Skip to contents

Get the columns that can be used in an interval specification

Usage

get.interval.cols()

Value

A list with named elements for each parameter. Each list element contains the parameter definition.

See also

check.interval.specification() and the vignette "Selection of Calculation Intervals"

Other Interval specifications: add.interval.col(), check.interval.specification(), choose.auc.intervals(), get.parameter.deps()

Examples

get.interval.cols()
#> $start
#> $start$FUN
#> [1] NA
#> 
#> $start$values
#> function (x, ...)  .Primitive("as.double")
#> 
#> $start$unit_type
#> [1] "time"
#> 
#> $start$pretty_name
#> [1] "Interval Start"
#> 
#> $start$desc
#> [1] "Starting time of the interval"
#> 
#> $start$sparse
#> [1] FALSE
#> 
#> $start$formalsmap
#> list()
#> 
#> $start$depends
#> NULL
#> 
#> $start$datatype
#> [1] "interval"
#> 
#> $start$pptestcd_cdisc
#> [1] "start"
#> 
#> $start$pptest_cdisc
#> [1] "Starting time of the interval"
#> 
#> 
#> $end
#> $end$FUN
#> [1] NA
#> 
#> $end$values
#> function (x, ...)  .Primitive("as.double")
#> 
#> $end$unit_type
#> [1] "time"
#> 
#> $end$pretty_name
#> [1] "Interval End"
#> 
#> $end$desc
#> [1] "Ending time of the interval (potentially infinity)"
#> 
#> $end$sparse
#> [1] FALSE
#> 
#> $end$formalsmap
#> list()
#> 
#> $end$depends
#> NULL
#> 
#> $end$datatype
#> [1] "interval"
#> 
#> $end$pptestcd_cdisc
#> [1] "end"
#> 
#> $end$pptest_cdisc
#> [1] "Ending time of the interval (potentially infinity)"
#> 
#> 
#> $auclast
#> $auclast$FUN
#> [1] "pk.calc.auc.last"
#> 
#> $auclast$values
#> [1] FALSE  TRUE
#> 
#> $auclast$unit_type
#> [1] "auc"
#> 
#> $auclast$pretty_name
#> [1] "AUClast"
#> 
#> $auclast$desc
#> [1] "The area under the concentration time curve from the beginning of the interval to the last concentration above the limit of quantification"
#> 
#> $auclast$sparse
#> [1] FALSE
#> 
#> $auclast$formalsmap
#> list()
#> 
#> $auclast$depends
#> NULL
#> 
#> $auclast$datatype
#> [1] "interval"
#> 
#> $auclast$pptestcd_cdisc
#> [1] "AUCLST"
#> 
#> $auclast$pptest_cdisc
#> [1] "AUC to Last Nonzero Conc"
#> 
#> 
#> $aucall
#> $aucall$FUN
#> [1] "pk.calc.auc.all"
#> 
#> $aucall$values
#> [1] FALSE  TRUE
#> 
#> $aucall$unit_type
#> [1] "auc"
#> 
#> $aucall$pretty_name
#> [1] "AUCall"
#> 
#> $aucall$desc
#> [1] "The area under the concentration time curve from the beginning of the interval to the last concentration above the limit of quantification plus the triangle from that last concentration to 0 at the first concentration below the limit of quantification"
#> 
#> $aucall$sparse
#> [1] FALSE
#> 
#> $aucall$formalsmap
#> list()
#> 
#> $aucall$depends
#> NULL
#> 
#> $aucall$datatype
#> [1] "interval"
#> 
#> $aucall$pptestcd_cdisc
#> [1] "AUCALL"
#> 
#> $aucall$pptest_cdisc
#> [1] "AUC All"
#> 
#> 
#> $aumclast
#> $aumclast$FUN
#> [1] "pk.calc.aumc.last"
#> 
#> $aumclast$values
#> [1] FALSE  TRUE
#> 
#> $aumclast$unit_type
#> [1] "aumc"
#> 
#> $aumclast$pretty_name
#> [1] "AUMC,last"
#> 
#> $aumclast$desc
#> [1] "The area under the concentration time moment curve from the beginning of the interval to the last concentration above the limit of quantification"
#> 
#> $aumclast$sparse
#> [1] FALSE
#> 
#> $aumclast$formalsmap
#> list()
#> 
#> $aumclast$depends
#> NULL
#> 
#> $aumclast$datatype
#> [1] "interval"
#> 
#> $aumclast$pptestcd_cdisc
#> [1] "AUMCLST"
#> 
#> $aumclast$pptest_cdisc
#> [1] "AUMC to Last Nonzero Conc"
#> 
#> 
#> $aumcall
#> $aumcall$FUN
#> [1] "pk.calc.aumc.all"
#> 
#> $aumcall$values
#> [1] FALSE  TRUE
#> 
#> $aumcall$unit_type
#> [1] "aumc"
#> 
#> $aumcall$pretty_name
#> [1] "AUMC,all"
#> 
#> $aumcall$desc
#> [1] "The area under the concentration time moment curve from the beginning of the interval to the last concentration above the limit of quantification plus the moment of the triangle from that last concentration to 0 at the first concentration below the limit of quantification"
#> 
#> $aumcall$sparse
#> [1] FALSE
#> 
#> $aumcall$formalsmap
#> list()
#> 
#> $aumcall$depends
#> NULL
#> 
#> $aumcall$datatype
#> [1] "interval"
#> 
#> $aumcall$pptestcd_cdisc
#> [1] "AUMCALL"
#> 
#> $aumcall$pptest_cdisc
#> [1] "AUMC All"
#> 
#> 
#> $aucint.last
#> $aucint.last$FUN
#> [1] "pk.calc.aucint.last"
#> 
#> $aucint.last$values
#> [1] FALSE  TRUE
#> 
#> $aucint.last$unit_type
#> [1] "auc"
#> 
#> $aucint.last$pretty_name
#> [1] "AUCint (based on AUClast extrapolation)"
#> 
#> $aucint.last$desc
#> [1] "The area under the concentration time curve in the interval extrapolating from Tlast to infinity with zeros (matching AUClast)"
#> 
#> $aucint.last$sparse
#> [1] FALSE
#> 
#> $aucint.last$formalsmap
#> $aucint.last$formalsmap$conc
#> [1] "conc.group"
#> 
#> $aucint.last$formalsmap$time
#> [1] "time.group"
#> 
#> $aucint.last$formalsmap$time.dose
#> NULL
#> 
#> 
#> $aucint.last$depends
#> NULL
#> 
#> $aucint.last$datatype
#> [1] "interval"
#> 
#> $aucint.last$pptestcd_cdisc
#> [1] "AUCINT"
#> 
#> $aucint.last$pptest_cdisc
#> [1] "AUC from T1 to T2"
#> 
#> 
#> $aucint.last.dose
#> $aucint.last.dose$FUN
#> [1] "pk.calc.aucint.last"
#> 
#> $aucint.last.dose$values
#> [1] FALSE  TRUE
#> 
#> $aucint.last.dose$unit_type
#> [1] "auc"
#> 
#> $aucint.last.dose$pretty_name
#> [1] "AUCint (based on AUClast extrapolation, dose-aware)"
#> 
#> $aucint.last.dose$desc
#> [1] "The area under the concentration time curve in the interval extrapolating from Tlast to infinity with zeros (matching AUClast) with dose-aware interpolation/extrapolation of concentrations"
#> 
#> $aucint.last.dose$sparse
#> [1] FALSE
#> 
#> $aucint.last.dose$formalsmap
#> $aucint.last.dose$formalsmap$conc
#> [1] "conc.group"
#> 
#> $aucint.last.dose$formalsmap$time
#> [1] "time.group"
#> 
#> $aucint.last.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#> 
#> 
#> $aucint.last.dose$depends
#> NULL
#> 
#> $aucint.last.dose$datatype
#> [1] "interval"
#> 
#> $aucint.last.dose$pptestcd_cdisc
#> [1] "AUCINTD"
#> 
#> $aucint.last.dose$pptest_cdisc
#> [1] "AUC from T1 to T2 Normalized by Dose"
#> 
#> 
#> $aucint.all
#> $aucint.all$FUN
#> [1] "pk.calc.aucint.all"
#> 
#> $aucint.all$values
#> [1] FALSE  TRUE
#> 
#> $aucint.all$unit_type
#> [1] "auc"
#> 
#> $aucint.all$pretty_name
#> [1] "AUCint (based on AUCall extrapolation)"
#> 
#> $aucint.all$desc
#> [1] "The area under the concentration time curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUCall)"
#> 
#> $aucint.all$sparse
#> [1] FALSE
#> 
#> $aucint.all$formalsmap
#> $aucint.all$formalsmap$conc
#> [1] "conc.group"
#> 
#> $aucint.all$formalsmap$time
#> [1] "time.group"
#> 
#> $aucint.all$formalsmap$time.dose
#> NULL
#> 
#> 
#> $aucint.all$depends
#> NULL
#> 
#> $aucint.all$datatype
#> [1] "interval"
#> 
#> $aucint.all$pptestcd_cdisc
#> [1] "AUCINTA"
#> 
#> $aucint.all$pptest_cdisc
#> [1] "AUCint (based on AUCall extrapolation)"
#> 
#> 
#> $aucint.all.dose
#> $aucint.all.dose$FUN
#> [1] "pk.calc.aucint.all"
#> 
#> $aucint.all.dose$values
#> [1] FALSE  TRUE
#> 
#> $aucint.all.dose$unit_type
#> [1] "auc"
#> 
#> $aucint.all.dose$pretty_name
#> [1] "AUCint (based on AUCall extrapolation, dose-aware)"
#> 
#> $aucint.all.dose$desc
#> [1] "The area under the concentration time curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUCall) with dose-aware interpolation/extrapolation of concentrations"
#> 
#> $aucint.all.dose$sparse
#> [1] FALSE
#> 
#> $aucint.all.dose$formalsmap
#> $aucint.all.dose$formalsmap$conc
#> [1] "conc.group"
#> 
#> $aucint.all.dose$formalsmap$time
#> [1] "time.group"
#> 
#> $aucint.all.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#> 
#> 
#> $aucint.all.dose$depends
#> NULL
#> 
#> $aucint.all.dose$datatype
#> [1] "interval"
#> 
#> $aucint.all.dose$pptestcd_cdisc
#> [1] "AUCINTAD"
#> 
#> $aucint.all.dose$pptest_cdisc
#> [1] "AUCint (based on AUCall extrapolation, dose-aware)"
#> 
#> 
#> $aumcint.last
#> $aumcint.last$FUN
#> [1] "pk.calc.aumcint.last"
#> 
#> $aumcint.last$values
#> [1] FALSE  TRUE
#> 
#> $aumcint.last$unit_type
#> [1] "aumc"
#> 
#> $aumcint.last$pretty_name
#> [1] "AUMCint (based on AUMClast extrapolation)"
#> 
#> $aumcint.last$desc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with zeros (matching AUMClast)"
#> 
#> $aumcint.last$sparse
#> [1] FALSE
#> 
#> $aumcint.last$formalsmap
#> $aumcint.last$formalsmap$conc
#> [1] "conc.group"
#> 
#> $aumcint.last$formalsmap$time
#> [1] "time.group"
#> 
#> $aumcint.last$formalsmap$time.dose
#> NULL
#> 
#> 
#> $aumcint.last$depends
#> NULL
#> 
#> $aumcint.last$datatype
#> [1] "interval"
#> 
#> $aumcint.last$pptestcd_cdisc
#> [1] "aumcint.last"
#> 
#> $aumcint.last$pptest_cdisc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with zeros (matching AUMClast)"
#> 
#> 
#> $aumcint.last.dose
#> $aumcint.last.dose$FUN
#> [1] "pk.calc.aumcint.last"
#> 
#> $aumcint.last.dose$values
#> [1] FALSE  TRUE
#> 
#> $aumcint.last.dose$unit_type
#> [1] "aumc"
#> 
#> $aumcint.last.dose$pretty_name
#> [1] "AUMCint (based on AUMClast extrapolation, dose-aware)"
#> 
#> $aumcint.last.dose$desc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with zeros (matching AUMClast) with dose-aware interpolation/extrapolation of concentrations"
#> 
#> $aumcint.last.dose$sparse
#> [1] FALSE
#> 
#> $aumcint.last.dose$formalsmap
#> $aumcint.last.dose$formalsmap$conc
#> [1] "conc.group"
#> 
#> $aumcint.last.dose$formalsmap$time
#> [1] "time.group"
#> 
#> $aumcint.last.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#> 
#> 
#> $aumcint.last.dose$depends
#> NULL
#> 
#> $aumcint.last.dose$datatype
#> [1] "interval"
#> 
#> $aumcint.last.dose$pptestcd_cdisc
#> [1] "aumcint.last.dose"
#> 
#> $aumcint.last.dose$pptest_cdisc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with zeros (matching AUMClast) with dose-aware interpolation/extrapolation of concentrations"
#> 
#> 
#> $aumcint.all
#> $aumcint.all$FUN
#> [1] "pk.calc.aumcint.all"
#> 
#> $aumcint.all$values
#> [1] FALSE  TRUE
#> 
#> $aumcint.all$unit_type
#> [1] "aumc"
#> 
#> $aumcint.all$pretty_name
#> [1] "AUMCint (based on AUMCall extrapolation)"
#> 
#> $aumcint.all$desc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUMCall)"
#> 
#> $aumcint.all$sparse
#> [1] FALSE
#> 
#> $aumcint.all$formalsmap
#> $aumcint.all$formalsmap$conc
#> [1] "conc.group"
#> 
#> $aumcint.all$formalsmap$time
#> [1] "time.group"
#> 
#> $aumcint.all$formalsmap$time.dose
#> NULL
#> 
#> 
#> $aumcint.all$depends
#> NULL
#> 
#> $aumcint.all$datatype
#> [1] "interval"
#> 
#> $aumcint.all$pptestcd_cdisc
#> [1] "aumcint.all"
#> 
#> $aumcint.all$pptest_cdisc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUMCall)"
#> 
#> 
#> $aumcint.all.dose
#> $aumcint.all.dose$FUN
#> [1] "pk.calc.aumcint.all"
