] "volume"
#>
#> $vz.ivint.all$pretty_name
#> [1] "Vz (IV dose interval, based on AUCint.all)"
#>
#> $vz.ivint.all$desc
#> [1] "Terminal volume of distribution for IV interval using AUCint.all"
#>
#> $vz.ivint.all$sparse
#> [1] FALSE
#>
#> $vz.ivint.all$formalsmap
#> $vz.ivint.all$formalsmap$cl
#> [1] "cl.ivint.all"
#>
#>
#> $vz.ivint.all$depends
#> [1] "cl.ivint.all" "lambda.z"
#>
#> $vz.ivint.all$datatype
#> [1] "interval"
#>
#> $vz.ivint.all$pptestcd_cdisc
#> [1] "vz.ivint.all"
#>
#> $vz.ivint.all$pptest_cdisc
#> [1] "Terminal volume of distribution for IV interval using AUCint.all"
#>
#>
#> $vz.ivint.last
#> $vz.ivint.last$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.ivint.last$values
#> [1] FALSE TRUE
#>
#> $vz.ivint.last$unit_type
#> [1] "volume"
#>
#> $vz.ivint.last$pretty_name
#> [1] "Vz (IV dose interval, based on AUCint.last)"
#>
#> $vz.ivint.last$desc
#> [1] "Terminal volume of distribution for IV interval using AUCint.last"
#>
#> $vz.ivint.last$sparse
#> [1] FALSE
#>
#> $vz.ivint.last$formalsmap
#> $vz.ivint.last$formalsmap$cl
#> [1] "cl.ivint.last"
#>
#>
#> $vz.ivint.last$depends
#> [1] "cl.ivint.last" "lambda.z"
#>
#> $vz.ivint.last$datatype
#> [1] "interval"
#>
#> $vz.ivint.last$pptestcd_cdisc
#> [1] "vz.ivint.last"
#>
#> $vz.ivint.last$pptest_cdisc
#> [1] "Terminal volume of distribution for IV interval using AUCint.last"
#>
#>
#> $vz.last
#> $vz.last$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.last$values
#> [1] FALSE TRUE
#>
#> $vz.last$unit_type
#> [1] "volume"
#>
#> $vz.last$pretty_name
#> [1] "Vz (based on AUClast)"
#>
#> $vz.last$desc
#> [1] "Terminal volume of distribution calculated with AUClast-based CL"
#>
#> $vz.last$sparse
#> [1] FALSE
#>
#> $vz.last$formalsmap
#> $vz.last$formalsmap$cl
#> [1] "cl.last"
#>
#>
#> $vz.last$depends
#> [1] "cl.last" "lambda.z"
#>
#> $vz.last$datatype
#> [1] "interval"
#>
#> $vz.last$pptestcd_cdisc
#> [1] "vz.last"
#>
#> $vz.last$pptest_cdisc
#> [1] "Terminal volume of distribution calculated with AUClast-based CL"
#>
#>
#> $vss.iv.all
#> $vss.iv.all$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.iv.all$values
#> [1] FALSE TRUE
#>
#> $vss.iv.all$unit_type
#> [1] "volume"
#>
#> $vss.iv.all$pretty_name
#> [1] "Vss (for IV dosing, based on AUCall)"
#>
#> $vss.iv.all$desc
#> [1] "Steady-state volume of distribution for IV dosing using AUCall"
#>
#> $vss.iv.all$sparse
#> [1] FALSE
#>
#> $vss.iv.all$formalsmap
#> $vss.iv.all$formalsmap$cl
#> [1] "cl.iv.all"
#>
#> $vss.iv.all$formalsmap$mrt
#> [1] "mrt.iv.all"
#>
#>
#> $vss.iv.all$depends
#> [1] "cl.iv.all" "mrt.iv.all"
#>
#> $vss.iv.all$datatype
#> [1] "interval"
#>
#> $vss.iv.all$pptestcd_cdisc
#> [1] "vss.iv.all"
#>
#> $vss.iv.all$pptest_cdisc
#> [1] "Steady-state volume of distribution for IV dosing using AUCall"
#>
#>
#> $vss.ivint.all
#> $vss.ivint.all$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.ivint.all$values
#> [1] FALSE TRUE
#>
#> $vss.ivint.all$unit_type
#> [1] "volume"
#>
#> $vss.ivint.all$pretty_name
#> [1] "Vss (IV dose interval, based on AUCint.all)"
#>
#> $vss.ivint.all$desc
#> [1] "Steady-state volume of distribution for IV interval using AUCint.all"
#>
#> $vss.ivint.all$sparse
#> [1] FALSE
#>
#> $vss.ivint.all$formalsmap
#> $vss.ivint.all$formalsmap$cl
#> [1] "cl.ivint.all"
#>
#> $vss.ivint.all$formalsmap$mrt
#> [1] "mrt.ivint.all"
#>
#>
#> $vss.ivint.all$depends
#> [1] "cl.ivint.all" "mrt.ivint.all"
#>
#> $vss.ivint.all$datatype
#> [1] "interval"
#>
#> $vss.ivint.all$pptestcd_cdisc
#> [1] "vss.ivint.all"
#>
#> $vss.ivint.all$pptest_cdisc
#> [1] "Steady-state volume of distribution for IV interval using AUCint.all"
#>
#>
#> $vss.ivint.last
#> $vss.ivint.last$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.ivint.last$values
#> [1] FALSE TRUE
#>
#> $vss.ivint.last$unit_type
#> [1] "volume"
#>
#> $vss.ivint.last$pretty_name
#> [1] "Vss (IV dose interval, based on AUCint.last)"
#>
#> $vss.ivint.last$desc
#> [1] "Steady-state volume of distribution for IV interval using AUCint.last"
#>
#> $vss.ivint.last$sparse
#> [1] FALSE
#>
#> $vss.ivint.last$formalsmap
#> $vss.ivint.last$formalsmap$cl
#> [1] "cl.ivint.last"
#>
#> $vss.ivint.last$formalsmap$mrt
#> [1] "mrt.ivint.last"
#>
#>
#> $vss.ivint.last$depends
#> [1] "cl.ivint.last" "mrt.ivint.last"
#>
#> $vss.ivint.last$datatype
#> [1] "interval"
#>
#> $vss.ivint.last$pptestcd_cdisc
#> [1] "vss.ivint.last"
#>
#> $vss.ivint.last$pptest_cdisc
#> [1] "Steady-state volume of distribution for IV interval using AUCint.last"
#>
#>
#> $vss.sparse.last
#> $vss.sparse.last$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.sparse.last$values
#> [1] FALSE TRUE
#>
#> $vss.sparse.last$unit_type
#> [1] "volume"
#>
#> $vss.sparse.last$pretty_name
#> [1] "Vss (for sparse data, based on AUClast)"
#>
#> $vss.sparse.last$desc
#> [1] "Steady-state volume of distribution from sparse sampling"
#>
#> $vss.sparse.last$sparse
#> [1] TRUE
#>
#> $vss.sparse.last$formalsmap
#> $vss.sparse.last$formalsmap$cl
#> [1] "cl.sparse.last"
#>
#> $vss.sparse.last$formalsmap$mrt
#> [1] "mrt.sparse.last"
#>
#>
#> $vss.sparse.last$depends
#> [1] "cl.sparse.last" "mrt.sparse.last"
#>
#> $vss.sparse.last$datatype
#> [1] "interval"
#>
#> $vss.sparse.last$pptestcd_cdisc
#> [1] "vss.sparse.last"
#>
#> $vss.sparse.last$pptest_cdisc
#> [1] "Steady-state volume of distribution from sparse sampling"
#>
#>
#> $aucinf.obs
#> $aucinf.obs$FUN
#> [1] "pk.calc.auc.inf.obs"
#>
#> $aucinf.obs$values
#> [1] FALSE TRUE
#>
#> $aucinf.obs$unit_type
#> [1] "auc"
#>
#> $aucinf.obs$pretty_name
#> [1] "AUCinf,obs"
#>
#> $aucinf.obs$desc
#> [1] "The area under the concentration time curve from the beginning of the interval to infinity with extrapolation to infinity from the observed Clast"
#>
#> $aucinf.obs$sparse
#> [1] FALSE
#>
#> $aucinf.obs$formalsmap
#> list()
#>
#> $aucinf.obs$depends
#> [1] "lambda.z" "clast.obs"
#>
#> $aucinf.obs$datatype
#> [1] "interval"
#>
#> $aucinf.obs$pptestcd_cdisc
#> [1] "AUCIFO"
#>
#> $aucinf.obs$pptest_cdisc
#> [1] "AUC Infinity Obs"
#>
#>
#> $aucinf.pred
#> $aucinf.pred$FUN
#> [1] "pk.calc.auc.inf.pred"
#>
#> $aucinf.pred$values
#> [1] FALSE TRUE
#>
#> $aucinf.pred$unit_type
#> [1] "auc"
#>
#> $aucinf.pred$pretty_name
#> [1] "AUCinf,pred"
#>
#> $aucinf.pred$desc
#> [1] "The area under the concentration time curve from the beginning of the interval to infinity with extrapolation to infinity from the predicted Clast"
#>
#> $aucinf.pred$sparse
#> [1] FALSE
#>
#> $aucinf.pred$formalsmap
#> list()
#>
#> $aucinf.pred$depends
#> [1] "lambda.z" "clast.pred"
#>
#> $aucinf.pred$datatype
#> [1] "interval"
#>
#> $aucinf.pred$pptestcd_cdisc
#> [1] "AUCIFP"
#>
#> $aucinf.pred$pptest_cdisc
#> [1] "AUC Infinity Pred"
#>
#>
#> $aumcinf.obs
#> $aumcinf.obs$FUN
#> [1] "pk.calc.aumc.inf.obs"
#>
#> $aumcinf.obs$values
#> [1] FALSE TRUE
#>
#> $aumcinf.obs$unit_type
#> [1] "aumc"
#>
#> $aumcinf.obs$pretty_name
#> [1] "AUMC,inf,obs"
#>
#> $aumcinf.obs$desc
#> [1] "The area under the concentration time moment curve from the beginning of the interval to infinity with extrapolation to infinity from the observed Clast"
#>
#> $aumcinf.obs$sparse
#> [1] FALSE
#>
#> $aumcinf.obs$formalsmap
#> list()
#>
#> $aumcinf.obs$depends
#> [1] "lambda.z" "clast.obs"
#>
#> $aumcinf.obs$datatype
#> [1] "interval"
#>
#> $aumcinf.obs$pptestcd_cdisc
#> [1] "AUMCIFO"
#>
#> $aumcinf.obs$pptest_cdisc
#> [1] "AUMC Infinity Obs"
#>
#>
#> $aumcinf.pred
#> $aumcinf.pred$FUN
#> [1] "pk.calc.aumc.inf.pred"
#>
#> $aumcinf.pred$values
#> [1] FALSE TRUE
#>
#> $aumcinf.pred$unit_type
#> [1] "aumc"
#>
#> $aumcinf.pred$pretty_name
#> [1] "AUMC,inf,pred"
#>
#> $aumcinf.pred$desc
#> [1] "The area under the concentration time moment curve from the beginning of the interval to infinity with extrapolation to infinity from the predicted Clast"
#>
#> $aumcinf.pred$sparse
#> [1] FALSE
#>
#> $aumcinf.pred$formalsmap
#> list()
#>
#> $aumcinf.pred$depends
#> [1] "lambda.z" "clast.pred"
#>
#> $aumcinf.pred$datatype
#> [1] "interval"
#>
#> $aumcinf.pred$pptestcd_cdisc
#> [1] "AUMCIFP"
#>
#> $aumcinf.pred$pptest_cdisc
#> [1] "AUMC Infinity Pred"
#>
#>
#> $aucint.inf.obs
#> $aucint.inf.obs$FUN
#> [1] "pk.calc.aucint.inf.obs"
#>
#> $aucint.inf.obs$values
#> [1] FALSE TRUE
#>
#> $aucint.inf.obs$unit_type
#> [1] "auc"
#>
#> $aucint.inf.obs$pretty_name
#> [1] "AUCint (based on AUCinf,obs extrapolation)"
#>
#> $aucint.inf.obs$desc
#> [1] "The area under the concentration time curve in the interval extrapolating from Tlast to infinity with zeros (matching AUClast)"
#>
#> $aucint.inf.obs$sparse
#> [1] FALSE
#>