#> 
#> $aumcint.all.dose$values
#> [1] FALSE  TRUE
#> 
#> $aumcint.all.dose$unit_type
#> [1] "aumc"
#> 
#> $aumcint.all.dose$pretty_name
#> [1] "AUMCint (based on AUMCall extrapolation, dose-aware)"
#> 
#> $aumcint.all.dose$desc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUMCall) with dose-aware interpolation/extrapolation of concentrations"
#> 
#> $aumcint.all.dose$sparse
#> [1] FALSE
#> 
#> $aumcint.all.dose$formalsmap
#> $aumcint.all.dose$formalsmap$conc
#> [1] "conc.group"
#> 
#> $aumcint.all.dose$formalsmap$time
#> [1] "time.group"
#> 
#> $aumcint.all.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#> 
#> 
#> $aumcint.all.dose$depends
#> NULL
#> 
#> $aumcint.all.dose$datatype
#> [1] "interval"
#> 
#> $aumcint.all.dose$pptestcd_cdisc
#> [1] "aumcint.all.dose"
#> 
#> $aumcint.all.dose$pptest_cdisc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUMCall) with dose-aware interpolation/extrapolation of concentrations"
#> 
#> 
#> $c0
#> $c0$FUN
#> [1] "pk.calc.c0"
#> 
#> $c0$values
#> [1] FALSE  TRUE
#> 
#> $c0$unit_type
#> [1] "conc"
#> 
#> $c0$pretty_name
#> [1] "C0"
#> 
#> $c0$desc
#> [1] "Initial concentration after an IV bolus"
#> 
#> $c0$sparse
#> [1] FALSE
#> 
#> $c0$formalsmap
#> list()
#> 
#> $c0$depends
#> NULL
#> 
#> $c0$datatype
#> [1] "interval"
#> 
#> $c0$pptestcd_cdisc
#> [1] "C0"
#> 
#> $c0$pptest_cdisc
#> [1] "Initial Conc"
#> 
#> 
#> $cmax
#> $cmax$FUN
#> [1] "pk.calc.cmax"
#> 
#> $cmax$values
#> [1] FALSE  TRUE
#> 
#> $cmax$unit_type
#> [1] "conc"
#> 
#> $cmax$pretty_name
#> [1] "Cmax"
#> 
#> $cmax$desc
#> [1] "Maximum observed concentration"
#> 
#> $cmax$sparse
#> [1] FALSE
#> 
#> $cmax$formalsmap
#> list()
#> 
#> $cmax$depends
#> NULL
#> 
#> $cmax$datatype
#> [1] "interval"
#> 
#> $cmax$pptestcd_cdisc
#> [1] "CMAX"
#> 
#> $cmax$pptest_cdisc
#> [1] "Max Conc"
#> 
#> 
#> $cmin
#> $cmin$FUN
#> [1] "pk.calc.cmin"
#> 
#> $cmin$values
#> [1] FALSE  TRUE
#> 
#> $cmin$unit_type
#> [1] "conc"
#> 
#> $cmin$pretty_name
#> [1] "Cmin"
#> 
#> $cmin$desc
#> [1] "Minimum observed concentration"
#> 
#> $cmin$sparse
#> [1] FALSE
#> 
#> $cmin$formalsmap
#> list()
#> 
#> $cmin$depends
#> NULL
#> 
#> $cmin$datatype
#> [1] "interval"
#> 
#> $cmin$pptestcd_cdisc
#> [1] "CMIN"
#> 
#> $cmin$pptest_cdisc
#> [1] "Min Conc"
#> 
#> 
#> $tmax
#> $tmax$FUN
#> [1] "pk.calc.tmax"
#> 
#> $tmax$values
#> [1] FALSE  TRUE
#> 
#> $tmax$unit_type
#> [1] "time"
#> 
#> $tmax$pretty_name
#> [1] "Tmax"
#> 
#> $tmax$desc
#> [1] "Time of the maximum observed concentration"
#> 
#> $tmax$sparse
#> [1] FALSE
#> 
#> $tmax$formalsmap
#> list()
#> 
#> $tmax$depends
#> NULL
#> 
#> $tmax$datatype
#> [1] "interval"
#> 
#> $tmax$pptestcd_cdisc
#> [1] "TMAX"
#> 
#> $tmax$pptest_cdisc
#> [1] "Time of CMAX"
#> 
#> 
#> $tmin
#> $tmin$FUN
#> [1] "pk.calc.tmin"
#> 
#> $tmin$values
#> [1] FALSE  TRUE
#> 
#> $tmin$unit_type
#> [1] "time"
#> 
#> $tmin$pretty_name
#> [1] "Tmin"
#> 
#> $tmin$desc
#> [1] "Time of the minimum observed concentration"
#> 
#> $tmin$sparse
#> [1] FALSE
#> 
#> $tmin$formalsmap
#> list()
#> 
#> $tmin$depends
#> NULL
#> 
#> $tmin$datatype
#> [1] "interval"
#> 
#> $tmin$pptestcd_cdisc
#> [1] "TMIN"
#> 
#> $tmin$pptest_cdisc
#> [1] "Time of CMIN Observation"
#> 
#> 
#> $tlast
#> $tlast$FUN
#> [1] "pk.calc.tlast"
#> 
#> $tlast$values
#> [1] FALSE  TRUE
#> 
#> $tlast$unit_type
#> [1] "time"
#> 
#> $tlast$pretty_name
#> [1] "Tlast"
#> 
#> $tlast$desc
#> [1] "Time of the last concentration observed above the limit of quantification"
#> 
#> $tlast$sparse
#> [1] FALSE
#> 
#> $tlast$formalsmap
#> list()
#> 
#> $tlast$depends
#> NULL
#> 
#> $tlast$datatype
#> [1] "interval"
#> 
#> $tlast$pptestcd_cdisc
#> [1] "TLST"
#> 
#> $tlast$pptest_cdisc
#> [1] "Time of Last Nonzero Conc"
#> 
#> 
#> $tfirst
#> $tfirst$FUN
#> [1] "pk.calc.tfirst"
#> 
#> $tfirst$values
#> [1] FALSE  TRUE
#> 
#> $tfirst$unit_type
#> [1] "time"
#> 
#> $tfirst$pretty_name
#> [1] "Tfirst"
#> 
#> $tfirst$desc
#> [1] "Time of the first concentration above the limit of quantification"
#> 
#> $tfirst$sparse
#> [1] FALSE
#> 
#> $tfirst$formalsmap
#> list()
#> 
#> $tfirst$depends
#> NULL
#> 
#> $tfirst$datatype
#> [1] "interval"
#> 
#> $tfirst$pptestcd_cdisc
#> [1] "TFIRST"
#> 
#> $tfirst$pptest_cdisc
#> [1] "Time of First Nonzero Conc"
#> 
#> 
#> $clast.obs
#> $clast.obs$FUN
#> [1] "pk.calc.clast.obs"
#> 
#> $clast.obs$values
#> [1] FALSE  TRUE
#> 
#> $clast.obs$unit_type
#> [1] "conc"
#> 
#> $clast.obs$pretty_name
#> [1] "Clast"
#> 
#> $clast.obs$desc
#> [1] "The last concentration observed above the limit of quantification"
#> 
#> $clast.obs$sparse
#> [1] FALSE
#> 
#> $clast.obs$formalsmap
#> list()
#> 
#> $clast.obs$depends
#> NULL
#> 
#> $clast.obs$datatype
#> [1] "interval"
#> 
#> $clast.obs$pptestcd_cdisc
#> [1] "CLST"
#> 
#> $clast.obs$pptest_cdisc
#> [1] "Last Nonzero Conc"
#> 
#> 
#> $cl.last
#> $cl.last$FUN
#> [1] "pk.calc.cl"
#> 
#> $cl.last$values
#> [1] FALSE  TRUE
#> 
#> $cl.last$unit_type
#> [1] "clearance"
#> 
#> $cl.last$pretty_name
#> [1] "CL (based on AUClast)"
#> 
#> $cl.last$desc
#> [1] "Clearance or observed oral clearance calculated to Clast"
#> 
#> $cl.last$sparse
#> [1] FALSE
#> 
#> $cl.last$formalsmap
#> $cl.last$formalsmap$auc
#> [1] "auclast"
#> 
#> 
#> $cl.last$depends
#> [1] "auclast"
#> 
#> $cl.last$datatype
#> [1] "interval"
#> 
#> $cl.last$pptestcd_cdisc
#> $cl.last$pptestcd_cdisc$route
#> $cl.last$pptestcd_cdisc$route$extravascular
#> [1] "CLF/FLST"
#> 
#> $cl.last$pptestcd_cdisc$route$intravascular
#> [1] "CLLST"
#> 
#> 
#> 
#> $cl.last$pptest_cdisc
#> $cl.last$pptest_cdisc$route
#> $cl.last$pptest_cdisc$route$extravascular
#> [1] "CL by F (based on AUClast)"
#> 
#> $cl.last$pptest_cdisc$route$intravascular
#> [1] "CL (based on AUClast)"
#> 
#> 
#> 
#> 
#> $cl.all
#> $cl.all$FUN
#> [1] "pk.calc.cl"
#> 
#> $cl.all$values
#> [1] FALSE  TRUE
#> 
#> $cl.all$unit_type
#> [1] "clearance"
#> 
#> $cl.all$pretty_name
#> [1] "CL (based on AUCall)"
#> 
#> $cl.all$desc
#> [1] "Clearance or observed oral clearance calculated with AUCall"
#> 
#> $cl.all$sparse
#> [1] FALSE
#> 
#> $cl.all$formalsmap
#> $cl.all$formalsmap$auc
#> [1] "aucall"
#> 
#> 
#> $cl.all$depends
#> [1] "aucall"
#> 
#> $cl.all$datatype
#> [1] "interval"
#> 
#> $cl.all$pptestcd_cdisc
#> $cl.all$pptestcd_cdisc$route
#> $cl.all$pptestcd_cdisc$route$extravascular
#> [1] "CLF/FALL"
#> 
#> $cl.all$pptestcd_cdisc$route$intravascular
#> [1] "CLALL"
#> 
#> 
#> 
#> $cl.all$pptest_cdisc
#> $cl.all$pptest_cdisc$route
#> $cl.all$pptest_cdisc$route$extravascular
#> [1] "CL by F (based on AUCall)"
#> 
#> $cl.all$pptest_cdisc$route$intravascular
#> [1] "CL (based on AUCall)"
#> 
#> 
#> 
#> 
#> $cl.int.all
#> $cl.int.all$FUN
#> [1] "pk.calc.cl"
#> 
#> $cl.int.all$values
#> [1] FALSE  TRUE
#> 
#> $cl.int.all$unit_type
#> [1] "clearance"
#> 
#> $cl.int.all$pretty_name
#> [1] "CL (based on AUCint.all)"
#> 
#> $cl.int.all$desc
#> [1] "Clearance or observed oral clearance calculated with AUCint.all"
#> 
#> $cl.int.all$sparse
#> [1] FALSE
#> 
#> $cl.int.all$formalsmap
#> $cl.int.all$formalsmap$auc
#> [1] "aucint.all"
#> 
#> 
#> $cl.int.all$depends
#> [1] "aucint.all"
#> 
#> $cl.int.all$datatype
#> [1] "interval"
#> 
#> $cl.int.all$pptestcd_cdisc
#> [1] "cl.int.all"
#> 
#> $cl.int.all$pptest_cdisc
#> [1] "Clearance or observed oral clearance calculated with AUCint.all"
#> 
#> 
#> $cl.int.last
#> $cl.int.last$FUN
#> [1] "pk.calc.cl"
#> 
#> $cl.int.last$values
#> [1] FALSE  TRUE
#> 
#> $cl.int.last$unit_type
#> [1] "clearance"
#> 
#> $cl.int.last$pretty_name
#> [1] "CL (based on AUCint.last)"
#> 
#> $cl.int.last$desc
#> [1] "Clearance or observed oral clearance calculated with AUCint.last"
#> 
#> $cl.int.last$sparse
#> [1] FALSE
#> 
#> $cl.int.last$formalsmap
#> $cl.int.last$formalsmap$auc
#> [1] "aucint.last"
#> 
#> 
#> $cl.int.last$depends
#> [1] "aucint.last"
#> 
#> $cl.int.last$datatype
#> [1] "interval"
#> 
#> $cl.int.last$pptestcd_cdisc
#> [1] "cl.int.last"
#> 
#> $cl.int.last$pptest_cdisc
#> [1] "Clearance or observed oral clearance calculated with AUCint.last"
#> 
#> 
#> $f
#> $f$FUN
#> [1] "pk.calc.f"
#> 
#> $f$values
#> [1] FALSE  TRUE
#> 
#> $f$unit_type
#> [1] "fraction"
#> 
#> $f$pretty_name
#> [1] "Bioavailability"
#> 
#> $f$desc
#> [1] "Bioavailability or relative bioavailability"
#> 
#> $f$sparse
#> [1] FALSE
#> 
#> $f$formalsmap
#> list()
#> 
#> $f$depends
#> NULL
#> 
#> $f$datatype
#> [1] "interval"
#> 
#> $f$pptestcd_cdisc
#> [1] "FAB"
#> 
#> $f$pptest_cdisc
#> [1] "Absolute Bioavailability"
#> 
#> 
#> $mrt.last
#> $mrt.last$FUN
#> [1] "pk.calc.mrt"
#> 
#> $mrt.last$values
#> [1] FALSE  TRUE
#> 
#> $mrt.last$unit_type
#> [1] "time"
#> 
#> $mrt.last$pretty_name
#> [1] "MRT (based on AUClast)"
#> 
#> $mrt.last$desc
#> [1] "The mean residence time to the last observed concentration above the LOQ"
#> 
#> $mrt.last$sparse
#> [1] FALSE
#> 
#> $mrt.last$formalsmap
#> $mrt.last$formalsmap$auc
#> [1] "auclast"
#> 
#> $mrt.last$formalsmap$aumc
#> [1] "aumclast"
#> 
#> 
#> $mrt.last$depends
#> [1] "auclast"  "aumclast"
#> 
#> $mrt.last$datatype
#> [1] "interval"
#> 
#> $mrt.last$pptestcd_cdisc
#> $mrt.last$pptestcd_cdisc$route
#> $mrt.last$pptestcd_cdisc$route$extravascular
#> [1] "MRTEVLST"
#> 
#> $mrt.last$pptestcd_cdisc$route$intravascular
#> [1] "MRTICLST"
#> 
#> 
#> 
#> $mrt.last$pptest_cdisc
#> $mrt.last$pptest_cdisc$route
#> $mrt.last$pptest_cdisc$route$extravascular
#> [1] "MRT Extravasc to Last Nonzero Conc"
#> 
#> $mrt.last$pptest_cdisc$route$intravascular
#> [1] "MRT IV Cont Inf to Last Nonzero Conc"
#> 
#> 
#> 
#> 
#> $mrt.all
#> $mrt.all$FUN
#> [1] "pk.calc.mrt"
#> 
#> $mrt.all$values
#> [1] FALSE  TRUE
#> 
#> $mrt.all$unit_type
#> [1] "time"
#> 
#> $mrt.all$pretty_name
#> [1] "MRT (based on AUCall)"
#> 
#> $mrt.all$desc
#> [1] "Mean residence time calculated with AUCall/AUMCall"
#> 
#> $mrt.all$sparse
#> [1] FALSE
#> 
#> $mrt.all$formalsmap
#> $mrt.all$formalsmap$auc
#> [1] "aucall"
#> 
#> $mrt.all$formalsmap$aumc
#> [1] "aumcall"
#> 
#> 
#> $mrt.all$depends
#> [1] "aucall"  "aumcall"
#> 
#> $mrt.all$datatype
#> [1] "interval"
#> 
#> $mrt.all$pptestcd_cdisc
#> [1] "mrt.all"
#> 
#> $mrt.all$pptest_cdisc
#> [1] "Mean residence time calculated with AUCall/AUMCall"
#> 
#> 
#> $mrt.int.all
#> $mrt.int.all$FUN
#> [1] "pk.calc.mrt"
#> 
#> $mrt.int.all$values
#> [1] FALSE  TRUE
#> 
#> $mrt.int.all$unit_type
#> [1] "time"
#> 
#> $mrt.int.all$pretty_name
#> [1] "MRT (based on AUCint.all)"
#> 
#> $mrt.int.all$desc
#> [1] "Mean residence time over interval calculated with AUCint.all/AUMCint.all"
#> 
#> $mrt.int.all$sparse
#> [1] FALSE
#> 
#> $mrt.int.all$formalsmap
#> $mrt.int.all$formalsmap$auc
#> [1] "aucint.all"
#> 
#> $mrt.int.all$formalsmap$aumc
#> [1] "aumcint.all"
#> 
#> 
#> $mrt.int.all$depends
#> [1] "aucint.all"  "aumcint.all"
#> 
#> $mrt.int.all$datatype
#> [1] "interval"
#> 
#> $mrt.int.all$pptestcd_cdisc
#> [1] "mrt.int.all"
#> 
#> $mrt.int.all$pptest_cdisc
#> [1] "Mean residence time over interval calculated with AUCint.all/AUMCint.all"
#> 
#> 
#> $mrt.int.last
#> $mrt.int.last$FUN
#> [1] "pk.calc.mrt"
#> 
#> $mrt.int.last$values
#> [1] FALSE  TRUE
#> 
#> $mrt.int.last$unit_type
#> [1] "time"
#> 
#> $mrt.int.last$pretty_name
#> [1] "MRT (based on AUCint.last)"
#> 
#> $mrt.int.last$desc
#> [1] "Mean residence time over interval calculated with AUCint.last/AUMCint.last"
#> 
#> $mrt.int.last$sparse
#> [1] FALSE
#> 
#> $mrt.int.last$formalsmap
#> $mrt.int.last$formalsmap$auc
#> [1] "aucint.last"
#> 
#> $mrt.int.last$formalsmap$aumc
#> [1] "aumcint.last"
#> 
#> 
#> $mrt.int.last$depends
#> [1] "aucint.last"  "aumcint.last"
#> 
#> $mrt.int.last$datatype
#> [1] "interval"
#> 
#> $mrt.int.last$pptestcd_cdisc
#> [1] "mrt.int.last"
#> 
#> $mrt.int.last$pptest_cdisc
#> [1] "Mean residence time over interval calculated with AUCint.last/AUMCint.last"
#> 
#> 
#> $mrt.iv.last
#> $mrt.iv.last$FUN
#> [1] "pk.calc.mrt.iv"
#> 
#> $mrt.iv.last$values
#> [1] FALSE  TRUE
#> 
#> $mrt.iv.last$unit_type
#> [1] "time"
#> 
#> $mrt.iv.last$pretty_name
#> [1] "MRT (for IV dosing, based on AUClast)"
#> 
#> $mrt.iv.last$desc
#> [1] "The mean residence time to the last observed concentration above the LOQ correcting for dosing duration"
#> 
#> $mrt.iv.last$sparse
#> [1] FALSE
#> 
#> $mrt.iv.last$formalsmap
#> $mrt.iv.last$formalsmap$auc
#> [1] "auclast"
#> 
#> $mrt.iv.last$formalsmap$aumc
#> [1] "aumclast"
#> 
#> 
#> $mrt.iv.last$depends
#> [1] "auclast"  "aumclast"
#> 
#> $mrt.iv.last$datatype
#> [1] "interval"
#> 
#> $mrt.iv.last$pptestcd_cdisc
#> [1] "MRTIBLST"
#> 
#> $mrt.iv.last$pptest_cdisc
#> [1] "MRT Intravasc to Last Nonzero Conc"
#> 
#> 
#> $vss.last
#> $vss.last$FUN
#> [1] "pk.calc.vss"
#> 
#> $vss.last$values
#> [1] FALSE  TRUE
#> 
#> $vss.last$unit_type
#> [1] "volume"
#> 
#> $vss.last$pretty_name
#> [1] "Vss (based on AUClast)"
#> 
#> $vss.last$desc
#> [1] "The steady-state volume of distribution calculating through Tlast"
#> 
#> $vss.last$sparse
#> [1] FALSE
#> 
#> $vss.last$formalsmap
#> $vss.last$formalsmap$cl
#> [1] "cl.last"
#> 
#> $vss.last$formalsmap$mrt
#> [1] "mrt.last"
#> 
#> 
#> $vss.last$depends
#> [1] "cl.last"  "mrt.last"
#> 
#> $vss.last$datatype
#> [1] "interval"
#> 
#> $vss.last$pptestcd_cdisc
#> $vss.last$pptestcd_cdisc$route
#> $vss.last$pptestcd_cdisc$route$extravascular
#> [1] "VSSF/FLST"
#> 
#> $vss.last$pptestcd_cdisc$route$intravascular
#> [1] "VSSLST"
#> 
#> 
#> 
#> $vss.last$pptest_cdisc
#> $vss.last$pptest_cdisc$route
#> $vss.last$pptest_cdisc$route$extravascular
#> [1] "Vss by F (based on AUClast)"
#> 
#> $vss.last$pptest_cdisc$route$intravascular
#> [1] "Vss (based on AUClast)"
#> 
#> 
#> 
#> 
#> $vss.iv.last
#> $vss.iv.last$FUN
#> [1] "pk.calc.vss"
#> 
#> $vss.iv.last$values
#> [1] FALSE  TRUE
#> 
#> $vss.iv.last$unit_type
#> [1] "volume"
#> 
#> $vss.iv.last$pretty_name
#> [1] "Vss (for IV dosing, based on AUClast)"
#> 
#> $vss.iv.last$desc
#> [1] "The steady-state volume of distribution with intravenous infusion calculating through Tlast"
#> 
#> $vss.iv.last$sparse
#> [1] FALSE
#> 
#> $vss.iv.last$formalsmap
#> $vss.iv.last$formalsmap$cl
#> [1] "cl.last"
#> 
#> $vss.iv.last$formalsmap$mrt
#> [1] "mrt.iv.last"
#> 
#> 
#> $vss.iv.last$depends
#> [1] "cl.last"     "mrt.iv.last"
#> 
#> $vss.iv.last$datatype
#> [1] "interval"
#> 
#> $vss.iv.last$pptestcd_cdisc
#> [1] "VSSIVLST"
#> 
#> $vss.iv.last$pptest_cdisc
#> [1] "Vss (for IV dosing, based on AUClast)"
#> 
#> 
#> $vss.all
#> $vss.all$FUN
#> [1] "pk.calc.vss"
#> 
#> $vss.all$values
#> [1] FALSE  TRUE
#> 
#> $vss.all$unit_type
#> [1] "volume"
#> 
#> $vss.all$pretty_name
#> [1] "Vss (based on AUCall)"
#> 
#> $vss.all$desc
#> [1] "Steady-state volume of distribution calculated with AUCall-based CL and MRT"
#> 
#> $vss.all$sparse
#> [1] FALSE
#> 
#> $vss.all$formalsmap
#> $vss.all$formalsmap$cl
#> [1] "cl.all"
#> 
#> $vss.all$formalsmap$mrt
#> [1] "mrt.all"
#> 
#> 
#> $vss.all$depends
#> [1] "cl.all"  "mrt.all"
#> 
#> $vss.all$datatype
#> [1] "interval"
#> 
#> $vss.all$pptestcd_cdisc
#> [1] "vss.all"
#> 
#> $vss.all$pptest_cdisc
#> [1] "Steady-state volume of distribution calculated with AUCall-based CL and MRT"
#> 
#> 
#> $vss.int.all
#> $vss.int.all$FUN
#> [1] "pk.calc.vss"
#> 
#> $vss.int.all$values
#> [1] FALSE  TRUE
#> 
#> $vss.int.all$unit_type
#> [1] "volume"
#> 
#> $vss.int.all$pretty_name
#> [1] "Vss (based on AUCint.all)"
#> 
#> $vss.int.all$desc
#> [1] "Steady-state volume of distribution using interval AUCint.all"
#> 
#> $vss.int.all$sparse
#> [1] FALSE
#> 
#> $vss.int.all$formalsmap
#> $vss.int.all$formalsmap$cl
#> [1] "cl.int.all"
#> 
#> $vss.int.all$formalsmap$mrt
#> [1] "mrt.int.all"
#> 
#> 
#> $vss.int.all$depends
#> [1] "cl.int.all"  "mrt.int.all"
#> 
#> $vss.int.all$datatype
#> [1] "interval"
#> 
#> $vss.int.all$pptestcd_cdisc
#> [1] "vss.int.all"
#> 
#> $vss.int.all$pptest_cdisc
#> [1] "Steady-state volume of distribution using interval AUCint.all"
#> 
#> 
#> $vss.int.last
#> $vss.int.last$FUN
#> [1] "pk.calc.vss"
#> 
#> $vss.int.last$values
#> [1] FALSE  TRUE
#> 
#> $vss.int.last$unit_type
#> [1] "volume"
#> 
#> $vss.int.last$pretty_name
#> [1] "Vss (based on AUCint.last)"
#> 
#> $vss.int.last$desc
#> [1] "Steady-state volume of distribution using interval AUCint.last"
#> 
#> $vss.int.last$sparse
#> [1] FALSE
#> 
#> $vss.int.last$formalsmap
#> $vss.int.last$formalsmap$cl
#> [1] "cl.int.last"
#> 
#> $vss.int.last$formalsmap$mrt
#> [1] "mrt.int.last"
#> 
#> 
#> $vss.int.last$depends
#> [1] "cl.int.last"  "mrt.int.last"
#> 
#> $vss.int.last$datatype
#> [1] "interval"
#> 
#> $vss.int.last$pptestcd_cdisc
#> [1] "vss.int.last"
#> 
#> $vss.int.last$pptest_cdisc
#> [1] "Steady-state volume of distribution using interval AUCint.last"
#> 
#> 
#> $cav
#> $cav$FUN
#> [1] "pk.calc.cav"
#> 
#> $cav$values
#> [1] FALSE  TRUE
#> 
#> $cav$unit_type
#> [1] "conc"
#> 
#> $cav$pretty_name
#> [1] "Cav"
#> 
#> $cav$desc
#> [1] "The average concentration during an interval (calculated with AUClast)"
#> 
#> $cav$sparse
#> [1] FALSE
#> 
#> $cav$formalsmap
#> $cav$formalsmap$auc
#> [1] "auclast"
#> 
#> 
#> $cav$depends
#> [1] "auclast"
#> 
#> $cav$datatype
#> [1] "interval"
#> 
#> $cav$pptestcd_cdisc
#> [1] "CAVG"
#> 
#> $cav$pptest_cdisc
#> [1] "Average Conc"
#> 
#> 
#> $cav.int.last
#> $cav.int.last$FUN
#> [1] "pk.calc.cav"
#> 
#> $cav.int.last$values
#> [1] FALSE  TRUE
#> 
#> $cav.int.last$unit_type
#> [1] "conc"
#> 
#> $cav.int.last$pretty_name
#> [1] "Cav"
#> 
#> $cav.int.last$desc
#> [1] "The average concentration during an interval (calculated with AUCint.last)"
#> 
#> $cav.int.last$sparse
#> [1] FALSE
#> 
#> $cav.int.last$formalsmap
#> $cav.int.last$formalsmap$auc
#> [1] "aucint.last"
#> 
#> 
#> $cav.int.last$depends
#> [1] "aucint.last"
#> 
#> $cav.int.last$datatype
#> [1] "interval"
#> 
#> $cav.int.last$pptestcd_cdisc
#> [1] "CAVGINT"
#> 
#> $cav.int.last$pptest_cdisc
#> [1] "Average Conc from T1 to T2"
#> 
#> 
#> $cav.int.all
#> $cav.int.all$FUN
#> [1] "pk.calc.cav"
#> 
#> $cav.int.all$values
#> [1] FALSE  TRUE
#> 
#> $cav.int.all$unit_type
#> [1] "conc"
#> 
#> $cav.int.all$pretty_name
#> [1] "Cav"
#> 
#> $cav.int.all$desc
#> [1] "The average concentration during an interval (calculated with AUCint.all)"
#> 
#> $cav.int.all$sparse
#> [1] FALSE
#> 
#> $cav.int.all$formalsmap
#> $cav.int.all$formalsmap$auc
#> [1] "aucint.all"
#> 
#> 
#> $cav.int.all$depends
#> [1] "aucint.all"
#> 
#> $cav.int.all$datatype
#> [1] "interval"
#> 
#> $cav.int.all$pptestcd_cdisc
#> [1] "CAVGINA"
#> 
#> $cav.int.all$pptest_cdisc
#> [1] "Cavg All"
#> 
#> 
#> $ctrough
#> $ctrough$FUN
#> [1] "pk.calc.ctrough"
#> 
#> $ctrough$values
#> [1] FALSE  TRUE
#> 
#> $ctrough$unit_type
#> [1] "conc"
#> 
#> $ctrough$pretty_name
#> [1] "Ctrough"
#> 
#> $ctrough$desc
#> [1] "The trough (end of interval) concentration"
#> 
#> $ctrough$sparse
#> [1] FALSE
#> 
#> $ctrough$formalsmap
#> list()
#> 
#> $ctrough$depends
#> NULL
#> 
#> $ctrough$datatype
#> [1] "interval"
#> 
#> $ctrough$pptestcd_cdisc
#> [1] "CTROUGH"
#> 
#> $ctrough$pptest_cdisc
#> [1] "Conc Trough"
#> 
#> 
#> $cstart
#> $cstart$FUN
#> [1] "pk.calc.cstart"
#> 
#> $cstart$values
#> [1] FALSE  TRUE
#> 
#> $cstart$unit_type
#> [1] "conc"
#> 
#> $cstart$pretty_name
#> [1] "Cstart"
#> 
#> $cstart$desc
#> [1] "The predose concentration"
#> 
#> $cstart$sparse
#> [1] FALSE
#> 
#> $cstart$formalsmap
#> list()
#> 
#> $cstart$depends
#> NULL
#> 
#> $cstart$datatype
#> [1] "interval"
#> 
#> $cstart$pptestcd_cdisc
#> [1] "CSTART"
#> 
#> $cstart$pptest_cdisc
#> [1] "Cstart"
#> 
#> 
#> $ptr
#> $ptr$FUN
#> [1] "pk.calc.ptr"
#> 
#> $ptr$values
#> [1] FALSE  TRUE
#> 
#> $ptr$unit_type
#> [1] "fraction"
#> 
#> $ptr$pretty_name
#> [1] "Peak-to-trough ratio"
#> 
#> $ptr$desc
#> [1] "Peak-to-Trough ratio (fraction)"
#> 
#> $ptr$sparse
#> [1] FALSE
#> 
#> $ptr$formalsmap
#> list()
#> 
#> $ptr$depends
#> [1] "cmax"    "ctrough"
#> 
#> $ptr$datatype
#> [1] "interval"
#> 
#> $ptr$pptestcd_cdisc
#> [1] "PTROUGHR"
#> 
#> $ptr$pptest_cdisc
#> [1] "Peak Trough Ratio"
#> 
#> 
#> $tlag
#> $tlag$FUN
#> [1] "pk.calc.tlag"
#> 
#> $tlag$values
#> [1] FALSE  TRUE
#> 
#> $tlag$unit_type
#> [1] "time"
#> 
#> $tlag$pretty_name
#> [1] "Tlag"
#> 
#> $tlag$desc
#> [1] "Lag time"
#> 
#> $tlag$sparse
#> [1] FALSE
#> 
#> $tlag$formalsmap
#> list()
#> 
#> $tlag$depends
#> NULL
#> 
#> $tlag$datatype
#> [1] "interval"
#> 
#> $tlag$pptestcd_cdisc
#> [1] "TLAG"
#> 
#> $tlag$pptest_cdisc
#> [1] "Time to First Nonzero Conc"
#> 
#> 
#> $deg.fluc
#> $deg.fluc$FUN
#> [1] "pk.calc.deg.fluc"
#> 
#> $deg.fluc$values
#> [1] FALSE  TRUE
#> 
#> $deg.fluc$unit_type
#> [1] "%"
#> 
#> $deg.fluc$pretty_name
#> [1] "Degree of fluctuation"
#> 
#> $deg.fluc$desc
#> [1] "Degree of fluctuation"
#> 
#> $deg.fluc$sparse
#> [1] FALSE
#> 
#> $deg.fluc$formalsmap
#> list()
#> 
#> $deg.fluc$depends
#> [1] "cmax" "cmin" "cav" 
#> 
#> $deg.fluc$datatype
#> [1] "interval"
#> 
#> $deg.fluc$pptestcd_cdisc
#> [1] "DEGFLUC"
#> 
#> $deg.fluc$pptest_cdisc
#> [1] "Degree of fluctuation"
#> 
#> 
#> $swing
#> $swing$FUN
#> [1] "pk.calc.swing"
#> 
#> $swing$values
#> [1] FALSE  TRUE
#> 
#> $swing$unit_type
#> [1] "%"
#> 
#> $swing$pretty_name
#> [1] "Swing"
#> 
#> $swing$desc
#> [1] "Swing relative to Cmin"
#> 
#> $swing$sparse
#> [1] FALSE
#> 
#> $swing$formalsmap
#> list()
#> 
#> $swing$depends
#> [1] "cmax" "cmin"
#> 
#> $swing$datatype
#> [1] "interval"
#> 