#> $aucint.inf.obs$formalsmap
#> $aucint.inf.obs$formalsmap$conc
#> [1] "conc.group"
#>
#> $aucint.inf.obs$formalsmap$time
#> [1] "time.group"
#>
#> $aucint.inf.obs$formalsmap$time.dose
#> NULL
#>
#>
#> $aucint.inf.obs$depends
#> [1] "lambda.z" "clast.obs"
#>
#> $aucint.inf.obs$datatype
#> [1] "interval"
#>
#> $aucint.inf.obs$pptestcd_cdisc
#> [1] "AUCINTIS"
#>
#> $aucint.inf.obs$pptest_cdisc
#> [1] "AUCint (based on AUCinf,obs extrapolation)"
#>
#>
#> $aucint.inf.obs.dose
#> $aucint.inf.obs.dose$FUN
#> [1] "pk.calc.aucint.inf.obs"
#>
#> $aucint.inf.obs.dose$values
#> [1] FALSE TRUE
#>
#> $aucint.inf.obs.dose$unit_type
#> [1] "auc"
#>
#> $aucint.inf.obs.dose$pretty_name
#> [1] "AUCint (based on AUCinf,obs extrapolation, dose-aware)"
#>
#> $aucint.inf.obs.dose$desc
#> [1] "The area under the concentration time curve in the interval extrapolating from Tlast to infinity with zeros (matching AUClast) with dose-aware interpolation/extrapolation of concentrations"
#>
#> $aucint.inf.obs.dose$sparse
#> [1] FALSE
#>
#> $aucint.inf.obs.dose$formalsmap
#> $aucint.inf.obs.dose$formalsmap$conc
#> [1] "conc.group"
#>
#> $aucint.inf.obs.dose$formalsmap$time
#> [1] "time.group"
#>
#> $aucint.inf.obs.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#>
#>
#> $aucint.inf.obs.dose$depends
#> [1] "lambda.z" "clast.obs"
#>
#> $aucint.inf.obs.dose$datatype
#> [1] "interval"
#>
#> $aucint.inf.obs.dose$pptestcd_cdisc
#> [1] "AUCINTID"
#>
#> $aucint.inf.obs.dose$pptest_cdisc
#> [1] "AUCint (based on AUCinf,obs extrapolation, dose-aware)"
#>
#>
#> $aucint.inf.pred
#> $aucint.inf.pred$FUN
#> [1] "pk.calc.aucint.inf.pred"
#>
#> $aucint.inf.pred$values
#> [1] FALSE TRUE
#>
#> $aucint.inf.pred$unit_type
#> [1] "auc"
#>
#> $aucint.inf.pred$pretty_name
#> [1] "AUCint (based on AUCinf,pred extrapolation)"
#>
#> $aucint.inf.pred$desc
#> [1] "The area under the concentration time curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUCall)"
#>
#> $aucint.inf.pred$sparse
#> [1] FALSE
#>
#> $aucint.inf.pred$formalsmap
#> $aucint.inf.pred$formalsmap$conc
#> [1] "conc.group"
#>
#> $aucint.inf.pred$formalsmap$time
#> [1] "time.group"
#>
#> $aucint.inf.pred$formalsmap$time.dose
#> NULL
#>
#>
#> $aucint.inf.pred$depends
#> [1] "lambda.z" "clast.pred"
#>
#> $aucint.inf.pred$datatype
#> [1] "interval"
#>
#> $aucint.inf.pred$pptestcd_cdisc
#> [1] "AUCINTIP"
#>
#> $aucint.inf.pred$pptest_cdisc
#> [1] "AUCint (based on AUCinf,pred extrapolation)"
#>
#>
#> $aucint.inf.pred.dose
#> $aucint.inf.pred.dose$FUN
#> [1] "pk.calc.aucint.inf.pred"
#>
#> $aucint.inf.pred.dose$values
#> [1] FALSE TRUE
#>
#> $aucint.inf.pred.dose$unit_type
#> [1] "auc"
#>
#> $aucint.inf.pred.dose$pretty_name
#> [1] "AUCint (based on AUCinf,pred extrapolation, dose-aware)"
#>
#> $aucint.inf.pred.dose$desc
#> [1] "The area under the concentration time curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUCall) with dose-aware interpolation/extrapolation of concentrations"
#>
#> $aucint.inf.pred.dose$sparse
#> [1] FALSE
#>
#> $aucint.inf.pred.dose$formalsmap
#> $aucint.inf.pred.dose$formalsmap$conc
#> [1] "conc.group"
#>
#> $aucint.inf.pred.dose$formalsmap$time
#> [1] "time.group"
#>
#> $aucint.inf.pred.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#>
#>
#> $aucint.inf.pred.dose$depends
#> [1] "lambda.z" "clast.pred"
#>
#> $aucint.inf.pred.dose$datatype
#> [1] "interval"
#>
#> $aucint.inf.pred.dose$pptestcd_cdisc
#> [1] "AUCINTPD"
#>
#> $aucint.inf.pred.dose$pptest_cdisc
#> [1] "AUCint (based on AUCinf,pred extrapolation, dose-aware)"
#>
#>
#> $aumcint.inf.obs
#> $aumcint.inf.obs$FUN
#> [1] "pk.calc.aumcint.inf.obs"
#>
#> $aumcint.inf.obs$values
#> [1] FALSE TRUE
#>
#> $aumcint.inf.obs$unit_type
#> [1] "aumc"
#>
#> $aumcint.inf.obs$pretty_name
#> [1] "AUMCint (based on AUMCinf,obs extrapolation)"
#>
#> $aumcint.inf.obs$desc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with zeros (matching AUMClast)"
#>
#> $aumcint.inf.obs$sparse
#> [1] FALSE
#>
#> $aumcint.inf.obs$formalsmap
#> $aumcint.inf.obs$formalsmap$conc
#> [1] "conc.group"
#>
#> $aumcint.inf.obs$formalsmap$time
#> [1] "time.group"
#>
#> $aumcint.inf.obs$formalsmap$time.dose
#> NULL
#>
#>
#> $aumcint.inf.obs$depends
#> [1] "lambda.z" "clast.obs"
#>
#> $aumcint.inf.obs$datatype
#> [1] "interval"
#>
#> $aumcint.inf.obs$pptestcd_cdisc
#> [1] "aumcint.inf.obs"
#>
#> $aumcint.inf.obs$pptest_cdisc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with zeros (matching AUMClast)"
#>
#>
#> $aumcint.inf.obs.dose
#> $aumcint.inf.obs.dose$FUN
#> [1] "pk.calc.aumcint.inf.obs"
#>
#> $aumcint.inf.obs.dose$values
#> [1] FALSE TRUE
#>
#> $aumcint.inf.obs.dose$unit_type
#> [1] "aumc"
#>
#> $aumcint.inf.obs.dose$pretty_name
#> [1] "AUMCint (based on AUMCinf,obs extrapolation, dose-aware)"
#>
#> $aumcint.inf.obs.dose$desc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with zeros (matching AUMClast) with dose-aware interpolation/extrapolation of concentrations"
#>
#> $aumcint.inf.obs.dose$sparse
#> [1] FALSE
#>
#> $aumcint.inf.obs.dose$formalsmap
#> $aumcint.inf.obs.dose$formalsmap$conc
#> [1] "conc.group"
#>
#> $aumcint.inf.obs.dose$formalsmap$time
#> [1] "time.group"
#>
#> $aumcint.inf.obs.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#>
#>
#> $aumcint.inf.obs.dose$depends
#> [1] "lambda.z" "clast.obs"
#>
#> $aumcint.inf.obs.dose$datatype
#> [1] "interval"
#>
#> $aumcint.inf.obs.dose$pptestcd_cdisc
#> [1] "aumcint.inf.obs.dose"
#>
#> $aumcint.inf.obs.dose$pptest_cdisc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with zeros (matching AUMClast) with dose-aware interpolation/extrapolation of concentrations"
#>
#>
#> $aumcint.inf.pred
#> $aumcint.inf.pred$FUN
#> [1] "pk.calc.aumcint.inf.pred"
#>
#> $aumcint.inf.pred$values
#> [1] FALSE TRUE
#>
#> $aumcint.inf.pred$unit_type
#> [1] "aumc"
#>
#> $aumcint.inf.pred$pretty_name
#> [1] "AUMCint (based on AUMCinf,pred extrapolation)"
#>
#> $aumcint.inf.pred$desc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUMCall)"
#>
#> $aumcint.inf.pred$sparse
#> [1] FALSE
#>
#> $aumcint.inf.pred$formalsmap
#> $aumcint.inf.pred$formalsmap$conc
#> [1] "conc.group"
#>
#> $aumcint.inf.pred$formalsmap$time
#> [1] "time.group"
#>
#> $aumcint.inf.pred$formalsmap$time.dose
#> NULL
#>
#>
#> $aumcint.inf.pred$depends
#> [1] "lambda.z" "clast.pred"
#>
#> $aumcint.inf.pred$datatype
#> [1] "interval"
#>
#> $aumcint.inf.pred$pptestcd_cdisc
#> [1] "aumcint.inf.pred"
#>
#> $aumcint.inf.pred$pptest_cdisc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUMCall)"
#>
#>
#> $aumcint.inf.pred.dose
#> $aumcint.inf.pred.dose$FUN
#> [1] "pk.calc.aumcint.inf.pred"
#>
#> $aumcint.inf.pred.dose$values
#> [1] FALSE TRUE
#>
#> $aumcint.inf.pred.dose$unit_type
#> [1] "aumc"
#>
#> $aumcint.inf.pred.dose$pretty_name
#> [1] "AUMCint (based on AUMCinf,pred extrapolation, dose-aware)"
#>
#> $aumcint.inf.pred.dose$desc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUMCall) with dose-aware interpolation/extrapolation of concentrations"
#>
#> $aumcint.inf.pred.dose$sparse
#> [1] FALSE
#>
#> $aumcint.inf.pred.dose$formalsmap
#> $aumcint.inf.pred.dose$formalsmap$conc
#> [1] "conc.group"
#>
#> $aumcint.inf.pred.dose$formalsmap$time
#> [1] "time.group"
#>
#> $aumcint.inf.pred.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#>
#>
#> $aumcint.inf.pred.dose$depends
#> [1] "lambda.z" "clast.pred"
#>
#> $aumcint.inf.pred.dose$datatype
#> [1] "interval"
#>
#> $aumcint.inf.pred.dose$pptestcd_cdisc
#> [1] "aumcint.inf.pred.dose"
#>
#> $aumcint.inf.pred.dose$pptest_cdisc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUMCall) with dose-aware interpolation/extrapolation of concentrations"
#>
#>
#> $aucivinf.obs
#> $aucivinf.obs$FUN
#> [1] "pk.calc.auciv"
#>
#> $aucivinf.obs$values
#> [1] FALSE TRUE
#>
#> $aucivinf.obs$unit_type
#> [1] "auc"
#>
#> $aucivinf.obs$pretty_name
#> [1] "AUCinf,obs (IV dosing)"
#>
#> $aucivinf.obs$desc
#> [1] "The AUCinf,obs calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#>
#> $aucivinf.obs$sparse
#> [1] FALSE
#>
#> $aucivinf.obs$formalsmap
#> $aucivinf.obs$formalsmap$auc
#> [1] "aucinf.obs"
#>
#>
#> $aucivinf.obs$depends
#> [1] "aucinf.obs" "c0"
#>
#> $aucivinf.obs$datatype
#> [1] "interval"
#>
#> $aucivinf.obs$pptestcd_cdisc
#> [1] "AUCIVIS"
#>
#> $aucivinf.obs$pptest_cdisc
#> [1] "AUCinf,obs (IV dosing)"
#>
#>
#> $aucivinf.pred
#> $aucivinf.pred$FUN
#> [1] "pk.calc.auciv"
#>
#> $aucivinf.pred$values
#> [1] FALSE TRUE
#>
#> $aucivinf.pred$unit_type
#> [1] "auc"
#>
#> $aucivinf.pred$pretty_name
#> [1] "AUCinf,pred (IV dosing)"
#>
#> $aucivinf.pred$desc