#> $swing$pptestcd_cdisc
#> [1] "SWING"
#> 
#> $swing$pptest_cdisc
#> [1] "Swing"
#> 
#> 
#> $ceoi
#> $ceoi$FUN
#> [1] "pk.calc.ceoi"
#> 
#> $ceoi$values
#> [1] FALSE  TRUE
#> 
#> $ceoi$unit_type
#> [1] "conc"
#> 
#> $ceoi$pretty_name
#> [1] "Ceoi"
#> 
#> $ceoi$desc
#> [1] "Concentration at the end of infusion"
#> 
#> $ceoi$sparse
#> [1] FALSE
#> 
#> $ceoi$formalsmap
#> list()
#> 
#> $ceoi$depends
#> NULL
#> 
#> $ceoi$datatype
#> [1] "interval"
#> 
#> $ceoi$pptestcd_cdisc
#> [1] "CEOI"
#> 
#> $ceoi$pptest_cdisc
#> [1] "Ceoi"
#> 
#> 
#> $aucabove.predose.all
#> $aucabove.predose.all$FUN
#> [1] "pk.calc.aucabove"
#> 
#> $aucabove.predose.all$values
#> [1] FALSE  TRUE
#> 
#> $aucabove.predose.all$unit_type
#> [1] "auc"
#> 
#> $aucabove.predose.all$pretty_name
#> [1] "AUC,above"
#> 
#> $aucabove.predose.all$desc
#> [1] "The area under the concentration time the beginning of the interval to the last concentration above the limit of quantification plus the triangle from that last concentration to 0 at the first concentration below the limit of quantification, with a concentration subtracted from all concentrations and values below zero after subtraction set to zero"
#> 
#> $aucabove.predose.all$sparse
#> [1] FALSE
#> 
#> $aucabove.predose.all$formalsmap
#> $aucabove.predose.all$formalsmap$conc_above
#> [1] "cstart"
#> 
#> 
#> $aucabove.predose.all$depends
#> [1] "cstart"
#> 
#> $aucabove.predose.all$datatype
#> [1] "interval"
#> 
#> $aucabove.predose.all$pptestcd_cdisc
#> [1] "AUCABVPA"
#> 
#> $aucabove.predose.all$pptest_cdisc
#> [1] "AUC above predose"
#> 
#> 
#> $aucabove.trough.all
#> $aucabove.trough.all$FUN
#> [1] "pk.calc.aucabove"
#> 
#> $aucabove.trough.all$values
#> [1] FALSE  TRUE
#> 
#> $aucabove.trough.all$unit_type
#> [1] "auc"
#> 
#> $aucabove.trough.all$pretty_name
#> [1] "AUC,above"
#> 
#> $aucabove.trough.all$desc
#> [1] "The area under the concentration time the beginning of the interval to the last concentration above the limit of quantification plus the triangle from that last concentration to 0 at the first concentration below the limit of quantification, with a concentration subtracted from all concentrations and values below zero after subtraction set to zero"
#> 
#> $aucabove.trough.all$sparse
#> [1] FALSE
#> 
#> $aucabove.trough.all$formalsmap
#> $aucabove.trough.all$formalsmap$conc_above
#> [1] "ctrough"
#> 
#> 
#> $aucabove.trough.all$depends
#> [1] "ctrough"
#> 
#> $aucabove.trough.all$datatype
#> [1] "interval"
#> 
#> $aucabove.trough.all$pptestcd_cdisc
#> [1] "AUCABVTA"
#> 
#> $aucabove.trough.all$pptest_cdisc
#> [1] "AUC above trough"
#> 
#> 
#> $count_conc
#> $count_conc$FUN
#> [1] "pk.calc.count_conc"
#> 
#> $count_conc$values
#> [1] FALSE  TRUE
#> 
#> $count_conc$unit_type
#> [1] "count"
#> 
#> $count_conc$pretty_name
#> [1] "Concentration count"
#> 
#> $count_conc$desc
#> [1] "Number of non-missing concentrations for an interval"
#> 
#> $count_conc$sparse
#> [1] FALSE
#> 
#> $count_conc$formalsmap
#> list()
#> 
#> $count_conc$depends
#> NULL
#> 
#> $count_conc$datatype
#> [1] "interval"
#> 
#> $count_conc$pptestcd_cdisc
#> [1] "CNTCONC"
#> 
#> $count_conc$pptest_cdisc
#> [1] "Concentration count"
#> 
#> 
#> $count_conc_measured
#> $count_conc_measured$FUN
#> [1] "pk.calc.count_conc_measured"
#> 
#> $count_conc_measured$values
#> [1] FALSE  TRUE
#> 
#> $count_conc_measured$unit_type
#> [1] "count"
#> 
#> $count_conc_measured$pretty_name
#> [1] "Measured concentration count"
#> 
#> $count_conc_measured$desc
#> [1] "Number of measured and non BLQ/ALQ concentrations for an interval"
#> 
#> $count_conc_measured$sparse
#> [1] FALSE
#> 
#> $count_conc_measured$formalsmap
#> list()
#> 
#> $count_conc_measured$depends
#> NULL
#> 
#> $count_conc_measured$datatype
#> [1] "interval"
#> 
#> $count_conc_measured$pptestcd_cdisc
#> [1] "count_conc_measured"
#> 
#> $count_conc_measured$pptest_cdisc
#> [1] "Number of measured and non BLQ/ALQ concentrations for an interval"
#> 
#> 
#> $totdose
#> $totdose$FUN
#> [1] "pk.calc.totdose"
#> 
#> $totdose$values
#> [1] FALSE  TRUE
#> 
#> $totdose$unit_type
#> [1] "dose"
#> 
#> $totdose$pretty_name
#> [1] "Total dose"
#> 
#> $totdose$desc
#> [1] "Total dose administered during an interval"
#> 
#> $totdose$sparse
#> [1] FALSE
#> 
#> $totdose$formalsmap
#> list()
#> 
#> $totdose$depends
#> NULL
#> 
#> $totdose$datatype
#> [1] "interval"
#> 
#> $totdose$pptestcd_cdisc
#> [1] "TDOSE"
#> 
#> $totdose$pptest_cdisc
#> [1] "Total dose administered"
#> 
#> 
#> $volpk
#> $volpk$FUN
#> [1] "pk.calc.volpk"
#> 
#> $volpk$values
#> [1] FALSE  TRUE
#> 
#> $volpk$unit_type
#> [1] "volume"
#> 
#> $volpk$pretty_name
#> [1] "Total Urine Volume"
#> 
#> $volpk$desc
#> [1] "The sum of urine volumes for the interval"
#> 
#> $volpk$sparse
#> [1] FALSE
#> 
#> $volpk$formalsmap
#> list()
#> 
#> $volpk$depends
#> NULL
#> 
#> $volpk$datatype
#> [1] "interval"
#> 
#> $volpk$pptestcd_cdisc
#> [1] "VOLPK"
#> 
#> $volpk$pptest_cdisc
#> [1] "Volume of PK sample"
#> 
#> 
#> $ae
#> $ae$FUN
#> [1] "pk.calc.ae"
#> 
#> $ae$values
#> [1] FALSE  TRUE
#> 
#> $ae$unit_type
#> [1] "amount"
#> 
#> $ae$pretty_name
#> [1] "Amount excreted"
#> 
#> $ae$desc
#> [1] "The amount excreted (typically into urine or feces)"
#> 
#> $ae$sparse
#> [1] FALSE
#> 
#> $ae$formalsmap
#> list()
#> 
#> $ae$depends
#> NULL
#> 
#> $ae$datatype
#> [1] "interval"
#> 
#> $ae$pptestcd_cdisc
#> [1] "RCAMINT"
#> 
#> $ae$pptest_cdisc
#> [1] "Amt Rec from T1 to T2"
#> 
#> 
#> $clr.last
#> $clr.last$FUN
#> [1] "pk.calc.clr"
#> 
#> $clr.last$values
#> [1] FALSE  TRUE
#> 
#> $clr.last$unit_type
#> [1] "renal_clearance"
#> 
#> $clr.last$pretty_name
#> [1] "Renal clearance (from AUClast)"
#> 
#> $clr.last$desc
#> [1] "The renal clearance calculated using AUClast"
#> 
#> $clr.last$sparse
#> [1] FALSE
#> 
#> $clr.last$formalsmap
#> $clr.last$formalsmap$auc
#> [1] "auclast"
#> 
#> 
#> $clr.last$depends
#> [1] "ae"
#> 
#> $clr.last$datatype
#> [1] "interval"
#> 
#> $clr.last$pptestcd_cdisc
#> [1] "RENALCL"
#> 
#> $clr.last$pptest_cdisc
#> [1] "Renal CL"
#> 
#> 
#> $clr.obs
#> $clr.obs$FUN
#> [1] "pk.calc.clr"
#> 
#> $clr.obs$values
#> [1] FALSE  TRUE
#> 
#> $clr.obs$unit_type
#> [1] "renal_clearance"
#> 
#> $clr.obs$pretty_name
#> [1] "Renal clearance (from AUCinf,obs)"
#> 
#> $clr.obs$desc
#> [1] "The renal clearance calculated using AUCinf,obs"
#> 
#> $clr.obs$sparse
#> [1] FALSE
#> 
#> $clr.obs$formalsmap
#> $clr.obs$formalsmap$auc
#> [1] "aucinf.obs"
#> 
#> 
#> $clr.obs$depends
#> [1] "ae"
#> 
#> $clr.obs$datatype
#> [1] "interval"
#> 
#> $clr.obs$pptestcd_cdisc
#> [1] "RENALCL"
#> 
#> $clr.obs$pptest_cdisc
#> [1] "Renal CL"
#> 
#> 
#> $clr.pred
#> $clr.pred$FUN
#> [1] "pk.calc.clr"
#> 
#> $clr.pred$values
#> [1] FALSE  TRUE
#> 
#> $clr.pred$unit_type
#> [1] "renal_clearance"
#> 
#> $clr.pred$pretty_name
#> [1] "Renal clearance (from AUCinf,pred)"
#> 
#> $clr.pred$desc
#> [1] "The renal clearance calculated using AUCinf,pred"
#> 
#> $clr.pred$sparse
#> [1] FALSE
#> 
#> $clr.pred$formalsmap
#> $clr.pred$formalsmap$auc
#> [1] "aucinf.pred"
#> 
#> 
#> $clr.pred$depends
#> [1] "ae"
#> 
#> $clr.pred$datatype
#> [1] "interval"
#> 
#> $clr.pred$pptestcd_cdisc
#> [1] "RENALCL"
#> 
#> $clr.pred$pptest_cdisc
#> [1] "Renal CL"
#> 
#> 
#> $fe
#> $fe$FUN
#> [1] "pk.calc.fe"
#> 
#> $fe$values
#> [1] FALSE  TRUE
#> 
#> $fe$unit_type
#> [1] "amount_dose"
#> 
#> $fe$pretty_name
#> [1] "Fraction excreted"
#> 
#> $fe$desc
#> [1] "The fraction of the dose excreted"
#> 
#> $fe$sparse
#> [1] FALSE
#> 
#> $fe$formalsmap
#> list()
#> 
#> $fe$depends
#> [1] "ae"
#> 
#> $fe$datatype
#> [1] "interval"
#> 
#> $fe$pptestcd_cdisc
#> [1] "FREXINT"
#> 
#> $fe$pptest_cdisc
#> [1] "Fract Excr from T1 to T2"
#> 
#> 
#> $ertlst
#> $ertlst$FUN
#> [1] "pk.calc.ertlst"
#> 
#> $ertlst$values
#> [1] FALSE  TRUE
#> 
#> $ertlst$unit_type
#> [1] "time"
#> 
#> $ertlst$pretty_name
#> [1] "Tlast excretion rate"
#> 
#> $ertlst$desc
#> [1] "The midpoint collection time of the last measurable excretion rate (typically in urine or feces)"
#> 
#> $ertlst$sparse
#> [1] FALSE
#> 
#> $ertlst$formalsmap
#> list()
#> 
#> $ertlst$depends
#> NULL
#> 
#> $ertlst$datatype
#> [1] "interval"
#> 
#> $ertlst$pptestcd_cdisc
#> [1] "ERTLST"
#> 
#> $ertlst$pptest_cdisc
#> [1] "Time of Last Excretion Rate"
#> 
#> 
#> $ermax
#> $ermax$FUN
#> [1] "pk.calc.ermax"
#> 
#> $ermax$values
#> [1] FALSE  TRUE
#> 
#> $ermax$unit_type
#> [1] "amount_time"
#> 
#> $ermax$pretty_name
#> [1] "Maximum excretion rate"
#> 
#> $ermax$desc
#> [1] "The maximum excretion rate (typically in urine or feces)"
#> 
#> $ermax$sparse
#> [1] FALSE
#> 
#> $ermax$formalsmap
#> list()
#> 
#> $ermax$depends
#> NULL
#> 
#> $ermax$datatype
#> [1] "interval"
#> 
#> $ermax$pptestcd_cdisc
#> [1] "ERMAX"
#> 
#> $ermax$pptest_cdisc
#> [1] "Max Excretion Rate"
#> 
#> 
#> $ertmax
#> $ertmax$FUN
#> [1] "pk.calc.ertmax"
#> 
#> $ertmax$values
#> [1] FALSE  TRUE
#> 
#> $ertmax$unit_type
#> [1] "time"
#> 
#> $ertmax$pretty_name
#> [1] "Tmax excretion rate"
#> 
#> $ertmax$desc
#> [1] "The midpoint collection time of the maximum excretion rate (typically in urine or feces)"
#> 
#> $ertmax$sparse
#> [1] FALSE
#> 
#> $ertmax$formalsmap
#> list()
#> 
#> $ertmax$depends
#> NULL
#> 
#> $ertmax$datatype
#> [1] "interval"
#> 
#> $ertmax$pptestcd_cdisc
#> [1] "ERTMAX"
#> 
#> $ertmax$pptest_cdisc
#> [1] "Midpoint of Interval of Maximum ER"
#> 
#> 
#> $sparse_auclast
#> $sparse_auclast$FUN
#> [1] "pk.calc.sparse_auclast"
#> 
#> $sparse_auclast$values
#> [1] FALSE  TRUE
#> 
#> $sparse_auclast$unit_type
#> [1] "auc"
#> 
#> $sparse_auclast$pretty_name
#> [1] "Sparse AUClast"
#> 
#> $sparse_auclast$desc
#> [1] "For sparse PK sampling, the area under the concentration time curve from the beginning of the interval to the last concentration above the limit of quantification"
#> 
#> $sparse_auclast$sparse
#> [1] TRUE
#> 
#> $sparse_auclast$formalsmap
#> list()
#> 
#> $sparse_auclast$depends
#> NULL
#> 
#> $sparse_auclast$datatype
#> [1] "interval"
#> 
#> $sparse_auclast$pptestcd_cdisc
#> [1] "SPARSEAL"
#> 
#> $sparse_auclast$pptest_cdisc
#> [1] "Sparse AUClast"
#> 
#> 
#> $sparse_auc_se
#> $sparse_auc_se$FUN
#> [1] NA
#> 
#> $sparse_auc_se$values
#> [1] FALSE  TRUE
#> 
#> $sparse_auc_se$unit_type
#> [1] "auc"
#> 
#> $sparse_auc_se$pretty_name
#> [1] "Sparse AUClast standard error"
#> 
#> $sparse_auc_se$desc
#> [1] "For sparse PK sampling, the standard error of the area under the concentration time curve from the beginning of the interval to the last concentration above the limit of quantification"
#> 
#> $sparse_auc_se$sparse
#> [1] FALSE
#> 
#> $sparse_auc_se$formalsmap
#> list()
#> 
#> $sparse_auc_se$depends
#> [1] "sparse_auclast"
#> 
#> $sparse_auc_se$datatype
#> [1] "interval"
#> 
#> $sparse_auc_se$pptestcd_cdisc
#> [1] "SPARSEAS"
#> 
#> $sparse_auc_se$pptest_cdisc
#> [1] "Sparse AUClast standard error"
#> 
#> 
#> $sparse_auc_df
#> $sparse_auc_df$FUN
#> [1] NA
#> 
#> $sparse_auc_df$values
#> [1] FALSE  TRUE
#> 
#> $sparse_auc_df$unit_type
#> [1] "count"
#> 
#> $sparse_auc_df$pretty_name
#> [1] "Sparse AUClast degrees of freedom"
#> 
#> $sparse_auc_df$desc
#> [1] "For sparse PK sampling, the standard error degrees of freedom of the area under the concentration time curve from the beginning of the interval to the last concentration above the limit of quantification"
#> 
#> $sparse_auc_df$sparse
#> [1] FALSE
#> 
#> $sparse_auc_df$formalsmap
#> list()
#> 
#> $sparse_auc_df$depends
#> [1] "sparse_auclast"
#> 
#> $sparse_auc_df$datatype
#> [1] "interval"
#> 
#> $sparse_auc_df$pptestcd_cdisc
#> [1] "SPARSEAD"
#> 
#> $sparse_auc_df$pptest_cdisc
#> [1] "Sparse AUClast degrees of freedom"
#> 
#> 
#> $sparse_aumclast
#> $sparse_aumclast$FUN
#> [1] "pk.calc.sparse_aumclast"
#> 
#> $sparse_aumclast$values
#> [1] FALSE  TRUE
#> 
#> $sparse_aumclast$unit_type
#> [1] "aumc"
#> 
#> $sparse_aumclast$pretty_name
#> [1] "Sparse AUMClast"
#> 
#> $sparse_aumclast$desc
#> [1] "For sparse PK sampling, the area under the moment curve from the beginning of the interval to the last concentration above the limit of quantification"
#> 
#> $sparse_aumclast$sparse
#> [1] TRUE
#> 
#> $sparse_aumclast$formalsmap
#> list()
#> 
#> $sparse_aumclast$depends
#> [1] "sparse_auclast"
#> 
#> $sparse_aumclast$datatype
#> [1] "interval"
#> 
#> $sparse_aumclast$pptestcd_cdisc
#> [1] "sparse_aumclast"
#> 
#> $sparse_aumclast$pptest_cdisc
#> [1] "For sparse PK sampling, the area under the moment curve from the beginning of the interval to the last concentration above the limit of quantification"
#> 
#> 
#> $sparse_aumc_se
#> $sparse_aumc_se$FUN
#> [1] NA
#> 
#> $sparse_aumc_se$values
#> [1] FALSE  TRUE
#> 
#> $sparse_aumc_se$unit_type
#> [1] "aumc"
#> 
#> $sparse_aumc_se$pretty_name
#> [1] "Sparse AUMC standard error"
#> 
#> $sparse_aumc_se$desc
#> [1] "For sparse PK sampling, the standard error of the area under the moment curve"
#> 
#> $sparse_aumc_se$sparse
#> [1] FALSE
#> 
#> $sparse_aumc_se$formalsmap
#> list()
#> 
#> $sparse_aumc_se$depends
#> [1] "sparse_aumclast"
#> 
#> $sparse_aumc_se$datatype
#> [1] "interval"
#> 
#> $sparse_aumc_se$pptestcd_cdisc
#> [1] "sparse_aumc_se"
#> 
#> $sparse_aumc_se$pptest_cdisc
#> [1] "For sparse PK sampling, the standard error of the area under the moment curve"
#> 
#> 
#> $sparse_aumc_df
#> $sparse_aumc_df$FUN
#> [1] NA
#> 
#> $sparse_aumc_df$values
#> [1] FALSE  TRUE
#> 
#> $sparse_aumc_df$unit_type
#> [1] "count"
#> 
#> $sparse_aumc_df$pretty_name
#> [1] "Sparse AUMC degrees of freedom"
#> 
#> $sparse_aumc_df$desc
#> [1] "For sparse PK sampling, the degrees of freedom for the AUMC variance estimate"
#> 
#> $sparse_aumc_df$sparse
#> [1] FALSE
#> 
#> $sparse_aumc_df$formalsmap
#> list()
#> 
#> $sparse_aumc_df$depends
#> [1] "sparse_aumclast"
#> 
#> $sparse_aumc_df$datatype
#> [1] "interval"
#> 
#> $sparse_aumc_df$pptestcd_cdisc
#> [1] "sparse_aumc_df"
#> 
#> $sparse_aumc_df$pptest_cdisc
#> [1] "For sparse PK sampling, the degrees of freedom for the AUMC variance estimate"
#> 
#> 
#> $time_above
#> $time_above$FUN
#> [1] "pk.calc.time_above"
#> 
#> $time_above$values
#> [1] FALSE  TRUE
#> 
#> $time_above$unit_type
#> [1] "time"
#> 
#> $time_above$pretty_name
#> [1] "Time above Concentration"
#> 
#> $time_above$desc
#> [1] "Time above a given concentration"
#> 
#> $time_above$sparse
#> [1] FALSE
#> 
#> $time_above$formalsmap
#> list()
#> 
#> $time_above$depends
#> NULL
#> 
#> $time_above$datatype
#> [1] "interval"
#> 
#> $time_above$pptestcd_cdisc
#> [1] "TAT"
#> 
#> $time_above$pptest_cdisc
#> [1] "Time Above Threshold"
#> 
#> 
#> $aucivlast
#> $aucivlast$FUN
#> [1] "pk.calc.auciv"
#> 
#> $aucivlast$values
#> [1] FALSE  TRUE
#> 
#> $aucivlast$unit_type
#> [1] "auc"
#> 
#> $aucivlast$pretty_name
#> [1] "AUClast (IV dosing)"
#> 
#> $aucivlast$desc
#> [1] "The AUClast calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#> 
#> $aucivlast$sparse
#> [1] FALSE
#> 
#> $aucivlast$formalsmap
#> $aucivlast$formalsmap$auc
#> [1] "auclast"
#> 
#> 
#> $aucivlast$depends
#> [1] "auclast" "c0"     
#> 
#> $aucivlast$datatype
#> [1] "interval"
#> 
#> $aucivlast$pptestcd_cdisc
#> [1] "AUCIVLST"
#> 
#> $aucivlast$pptest_cdisc
#> [1] "AUClast (IV dosing)"
#> 
#> 
#> $aucivall
#> $aucivall$FUN
#> [1] "pk.calc.auciv"
#> 
#> $aucivall$values
#> [1] FALSE  TRUE
#> 
#> $aucivall$unit_type
#> [1] "auc"
#> 
#> $aucivall$pretty_name
#> [1] "AUCall (IV dosing)"
#> 
#> $aucivall$desc
#> [1] "The AUCall calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#> 
#> $aucivall$sparse
#> [1] FALSE
#> 
#> $aucivall$formalsmap
#> $aucivall$formalsmap$auc
#> [1] "aucall"
#> 
#> 
#> $aucivall$depends
#> [1] "aucall" "c0"    
#> 
#> $aucivall$datatype
#> [1] "interval"
#> 
#> $aucivall$pptestcd_cdisc
#> [1] "AUCIVA"
#> 
#> $aucivall$pptest_cdisc
#> [1] "AUCall (IV dosing)"
#> 
#> 
#> $aucivint.last
#> $aucivint.last$FUN
#> [1] "pk.calc.auciv"
#> 
#> $aucivint.last$values
#> [1] FALSE  TRUE
#> 
#> $aucivint.last$unit_type
#> [1] "auc"
#> 
#> $aucivint.last$pretty_name
#> [1] "AUCint,last (IV dosing)"
#> 
#> $aucivint.last$desc
#> [1] "The AUCint,last calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#> 
#> $aucivint.last$sparse
#> [1] FALSE
#> 
#> $aucivint.last$formalsmap
#> $aucivint.last$formalsmap$auc
#> [1] "aucint.last"
#> 
#> 
#> $aucivint.last$depends
#> [1] "aucint.last" "c0"         
#> 
#> $aucivint.last$datatype
#> [1] "interval"
#> 
#> $aucivint.last$pptestcd_cdisc
#> [1] "AUCIVILT"
#> 
#> $aucivint.last$pptest_cdisc
#> [1] "AUCint,last (IV dosing)"
#> 
#> 
#> $aucivint.all
#> $aucivint.all$FUN
#> [1] "pk.calc.auciv"
#> 
#> $aucivint.all$values
#> [1] FALSE  TRUE
#> 
#> $aucivint.all$unit_type
#> [1] "auc"
#> 
#> $aucivint.all$pretty_name
#> [1] "AUCint,all (IV dosing)"
#> 
#> $aucivint.all$desc
#> [1] "The AUCint,all calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#> 
#> $aucivint.all$sparse
#> [1] FALSE
#> 
#> $aucivint.all$formalsmap
#> $aucivint.all$formalsmap$auc
#> [1] "aucint.all"
#> 
#> 
#> $aucivint.all$depends
#> [1] "aucint.all" "c0"        
#> 
#> $aucivint.all$datatype
#> [1] "interval"
#> 
#> $aucivint.all$pptestcd_cdisc
#> [1] "AUCIVINA"
#> 
#> $aucivint.all$pptest_cdisc
#> [1] "AUCint,all (IV dosing)"
#> 
#> 
#> $aucivpbextlast
#> $aucivpbextlast$FUN
#> [1] "pk.calc.auciv_pbext"
#> 
#> $aucivpbextlast$values
#> [1] FALSE  TRUE
#> 
#> $aucivpbextlast$unit_type
#> [1] "%"
#> 
#> $aucivpbextlast$pretty_name
#> [1] "AUCbext (based on AUClast)"
#> 
#> $aucivpbextlast$desc
#> [1] "The back-extrapolation percent for intravenous dosing based on AUClast"
#> 
#> $aucivpbextlast$sparse
#> [1] FALSE
#> 
#> $aucivpbextlast$formalsmap
#> $aucivpbextlast$formalsmap$auc
#> [1] "auclast"
#> 
#> $aucivpbextlast$formalsmap$auciv
#> [1] "aucivlast"
#> 
#> 
#> $aucivpbextlast$depends
#> [1] "auclast"   "aucivlast"
#> 
#> $aucivpbextlast$datatype
#> [1] "interval"
#> 
#> $aucivpbextlast$pptestcd_cdisc
#> [1] "AUCIVPLT"
#> 
#> $aucivpbextlast$pptest_cdisc
#> [1] "AUCbext (based on AUClast)"
#> 
#> 
#> $aucivpbextall
#> $aucivpbextall$FUN
#> [1] "pk.calc.auciv_pbext"
#> 
#> $aucivpbextall$values
#> [1] FALSE  TRUE
#> 
#> $aucivpbextall$unit_type
#> [1] "%"
#> 
#> $aucivpbextall$pretty_name
#> [1] "AUCbext (based on AUCall)"
#> 
#> $aucivpbextall$desc
#> [1] "The back-extrapolation percent for intravenous dosing based on AUCall"
#> 
#> $aucivpbextall$sparse
#> [1] FALSE
#> 
#> $aucivpbextall$formalsmap
#> $aucivpbextall$formalsmap$auc
#> [1] "aucall"
#> 
#> $aucivpbextall$formalsmap$auciv
#> [1] "aucivall"
#> 
#> 
#> $aucivpbextall$depends
#> [1] "aucall"   "aucivall"
#> 
#> $aucivpbextall$datatype
#> [1] "interval"
#> 
#> $aucivpbextall$pptestcd_cdisc
#> [1] "AUCIVPEA"
#> 
#> $aucivpbextall$pptest_cdisc
#> [1] "AUCbext (based on AUCall)"
#> 
#> 
#> $aucivpbextint.last
#> $aucivpbextint.last$FUN
#> [1] "pk.calc.auciv_pbext"
#> 
#> $aucivpbextint.last$values
#> [1] FALSE  TRUE
#> 
#> $aucivpbextint.last$unit_type
#> [1] "%"
#> 
#> $aucivpbextint.last$pretty_name
#> [1] "AUCbext (based on AUCint,last)"
#> 
#> $aucivpbextint.last$desc
#> [1] "The back-extrapolation percent for intravenous dosing based on AUCint,last"
#> 
#> $aucivpbextint.last$sparse
#> [1] FALSE
#> 
#> $aucivpbextint.last$formalsmap
#> $aucivpbextint.last$formalsmap$auc
#> [1] "aucint.last"
#> 
#> $aucivpbextint.last$formalsmap$auciv
#> [1] "aucivint.last"
#> 
#> 
#> $aucivpbextint.last$depends
#> [1] "aucint.last"   "aucivint.last"
#> 
#> $aucivpbextint.last$datatype
#> [1] "interval"
#> 
#> $aucivpbextint.last$pptestcd_cdisc
#> [1] "AUCIVPIL"
#> 
#> $aucivpbextint.last$pptest_cdisc
#> [1] "AUCbext (based on AUCint,last)"
#> 
#> 
#> $aucivpbextint.all
#> $aucivpbextint.all$FUN
#> [1] "pk.calc.auciv_pbext"
#> 
#> $aucivpbextint.all$values
#> [1] FALSE  TRUE
#> 
#> $aucivpbextint.all$unit_type
#> [1] "%"
#> 
#> $aucivpbextint.all$pretty_name
#> [1] "AUCbext (based on AUCint,all)"
#> 
#> $aucivpbextint.all$desc
#> [1] "The back-extrapolation percent for intravenous dosing based on AUCint,all"
#> 
#> $aucivpbextint.all$sparse
#> [1] FALSE
#> 
#> $aucivpbextint.all$formalsmap
#> $aucivpbextint.all$formalsmap$auc
#> [1] "aucint.all"
#> 
#> $aucivpbextint.all$formalsmap$auciv
#> [1] "aucivint.all"
#> 
#> 
#> $aucivpbextint.all$depends
#> [1] "aucint.all"   "aucivint.all"
#> 
#> $aucivpbextint.all$datatype
#> [1] "interval"
#> 
#> $aucivpbextint.all$pptestcd_cdisc
#> [1] "AUCIVPIA"
#> 
#> $aucivpbextint.all$pptest_cdisc
#> [1] "AUCbext (based on AUCint,all)"
#> 
#> 
#> $aumcivlast
#> $aumcivlast$FUN
#> [1] "pk.calc.aumciv"
#> 
#> $aumcivlast$values
#> [1] FALSE  TRUE
#> 
#> $aumcivlast$unit_type
#> [1] "aumc"
#> 
#> $aumcivlast$pretty_name
#> [1] "AUMClast (IV dosing)"
#> 
#> $aumcivlast$desc
#> [1] "The AUMClast calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#> 
#> $aumcivlast$sparse
#> [1] FALSE
#> 
#> $aumcivlast$formalsmap
#> $aumcivlast$formalsmap$aumc
#> [1] "aumclast"
#> 
#> 
#> $aumcivlast$depends
#> [1] "aumclast" "c0"      
#> 
#> $aumcivlast$datatype
#> [1] "interval"
#> 
#> $aumcivlast$pptestcd_cdisc
#> [1] "aumcivlast"
#> 
#> $aumcivlast$pptest_cdisc
#> [1] "The AUMClast calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#> 
#> 
#> $aumcivall
#> $aumcivall$FUN
#> [1] "pk.calc.aumciv"
#> 
#> $aumcivall$values
#> [1] FALSE  TRUE
#> 
#> $aumcivall$unit_type
#> [1] "aumc"
#> 
#> $aumcivall$pretty_name