#> [1] "The AUCinf,pred calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#>
#> $aucivinf.pred$sparse
#> [1] FALSE
#>
#> $aucivinf.pred$formalsmap
#> $aucivinf.pred$formalsmap$auc
#> [1] "aucinf.pred"
#>
#>
#> $aucivinf.pred$depends
#> [1] "aucinf.pred" "c0"
#>
#> $aucivinf.pred$datatype
#> [1] "interval"
#>
#> $aucivinf.pred$pptestcd_cdisc
#> [1] "AUCIVIP"
#>
#> $aucivinf.pred$pptest_cdisc
#> [1] "AUCinf,pred (IV dosing)"
#>
#>
#> $aucivpbextinf.obs
#> $aucivpbextinf.obs$FUN
#> [1] "pk.calc.auciv_pbext"
#>
#> $aucivpbextinf.obs$values
#> [1] FALSE TRUE
#>
#> $aucivpbextinf.obs$unit_type
#> [1] "%"
#>
#> $aucivpbextinf.obs$pretty_name
#> [1] "AUCbext (based on AUCinf,obs)"
#>
#> $aucivpbextinf.obs$desc
#> [1] "The back-extrapolation percent for intravenous dosing based on AUCinf,obs"
#>
#> $aucivpbextinf.obs$sparse
#> [1] FALSE
#>
#> $aucivpbextinf.obs$formalsmap
#> $aucivpbextinf.obs$formalsmap$auc
#> [1] "aucinf.obs"
#>
#> $aucivpbextinf.obs$formalsmap$auciv
#> [1] "aucivinf.obs"
#>
#>
#> $aucivpbextinf.obs$depends
#> [1] "aucinf.obs" "aucivinf.obs"
#>
#> $aucivpbextinf.obs$datatype
#> [1] "interval"
#>
#> $aucivpbextinf.obs$pptestcd_cdisc
#> [1] "AUCIVPEI"
#>
#> $aucivpbextinf.obs$pptest_cdisc
#> [1] "AUCbext (based on AUCinf,obs)"
#>
#>
#> $aucivpbextinf.pred
#> $aucivpbextinf.pred$FUN
#> [1] "pk.calc.auciv_pbext"
#>
#> $aucivpbextinf.pred$values
#> [1] FALSE TRUE
#>
#> $aucivpbextinf.pred$unit_type
#> [1] "%"
#>
#> $aucivpbextinf.pred$pretty_name
#> [1] "AUCbext (based on AUCinf,pred)"
#>
#> $aucivpbextinf.pred$desc
#> [1] "The back-extrapolation percent for intravenous dosing based on AUCinf,pred"
#>
#> $aucivpbextinf.pred$sparse
#> [1] FALSE
#>
#> $aucivpbextinf.pred$formalsmap
#> $aucivpbextinf.pred$formalsmap$auc
#> [1] "aucinf.pred"
#>
#> $aucivpbextinf.pred$formalsmap$auciv
#> [1] "aucivinf.pred"
#>
#>
#> $aucivpbextinf.pred$depends
#> [1] "aucinf.pred" "aucivinf.pred"
#>
#> $aucivpbextinf.pred$datatype
#> [1] "interval"
#>
#> $aucivpbextinf.pred$pptestcd_cdisc
#> [1] "AUCIVPEP"
#>
#> $aucivpbextinf.pred$pptest_cdisc
#> [1] "AUCbext (based on AUCinf,pred)"
#>
#>
#> $aumcivinf.obs
#> $aumcivinf.obs$FUN
#> [1] "pk.calc.aumciv"
#>
#> $aumcivinf.obs$values
#> [1] FALSE TRUE
#>
#> $aumcivinf.obs$unit_type
#> [1] "aumc"
#>
#> $aumcivinf.obs$pretty_name
#> [1] "AUMCinf,obs (IV dosing)"
#>
#> $aumcivinf.obs$desc
#> [1] "The AUMCinf,obs calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#>
#> $aumcivinf.obs$sparse
#> [1] FALSE
#>
#> $aumcivinf.obs$formalsmap
#> $aumcivinf.obs$formalsmap$aumc
#> [1] "aumcinf.obs"
#>
#>
#> $aumcivinf.obs$depends
#> [1] "aumcinf.obs" "c0"
#>
#> $aumcivinf.obs$datatype
#> [1] "interval"
#>
#> $aumcivinf.obs$pptestcd_cdisc
#> [1] "aumcivinf.obs"
#>
#> $aumcivinf.obs$pptest_cdisc
#> [1] "The AUMCinf,obs calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#>
#>
#> $aumcivinf.pred
#> $aumcivinf.pred$FUN
#> [1] "pk.calc.aumciv"
#>
#> $aumcivinf.pred$values
#> [1] FALSE TRUE
#>
#> $aumcivinf.pred$unit_type
#> [1] "aumc"
#>
#> $aumcivinf.pred$pretty_name
#> [1] "AUMCinf,pred (IV dosing)"
#>
#> $aumcivinf.pred$desc
#> [1] "The AUMCinf,pred calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#>
#> $aumcivinf.pred$sparse
#> [1] FALSE
#>
#> $aumcivinf.pred$formalsmap
#> $aumcivinf.pred$formalsmap$aumc
#> [1] "aumcinf.pred"
#>
#>
#> $aumcivinf.pred$depends
#> [1] "aumcinf.pred" "c0"
#>
#> $aumcivinf.pred$datatype
#> [1] "interval"
#>
#> $aumcivinf.pred$pptestcd_cdisc
#> [1] "aumcivinf.pred"
#>
#> $aumcivinf.pred$pptest_cdisc
#> [1] "The AUMCinf,pred calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#>
#>
#> $aucpext.obs
#> $aucpext.obs$FUN
#> [1] "pk.calc.aucpext"
#>
#> $aucpext.obs$values
#> [1] FALSE TRUE
#>
#> $aucpext.obs$unit_type
#> [1] "%"
#>
#> $aucpext.obs$pretty_name
#> [1] "AUCpext (based on AUCinf,obs)"
#>
#> $aucpext.obs$desc
#> [1] "Percent of the AUCinf that is extrapolated after Tlast calculated from the observed Clast"
#>
#> $aucpext.obs$sparse
#> [1] FALSE
#>
#> $aucpext.obs$formalsmap
#> $aucpext.obs$formalsmap$aucinf
#> [1] "aucinf.obs"
#>
#>
#> $aucpext.obs$depends
#> [1] "auclast" "aucinf.obs"
#>
#> $aucpext.obs$datatype
#> [1] "interval"
#>
#> $aucpext.obs$pptestcd_cdisc
#> [1] "AUCPEO"
#>
#> $aucpext.obs$pptest_cdisc
#> [1] "AUC %Extrapolation Obs"
#>
#>
#> $aucpext.pred
#> $aucpext.pred$FUN
#> [1] "pk.calc.aucpext"
#>
#> $aucpext.pred$values
#> [1] FALSE TRUE
#>
#> $aucpext.pred$unit_type
#> [1] "%"
#>
#> $aucpext.pred$pretty_name
#> [1] "AUCpext (based on AUCinf,pred)"
#>
#> $aucpext.pred$desc
#> [1] "Percent of the AUCinf that is extrapolated after Tlast calculated from the predicted Clast"
#>
#> $aucpext.pred$sparse
#> [1] FALSE
#>
#> $aucpext.pred$formalsmap
#> $aucpext.pred$formalsmap$aucinf
#> [1] "aucinf.pred"
#>
#>
#> $aucpext.pred$depends
#> [1] "auclast" "aucinf.pred"
#>
#> $aucpext.pred$datatype
#> [1] "interval"
#>
#> $aucpext.pred$pptestcd_cdisc
#> [1] "AUCPEP"
#>
#> $aucpext.pred$pptest_cdisc
#> [1] "AUC %Extrapolation Pred"
#>
#>
#> $kel.iv.all
#> $kel.iv.all$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.iv.all$values
#> [1] FALSE TRUE
#>
#> $kel.iv.all$unit_type
#> [1] "inverse_time"
#>
#> $kel.iv.all$pretty_name
#> [1] "Kel (for IV dosing, based on AUCall)"
#>
#> $kel.iv.all$desc
#> [1] "Elimination rate (as calculated from the MRTiv.all))"
#>
#> $kel.iv.all$sparse
#> [1] FALSE
#>
#> $kel.iv.all$formalsmap
#> $kel.iv.all$formalsmap$mrt
#> [1] "mrt.iv.all"
#>
#>
#> $kel.iv.all$depends
#> [1] "mrt.iv.all"
#>
#> $kel.iv.all$datatype
#> [1] "interval"
#>
#> $kel.iv.all$pptestcd_cdisc
#> [1] "kel.iv.all"
#>
#> $kel.iv.all$pptest_cdisc
#> [1] "Elimination rate (as calculated from the MRTiv.all))"
#>
#>
#> $kel.ivint.all
#> $kel.ivint.all$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.ivint.all$values
#> [1] FALSE TRUE
#>
#> $kel.ivint.all$unit_type
#> [1] "inverse_time"
#>
#> $kel.ivint.all$pretty_name
#> [1] "Kel (IV dose interval, based on AUCint.all)"
#>
#> $kel.ivint.all$desc
#> [1] "Elimination rate (as calculated from the MRTivint.all)"
#>
#> $kel.ivint.all$sparse
#> [1] FALSE
#>
#> $kel.ivint.all$formalsmap
#> $kel.ivint.all$formalsmap$mrt
#> [1] "mrt.ivint.all"
#>
#>
#> $kel.ivint.all$depends
#> [1] "mrt.ivint.all"
#>
#> $kel.ivint.all$datatype
#> [1] "interval"
#>
#> $kel.ivint.all$pptestcd_cdisc
#> [1] "kel.ivint.all"
#>
#> $kel.ivint.all$pptest_cdisc
#> [1] "Elimination rate (as calculated from the MRTivint.all)"
#>
#>
#> $kel.ivint.last
#> $kel.ivint.last$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.ivint.last$values
#> [1] FALSE TRUE
#>
#> $kel.ivint.last$unit_type
#> [1] "inverse_time"
#>
#> $kel.ivint.last$pretty_name
#> [1] "Kel (IV dose interval, based on AUCint.last)"
#>
#> $kel.ivint.last$desc
#> [1] "Elimination rate (as calculated from the MRTivint.last)"
#>
#> $kel.ivint.last$sparse
#> [1] FALSE
#>
#> $kel.ivint.last$formalsmap
#> $kel.ivint.last$formalsmap$mrt
#> [1] "mrt.ivint.last"
#>
#>
#> $kel.ivint.last$depends
#> [1] "mrt.ivint.last"
#>
#> $kel.ivint.last$datatype
#> [1] "interval"
#>
#> $kel.ivint.last$pptestcd_cdisc
#> [1] "kel.ivint.last"
#>
#> $kel.ivint.last$pptest_cdisc
#> [1] "Elimination rate (as calculated from the MRTivint.last)"
#>
#>
#> $kel.sparse.last
#> $kel.sparse.last$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.sparse.last$values
#> [1] FALSE TRUE
#>
#> $kel.sparse.last$unit_type
#> [1] "inverse_time"
#>
#> $kel.sparse.last$pretty_name
#> [1] "Kel (for sparse data, based on AUClast)"
#>
#> $kel.sparse.last$desc
#> [1] "Elimination rate (as calculated from the MRTsparse.last)"
#>
#> $kel.sparse.last$sparse
#> [1] TRUE
#>
#> $kel.sparse.last$formalsmap
#> $kel.sparse.last$formalsmap$mrt
#> [1] "mrt.sparse.last"
#>
#>
#> $kel.sparse.last$depends
#> [1] "mrt.sparse.last"
#>
#> $kel.sparse.last$datatype
#> [1] "interval"
#>
#> $kel.sparse.last$pptestcd_cdisc
#> [1] "kel.sparse.last"
#>
#> $kel.sparse.last$pptest_cdisc
#> [1] "Elimination rate (as calculated from the MRTsparse.last)"
#>
#>
#> $cl.obs
#> $cl.obs$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.obs$values
#> [1] FALSE TRUE
#>
#> $cl.obs$unit_type
#> [1] "clearance"
#>
#> $cl.obs$pretty_name
#> [1] "CL (based on AUCinf,obs)"
#>
#> $cl.obs$desc
#> [1] "Clearance or observed oral clearance calculated with observed Clast"
#>
#> $cl.obs$sparse
#> [1] FALSE
#>
#> $cl.obs$formalsmap
#> $cl.obs$formalsmap$auc
#> [1] "aucinf.obs"
#>
#>
#> $cl.obs$depends
#> [1] "aucinf.obs"
#>
#> $cl.obs$datatype
#> [1] "interval"
#>
#> $cl.obs$pptestcd_cdisc
#> $cl.obs$pptestcd_cdisc$route
#> $cl.obs$pptestcd_cdisc$route$extravascular