#> [1] "AUMCall (IV dosing)"
#> 
#> $aumcivall$desc
#> [1] "The AUMCall calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#> 
#> $aumcivall$sparse
#> [1] FALSE
#> 
#> $aumcivall$formalsmap
#> $aumcivall$formalsmap$aumc
#> [1] "aumcall"
#> 
#> 
#> $aumcivall$depends
#> [1] "aumcall" "c0"     
#> 
#> $aumcivall$datatype
#> [1] "interval"
#> 
#> $aumcivall$pptestcd_cdisc
#> [1] "aumcivall"
#> 
#> $aumcivall$pptest_cdisc
#> [1] "The AUMCall calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#> 
#> 
#> $aumcivint.last
#> $aumcivint.last$FUN
#> [1] "pk.calc.aumciv"
#> 
#> $aumcivint.last$values
#> [1] FALSE  TRUE
#> 
#> $aumcivint.last$unit_type
#> [1] "aumc"
#> 
#> $aumcivint.last$pretty_name
#> [1] "AUMCint,last (IV dosing)"
#> 
#> $aumcivint.last$desc
#> [1] "The AUMCint,last calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#> 
#> $aumcivint.last$sparse
#> [1] FALSE
#> 
#> $aumcivint.last$formalsmap
#> $aumcivint.last$formalsmap$aumc
#> [1] "aumcint.last"
#> 
#> 
#> $aumcivint.last$depends
#> [1] "aumcint.last" "c0"          
#> 
#> $aumcivint.last$datatype
#> [1] "interval"
#> 
#> $aumcivint.last$pptestcd_cdisc
#> [1] "aumcivint.last"
#> 
#> $aumcivint.last$pptest_cdisc
#> [1] "The AUMCint,last calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#> 
#> 
#> $aumcivint.all
#> $aumcivint.all$FUN
#> [1] "pk.calc.aumciv"
#> 
#> $aumcivint.all$values
#> [1] FALSE  TRUE
#> 
#> $aumcivint.all$unit_type
#> [1] "aumc"
#> 
#> $aumcivint.all$pretty_name
#> [1] "AUMCint,all (IV dosing)"
#> 
#> $aumcivint.all$desc
#> [1] "The AUMCint,all calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#> 
#> $aumcivint.all$sparse
#> [1] FALSE
#> 
#> $aumcivint.all$formalsmap
#> $aumcivint.all$formalsmap$aumc
#> [1] "aumcint.all"
#> 
#> 
#> $aumcivint.all$depends
#> [1] "aumcint.all" "c0"         
#> 
#> $aumcivint.all$datatype
#> [1] "interval"
#> 
#> $aumcivint.all$pptestcd_cdisc
#> [1] "aumcivint.all"
#> 
#> $aumcivint.all$pptest_cdisc
#> [1] "The AUMCint,all calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#> 
#> 
#> $half.life
#> $half.life$FUN
#> [1] "pk.calc.half.life"
#> 
#> $half.life$values
#> [1] FALSE  TRUE
#> 
#> $half.life$unit_type
#> [1] "time"
#> 
#> $half.life$pretty_name
#> [1] "Half-life"
#> 
#> $half.life$desc
#> [1] "The (terminal) half-life"
#> 
#> $half.life$sparse
#> [1] FALSE
#> 
#> $half.life$formalsmap
#> list()
#> 
#> $half.life$depends
#> [1] "tmax"  "tlast"
#> 
#> $half.life$datatype
#> [1] "interval"
#> 
#> $half.life$pptestcd_cdisc
#> [1] "LAMZHL"
#> 
#> $half.life$pptest_cdisc
#> [1] "Half-Life Lambda z"
#> 
#> 
#> $r.squared
#> $r.squared$FUN
#> [1] NA
#> 
#> $r.squared$values
#> [1] FALSE  TRUE
#> 
#> $r.squared$unit_type
#> [1] "unitless"
#> 
#> $r.squared$pretty_name
#> [1] "$r^2$"
#> 
#> $r.squared$desc
#> [1] "The r^2 value of the half-life calculation"
#> 
#> $r.squared$sparse
#> [1] FALSE
#> 
#> $r.squared$formalsmap
#> list()
#> 
#> $r.squared$depends
#> [1] "half.life"
#> 
#> $r.squared$datatype
#> [1] "interval"
#> 
#> $r.squared$pptestcd_cdisc
#> [1] "R2"
#> 
#> $r.squared$pptest_cdisc
#> [1] "R Squared"
#> 
#> 
#> $adj.r.squared
#> $adj.r.squared$FUN
#> [1] NA
#> 
#> $adj.r.squared$values
#> [1] FALSE  TRUE
#> 
#> $adj.r.squared$unit_type
#> [1] "unitless"
#> 
#> $adj.r.squared$pretty_name
#> [1] "$r^2_{adj}$"
#> 
#> $adj.r.squared$desc
#> [1] "The adjusted r^2 value of the half-life calculation"
#> 
#> $adj.r.squared$sparse
#> [1] FALSE
#> 
#> $adj.r.squared$formalsmap
#> list()
#> 
#> $adj.r.squared$depends
#> [1] "half.life"
#> 
#> $adj.r.squared$datatype
#> [1] "interval"
#> 
#> $adj.r.squared$pptestcd_cdisc
#> [1] "R2ADJ"
#> 
#> $adj.r.squared$pptest_cdisc
#> [1] "R Squared Adjusted"
#> 
#> 
#> $lambda.z.corrxy
#> $lambda.z.corrxy$FUN
#> [1] NA
#> 
#> $lambda.z.corrxy$values
#> [1] FALSE  TRUE
#> 
#> $lambda.z.corrxy$unit_type
#> [1] "unitless"
#> 
#> $lambda.z.corrxy$pretty_name
#> [1] "Correlation (time, log-conc)"
#> 
#> $lambda.z.corrxy$desc
#> [1] "Correlation between time and log-concentration for lambda.z points"
#> 
#> $lambda.z.corrxy$sparse
#> [1] FALSE
#> 
#> $lambda.z.corrxy$formalsmap
#> list()
#> 
#> $lambda.z.corrxy$depends
#> [1] "half.life"
#> 
#> $lambda.z.corrxy$datatype
#> [1] "interval"
#> 
#> $lambda.z.corrxy$pptestcd_cdisc
#> [1] "CORRXY"
#> 
#> $lambda.z.corrxy$pptest_cdisc
#> [1] "Correlation Between TimeX and Log ConcY"
#> 
#> 
#> $lambda.z
#> $lambda.z$FUN
#> [1] NA
#> 
#> $lambda.z$values
#> [1] FALSE  TRUE
#> 
#> $lambda.z$unit_type
#> [1] "inverse_time"
#> 
#> $lambda.z$pretty_name
#> [1] "$\\lambda_z$"
#> 
#> $lambda.z$desc
#> [1] "The elimination rate of the terminal half-life"
#> 
#> $lambda.z$sparse
#> [1] FALSE
#> 
#> $lambda.z$formalsmap
#> list()
#> 
#> $lambda.z$depends
#> [1] "half.life"
#> 
#> $lambda.z$datatype
#> [1] "interval"
#> 
#> $lambda.z$pptestcd_cdisc
#> [1] "LAMZ"
#> 
#> $lambda.z$pptest_cdisc
#> [1] "Lambda z"
#> 
#> 
#> $lambda.z.time.first
#> $lambda.z.time.first$FUN
#> [1] NA
#> 
#> $lambda.z.time.first$values
#> [1] FALSE  TRUE
#> 
#> $lambda.z.time.first$unit_type
#> [1] "time"
#> 
#> $lambda.z.time.first$pretty_name
#> [1] "First time for $\\lambda_z$"
#> 
#> $lambda.z.time.first$desc
#> [1] "The first time point used for the calculation of half-life"
#> 
#> $lambda.z.time.first$sparse
#> [1] FALSE
#> 
#> $lambda.z.time.first$formalsmap
#> list()
#> 
#> $lambda.z.time.first$depends
#> [1] "half.life"
#> 
#> $lambda.z.time.first$datatype
#> [1] "interval"
#> 
#> $lambda.z.time.first$pptestcd_cdisc
#> [1] "LAMZLL"
#> 
#> $lambda.z.time.first$pptest_cdisc
#> [1] "Lambda z Lower Limit"
#> 
#> 
#> $lambda.z.time.last
#> $lambda.z.time.last$FUN
#> [1] NA
#> 
#> $lambda.z.time.last$values
#> [1] FALSE  TRUE
#> 
#> $lambda.z.time.last$unit_type
#> [1] "time"
#> 
#> $lambda.z.time.last$pretty_name
#> [1] "Last time for $\\lambda_z$"
#> 
#> $lambda.z.time.last$desc
#> [1] "The last time point used for the calculation of half-life"
#> 
#> $lambda.z.time.last$sparse
#> [1] FALSE
#> 
#> $lambda.z.time.last$formalsmap
#> list()
#> 
#> $lambda.z.time.last$depends
#> [1] "half.life"
#> 
#> $lambda.z.time.last$datatype
#> [1] "interval"
#> 
#> $lambda.z.time.last$pptestcd_cdisc
#> [1] "LAMZUL"
#> 
#> $lambda.z.time.last$pptest_cdisc
#> [1] "Lambda z Upper Limit"
#> 
#> 
#> $lambda.z.n.points
#> $lambda.z.n.points$FUN
#> [1] NA
#> 
#> $lambda.z.n.points$values
#> [1] FALSE  TRUE
#> 
#> $lambda.z.n.points$unit_type
#> [1] "count"
#> 
#> $lambda.z.n.points$pretty_name
#> [1] "Number of points used for lambda_z"
#> 
#> $lambda.z.n.points$desc
#> [1] "The number of points used for the calculation of half-life"
#> 
#> $lambda.z.n.points$sparse
#> [1] FALSE
#> 
#> $lambda.z.n.points$formalsmap
#> list()
#> 
#> $lambda.z.n.points$depends
#> [1] "half.life"
#> 
#> $lambda.z.n.points$datatype
#> [1] "interval"
#> 
#> $lambda.z.n.points$pptestcd_cdisc
#> [1] "LAMZNPT"
#> 
#> $lambda.z.n.points$pptest_cdisc
#> [1] "Number of Points for Lambda z"
#> 
#> 
#> $clast.pred
#> $clast.pred$FUN
#> [1] NA
#> 
#> $clast.pred$values
#> [1] FALSE  TRUE
#> 
#> $clast.pred$unit_type
#> [1] "conc"
#> 
#> $clast.pred$pretty_name
#> [1] "Clast,pred"
#> 
#> $clast.pred$desc
#> [1] "The concentration at Tlast as predicted by the half-life"
#> 
#> $clast.pred$sparse
#> [1] FALSE
#> 
#> $clast.pred$formalsmap
#> list()
#> 
#> $clast.pred$depends
#> [1] "half.life"
#> 
#> $clast.pred$datatype
#> [1] "interval"
#> 
#> $clast.pred$pptestcd_cdisc
#> [1] "CLSTP"
#> 
#> $clast.pred$pptest_cdisc
#> [1] "Clast pred"
#> 
#> 
#> $span.ratio
#> $span.ratio$FUN
#> [1] NA
#> 
#> $span.ratio$values
#> [1] FALSE  TRUE
#> 
#> $span.ratio$unit_type
#> [1] "fraction"
#> 
#> $span.ratio$pretty_name
#> [1] "Span ratio"
#> 
#> $span.ratio$desc
#> [1] "The ratio of the half-life to the duration used for half-life calculation"
#> 
#> $span.ratio$sparse
#> [1] FALSE
#> 
#> $span.ratio$formalsmap
#> list()
#> 
#> $span.ratio$depends
#> [1] "half.life"
#> 
#> $span.ratio$datatype
#> [1] "interval"
#> 
#> $span.ratio$pptestcd_cdisc
#> [1] "LAMZSPN"
#> 
#> $span.ratio$pptest_cdisc
#> [1] "Lambda z Span"
#> 
#> 
#> $tobit_residual
#> $tobit_residual$FUN
#> [1] NA
#> 
#> $tobit_residual$values
#> [1] FALSE  TRUE
#> 
#> $tobit_residual$unit_type
#> [1] "unitless"
#> 
#> $tobit_residual$pretty_name
#> [1] "Tobit residual SD"
#> 
#> $tobit_residual$desc
#> [1] "The estimated residual standard deviation (on the log-concentration scale) from the Tobit half-life fit"
#> 
#> $tobit_residual$sparse
#> [1] FALSE
#> 
#> $tobit_residual$formalsmap
#> list()
#> 
#> $tobit_residual$depends
#> [1] "half.life"
#> 
#> $tobit_residual$datatype
#> [1] "interval"
#> 
#> $tobit_residual$pptestcd_cdisc
#> [1] "tobit_residual"
#> 
#> $tobit_residual$pptest_cdisc
#> [1] "The estimated residual standard deviation (on the log-concentration scale) from the Tobit half-life fit"
#> 
#> 
#> $adj_tobit_residual
#> $adj_tobit_residual$FUN
#> [1] NA
#> 
#> $adj_tobit_residual$values
#> [1] FALSE  TRUE
#> 
#> $adj_tobit_residual$unit_type
#> [1] "unitless"
#> 
#> $adj_tobit_residual$pretty_name
#> [1] "Adjusted Tobit residual SD"
#> 
#> $adj_tobit_residual$desc
#> [1] "The adjusted Tobit residual standard deviation (analogous to adjusted r-squared; penalizes smaller windows)"
#> 
#> $adj_tobit_residual$sparse
#> [1] FALSE
#> 
#> $adj_tobit_residual$formalsmap
#> list()
#> 
#> $adj_tobit_residual$depends
#> [1] "half.life"
#> 
#> $adj_tobit_residual$datatype
#> [1] "interval"
#> 
#> $adj_tobit_residual$pptestcd_cdisc
#> [1] "adj_tobit_residual"
#> 
#> $adj_tobit_residual$pptest_cdisc
#> [1] "The adjusted Tobit residual standard deviation (analogous to adjusted r-squared; penalizes smaller windows)"
#> 
#> 
#> $lambda.z.n.points_blq
#> $lambda.z.n.points_blq$FUN
#> [1] NA
#> 
#> $lambda.z.n.points_blq$values
#> [1] FALSE  TRUE
#> 
#> $lambda.z.n.points_blq$unit_type
#> [1] "count"
#> 
#> $lambda.z.n.points_blq$pretty_name
#> [1] "Number of BLQ points for lambda_z (Tobit)"
#> 
#> $lambda.z.n.points_blq$desc
#> [1] "The number of BLQ points included in the Tobit half-life calculation"
#> 
#> $lambda.z.n.points_blq$sparse
#> [1] FALSE
#> 
#> $lambda.z.n.points_blq$formalsmap
#> list()
#> 
#> $lambda.z.n.points_blq$depends
#> [1] "half.life"
#> 
#> $lambda.z.n.points_blq$datatype
#> [1] "interval"
#> 
#> $lambda.z.n.points_blq$pptestcd_cdisc
#> [1] "lambda.z.n.points_blq"
#> 
#> $lambda.z.n.points_blq$pptest_cdisc
#> [1] "The number of BLQ points included in the Tobit half-life calculation"
#> 
#> 
#> $thalf.eff.last
#> $thalf.eff.last$FUN
#> [1] "pk.calc.thalf.eff"
#> 
#> $thalf.eff.last$values
#> [1] FALSE  TRUE
#> 
#> $thalf.eff.last$unit_type
#> [1] "time"
#> 
#> $thalf.eff.last$pretty_name
#> [1] "Effective half-life (based on MRT,last)"
#> 
#> $thalf.eff.last$desc
#> [1] "The effective half-life (as determined from the MRTlast)"
#> 
#> $thalf.eff.last$sparse
#> [1] FALSE
#> 
#> $thalf.eff.last$formalsmap
#> $thalf.eff.last$formalsmap$mrt
#> [1] "mrt.last"
#> 
#> 
#> $thalf.eff.last$depends
#> [1] "mrt.last"
#> 
#> $thalf.eff.last$datatype
#> [1] "interval"
#> 
#> $thalf.eff.last$pptestcd_cdisc
#> [1] "EFFHL"
#> 
#> $thalf.eff.last$pptest_cdisc
#> [1] "Effective Half-Life (based on AUClast)"
#> 
#> 
#> $thalf.eff.iv.last
#> $thalf.eff.iv.last$FUN
#> [1] "pk.calc.thalf.eff"
#> 
#> $thalf.eff.iv.last$values
#> [1] FALSE  TRUE
#> 
#> $thalf.eff.iv.last$unit_type
#> [1] "time"
#> 
#> $thalf.eff.iv.last$pretty_name
#> [1] "Effective half-life (for IV dosing, based on MRTlast)"
#> 
#> $thalf.eff.iv.last$desc
#> [1] "The effective half-life (as determined from the intravenous MRTlast)"
#> 
#> $thalf.eff.iv.last$sparse
#> [1] FALSE
#> 
#> $thalf.eff.iv.last$formalsmap
#> $thalf.eff.iv.last$formalsmap$mrt
#> [1] "mrt.iv.last"
#> 
#> 
#> $thalf.eff.iv.last$depends
#> [1] "mrt.iv.last"
#> 
#> $thalf.eff.iv.last$datatype
#> [1] "interval"
#> 
#> $thalf.eff.iv.last$pptestcd_cdisc
#> [1] "EFFIVLHL"
#> 
#> $thalf.eff.iv.last$pptest_cdisc
#> [1] "Effective Half-Life (for IV dosing, based on AUClast)"
#> 
#> 
#> $kel.last
#> $kel.last$FUN
#> [1] "pk.calc.kel"
#> 
#> $kel.last$values
#> [1] FALSE  TRUE
#> 
#> $kel.last$unit_type
#> [1] "inverse_time"
#> 
#> $kel.last$pretty_name
#> [1] "Kel (based on AUClast)"
#> 
#> $kel.last$desc
#> [1] "Elimination rate (as calculated from the MRT using AUClast)"
#> 
#> $kel.last$sparse
#> [1] FALSE
#> 
#> $kel.last$formalsmap
#> $kel.last$formalsmap$mrt
#> [1] "mrt.last"
#> 
#> 
#> $kel.last$depends
#> [1] "mrt.last"
#> 
#> $kel.last$datatype
#> [1] "interval"
#> 
#> $kel.last$pptestcd_cdisc
#> [1] "KELLST"
#> 
#> $kel.last$pptest_cdisc
#> [1] "Kel (based on AUClast)"
#> 
#> 
#> $kel.iv.last
#> $kel.iv.last$FUN
#> [1] "pk.calc.kel"
#> 
#> $kel.iv.last$values
#> [1] FALSE  TRUE
#> 
#> $kel.iv.last$unit_type
#> [1] "inverse_time"
#> 
#> $kel.iv.last$pretty_name
#> [1] "Kel (for IV dosing, based on AUClast)"
#> 
#> $kel.iv.last$desc
#> [1] "Elimination rate (as calculated from the intravenous MRTlast)"
#> 
#> $kel.iv.last$sparse
#> [1] FALSE
#> 
#> $kel.iv.last$formalsmap
#> $kel.iv.last$formalsmap$mrt
#> [1] "mrt.iv.last"
#> 
#> 
#> $kel.iv.last$depends
#> [1] "mrt.iv.last"
#> 
#> $kel.iv.last$datatype
#> [1] "interval"
#> 
#> $kel.iv.last$pptestcd_cdisc
#> [1] "KELIVLT"
#> 
#> $kel.iv.last$pptest_cdisc
#> [1] "Kel (for IV dosing, based on AUClast)"
#> 
#> 
#> $kel.all
#> $kel.all$FUN
#> [1] "pk.calc.kel"
#> 
#> $kel.all$values
#> [1] FALSE  TRUE
#> 
#> $kel.all$unit_type
#> [1] "inverse_time"
#> 
#> $kel.all$pretty_name
#> [1] "Kel (based on AUCall)"
#> 
#> $kel.all$desc
#> [1] "Elimination rate (as calculated from the MRTall)"
#> 
#> $kel.all$sparse
#> [1] FALSE
#> 
#> $kel.all$formalsmap
#> $kel.all$formalsmap$mrt
#> [1] "mrt.all"
#> 
#> 
#> $kel.all$depends
#> [1] "mrt.all"
#> 
#> $kel.all$datatype
#> [1] "interval"
#> 
#> $kel.all$pptestcd_cdisc
#> [1] "kel.all"
#> 
#> $kel.all$pptest_cdisc
#> [1] "Elimination rate (as calculated from the MRTall)"
#> 
#> 
#> $kel.int.all
#> $kel.int.all$FUN
#> [1] "pk.calc.kel"
#> 
#> $kel.int.all$values
#> [1] FALSE  TRUE
#> 
#> $kel.int.all$unit_type
#> [1] "inverse_time"
#> 
#> $kel.int.all$pretty_name
#> [1] "Kel (based on AUCint.all)"
#> 
#> $kel.int.all$desc
#> [1] "Elimination rate (as calculated from the MRTint.all)"
#> 
#> $kel.int.all$sparse
#> [1] FALSE
#> 
#> $kel.int.all$formalsmap
#> $kel.int.all$formalsmap$mrt
#> [1] "mrt.int.all"
#> 
#> 
#> $kel.int.all$depends
#> [1] "mrt.int.all"
#> 
#> $kel.int.all$datatype
#> [1] "interval"
#> 
#> $kel.int.all$pptestcd_cdisc
#> [1] "kel.int.all"
#> 
#> $kel.int.all$pptest_cdisc
#> [1] "Elimination rate (as calculated from the MRTint.all)"
#> 
#> 
#> $kel.int.last
#> $kel.int.last$FUN
#> [1] "pk.calc.kel"
#> 
#> $kel.int.last$values
#> [1] FALSE  TRUE
#> 
#> $kel.int.last$unit_type
#> [1] "inverse_time"
#> 
#> $kel.int.last$pretty_name
#> [1] "Kel (based on AUCint.last)"
#> 
#> $kel.int.last$desc
#> [1] "Elimination rate (as calculated from the MRTint.last)"
#> 
#> $kel.int.last$sparse
#> [1] FALSE
#> 
#> $kel.int.last$formalsmap
#> $kel.int.last$formalsmap$mrt
#> [1] "mrt.int.last"
#> 
#> 
#> $kel.int.last$depends
#> [1] "mrt.int.last"
#> 
#> $kel.int.last$datatype
#> [1] "interval"
#> 
#> $kel.int.last$pptestcd_cdisc
#> [1] "kel.int.last"
#> 
#> $kel.int.last$pptest_cdisc
#> [1] "Elimination rate (as calculated from the MRTint.last)"
#> 
#> 
#> $cl.iv.all
#> $cl.iv.all$FUN
#> [1] "pk.calc.cl"
#> 
#> $cl.iv.all$values
#> [1] FALSE  TRUE
#> 
#> $cl.iv.all$unit_type
#> [1] "clearance"
#> 
#> $cl.iv.all$pretty_name
#> [1] "CL (for IV dosing,  based on AUCall)"
#> 
#> $cl.iv.all$desc
#> [1] "Clearance for intravenous dosing calculated with AUCall"
#> 
#> $cl.iv.all$sparse
#> [1] FALSE
#> 
#> $cl.iv.all$formalsmap
#> $cl.iv.all$formalsmap$auc
#> [1] "aucivall"
#> 
#> 
#> $cl.iv.all$depends
#> [1] "aucivall"
#> 
#> $cl.iv.all$datatype
#> [1] "interval"
#> 
#> $cl.iv.all$pptestcd_cdisc
#> [1] "cl.iv.all"
#> 
#> $cl.iv.all$pptest_cdisc
#> [1] "Clearance for intravenous dosing calculated with AUCall"
#> 
#> 
#> $cl.iv.last
#> $cl.iv.last$FUN
#> [1] "pk.calc.cl"
#> 
#> $cl.iv.last$values
#> [1] FALSE  TRUE
#> 
#> $cl.iv.last$unit_type
#> [1] "clearance"
#> 
#> $cl.iv.last$pretty_name
#> [1] "CL (for IV dosing,  based on AUClast)"
#> 
#> $cl.iv.last$desc
#> [1] "Clearance for intravenous dosing calculated with AUClast"
#> 
#> $cl.iv.last$sparse
#> [1] FALSE
#> 
#> $cl.iv.last$formalsmap
#> $cl.iv.last$formalsmap$auc
#> [1] "aucivlast"
#> 
#> 
#> $cl.iv.last$depends
#> [1] "aucivlast"
#> 
#> $cl.iv.last$datatype
#> [1] "interval"
#> 
#> $cl.iv.last$pptestcd_cdisc
#> [1] "cl.iv.last"
#> 
#> $cl.iv.last$pptest_cdisc
#> [1] "Clearance for intravenous dosing calculated with AUClast"
#> 
#> 
#> $cl.ivint.all
#> $cl.ivint.all$FUN
#> [1] "pk.calc.cl"
#> 
#> $cl.ivint.all$values
#> [1] FALSE  TRUE
#> 
#> $cl.ivint.all$unit_type
#> [1] "clearance"
#> 
#> $cl.ivint.all$pretty_name
#> [1] "CL (IV dose interval, based on AUCint.all)"
#> 
#> $cl.ivint.all$desc
#> [1] "Clearance for intravenous dosing calculated with interval AUCint.all"
#> 
#> $cl.ivint.all$sparse
#> [1] FALSE
#> 
#> $cl.ivint.all$formalsmap
#> $cl.ivint.all$formalsmap$auc
#> [1] "aucivint.all"
#> 
#> 
#> $cl.ivint.all$depends
#> [1] "aucivint.all"
#> 
#> $cl.ivint.all$datatype
#> [1] "interval"
#> 
#> $cl.ivint.all$pptestcd_cdisc
#> [1] "cl.ivint.all"
#> 
#> $cl.ivint.all$pptest_cdisc
#> [1] "Clearance for intravenous dosing calculated with interval AUCint.all"
#> 
#> 
#> $cl.ivint.last
#> $cl.ivint.last$FUN
#> [1] "pk.calc.cl"
#> 
#> $cl.ivint.last$values
#> [1] FALSE  TRUE
#> 
#> $cl.ivint.last$unit_type
#> [1] "clearance"
#> 
#> $cl.ivint.last$pretty_name
#> [1] "CL (IV dose interval, based on AUCint.last)"
#> 
#> $cl.ivint.last$desc
#> [1] "Clearance for intravenous dosing calculated with interval AUCint.last"
#> 
#> $cl.ivint.last$sparse
#> [1] FALSE
#> 
#> $cl.ivint.last$formalsmap
#> $cl.ivint.last$formalsmap$auc
#> [1] "aucivint.last"
#> 
#> 
#> $cl.ivint.last$depends
#> [1] "aucivint.last"
#> 
#> $cl.ivint.last$datatype
#> [1] "interval"
#> 
#> $cl.ivint.last$pptestcd_cdisc
#> [1] "cl.ivint.last"
#> 
#> $cl.ivint.last$pptest_cdisc
#> [1] "Clearance for intravenous dosing calculated with interval AUCint.last"
#> 
#> 
#> $cl.sparse.last
#> $cl.sparse.last$FUN
#> [1] "pk.calc.cl"
#> 
#> $cl.sparse.last$values
#> [1] FALSE  TRUE
#> 
#> $cl.sparse.last$unit_type
#> [1] "clearance"
#> 
#> $cl.sparse.last$pretty_name
#> [1] "CL (for sparse data, based on AUClast)"
#> 
#> $cl.sparse.last$desc
#> [1] "Clearance from sparse sampling calculated with population AUClast"
#> 
#> $cl.sparse.last$sparse
#> [1] TRUE
#> 
#> $cl.sparse.last$formalsmap
#> $cl.sparse.last$formalsmap$auc
#> [1] "sparse_auclast"
#> 
#> 
#> $cl.sparse.last$depends
#> [1] "sparse_auclast"
#> 
#> $cl.sparse.last$datatype
#> [1] "interval"
#> 
#> $cl.sparse.last$pptestcd_cdisc
#> [1] "cl.sparse.last"
#> 
#> $cl.sparse.last$pptest_cdisc
#> [1] "Clearance from sparse sampling calculated with population AUClast"
#> 
#> 
#> $mrt.sparse.last
#> $mrt.sparse.last$FUN
#> [1] "pk.calc.mrt"
#> 
#> $mrt.sparse.last$values
#> [1] FALSE  TRUE
#> 
#> $mrt.sparse.last$unit_type
#> [1] "time"
#> 
#> $mrt.sparse.last$pretty_name
#> [1] "MRT (for sparse data, based on AUClast)"
#> 
#> $mrt.sparse.last$desc
#> [1] "Mean residence time from sparse sampling"
#> 
#> $mrt.sparse.last$sparse
#> [1] TRUE
#> 
#> $mrt.sparse.last$formalsmap
#> $mrt.sparse.last$formalsmap$auc
#> [1] "sparse_auclast"
#> 
#> $mrt.sparse.last$formalsmap$aumc
#> [1] "sparse_aumclast"
#> 
#> 
#> $mrt.sparse.last$depends
#> [1] "sparse_auclast"  "sparse_aumclast"
#> 
#> $mrt.sparse.last$datatype
#> [1] "interval"
#> 
#> $mrt.sparse.last$pptestcd_cdisc
#> [1] "mrt.sparse.last"
#> 
#> $mrt.sparse.last$pptest_cdisc
#> [1] "Mean residence time from sparse sampling"
#> 
#> 
#> $mrt.iv.all
#> $mrt.iv.all$FUN
#> [1] "pk.calc.mrt.iv"
#> 
#> $mrt.iv.all$values
#> [1] FALSE  TRUE
#> 
#> $mrt.iv.all$unit_type
#> [1] "time"
#> 
#> $mrt.iv.all$pretty_name
#> [1] "MRT (for IV dosing, based on AUCall)"
#> 
#> $mrt.iv.all$desc
#> [1] "Mean residence time for IV dosing calculated with AUCall/AUMCall"
#> 
#> $mrt.iv.all$sparse
#> [1] FALSE
#> 
#> $mrt.iv.all$formalsmap
#> $mrt.iv.all$formalsmap$auc
#> [1] "aucivall"
#> 
#> $mrt.iv.all$formalsmap$aumc
#> [1] "aumcivall"
#> 
#> 
#> $mrt.iv.all$depends
#> [1] "aucivall"  "aumcivall"
#> 
#> $mrt.iv.all$datatype
#> [1] "interval"
#> 
#> $mrt.iv.all$pptestcd_cdisc
#> [1] "mrt.iv.all"
#> 
#> $mrt.iv.all$pptest_cdisc
#> [1] "Mean residence time for IV dosing calculated with AUCall/AUMCall"
#> 
#> 
#> $mrt.ivint.all
#> $mrt.ivint.all$FUN
#> [1] "pk.calc.mrt.iv"
#> 
#> $mrt.ivint.all$values
#> [1] FALSE  TRUE
#> 
#> $mrt.ivint.all$unit_type
#> [1] "time"
#> 
#> $mrt.ivint.all$pretty_name
#> [1] "MRT (IV dose interval, based on AUCint.all)"
#> 
#> $mrt.ivint.all$desc
#> [1] "Mean residence time for IV interval calculated with AUCint.all/AUMCint.all"
#> 
#> $mrt.ivint.all$sparse
#> [1] FALSE
#> 
#> $mrt.ivint.all$formalsmap
#> $mrt.ivint.all$formalsmap$auc
#> [1] "aucivint.all"
#> 
#> $mrt.ivint.all$formalsmap$aumc
#> [1] "aumcivint.all"
#> 
#> 
#> $mrt.ivint.all$depends
#> [1] "aucivint.all"  "aumcivint.all"
#> 
#> $mrt.ivint.all$datatype
#> [1] "interval"
#> 
#> $mrt.ivint.all$pptestcd_cdisc
#> [1] "mrt.ivint.all"