#> [1] "CLF/FO"
#>
#> $cl.obs$pptestcd_cdisc$route$intravascular
#> [1] "CLO"
#>
#>
#>
#> $cl.obs$pptest_cdisc
#> $cl.obs$pptest_cdisc$route
#> $cl.obs$pptest_cdisc$route$extravascular
#> [1] "Total CL Obs by F"
#>
#> $cl.obs$pptest_cdisc$route$intravascular
#> [1] "Total CL Obs"
#>
#>
#>
#>
#> $cl.pred
#> $cl.pred$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.pred$values
#> [1] FALSE TRUE
#>
#> $cl.pred$unit_type
#> [1] "clearance"
#>
#> $cl.pred$pretty_name
#> [1] "CL (based on AUCinf,pred)"
#>
#> $cl.pred$desc
#> [1] "Clearance or observed oral clearance calculated with predicted Clast"
#>
#> $cl.pred$sparse
#> [1] FALSE
#>
#> $cl.pred$formalsmap
#> $cl.pred$formalsmap$auc
#> [1] "aucinf.pred"
#>
#>
#> $cl.pred$depends
#> [1] "aucinf.pred"
#>
#> $cl.pred$datatype
#> [1] "interval"
#>
#> $cl.pred$pptestcd_cdisc
#> $cl.pred$pptestcd_cdisc$route
#> $cl.pred$pptestcd_cdisc$route$extravascular
#> [1] "CLF/FP"
#>
#> $cl.pred$pptestcd_cdisc$route$intravascular
#> [1] "CLP"
#>
#>
#>
#> $cl.pred$pptest_cdisc
#> $cl.pred$pptest_cdisc$route
#> $cl.pred$pptest_cdisc$route$extravascular
#> [1] "Total CL Pred by F"
#>
#> $cl.pred$pptest_cdisc$route$intravascular
#> [1] "Total CL Pred"
#>
#>
#>
#>
#> $cl.int.inf.obs
#> $cl.int.inf.obs$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.int.inf.obs$values
#> [1] FALSE TRUE
#>
#> $cl.int.inf.obs$unit_type
#> [1] "clearance"
#>
#> $cl.int.inf.obs$pretty_name
#> [1] "CL (based on AUCint.inf.obs)"
#>
#> $cl.int.inf.obs$desc
#> [1] "Clearance or observed oral clearance calculated with AUCint.inf.obs"
#>
#> $cl.int.inf.obs$sparse
#> [1] FALSE
#>
#> $cl.int.inf.obs$formalsmap
#> $cl.int.inf.obs$formalsmap$auc
#> [1] "aucint.inf.obs"
#>
#>
#> $cl.int.inf.obs$depends
#> [1] "aucint.inf.obs"
#>
#> $cl.int.inf.obs$datatype
#> [1] "interval"
#>
#> $cl.int.inf.obs$pptestcd_cdisc
#> [1] "cl.int.inf.obs"
#>
#> $cl.int.inf.obs$pptest_cdisc
#> [1] "Clearance or observed oral clearance calculated with AUCint.inf.obs"
#>
#>
#> $cl.int.inf.pred
#> $cl.int.inf.pred$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.int.inf.pred$values
#> [1] FALSE TRUE
#>
#> $cl.int.inf.pred$unit_type
#> [1] "clearance"
#>
#> $cl.int.inf.pred$pretty_name
#> [1] "CL (based on AUCint.inf.pred)"
#>
#> $cl.int.inf.pred$desc
#> [1] "Clearance or observed oral clearance calculated with AUCint.inf.pred"
#>
#> $cl.int.inf.pred$sparse
#> [1] FALSE
#>
#> $cl.int.inf.pred$formalsmap
#> $cl.int.inf.pred$formalsmap$auc
#> [1] "aucint.inf.pred"
#>
#>
#> $cl.int.inf.pred$depends
#> [1] "aucint.inf.pred"
#>
#> $cl.int.inf.pred$datatype
#> [1] "interval"
#>
#> $cl.int.inf.pred$pptestcd_cdisc
#> [1] "cl.int.inf.pred"
#>
#> $cl.int.inf.pred$pptest_cdisc
#> [1] "Clearance or observed oral clearance calculated with AUCint.inf.pred"
#>
#>
#> $cl.iv.obs
#> $cl.iv.obs$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.iv.obs$values
#> [1] FALSE TRUE
#>
#> $cl.iv.obs$unit_type
#> [1] "clearance"
#>
#> $cl.iv.obs$pretty_name
#> [1] "CL (for IV dosing, based on AUCinf,obs)"
#>
#> $cl.iv.obs$desc
#> [1] "Clearance for intravenous dosing calculated with AUCinf,obs"
#>
#> $cl.iv.obs$sparse
#> [1] FALSE
#>
#> $cl.iv.obs$formalsmap
#> $cl.iv.obs$formalsmap$auc
#> [1] "aucivinf.obs"
#>
#>
#> $cl.iv.obs$depends
#> [1] "aucivinf.obs"
#>
#> $cl.iv.obs$datatype
#> [1] "interval"
#>
#> $cl.iv.obs$pptestcd_cdisc
#> [1] "cl.iv.obs"
#>
#> $cl.iv.obs$pptest_cdisc
#> [1] "Clearance for intravenous dosing calculated with AUCinf,obs"
#>
#>
#> $cl.iv.pred
#> $cl.iv.pred$FUN
#> [1] "pk.calc.cl"
#>
#> $cl.iv.pred$values
#> [1] FALSE TRUE
#>
#> $cl.iv.pred$unit_type
#> [1] "clearance"
#>
#> $cl.iv.pred$pretty_name
#> [1] "CL (for IV dosing, based on AUCinf,pred)"
#>
#> $cl.iv.pred$desc
#> [1] "Clearance for intravenous dosing calculated with AUCinf,pred"
#>
#> $cl.iv.pred$sparse
#> [1] FALSE
#>
#> $cl.iv.pred$formalsmap
#> $cl.iv.pred$formalsmap$auc
#> [1] "aucivinf.pred"
#>
#>
#> $cl.iv.pred$depends
#> [1] "aucivinf.pred"
#>
#> $cl.iv.pred$datatype
#> [1] "interval"
#>
#> $cl.iv.pred$pptestcd_cdisc
#> [1] "cl.iv.pred"
#>
#> $cl.iv.pred$pptest_cdisc
#> [1] "Clearance for intravenous dosing calculated with AUCinf,pred"
#>
#>
#> $mrt.obs
#> $mrt.obs$FUN
#> [1] "pk.calc.mrt"
#>
#> $mrt.obs$values
#> [1] FALSE TRUE
#>
#> $mrt.obs$unit_type
#> [1] "time"
#>
#> $mrt.obs$pretty_name
#> [1] "MRT (based on AUCinf,obs)"
#>
#> $mrt.obs$desc
#> [1] "The mean residence time to infinity using observed Clast"
#>
#> $mrt.obs$sparse
#> [1] FALSE
#>
#> $mrt.obs$formalsmap
#> $mrt.obs$formalsmap$auc
#> [1] "aucinf.obs"
#>
#> $mrt.obs$formalsmap$aumc
#> [1] "aumcinf.obs"
#>
#>
#> $mrt.obs$depends
#> [1] "aucinf.obs" "aumcinf.obs"
#>
#> $mrt.obs$datatype
#> [1] "interval"
#>
#> $mrt.obs$pptestcd_cdisc
#> $mrt.obs$pptestcd_cdisc$route
#> $mrt.obs$pptestcd_cdisc$route$extravascular
#> [1] "MRTEVFO"
#>
#> $mrt.obs$pptestcd_cdisc$route$intravascular
#> [1] "MRTICFO"
#>
#>
#>
#> $mrt.obs$pptest_cdisc
#> $mrt.obs$pptest_cdisc$route
#> $mrt.obs$pptest_cdisc$route$extravascular
#> [1] "MRT Extravasc Infinity Obs"
#>
#> $mrt.obs$pptest_cdisc$route$intravascular
#> [1] "MRT IV Cont Inf Infinity Obs"
#>
#>
#>
#>
#> $mrt.pred
#> $mrt.pred$FUN
#> [1] "pk.calc.mrt"
#>
#> $mrt.pred$values
#> [1] FALSE TRUE
#>
#> $mrt.pred$unit_type
#> [1] "time"
#>
#> $mrt.pred$pretty_name
#> [1] "MRT (based on AUCinf,pred)"
#>
#> $mrt.pred$desc
#> [1] "The mean residence time to infinity using predicted Clast"
#>
#> $mrt.pred$sparse
#> [1] FALSE
#>
#> $mrt.pred$formalsmap
#> $mrt.pred$formalsmap$auc
#> [1] "aucinf.pred"
#>
#> $mrt.pred$formalsmap$aumc
#> [1] "aumcinf.pred"
#>
#>
#> $mrt.pred$depends
#> [1] "aucinf.pred" "aumcinf.pred"
#>
#> $mrt.pred$datatype
#> [1] "interval"
#>
#> $mrt.pred$pptestcd_cdisc
#> $mrt.pred$pptestcd_cdisc$route
#> $mrt.pred$pptestcd_cdisc$route$extravascular
#> [1] "MRTEVFP"
#>
#> $mrt.pred$pptestcd_cdisc$route$intravascular
#> [1] "MRTICFP"
#>
#>
#>
#> $mrt.pred$pptest_cdisc
#> $mrt.pred$pptest_cdisc$route
#> $mrt.pred$pptest_cdisc$route$extravascular
#> [1] "MRT Extravasc Infinity Pred"
#>
#> $mrt.pred$pptest_cdisc$route$intravascular
#> [1] "MRT IV Cont Inf Infinity Pred"
#>
#>
#>
#>
#> $mrt.int.inf.obs
#> $mrt.int.inf.obs$FUN
#> [1] "pk.calc.mrt"
#>
#> $mrt.int.inf.obs$values
#> [1] FALSE TRUE
#>
#> $mrt.int.inf.obs$unit_type
#> [1] "time"
#>
#> $mrt.int.inf.obs$pretty_name
#> [1] "MRT (based on AUCint.inf.obs)"
#>
#> $mrt.int.inf.obs$desc
#> [1] "Mean residence time over interval calculated with AUCint.inf.obs/AUMCint.inf.obs"
#>
#> $mrt.int.inf.obs$sparse
#> [1] FALSE
#>
#> $mrt.int.inf.obs$formalsmap
#> $mrt.int.inf.obs$formalsmap$auc
#> [1] "aucint.inf.obs"
#>
#> $mrt.int.inf.obs$formalsmap$aumc
#> [1] "aumcint.inf.obs"
#>
#>
#> $mrt.int.inf.obs$depends
#> [1] "aucint.inf.obs" "aumcint.inf.obs"
#>
#> $mrt.int.inf.obs$datatype
#> [1] "interval"
#>
#> $mrt.int.inf.obs$pptestcd_cdisc
#> [1] "mrt.int.inf.obs"
#>
#> $mrt.int.inf.obs$pptest_cdisc
#> [1] "Mean residence time over interval calculated with AUCint.inf.obs/AUMCint.inf.obs"
#>
#>
#> $mrt.int.inf.pred
#> $mrt.int.inf.pred$FUN
#> [1] "pk.calc.mrt"
#>
#> $mrt.int.inf.pred$values
#> [1] FALSE TRUE
#>
#> $mrt.int.inf.pred$unit_type
#> [1] "time"
#>
#> $mrt.int.inf.pred$pretty_name
#> [1] "MRT (based on AUCint.inf.pred)"
#>
#> $mrt.int.inf.pred$desc
#> [1] "Mean residence time over interval calculated with AUCint.inf.pred/AUMCint.inf.pred"
#>
#> $mrt.int.inf.pred$sparse
#> [1] FALSE
#>
#> $mrt.int.inf.pred$formalsmap
#> $mrt.int.inf.pred$formalsmap$auc
#> [1] "aucint.inf.pred"
#>
#> $mrt.int.inf.pred$formalsmap$aumc
#> [1] "aumcint.inf.pred"
#>
#>
#> $mrt.int.inf.pred$depends
#> [1] "aucint.inf.pred" "aumcint.inf.pred"
#>
#> $mrt.int.inf.pred$datatype
#> [1] "interval"
#>
#> $mrt.int.inf.pred$pptestcd_cdisc
#> [1] "mrt.int.inf.pred"
#>
#> $mrt.int.inf.pred$pptest_cdisc
#> [1] "Mean residence time over interval calculated with AUCint.inf.pred/AUMCint.inf.pred"
#>
#>
#> $mrt.iv.obs
#> $mrt.iv.obs$FUN
#> [1] "pk.calc.mrt.iv"
#>
#> $mrt.iv.obs$values
#> [1] FALSE TRUE
#>
#> $mrt.iv.obs$unit_type
#> [1] "time"
#>
#> $mrt.iv.obs$pretty_name
#> [1] "MRT (for IV dosing, based on AUCinf,obs)"
#>
#> $mrt.iv.obs$desc
#> [1] "The mean residence time to infinity using observed Clast correcting for dosing duration"
#>
#> $mrt.iv.obs$sparse
#> [1] FALSE
#>
#> $mrt.iv.obs$formalsmap
#> $mrt.iv.obs$formalsmap$auc
#> [1] "aucinf.obs"
#>
#> $mrt.iv.obs$formalsmap$aumc
#> [1] "aumcinf.obs"
#>
#>
#> $mrt.iv.obs$depends
#> [1] "aucinf.obs" "aumcinf.obs"
#>
#> $mrt.iv.obs$datatype
#> [1] "interval"
#>
#> $mrt.iv.obs$pptestcd_cdisc
#> [1] "MRTIBIFO"
#>
#> $mrt.iv.obs$pptest_cdisc
#> [1] "MRT Intravasc Infinity Obs"
#>
#>
#> $mrt.iv.pred
#> $mrt.iv.pred$FUN
#> [1] "pk.calc.mrt.iv"
#>
#> $mrt.iv.pred$values
#> [1] FALSE TRUE
#>
#> $mrt.iv.pred$unit_type
#> [1] "time"
#>
#> $mrt.iv.pred$pretty_name
#> [1] "MRT (for IV dosing, based on AUCinf,pred)"
#>
#> $mrt.iv.pred$desc
#> [1] "The mean residence time to infinity using predicted Clast correcting for dosing duration"
#>
#> $mrt.iv.pred$sparse
#> [1] FALSE
#>
#> $mrt.iv.pred$formalsmap
#> $mrt.iv.pred$formalsmap$auc
#> [1] "aucinf.pred"
#>
#> $mrt.iv.pred$formalsmap$aumc
#> [1] "aumcinf.pred"
#>
#>
#> $mrt.iv.pred$depends
#> [1] "aucinf.pred" "aumcinf.pred"
#>
#> $mrt.iv.pred$datatype
#> [1] "interval"
#>
#> $mrt.iv.pred$pptestcd_cdisc
#> [1] "MRTIBIFP"
#>
#> $mrt.iv.pred$pptest_cdisc
#> [1] "MRT Intravasc Infinity Pred"
#>
#>
#> $mrt.md.obs
#> $mrt.md.obs$FUN
#> [1] "pk.calc.mrt.md"
#>
#> $mrt.md.obs$values
#> [1] FALSE TRUE
#>
#> $mrt.md.obs$unit_type
#> [1] "time"
#>
#> $mrt.md.obs$pretty_name
#> [1] "MRT (for multiple dosing, based on AUCinf,obs)"
#>
#> $mrt.md.obs$desc
#> [1] "The mean residence time with multiple dosing and nonlinear kinetics using observed Clast"
#>
#> $mrt.md.obs$sparse
#> [1] FALSE
#>
#> $mrt.md.obs$formalsmap
#> $mrt.md.obs$formalsmap$auctau
#> [1] "auclast"
#>
#> $mrt.md.obs$formalsmap$aumctau
#> [1] "aumclast"
#>
#> $mrt.md.obs$formalsmap$aucinf
#> [1] "aucinf.obs"
#>
#>
#> $mrt.md.obs$depends
#> [1] "auclast" "aumclast" "aucinf.obs"
#>
#> $mrt.md.obs$datatype
#> [1] "interval"
#>
#> $mrt.md.obs$pptestcd_cdisc
#> [1] "MRTMDO"
#>
#> $mrt.md.obs$pptest_cdisc
#> [1] "MRT (for multiple dosing, based on AUCinf,obs)"
#>
#>
#> $mrt.md.pred
#> $mrt.md.pred$FUN
#> [1] "pk.calc.mrt.md"
#>
#> $mrt.md.pred$values
#> [1] FALSE TRUE
#>
#> $mrt.md.pred$unit_type
#> [1] "time"
#>
#> $mrt.md.pred$pretty_name
#> [1] "MRT (for multiple dosing, based on AUCinf,pred)"
#>
#> $mrt.md.pred$desc
#> [1] "The mean residence time with multiple dosing and nonlinear kinetics using predicted Clast"
#>
#> $mrt.md.pred$sparse
#> [1] FALSE
#>
#> $mrt.md.pred$formalsmap
#> $mrt.md.pred$formalsmap$auctau
#> [1] "auclast"
#>
#> $mrt.md.pred$formalsmap$aumctau
#> [1] "aumclast"
#>
#> $mrt.md.pred$formalsmap$aucinf
#> [1] "aucinf.pred"
#>
#>
#> $mrt.md.pred$depends
#> [1] "auclast" "aumclast" "aucinf.pred"
#>
#> $mrt.md.pred$datatype
#> [1] "interval"
#>
#> $mrt.md.pred$pptestcd_cdisc
#> [1] "MRTMDP"
#>
#> $mrt.md.pred$pptest_cdisc
#> [1] "MRT (for multiple dosing, based on AUCinf,pred)"
#>
#>
#> $vz.obs
#> $vz.obs$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.obs$values
#> [1] FALSE TRUE
#>
#> $vz.obs$unit_type
#> [1] "volume"
#>
#> $vz.obs$pretty_name
#> [1] "Vz (based on AUCinf,obs)"
#>
#> $vz.obs$desc
#> [1] "The terminal volume of distribution using observed Clast"
#>
#> $vz.obs$sparse
#> [1] FALSE
#>
#> $vz.obs$formalsmap
#> $vz.obs$formalsmap$cl
#> [1] "cl.obs"
#>
#>
#> $vz.obs$depends
#> [1] "cl.obs" "lambda.z"
#>
#> $vz.obs$datatype
#> [1] "interval"
#>
#> $vz.obs$pptestcd_cdisc
#> $vz.obs$pptestcd_cdisc$route
#> $vz.obs$pptestcd_cdisc$route$extravascular
#> [1] "VZF/FO"
#>
#> $vz.obs$pptestcd_cdisc$route$intravascular
#> [1] "VZO"
#>
#>
#>
#> $vz.obs$pptest_cdisc
#> $vz.obs$pptest_cdisc$route
#> $vz.obs$pptest_cdisc$route$extravascular
#> [1] "Vz by F Obs"
#>
#> $vz.obs$pptest_cdisc$route$intravascular
#> [1] "Vz Obs"
#>
#>
#>
#>
#> $vz.pred
#> $vz.pred$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.pred$values
#> [1] FALSE TRUE
#>
#> $vz.pred$unit_type
#> [1] "volume"
#>
#> $vz.pred$pretty_name
#> [1] "Vz (based on AUCinf,pred)"
#>
#> $vz.pred$desc
#> [1] "The terminal volume of distribution using predicted Clast"
#>
#> $vz.pred$sparse
#> [1] FALSE
#>
#> $vz.pred$formalsmap
#> $vz.pred$formalsmap$cl
#> [1] "cl.pred"
#>
#>
#> $vz.pred$depends
#> [1] "cl.pred" "lambda.z"
#>
#> $vz.pred$datatype
#> [1] "interval"
#>
#> $vz.pred$pptestcd_cdisc
#> $vz.pred$pptestcd_cdisc$route
#> $vz.pred$pptestcd_cdisc$route$extravascular
#> [1] "VZF/FP"
#>
#> $vz.pred$pptestcd_cdisc$route$intravascular
#> [1] "VZP"
#>
#>
#>
#> $vz.pred$pptest_cdisc
#> $vz.pred$pptest_cdisc$route
#> $vz.pred$pptest_cdisc$route$extravascular
#> [1] "Vz by F Pred"
#>
#> $vz.pred$pptest_cdisc$route$intravascular
#> [1] "Vz Pred"
#>
#>
#>
#>
#> $vz.int.inf.obs
#> $vz.int.inf.obs$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.int.inf.obs$values
#> [1] FALSE TRUE
#>
#> $vz.int.inf.obs$unit_type
#> [1] "volume"
#>
#> $vz.int.inf.obs$pretty_name
#> [1] "Vz (based on AUCint.inf.obs)"
#>
#> $vz.int.inf.obs$desc
#> [1] "Terminal volume of distribution using interval AUCint.inf.obs"
#>
#> $vz.int.inf.obs$sparse
#> [1] FALSE
#>
#> $vz.int.inf.obs$formalsmap
#> $vz.int.inf.obs$formalsmap$cl
#> [1] "cl.int.inf.obs"
#>
#>
#> $vz.int.inf.obs$depends
#> [1] "cl.int.inf.obs" "lambda.z"
#>
#> $vz.int.inf.obs$datatype
#> [1] "interval"
#>
#> $vz.int.inf.obs$pptestcd_cdisc
#> [1] "vz.int.inf.obs"
#>
#> $vz.int.inf.obs$pptest_cdisc
#> [1] "Terminal volume of distribution using interval AUCint.inf.obs"
#>
#>
#> $vz.int.inf.pred
#> $vz.int.inf.pred$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.int.inf.pred$values
#> [1] FALSE TRUE
#>
#> $vz.int.inf.pred$unit_type
#> [1] "volume"
#>
#> $vz.int.inf.pred$pretty_name
#> [1] "Vz (based on AUCint.inf.pred)"
#>
#> $vz.int.inf.pred$desc
#> [1] "Terminal volume of distribution using interval AUCint.inf.pred"
#>
#> $vz.int.inf.pred$sparse
#> [1] FALSE
#>
#> $vz.int.inf.pred$formalsmap
#> $vz.int.inf.pred$formalsmap$cl
#> [1] "cl.int.inf.pred"
#>
#>
#> $vz.int.inf.pred$depends
#> [1] "cl.int.inf.pred" "lambda.z"
#>
#> $vz.int.inf.pred$datatype
#> [1] "interval"
#>
#> $vz.int.inf.pred$pptestcd_cdisc
#> [1] "vz.int.inf.pred"
#>
#> $vz.int.inf.pred$pptest_cdisc
#> [1] "Terminal volume of distribution using interval AUCint.inf.pred"
#>
#>
#> $vz.iv.obs
#> $vz.iv.obs$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.iv.obs$values
#> [1] FALSE TRUE
#>
#> $vz.iv.obs$unit_type
#> [1] "volume"
#>
#> $vz.iv.obs$pretty_name
#> [1] "Vz (for IV dosing, based on AUCinf,obs)"
#>
#> $vz.iv.obs$desc
#> [1] "Terminal volume of distribution for IV dosing using observed AUCinf"
#>
#> $vz.iv.obs$sparse
#> [1] FALSE
#>
#> $vz.iv.obs$formalsmap
#> $vz.iv.obs$formalsmap$cl
#> [1] "cl.iv.obs"
#>
#>
#> $vz.iv.obs$depends
#> [1] "cl.iv.obs" "lambda.z"
#>
#> $vz.iv.obs$datatype
#> [1] "interval"
#>
#> $vz.iv.obs$pptestcd_cdisc
#> [1] "vz.iv.obs"
#>
#> $vz.iv.obs$pptest_cdisc
#> [1] "Terminal volume of distribution for IV dosing using observed AUCinf"
#>
#>
#> $vz.iv.pred
#> $vz.iv.pred$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.iv.pred$values
#> [1] FALSE TRUE
#>
#> $vz.iv.pred$unit_type
#> [1] "volume"
#>
#> $vz.iv.pred$pretty_name
#> [1] "Vz (for IV dosing, based on AUCinf,pred)"
#>
#> $vz.iv.pred$desc
#> [1] "Terminal volume of distribution for IV dosing using predicted AUCinf"
#>
#> $vz.iv.pred$sparse
#> [1] FALSE
#>
#> $vz.iv.pred$formalsmap
#> $vz.iv.pred$formalsmap$cl
#> [1] "cl.iv.pred"
#>
#>
#> $vz.iv.pred$depends
#> [1] "cl.iv.pred" "lambda.z"
#>
#> $vz.iv.pred$datatype
#> [1] "interval"
#>
#> $vz.iv.pred$pptestcd_cdisc
#> [1] "vz.iv.pred"
#>
#> $vz.iv.pred$pptest_cdisc
#> [1] "Terminal volume of distribution for IV dosing using predicted AUCinf"
#>
#>
#> $vz.sparse.last
#> $vz.sparse.last$FUN
#> [1] "pk.calc.vz"
#>
#> $vz.sparse.last$values
#> [1] FALSE TRUE
#>
#> $vz.sparse.last$unit_type
#> [1] "volume"
#>
#> $vz.sparse.last$pretty_name
#> [1] "Vz (for sparse data, based on AUClast)"
#>
#> $vz.sparse.last$desc
#> [1] "Terminal volume of distribution from sparse sampling"
#>
#> $vz.sparse.last$sparse
#> [1] TRUE
#>
#> $vz.sparse.last$formalsmap
#> $vz.sparse.last$formalsmap$cl
#> [1] "cl.sparse.last"
#>
#> $vz.sparse.last$formalsmap$lambda.z
#> [1] "kel.sparse.last"
#>
#>
#> $vz.sparse.last$depends
#> [1] "cl.sparse.last" "kel.sparse.last"
#>
#> $vz.sparse.last$datatype
#> [1] "interval"
#>
#> $vz.sparse.last$pptestcd_cdisc
#> [1] "vz.sparse.last"
#>
#> $vz.sparse.last$pptest_cdisc
#> [1] "Terminal volume of distribution from sparse sampling"
#>
#>
#> $vss.obs
#> $vss.obs$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.obs$values
#> [1] FALSE TRUE
#>
#> $vss.obs$unit_type
#> [1] "volume"
#>
#> $vss.obs$pretty_name
#> [1] "Vss (based on AUCinf,obs)"
#>
#> $vss.obs$desc
#> [1] "The steady-state volume of distribution using observed Clast"
#>
#> $vss.obs$sparse
#> [1] FALSE
#>
#> $vss.obs$formalsmap
#> $vss.obs$formalsmap$cl
#> [1] "cl.obs"
#>
#> $vss.obs$formalsmap$mrt
#> [1] "mrt.obs"
#>
#>
#> $vss.obs$depends
#> [1] "cl.obs" "mrt.obs"
#>
#> $vss.obs$datatype
#> [1] "interval"
#>
#> $vss.obs$pptestcd_cdisc
#> $vss.obs$pptestcd_cdisc$route
#> $vss.obs$pptestcd_cdisc$route$extravascular
#> [1] "VSSF/FO"
#>
#> $vss.obs$pptestcd_cdisc$route$intravascular
#> [1] "VSSO"
#>
#>
#>
#> $vss.obs$pptest_cdisc
#> $vss.obs$pptest_cdisc$route
#> $vss.obs$pptest_cdisc$route$extravascular
#> [1] "Vss by F Obs"
#>
#> $vss.obs$pptest_cdisc$route$intravascular
#> [1] "Vol Dist Steady State Obs"
#>
#>
#>
#>
#> $vss.pred
#> $vss.pred$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.pred$values
#> [1] FALSE TRUE
#>
#> $vss.pred$unit_type
#> [1] "volume"
#>
#> $vss.pred$pretty_name
#> [1] "Vss (based on AUCinf,pred)"
#>
#> $vss.pred$desc
#> [1] "The steady-state volume of distribution using predicted Clast"
#>
#> $vss.pred$sparse
#> [1] FALSE
#>
#> $vss.pred$formalsmap
#> $vss.pred$formalsmap$cl
#> [1] "cl.pred"
#>
#> $vss.pred$formalsmap$mrt
#> [1] "mrt.pred"
#>
#>
#> $vss.pred$depends
#> [1] "cl.pred" "mrt.pred"
#>
#> $vss.pred$datatype
#> [1] "interval"
#>
#> $vss.pred$pptestcd_cdisc
#> $vss.pred$pptestcd_cdisc$route
#> $vss.pred$pptestcd_cdisc$route$extravascular
#> [1] "VSSF/FP"
#>
#> $vss.pred$pptestcd_cdisc$route$intravascular
#> [1] "VSSP"
#>
#>
#>
#> $vss.pred$pptest_cdisc
#> $vss.pred$pptest_cdisc$route
#> $vss.pred$pptest_cdisc$route$extravascular
#> [1] "Vss by F Pred"
#>
#> $vss.pred$pptest_cdisc$route$intravascular
#> [1] "Vol Dist Steady State Pred"
#>
#>
#>
#>
#> $vss.iv.obs
#> $vss.iv.obs$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.iv.obs$values
#> [1] FALSE TRUE
#>
#> $vss.iv.obs$unit_type
#> [1] "volume"
#>
#> $vss.iv.obs$pretty_name
#> [1] "Vss (for IV dosing, based on AUCinf,obs)"
#>
#> $vss.iv.obs$desc
#> [1] "The steady-state volume of distribution with intravenous infusion using observed Clast"
#>
#> $vss.iv.obs$sparse
#> [1] FALSE
#>
#> $vss.iv.obs$formalsmap
#> $vss.iv.obs$formalsmap$cl
#> [1] "cl.obs"
#>
#> $vss.iv.obs$formalsmap$mrt
#> [1] "mrt.iv.obs"
#>
#>
#> $vss.iv.obs$depends
#> [1] "cl.obs" "mrt.iv.obs"
#>
#> $vss.iv.obs$datatype
#> [1] "interval"
#>
#> $vss.iv.obs$pptestcd_cdisc
#> [1] "VSSIVO"
#>
#> $vss.iv.obs$pptest_cdisc
#> [1] "Vss (for IV dosing, based on AUCinf,obs)"
#>
#>
#> $vss.iv.pred
#> $vss.iv.pred$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.iv.pred$values
#> [1] FALSE TRUE
#>
#> $vss.iv.pred$unit_type
#> [1] "volume"
#>
#> $vss.iv.pred$pretty_name
#> [1] "Vss (for IV dosing, based on AUCinf,pred)"
#>
#> $vss.iv.pred$desc
#> [1] "The steady-state volume of distribution with intravenous infusion using predicted Clast"
#>
#> $vss.iv.pred$sparse
#> [1] FALSE
#>
#> $vss.iv.pred$formalsmap
#> $vss.iv.pred$formalsmap$cl
#> [1] "cl.pred"
#>
#> $vss.iv.pred$formalsmap$mrt
#> [1] "mrt.iv.pred"
#>
#>
#> $vss.iv.pred$depends
#> [1] "cl.pred" "mrt.iv.pred"
#>
#> $vss.iv.pred$datatype
#> [1] "interval"
#>
#> $vss.iv.pred$pptestcd_cdisc
#> [1] "VSSIVP"
#>
#> $vss.iv.pred$pptest_cdisc
#> [1] "Vss (for IV dosing, based on AUCinf,pred)"
#>
#>
#> $vss.md.obs
#> $vss.md.obs$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.md.obs$values
#> [1] FALSE TRUE
#>
#> $vss.md.obs$unit_type
#> [1] "volume"
#>
#> $vss.md.obs$pretty_name
#> [1] "Vss (for multiple-dose, based on Clast,obs)"
#>
#> $vss.md.obs$desc
#> [1] "The steady-state volume of distribution for nonlinear multiple-dose data using observed Clast"
#>
#> $vss.md.obs$sparse
#> [1] FALSE
#>
#> $vss.md.obs$formalsmap
#> $vss.md.obs$formalsmap$cl
#> [1] "cl.last"
#>
#> $vss.md.obs$formalsmap$mrt
#> [1] "mrt.md.obs"
#>
#>
#> $vss.md.obs$depends
#> [1] "cl.last" "mrt.md.obs"
#>
#> $vss.md.obs$datatype
#> [1] "interval"
#>
#> $vss.md.obs$pptestcd_cdisc
#> [1] "VSSMDO"
#>
#> $vss.md.obs$pptest_cdisc
#> [1] "Vss (for multiple-dose, based on AUCinf,obs)"
#>
#>
#> $vss.md.pred
#> $vss.md.pred$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.md.pred$values
#> [1] FALSE TRUE
#>
#> $vss.md.pred$unit_type
#> [1] "volume"
#>
#> $vss.md.pred$pretty_name
#> [1] "Vss (for multiple-dose, based on Clast,pred)"
#>
#> $vss.md.pred$desc
#> [1] "The steady-state volume of distribution for nonlinear multiple-dose data using predicted Clast"
#>
#> $vss.md.pred$sparse
#> [1] FALSE
#>
#> $vss.md.pred$formalsmap
#> $vss.md.pred$formalsmap$cl
#> [1] "cl.last"
#>
#> $vss.md.pred$formalsmap$mrt
#> [1] "mrt.md.pred"
#>
#>
#> $vss.md.pred$depends
#> [1] "cl.last" "mrt.md.pred"
#>
#> $vss.md.pred$datatype
#> [1] "interval"
#>
#> $vss.md.pred$pptestcd_cdisc
#> [1] "VSSMDP"
#>
#> $vss.md.pred$pptest_cdisc
#> [1] "Vss (for multiple-dose, based on AUCinf,pred)"
#>
#>
#> $vss.int.inf.obs
#> $vss.int.inf.obs$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.int.inf.obs$values
#> [1] FALSE TRUE
#>
#> $vss.int.inf.obs$unit_type
#> [1] "volume"
#>
#> $vss.int.inf.obs$pretty_name
#> [1] "Vss (based on AUCint.inf.obs)"
#>
#> $vss.int.inf.obs$desc
#> [1] "Steady-state volume of distribution using interval AUCint.inf.obs"
#>
#> $vss.int.inf.obs$sparse
#> [1] FALSE
#>
#> $vss.int.inf.obs$formalsmap
#> $vss.int.inf.obs$formalsmap$cl
#> [1] "cl.int.inf.obs"
#>
#> $vss.int.inf.obs$formalsmap$mrt
#> [1] "mrt.int.inf.obs"
#>
#>
#> $vss.int.inf.obs$depends
#> [1] "cl.int.inf.obs" "mrt.int.inf.obs"
#>
#> $vss.int.inf.obs$datatype
#> [1] "interval"
#>
#> $vss.int.inf.obs$pptestcd_cdisc
#> [1] "vss.int.inf.obs"
#>
#> $vss.int.inf.obs$pptest_cdisc
#> [1] "Steady-state volume of distribution using interval AUCint.inf.obs"
#>
#>
#> $vss.int.inf.pred
#> $vss.int.inf.pred$FUN
#> [1] "pk.calc.vss"
#>
#> $vss.int.inf.pred$values
#> [1] FALSE TRUE
#>
#> $vss.int.inf.pred$unit_type
#> [1] "volume"
#>
#> $vss.int.inf.pred$pretty_name
#> [1] "Vss (based on AUCint.inf.pred)"
#>
#> $vss.int.inf.pred$desc
#> [1] "Steady-state volume of distribution using interval AUCint.inf.pred"
#>
#> $vss.int.inf.pred$sparse
#> [1] FALSE
#>
#> $vss.int.inf.pred$formalsmap
#> $vss.int.inf.pred$formalsmap$cl
#> [1] "cl.int.inf.pred"
#>
#> $vss.int.inf.pred$formalsmap$mrt
#> [1] "mrt.int.inf.pred"
#>
#>
#> $vss.int.inf.pred$depends
#> [1] "cl.int.inf.pred" "mrt.int.inf.pred"
#>
#> $vss.int.inf.pred$datatype
#> [1] "interval"
#>
#> $vss.int.inf.pred$pptestcd_cdisc
#> [1] "vss.int.inf.pred"
#>
#> $vss.int.inf.pred$pptest_cdisc
#> [1] "Steady-state volume of distribution using interval AUCint.inf.pred"
#>
#>
#> $cav.int.inf.obs
#> $cav.int.inf.obs$FUN
#> [1] "pk.calc.cav"
#>
#> $cav.int.inf.obs$values
#> [1] FALSE TRUE
#>
#> $cav.int.inf.obs$unit_type
#> [1] "conc"
#>
#> $cav.int.inf.obs$pretty_name
#> [1] "Cav"
#>
#> $cav.int.inf.obs$desc
#> [1] "The average concentration during an interval (calculated with AUCint.inf.obs)"
#>
#> $cav.int.inf.obs$sparse
#> [1] FALSE
#>
#> $cav.int.inf.obs$formalsmap
#> $cav.int.inf.obs$formalsmap$auc
#> [1] "aucint.inf.obs"
#>
#>
#> $cav.int.inf.obs$depends
#> [1] "aucint.inf.obs"
#>
#> $cav.int.inf.obs$datatype
#> [1] "interval"
#>
#> $cav.int.inf.obs$pptestcd_cdisc
#> [1] "CAVGINO"
#>
#> $cav.int.inf.obs$pptest_cdisc
#> [1] "Cavg Infinity Obs"
#>
#>
#> $cav.int.inf.pred
#> $cav.int.inf.pred$FUN
#> [1] "pk.calc.cav"
#>
#> $cav.int.inf.pred$values
#> [1] FALSE TRUE
#>
#> $cav.int.inf.pred$unit_type
#> [1] "conc"
#>
#> $cav.int.inf.pred$pretty_name
#> [1] "Cav"
#>
#> $cav.int.inf.pred$desc
#> [1] "The average concentration during an interval (calculated with AUCint.inf.pred)"
#>
#> $cav.int.inf.pred$sparse
#> [1] FALSE
#>
#> $cav.int.inf.pred$formalsmap
#> $cav.int.inf.pred$formalsmap$auc
#> [1] "aucint.inf.pred"
#>
#>
#> $cav.int.inf.pred$depends
#> [1] "aucint.inf.pred"
#>
#> $cav.int.inf.pred$datatype
#> [1] "interval"
#>
#> $cav.int.inf.pred$pptestcd_cdisc
#> [1] "CAVGINP"
#>
#> $cav.int.inf.pred$pptest_cdisc
#> [1] "Cavg Infinity Pred"
#>
#>
#> $thalf.eff.obs
#> $thalf.eff.obs$FUN
#> [1] "pk.calc.thalf.eff"
#>
#> $thalf.eff.obs$values
#> [1] FALSE TRUE
#>
#> $thalf.eff.obs$unit_type
#> [1] "time"
#>
#> $thalf.eff.obs$pretty_name
#> [1] "Effective half-life (based on MRT,obs)"
#>
#> $thalf.eff.obs$desc
#> [1] "The effective half-life (as determined from the MRTobs)"
#>
#> $thalf.eff.obs$sparse
#> [1] FALSE
#>
#> $thalf.eff.obs$formalsmap
#> $thalf.eff.obs$formalsmap$mrt
#> [1] "mrt.obs"
#>
#>
#> $thalf.eff.obs$depends
#> [1] "mrt.obs"
#>
#> $thalf.eff.obs$datatype
#> [1] "interval"
#>
#> $thalf.eff.obs$pptestcd_cdisc
#> [1] "EFFOHL"
#>
#> $thalf.eff.obs$pptest_cdisc
#> [1] "Effective Half-Life Obs"
#>
#>
#> $thalf.eff.pred
#> $thalf.eff.pred$FUN
#> [1] "pk.calc.thalf.eff"
#>
#> $thalf.eff.pred$values
#> [1] FALSE TRUE
#>
#> $thalf.eff.pred$unit_type
#> [1] "time"
#>
#> $thalf.eff.pred$pretty_name
#> [1] "Effective half-life (based on MRT,pred)"
#>
#> $thalf.eff.pred$desc
#> [1] "The effective half-life (as determined from the MRTpred)"
#>
#> $thalf.eff.pred$sparse
#> [1] FALSE
#>
#> $thalf.eff.pred$formalsmap
#> $thalf.eff.pred$formalsmap$mrt
#> [1] "mrt.pred"
#>
#>
#> $thalf.eff.pred$depends
#> [1] "mrt.pred"
#>
#> $thalf.eff.pred$datatype
#> [1] "interval"
#>
#> $thalf.eff.pred$pptestcd_cdisc
#> [1] "EFFPHL"
#>
#> $thalf.eff.pred$pptest_cdisc
#> [1] "Effective Half-Life Pred"
#>
#>
#> $thalf.eff.iv.obs
#> $thalf.eff.iv.obs$FUN
#> [1] "pk.calc.thalf.eff"
#>
#> $thalf.eff.iv.obs$values
#> [1] FALSE TRUE
#>
#> $thalf.eff.iv.obs$unit_type
#> [1] "time"
#>
#> $thalf.eff.iv.obs$pretty_name
#> [1] "Effective half-life (for IV dosing, based on MRT,obs)"
#>
#> $thalf.eff.iv.obs$desc
#> [1] "The effective half-life (as determined from the intravenous MRTobs)"
#>
#> $thalf.eff.iv.obs$sparse
#> [1] FALSE
#>
#> $thalf.eff.iv.obs$formalsmap
#> $thalf.eff.iv.obs$formalsmap$mrt
#> [1] "mrt.iv.obs"
#>
#>
#> $thalf.eff.iv.obs$depends
#> [1] "mrt.iv.obs"
#>
#> $thalf.eff.iv.obs$datatype
#> [1] "interval"
#>
#> $thalf.eff.iv.obs$pptestcd_cdisc
#> [1] "EFFIVOHL"
#>
#> $thalf.eff.iv.obs$pptest_cdisc
#> [1] "Effective Half-Life (for IV dosing, based on MRT Obs)"
#>
#>
#> $thalf.eff.iv.pred
#> $thalf.eff.iv.pred$FUN
#> [1] "pk.calc.thalf.eff"
#>
#> $thalf.eff.iv.pred$values
#> [1] FALSE TRUE
#>
#> $thalf.eff.iv.pred$unit_type
#> [1] "time"
#>
#> $thalf.eff.iv.pred$pretty_name
#> [1] "Effective half-life (for IV dosing, based on MRT,pred)"
#>
#> $thalf.eff.iv.pred$desc
#> [1] "The effective half-life (as determined from the intravenous MRTpred)"
#>
#> $thalf.eff.iv.pred$sparse
#> [1] FALSE
#>
#> $thalf.eff.iv.pred$formalsmap
#> $thalf.eff.iv.pred$formalsmap$mrt
#> [1] "mrt.iv.pred"
#>
#>
#> $thalf.eff.iv.pred$depends
#> [1] "mrt.iv.pred"
#>
#> $thalf.eff.iv.pred$datatype
#> [1] "interval"
#>
#> $thalf.eff.iv.pred$pptestcd_cdisc
#> [1] "EFFIVPHL"
#>
#> $thalf.eff.iv.pred$pptest_cdisc
#> [1] "Effective Half-Life (for IV dosing, based on MRT Pred)"
#>
#>
#> $kel.obs
#> $kel.obs$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.obs$values
#> [1] FALSE TRUE
#>
#> $kel.obs$unit_type
#> [1] "inverse_time"
#>
#> $kel.obs$pretty_name
#> [1] "Kel (based on AUCinf,obs)"
#>
#> $kel.obs$desc
#> [1] "Elimination rate (as calculated from the MRT with observed Clast)"
#>
#> $kel.obs$sparse
#> [1] FALSE
#>
#> $kel.obs$formalsmap
#> $kel.obs$formalsmap$mrt
#> [1] "mrt.obs"
#>
#>
#> $kel.obs$depends
#> [1] "mrt.obs"
#>
#> $kel.obs$datatype
#> [1] "interval"
#>
#> $kel.obs$pptestcd_cdisc
#> [1] "KELOS"
#>
#> $kel.obs$pptest_cdisc
#> [1] "Kel (based on AUCinf,obs)"
#>
#>
#> $kel.pred
#> $kel.pred$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.pred$values
#> [1] FALSE TRUE
#>
#> $kel.pred$unit_type
#> [1] "inverse_time"
#>
#> $kel.pred$pretty_name
#> [1] "Kel (based on AUCinf,pred)"
#>
#> $kel.pred$desc
#> [1] "Elimination rate (as calculated from the MRT with predicted Clast)"
#>
#> $kel.pred$sparse
#> [1] FALSE
#>
#> $kel.pred$formalsmap
#> $kel.pred$formalsmap$mrt
#> [1] "mrt.pred"
#>
#>
#> $kel.pred$depends
#> [1] "mrt.pred"
#>
#> $kel.pred$datatype
#> [1] "interval"
#>
#> $kel.pred$pptestcd_cdisc
#> [1] "KELP"
#>
#> $kel.pred$pptest_cdisc
#> [1] "Kel (based on AUCinf,pred)"
#>
#>
#> $kel.iv.obs
#> $kel.iv.obs$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.iv.obs$values
#> [1] FALSE TRUE
#>
#> $kel.iv.obs$unit_type
#> [1] "inverse_time"
#>
#> $kel.iv.obs$pretty_name
#> [1] "Kel (for IV dosing, based on AUCinf,obs)"
#>
#> $kel.iv.obs$desc
#> [1] "Elimination rate (as calculated from the intravenous MRTobs)"
#>
#> $kel.iv.obs$sparse
#> [1] FALSE
#>
#> $kel.iv.obs$formalsmap
#> $kel.iv.obs$formalsmap$mrt
#> [1] "mrt.iv.obs"
#>
#>
#> $kel.iv.obs$depends
#> [1] "mrt.iv.obs"
#>
#> $kel.iv.obs$datatype
#> [1] "interval"
#>
#> $kel.iv.obs$pptestcd_cdisc
#> [1] "KELIVOS"
#>
#> $kel.iv.obs$pptest_cdisc
#> [1] "Kel (for IV dosing, based on AUCinf,obs)"
#>
#>
#> $kel.iv.pred
#> $kel.iv.pred$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.iv.pred$values
#> [1] FALSE TRUE
#>
#> $kel.iv.pred$unit_type
#> [1] "inverse_time"
#>
#> $kel.iv.pred$pretty_name
#> [1] "Kel (for IV dosing, based on AUCinf,pred)"
#>
#> $kel.iv.pred$desc
#> [1] "Elimination rate (as calculated from the intravenous MRTpred)"
#>
#> $kel.iv.pred$sparse
#> [1] FALSE
#>
#> $kel.iv.pred$formalsmap
#> $kel.iv.pred$formalsmap$mrt
#> [1] "mrt.iv.pred"
#>
#>
#> $kel.iv.pred$depends
#> [1] "mrt.iv.pred"
#>
#> $kel.iv.pred$datatype
#> [1] "interval"
#>
#> $kel.iv.pred$pptestcd_cdisc
#> [1] "KELIVP"
#>
#> $kel.iv.pred$pptest_cdisc
#> [1] "Kel (for IV dosing, based on AUCinf,pred)"
#>
#>
#> $kel.int.inf.obs
#> $kel.int.inf.obs$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.int.inf.obs$values
#> [1] FALSE TRUE
#>
#> $kel.int.inf.obs$unit_type
#> [1] "inverse_time"
#>
#> $kel.int.inf.obs$pretty_name
#> [1] "Kel (based on AUCint.inf.obs)"
#>
#> $kel.int.inf.obs$desc
#> [1] "Elimination rate (as calculated from the MRTint.inf.obs)"
#>
#> $kel.int.inf.obs$sparse
#> [1] FALSE
#>
#> $kel.int.inf.obs$formalsmap
#> $kel.int.inf.obs$formalsmap$mrt
#> [1] "mrt.int.inf.obs"
#>
#>
#> $kel.int.inf.obs$depends
#> [1] "mrt.int.inf.obs"
#>
#> $kel.int.inf.obs$datatype
#> [1] "interval"
#>
#> $kel.int.inf.obs$pptestcd_cdisc
#> [1] "kel.int.inf.obs"
#>
#> $kel.int.inf.obs$pptest_cdisc
#> [1] "Elimination rate (as calculated from the MRTint.inf.obs)"
#>
#>
#> $kel.int.inf.pred
#> $kel.int.inf.pred$FUN
#> [1] "pk.calc.kel"
#>
#> $kel.int.inf.pred$values
#> [1] FALSE TRUE
#>
#> $kel.int.inf.pred$unit_type
#> [1] "inverse_time"
#>
#> $kel.int.inf.pred$pretty_name
#> [1] "Kel (based on AUCint.inf.pred)"
#>
#> $kel.int.inf.pred$desc
#> [1] "Elimination rate (as calculated from the MRTint.inf.pred)"
#>
#> $kel.int.inf.pred$sparse
#> [1] FALSE
#>
#> $kel.int.inf.pred$formalsmap
#> $kel.int.inf.pred$formalsmap$mrt
#> [1] "mrt.int.inf.pred"
#>
#>
#> $kel.int.inf.pred$depends
#> [1] "mrt.int.inf.pred"
#>
#> $kel.int.inf.pred$datatype
#> [1] "interval"
#>
#> $kel.int.inf.pred$pptestcd_cdisc
#> [1] "kel.int.inf.pred"
#>
#> $kel.int.inf.pred$pptest_cdisc
#> [1] "Elimination rate (as calculated from the MRTint.inf.pred)"
#>
#>
#> $auclast.dn
#> $auclast.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $auclast.dn$values
#> [1] FALSE TRUE
#>
#> $auclast.dn$unit_type
#> [1] "auc_dosenorm"
#>
#> $auclast.dn$pretty_name
#> [1] "AUClast (dose-normalized)"
#>
#> $auclast.dn$desc
#> [1] "Dose normalized auclast"
#>
#> $auclast.dn$sparse
#> [1] FALSE
#>
#> $auclast.dn$formalsmap
#> $auclast.dn$formalsmap$parameter
#> [1] "auclast"
#>
#>
#> $auclast.dn$depends
#> [1] "auclast"
#>
#> $auclast.dn$datatype
#> [1] "interval"
#>
#> $auclast.dn$pptestcd_cdisc
#> [1] "AUCLSTD"
#>
#> $auclast.dn$pptest_cdisc
#> [1] "AUC to Last Nonzero Conc by Dose"
#>
#>
#> $aucall.dn
#> $aucall.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $aucall.dn$values
#> [1] FALSE TRUE
#>
#> $aucall.dn$unit_type
#> [1] "auc_dosenorm"
#>
#> $aucall.dn$pretty_name
#> [1] "AUCall (dose-normalized)"
#>
#> $aucall.dn$desc
#> [1] "Dose normalized aucall"
#>
#> $aucall.dn$sparse
#> [1] FALSE
#>
#> $aucall.dn$formalsmap
#> $aucall.dn$formalsmap$parameter
#> [1] "aucall"
#>
#>
#> $aucall.dn$depends
#> [1] "aucall"
#>
#> $aucall.dn$datatype
#> [1] "interval"
#>
#> $aucall.dn$pptestcd_cdisc
#> [1] "AUCALLD"
#>
#> $aucall.dn$pptest_cdisc
#> [1] "AUC All by Dose"
#>
#>
#> $aucinf.obs.dn
#> $aucinf.obs.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $aucinf.obs.dn$values
#> [1] FALSE TRUE
#>
#> $aucinf.obs.dn$unit_type
#> [1] "auc_dosenorm"
#>
#> $aucinf.obs.dn$pretty_name
#> [1] "AUCinf,obs (dose-normalized)"
#>
#> $aucinf.obs.dn$desc
#> [1] "Dose normalized aucinf.obs"
#>
#> $aucinf.obs.dn$sparse
#> [1] FALSE
#>
#> $aucinf.obs.dn$formalsmap
#> $aucinf.obs.dn$formalsmap$parameter
#> [1] "aucinf.obs"
#>
#>
#> $aucinf.obs.dn$depends
#> [1] "aucinf.obs"
#>
#> $aucinf.obs.dn$datatype
#> [1] "interval"
#>
#> $aucinf.obs.dn$pptestcd_cdisc
#> [1] "AUCIFOD"
#>
#> $aucinf.obs.dn$pptest_cdisc
#> [1] "AUC Infinity Obs by Dose"
#>
#>
#> $aucinf.pred.dn
#> $aucinf.pred.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $aucinf.pred.dn$values
#> [1] FALSE TRUE
#>
#> $aucinf.pred.dn$unit_type
#> [1] "auc_dosenorm"
#>
#> $aucinf.pred.dn$pretty_name
#> [1] "AUCinf,pred (dose-normalized)"
#>
#> $aucinf.pred.dn$desc
#> [1] "Dose normalized aucinf.pred"
#>
#> $aucinf.pred.dn$sparse
#> [1] FALSE
#>
#> $aucinf.pred.dn$formalsmap
#> $aucinf.pred.dn$formalsmap$parameter
#> [1] "aucinf.pred"
#>
#>
#> $aucinf.pred.dn$depends
#> [1] "aucinf.pred"
#>
#> $aucinf.pred.dn$datatype
#> [1] "interval"
#>
#> $aucinf.pred.dn$pptestcd_cdisc
#> [1] "AUCIFPD"
#>
#> $aucinf.pred.dn$pptest_cdisc
#> [1] "AUC Infinity Pred by Dose"
#>
#>
#> $aumclast.dn
#> $aumclast.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $aumclast.dn$values
#> [1] FALSE TRUE
#>
#> $aumclast.dn$unit_type
#> [1] "aumc_dosenorm"
#>
#> $aumclast.dn$pretty_name
#> [1] "AUMC,last (dose-normalized)"
#>
#> $aumclast.dn$desc
#> [1] "Dose normalized aumclast"
#>
#> $aumclast.dn$sparse
#> [1] FALSE
#>
#> $aumclast.dn$formalsmap
#> $aumclast.dn$formalsmap$parameter
#> [1] "aumclast"
#>
#>
#> $aumclast.dn$depends
#> [1] "aumclast"
#>
#> $aumclast.dn$datatype
#> [1] "interval"
#>
#> $aumclast.dn$pptestcd_cdisc
#> [1] "AUMCLSTD"
#>
#> $aumclast.dn$pptest_cdisc
#> [1] "AUMC to Last Nonzero Conc by Dose"
#>
#>
#> $aumcall.dn
#> $aumcall.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $aumcall.dn$values
#> [1] FALSE TRUE
#>
#> $aumcall.dn$unit_type
#> [1] "aumc_dosenorm"
#>
#> $aumcall.dn$pretty_name
#> [1] "AUMC,all (dose-normalized)"
#>
#> $aumcall.dn$desc
#> [1] "Dose normalized aumcall"
#>
#> $aumcall.dn$sparse
#> [1] FALSE
#>
#> $aumcall.dn$formalsmap
#> $aumcall.dn$formalsmap$parameter
#> [1] "aumcall"
#>
#>
#> $aumcall.dn$depends
#> [1] "aumcall"
#>
#> $aumcall.dn$datatype
#> [1] "interval"
#>
#> $aumcall.dn$pptestcd_cdisc
#> [1] "AUMCALLD"
#>
#> $aumcall.dn$pptest_cdisc
#> [1] "AUMC All by Dose"
#>
#>
#> $aumcinf.obs.dn
#> $aumcinf.obs.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $aumcinf.obs.dn$values
#> [1] FALSE TRUE
#>
#> $aumcinf.obs.dn$unit_type
#> [1] "aumc_dosenorm"
#>
#> $aumcinf.obs.dn$pretty_name
#> [1] "AUMC,inf,obs (dose-normalized)"
#>
#> $aumcinf.obs.dn$desc
#> [1] "Dose normalized aumcinf.obs"
#>
#> $aumcinf.obs.dn$sparse
#> [1] FALSE
#>
#> $aumcinf.obs.dn$formalsmap
#> $aumcinf.obs.dn$formalsmap$parameter
#> [1] "aumcinf.obs"
#>
#>
#> $aumcinf.obs.dn$depends
#> [1] "aumcinf.obs"
#>
#> $aumcinf.obs.dn$datatype
#> [1] "interval"
#>
#> $aumcinf.obs.dn$pptestcd_cdisc
#> [1] "AUMCIFOD"
#>
#> $aumcinf.obs.dn$pptest_cdisc
#> [1] "AUMC Infinity Obs by Dose"
#>
#>
#> $aumcinf.pred.dn
#> $aumcinf.pred.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $aumcinf.pred.dn$values
#> [1] FALSE TRUE
#>
#> $aumcinf.pred.dn$unit_type
#> [1] "aumc_dosenorm"
#>
#> $aumcinf.pred.dn$pretty_name
#> [1] "AUMC,inf,pred (dose-normalized)"
#>
#> $aumcinf.pred.dn$desc
#> [1] "Dose normalized aumcinf.pred"
#>
#> $aumcinf.pred.dn$sparse
#> [1] FALSE
#>
#> $aumcinf.pred.dn$formalsmap
#> $aumcinf.pred.dn$formalsmap$parameter
#> [1] "aumcinf.pred"
#>
#>
#> $aumcinf.pred.dn$depends
#> [1] "aumcinf.pred"
#>
#> $aumcinf.pred.dn$datatype
#> [1] "interval"
#>
#> $aumcinf.pred.dn$pptestcd_cdisc
#> [1] "AUMCIFPD"
#>
#> $aumcinf.pred.dn$pptest_cdisc
#> [1] "AUMC Infinity Pred by Dose"
#>
#>
#> $cmax.dn
#> $cmax.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $cmax.dn$values
#> [1] FALSE TRUE
#>
#> $cmax.dn$unit_type
#> [1] "conc_dosenorm"
#>
#> $cmax.dn$pretty_name
#> [1] "Cmax (dose-normalized)"
#>
#> $cmax.dn$desc
#> [1] "Dose normalized cmax"
#>
#> $cmax.dn$sparse
#> [1] FALSE
#>
#> $cmax.dn$formalsmap
#> $cmax.dn$formalsmap$parameter
#> [1] "cmax"
#>
#>
#> $cmax.dn$depends
#> [1] "cmax"
#>
#> $cmax.dn$datatype
#> [1] "interval"
#>
#> $cmax.dn$pptestcd_cdisc
#> [1] "CMAXD"
#>
#> $cmax.dn$pptest_cdisc
#> [1] "Max Conc by Dose"
#>
#>
#> $cmin.dn
#> $cmin.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $cmin.dn$values
#> [1] FALSE TRUE
#>
#> $cmin.dn$unit_type
#> [1] "conc_dosenorm"
#>
#> $cmin.dn$pretty_name
#> [1] "Cmin (dose-normalized)"
#>
#> $cmin.dn$desc
#> [1] "Dose normalized cmin"
#>
#> $cmin.dn$sparse
#> [1] FALSE
#>
#> $cmin.dn$formalsmap
#> $cmin.dn$formalsmap$parameter
#> [1] "cmin"
#>
#>
#> $cmin.dn$depends
#> [1] "cmin"
#>
#> $cmin.dn$datatype
#> [1] "interval"
#>
#> $cmin.dn$pptestcd_cdisc
#> [1] "CMIND"
#>
#> $cmin.dn$pptest_cdisc
#> [1] "Min Conc by Dose"
#>
#>
#> $clast.obs.dn
#> $clast.obs.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $clast.obs.dn$values
#> [1] FALSE TRUE
#>
#> $clast.obs.dn$unit_type
#> [1] "conc_dosenorm"
#>
#> $clast.obs.dn$pretty_name
#> [1] "Clast (dose-normalized)"
#>
#> $clast.obs.dn$desc
#> [1] "Dose normalized clast.obs"
#>
#> $clast.obs.dn$sparse
#> [1] FALSE
#>
#> $clast.obs.dn$formalsmap
#> $clast.obs.dn$formalsmap$parameter
#> [1] "clast.obs"
#>
#>
#> $clast.obs.dn$depends
#> [1] "clast.obs"
#>
#> $clast.obs.dn$datatype
#> [1] "interval"
#>
#> $clast.obs.dn$pptestcd_cdisc
#> [1] "CLSTD"
#>
#> $clast.obs.dn$pptest_cdisc
#> [1] "Last Nonzero Conc by Dose"
#>
#>
#> $clast.pred.dn
#> $clast.pred.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $clast.pred.dn$values
#> [1] FALSE TRUE
#>
#> $clast.pred.dn$unit_type
#> [1] "conc_dosenorm"
#>
#> $clast.pred.dn$pretty_name
#> [1] "Clast,pred (dose-normalized)"
#>
#> $clast.pred.dn$desc
#> [1] "Dose normalized clast.pred"
#>
#> $clast.pred.dn$sparse
#> [1] FALSE
#>
#> $clast.pred.dn$formalsmap
#> $clast.pred.dn$formalsmap$parameter
#> [1] "clast.pred"
#>
#>
#> $clast.pred.dn$depends
#> [1] "clast.pred"
#>
#> $clast.pred.dn$datatype
#> [1] "interval"
#>
#> $clast.pred.dn$pptestcd_cdisc
#> [1] "CLSTPD"
#>
#> $clast.pred.dn$pptest_cdisc
#> [1] "Clast pred by Dose"
#>
#>
#> $cav.dn
#> $cav.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $cav.dn$values
#> [1] FALSE TRUE
#>
#> $cav.dn$unit_type
#> [1] "conc_dosenorm"
#>
#> $cav.dn$pretty_name
#> [1] "Cav (dose-normalized)"
#>
#> $cav.dn$desc
#> [1] "Dose normalized cav"
#>
#> $cav.dn$sparse
#> [1] FALSE
#>
#> $cav.dn$formalsmap
#> $cav.dn$formalsmap$parameter
#> [1] "cav"
#>
#>
#> $cav.dn$depends
#> [1] "cav"
#>
#> $cav.dn$datatype
#> [1] "interval"
#>
#> $cav.dn$pptestcd_cdisc
#> [1] "CAVGD"
#>
#> $cav.dn$pptest_cdisc
#> [1] "Average Conc by Dose"
#>
#>
#> $ctrough.dn
#> $ctrough.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $ctrough.dn$values
#> [1] FALSE TRUE
#>
#> $ctrough.dn$unit_type
#> [1] "conc_dosenorm"
#>
#> $ctrough.dn$pretty_name
#> [1] "Ctrough (dose-normalized)"
#>
#> $ctrough.dn$desc
#> [1] "Dose normalized ctrough"
#>
#> $ctrough.dn$sparse
#> [1] FALSE
#>
#> $ctrough.dn$formalsmap
#> $ctrough.dn$formalsmap$parameter
#> [1] "ctrough"
#>
#>
#> $ctrough.dn$depends
#> [1] "ctrough"
#>
#> $ctrough.dn$datatype
#> [1] "interval"
#>
#> $ctrough.dn$pptestcd_cdisc
#> [1] "CTROUGHD"
#>
#> $ctrough.dn$pptest_cdisc
#> [1] "Conc Trough by Dose"
#>
#>
#> $clr.last.dn
#> $clr.last.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $clr.last.dn$values
#> [1] FALSE TRUE
#>
#> $clr.last.dn$unit_type
#> [1] "renal_clearance_dosenorm"
#>
#> $clr.last.dn$pretty_name
#> [1] "Renal clearance (from AUClast) (dose-normalized)"
#>
#> $clr.last.dn$desc
#> [1] "Dose normalized clr.last"
#>
#> $clr.last.dn$sparse
#> [1] FALSE
#>
#> $clr.last.dn$formalsmap
#> $clr.last.dn$formalsmap$parameter
#> [1] "clr.last"
#>
#>
#> $clr.last.dn$depends
#> [1] "clr.last"
#>
#> $clr.last.dn$datatype
#> [1] "interval"
#>
#> $clr.last.dn$pptestcd_cdisc
#> [1] "RENALCLD"
#>
#> $clr.last.dn$pptest_cdisc
#> [1] "Renal CL by Dose"
#>
#>
#> $clr.obs.dn
#> $clr.obs.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $clr.obs.dn$values
#> [1] FALSE TRUE
#>
#> $clr.obs.dn$unit_type
#> [1] "renal_clearance_dosenorm"
#>
#> $clr.obs.dn$pretty_name
#> [1] "Renal clearance (from AUCinf,obs) (dose-normalized)"
#>
#> $clr.obs.dn$desc
#> [1] "Dose normalized clr.obs"
#>
#> $clr.obs.dn$sparse
#> [1] FALSE
#>
#> $clr.obs.dn$formalsmap
#> $clr.obs.dn$formalsmap$parameter
#> [1] "clr.obs"
#>
#>
#> $clr.obs.dn$depends
#> [1] "clr.obs"
#>
#> $clr.obs.dn$datatype
#> [1] "interval"
#>
#> $clr.obs.dn$pptestcd_cdisc
#> [1] "RENALCLD"
#>
#> $clr.obs.dn$pptest_cdisc
#> [1] "Renal CL by Dose"
#>
#>
#> $clr.pred.dn
#> $clr.pred.dn$FUN
#> [1] "pk.calc.dn"
#>
#> $clr.pred.dn$values
#> [1] FALSE TRUE
#>
#> $clr.pred.dn$unit_type
#> [1] "renal_clearance_dosenorm"
#>
#> $clr.pred.dn$pretty_name
#> [1] "Renal clearance (from AUCinf,pred) (dose-normalized)"
#>
#> $clr.pred.dn$desc
#> [1] "Dose normalized clr.pred"
#>
#> $clr.pred.dn$sparse
#> [1] FALSE
#>
#> $clr.pred.dn$formalsmap
#> $clr.pred.dn$formalsmap$parameter
#> [1] "clr.pred"
#>
#>
#> $clr.pred.dn$depends
#> [1] "clr.pred"
#>
#> $clr.pred.dn$datatype
#> [1] "interval"
#>
#> $clr.pred.dn$pptestcd_cdisc
#> [1] "RENALCLD"
#>
#> $clr.pred.dn$pptest_cdisc
#> [1] "Renal CL by Dose"
#>
#>