#> 
#> $mrt.ivint.all$pptest_cdisc
#> [1] "Mean residence time for IV interval calculated with AUCint.all/AUMCint.all"
#> 
#> 
#> $mrt.ivint.last
#> $mrt.ivint.last$FUN
#> [1] "pk.calc.mrt.iv"
#> 
#> $mrt.ivint.last$values
#> [1] FALSE  TRUE
#> 
#> $mrt.ivint.last$unit_type
#> [1] "time"
#> 
#> $mrt.ivint.last$pretty_name
#> [1] "MRT (IV dose interval, based on AUCint.last)"
#> 
#> $mrt.ivint.last$desc
#> [1] "Mean residence time for IV interval calculated with AUCint.last/AUMCint.last"
#> 
#> $mrt.ivint.last$sparse
#> [1] FALSE
#> 
#> $mrt.ivint.last$formalsmap
#> $mrt.ivint.last$formalsmap$auc
#> [1] "aucivint.last"
#> 
#> $mrt.ivint.last$formalsmap$aumc
#> [1] "aumcivint.last"
#> 
#> 
#> $mrt.ivint.last$depends
#> [1] "aucivint.last"  "aumcivint.last"
#> 
#> $mrt.ivint.last$datatype
#> [1] "interval"
#> 
#> $mrt.ivint.last$pptestcd_cdisc
#> [1] "mrt.ivint.last"
#> 
#> $mrt.ivint.last$pptest_cdisc
#> [1] "Mean residence time for IV interval calculated with AUCint.last/AUMCint.last"
#> 
#> 
#> $vz.all
#> $vz.all$FUN
#> [1] "pk.calc.vz"
#> 
#> $vz.all$values
#> [1] FALSE  TRUE
#> 
#> $vz.all$unit_type
#> [1] "volume"
#> 
#> $vz.all$pretty_name
#> [1] "Vz (based on AUCall)"
#> 
#> $vz.all$desc
#> [1] "Terminal volume of distribution calculated with AUCall-based CL"
#> 
#> $vz.all$sparse
#> [1] FALSE
#> 
#> $vz.all$formalsmap
#> $vz.all$formalsmap$cl
#> [1] "cl.all"
#> 
#> 
#> $vz.all$depends
#> [1] "cl.all"   "lambda.z"
#> 
#> $vz.all$datatype
#> [1] "interval"
#> 
#> $vz.all$pptestcd_cdisc
#> [1] "vz.all"
#> 
#> $vz.all$pptest_cdisc
#> [1] "Terminal volume of distribution calculated with AUCall-based CL"
#> 
#> 
#> $vz.int.all
#> $vz.int.all$FUN
#> [1] "pk.calc.vz"
#> 
#> $vz.int.all$values
#> [1] FALSE  TRUE
#> 
#> $vz.int.all$unit_type
#> [1] "volume"
#> 
#> $vz.int.all$pretty_name
#> [1] "Vz (based on AUCint.all)"
#> 
#> $vz.int.all$desc
#> [1] "Terminal volume of distribution using interval AUCint.all"
#> 
#> $vz.int.all$sparse
#> [1] FALSE
#> 
#> $vz.int.all$formalsmap
#> $vz.int.all$formalsmap$cl
#> [1] "cl.int.all"
#> 
#> 
#> $vz.int.all$depends
#> [1] "cl.int.all" "lambda.z"  
#> 
#> $vz.int.all$datatype
#> [1] "interval"
#> 
#> $vz.int.all$pptestcd_cdisc
#> [1] "vz.int.all"
#> 
#> $vz.int.all$pptest_cdisc
#> [1] "Terminal volume of distribution using interval AUCint.all"
#> 
#> 
#> $vz.int.last
#> $vz.int.last$FUN
#> [1] "pk.calc.vz"
#> 
#> $vz.int.last$values
#> [1] FALSE  TRUE
#> 
#> $vz.int.last$unit_type
#> [1] "volume"
#> 
#> $vz.int.last$pretty_name
#> [1] "Vz (based on AUCint.last)"
#> 
#> $vz.int.last$desc
#> [1] "Terminal volume of distribution using interval AUCint.last"
#> 
#> $vz.int.last$sparse
#> [1] FALSE
#> 
#> $vz.int.last$formalsmap
#> $vz.int.last$formalsmap$cl
#> [1] "cl.int.last"
#> 
#> 
#> $vz.int.last$depends
#> [1] "cl.int.last" "lambda.z"   
#> 
#> $vz.int.last$datatype
#> [1] "interval"
#> 
#> $vz.int.last$pptestcd_cdisc
#> [1] "vz.int.last"
#> 
#> $vz.int.last$pptest_cdisc
#> [1] "Terminal volume of distribution using interval AUCint.last"
#> 
#> 
#> $vz.iv.all
#> $vz.iv.all$FUN
#> [1] "pk.calc.vz"
#> 
#> $vz.iv.all$values
#> [1] FALSE  TRUE
#> 
#> $vz.iv.all$unit_type
#> [1] "volume"
#> 
#> $vz.iv.all$pretty_name
#> [1] "Vz (for IV dosing,  based on AUCall)"
#> 
#> $vz.iv.all$desc
#> [1] "Terminal volume of distribution for IV dosing using AUCall"
#> 
#> $vz.iv.all$sparse
#> [1] FALSE
#> 
#> $vz.iv.all$formalsmap
#> $vz.iv.all$formalsmap$cl
#> [1] "cl.iv.all"
#> 
#> 
#> $vz.iv.all$depends
#> [1] "cl.iv.all" "lambda.z" 
#> 
#> $vz.iv.all$datatype
#> [1] "interval"
#> 
#> $vz.iv.all$pptestcd_cdisc
#> [1] "vz.iv.all"
#> 
#> $vz.iv.all$pptest_cdisc
#> [1] "Terminal volume of distribution for IV dosing using AUCall"
#> 
#> 
#> $vz.iv.last
#> $vz.iv.last$FUN
#> [1] "pk.calc.vz"
#> 
#> $vz.iv.last$values
#> [1] FALSE  TRUE
#> 
#> $vz.iv.last$unit_type
#> [1] "volume"
#> 
#> $vz.iv.last$pretty_name
#> [1] "Vz (for IV dosing,  based on AUClast)"
#> 
#> $vz.iv.last$desc
#> [1] "Terminal volume of distribution for IV dosing using AUClast"
#> 
#> $vz.iv.last$sparse
#> [1] FALSE
#> 
#> $vz.iv.last$formalsmap
#> $vz.iv.last$formalsmap$cl
#> [1] "cl.iv.last"
#> 
#> 
#> $vz.iv.last$depends
#> [1] "cl.iv.last" "lambda.z"  
#> 
#> $vz.iv.last$datatype
#> [1] "interval"
#> 
#> $vz.iv.last$pptestcd_cdisc
#> [1] "vz.iv.last"
#> 
#> $vz.iv.last$pptest_cdisc
#> [1] "Terminal volume of distribution for IV dosing using AUClast"
#> 
#> 
#> $vz.ivint.all
#> $vz.ivint.all$FUN
#> [1] "pk.calc.vz"
#> 
#> $vz.ivint.all$values
#> [1] FALSE  TRUE
#> 
#> $vz.ivint.all$unit_type
#> [1] "volume"
#> 
#> $vz.ivint.all$pretty_name
#> [1] "Vz (IV dose interval, based on AUCint.all)"
#> 
#> $vz.ivint.all$desc
#> [1] "Terminal volume of distribution for IV interval using AUCint.all"
#> 
#> $vz.ivint.all$sparse
#> [1] FALSE
#> 
#> $vz.ivint.all$formalsmap
#> $vz.ivint.all$formalsmap$cl
#> [1] "cl.ivint.all"
#> 
#> 
#> $vz.ivint.all$depends
#> [1] "cl.ivint.all" "lambda.z"    
#> 
#> $vz.ivint.all$datatype
#> [1] "interval"
#> 
#> $vz.ivint.all$pptestcd_cdisc
#> [1] "vz.ivint.all"
#> 
#> $vz.ivint.all$pptest_cdisc
#> [1] "Terminal volume of distribution for IV interval using AUCint.all"
#> 
#> 
#> $vz.ivint.last
#> $vz.ivint.last$FUN
#> [1] "pk.calc.vz"
#> 
#> $vz.ivint.last$values
#> [1] FALSE  TRUE
#> 
#> $vz.ivint.last$unit_type
#> [1] "volume"
#> 
#> $vz.ivint.last$pretty_name
#> [1] "Vz (IV dose interval, based on AUCint.last)"
#> 
#> $vz.ivint.last$desc
#> [1] "Terminal volume of distribution for IV interval using AUCint.last"
#> 
#> $vz.ivint.last$sparse
#> [1] FALSE
#> 
#> $vz.ivint.last$formalsmap
#> $vz.ivint.last$formalsmap$cl
#> [1] "cl.ivint.last"
#> 
#> 
#> $vz.ivint.last$depends
#> [1] "cl.ivint.last" "lambda.z"     
#> 
#> $vz.ivint.last$datatype
#> [1] "interval"
#> 
#> $vz.ivint.last$pptestcd_cdisc
#> [1] "vz.ivint.last"
#> 
#> $vz.ivint.last$pptest_cdisc
#> [1] "Terminal volume of distribution for IV interval using AUCint.last"
#> 
#> 
#> $vz.last
#> $vz.last$FUN
#> [1] "pk.calc.vz"
#> 
#> $vz.last$values
#> [1] FALSE  TRUE
#> 
#> $vz.last$unit_type
#> [1] "volume"
#> 
#> $vz.last$pretty_name
#> [1] "Vz (based on AUClast)"
#> 
#> $vz.last$desc
#> [1] "Terminal volume of distribution calculated with AUClast-based CL"
#> 
#> $vz.last$sparse
#> [1] FALSE
#> 
#> $vz.last$formalsmap
#> $vz.last$formalsmap$cl
#> [1] "cl.last"
#> 
#> 
#> $vz.last$depends
#> [1] "cl.last"  "lambda.z"
#> 
#> $vz.last$datatype
#> [1] "interval"
#> 
#> $vz.last$pptestcd_cdisc
#> [1] "vz.last"
#> 
#> $vz.last$pptest_cdisc
#> [1] "Terminal volume of distribution calculated with AUClast-based CL"
#> 
#> 
#> $vss.iv.all
#> $vss.iv.all$FUN
#> [1] "pk.calc.vss"
#> 
#> $vss.iv.all$values
#> [1] FALSE  TRUE
#> 
#> $vss.iv.all$unit_type
#> [1] "volume"
#> 
#> $vss.iv.all$pretty_name
#> [1] "Vss (for IV dosing,  based on AUCall)"
#> 
#> $vss.iv.all$desc
#> [1] "Steady-state volume of distribution for IV dosing using AUCall"
#> 
#> $vss.iv.all$sparse
#> [1] FALSE
#> 
#> $vss.iv.all$formalsmap
#> $vss.iv.all$formalsmap$cl
#> [1] "cl.iv.all"
#> 
#> $vss.iv.all$formalsmap$mrt
#> [1] "mrt.iv.all"
#> 
#> 
#> $vss.iv.all$depends
#> [1] "cl.iv.all"  "mrt.iv.all"
#> 
#> $vss.iv.all$datatype
#> [1] "interval"
#> 
#> $vss.iv.all$pptestcd_cdisc
#> [1] "vss.iv.all"
#> 
#> $vss.iv.all$pptest_cdisc
#> [1] "Steady-state volume of distribution for IV dosing using AUCall"
#> 
#> 
#> $vss.ivint.all
#> $vss.ivint.all$FUN
#> [1] "pk.calc.vss"
#> 
#> $vss.ivint.all$values
#> [1] FALSE  TRUE
#> 
#> $vss.ivint.all$unit_type
#> [1] "volume"
#> 
#> $vss.ivint.all$pretty_name
#> [1] "Vss (IV dose interval, based on AUCint.all)"
#> 
#> $vss.ivint.all$desc
#> [1] "Steady-state volume of distribution for IV interval using AUCint.all"
#> 
#> $vss.ivint.all$sparse
#> [1] FALSE
#> 
#> $vss.ivint.all$formalsmap
#> $vss.ivint.all$formalsmap$cl
#> [1] "cl.ivint.all"
#> 
#> $vss.ivint.all$formalsmap$mrt
#> [1] "mrt.ivint.all"
#> 
#> 
#> $vss.ivint.all$depends
#> [1] "cl.ivint.all"  "mrt.ivint.all"
#> 
#> $vss.ivint.all$datatype
#> [1] "interval"
#> 
#> $vss.ivint.all$pptestcd_cdisc
#> [1] "vss.ivint.all"
#> 
#> $vss.ivint.all$pptest_cdisc
#> [1] "Steady-state volume of distribution for IV interval using AUCint.all"
#> 
#> 
#> $vss.ivint.last
#> $vss.ivint.last$FUN
#> [1] "pk.calc.vss"
#> 
#> $vss.ivint.last$values
#> [1] FALSE  TRUE
#> 
#> $vss.ivint.last$unit_type
#> [1] "volume"
#> 
#> $vss.ivint.last$pretty_name
#> [1] "Vss (IV dose interval, based on AUCint.last)"
#> 
#> $vss.ivint.last$desc
#> [1] "Steady-state volume of distribution for IV interval using AUCint.last"
#> 
#> $vss.ivint.last$sparse
#> [1] FALSE
#> 
#> $vss.ivint.last$formalsmap
#> $vss.ivint.last$formalsmap$cl
#> [1] "cl.ivint.last"
#> 
#> $vss.ivint.last$formalsmap$mrt
#> [1] "mrt.ivint.last"
#> 
#> 
#> $vss.ivint.last$depends
#> [1] "cl.ivint.last"  "mrt.ivint.last"
#> 
#> $vss.ivint.last$datatype
#> [1] "interval"
#> 
#> $vss.ivint.last$pptestcd_cdisc
#> [1] "vss.ivint.last"
#> 
#> $vss.ivint.last$pptest_cdisc
#> [1] "Steady-state volume of distribution for IV interval using AUCint.last"
#> 
#> 
#> $vss.sparse.last
#> $vss.sparse.last$FUN
#> [1] "pk.calc.vss"
#> 
#> $vss.sparse.last$values
#> [1] FALSE  TRUE
#> 
#> $vss.sparse.last$unit_type
#> [1] "volume"
#> 
#> $vss.sparse.last$pretty_name
#> [1] "Vss (for sparse data, based on AUClast)"
#> 
#> $vss.sparse.last$desc
#> [1] "Steady-state volume of distribution from sparse sampling"
#> 
#> $vss.sparse.last$sparse
#> [1] TRUE
#> 
#> $vss.sparse.last$formalsmap
#> $vss.sparse.last$formalsmap$cl
#> [1] "cl.sparse.last"
#> 
#> $vss.sparse.last$formalsmap$mrt
#> [1] "mrt.sparse.last"
#> 
#> 
#> $vss.sparse.last$depends
#> [1] "cl.sparse.last"  "mrt.sparse.last"
#> 
#> $vss.sparse.last$datatype
#> [1] "interval"
#> 
#> $vss.sparse.last$pptestcd_cdisc
#> [1] "vss.sparse.last"
#> 
#> $vss.sparse.last$pptest_cdisc
#> [1] "Steady-state volume of distribution from sparse sampling"
#> 
#> 
#> $aucinf.obs
#> $aucinf.obs$FUN
#> [1] "pk.calc.auc.inf.obs"
#> 
#> $aucinf.obs$values
#> [1] FALSE  TRUE
#> 
#> $aucinf.obs$unit_type
#> [1] "auc"
#> 
#> $aucinf.obs$pretty_name
#> [1] "AUCinf,obs"
#> 
#> $aucinf.obs$desc
#> [1] "The area under the concentration time curve from the beginning of the interval to infinity with extrapolation to infinity from the observed Clast"
#> 
#> $aucinf.obs$sparse
#> [1] FALSE
#> 
#> $aucinf.obs$formalsmap
#> list()
#> 
#> $aucinf.obs$depends
#> [1] "lambda.z"  "clast.obs"
#> 
#> $aucinf.obs$datatype
#> [1] "interval"
#> 
#> $aucinf.obs$pptestcd_cdisc
#> [1] "AUCIFO"
#> 
#> $aucinf.obs$pptest_cdisc
#> [1] "AUC Infinity Obs"
#> 
#> 
#> $aucinf.pred
#> $aucinf.pred$FUN
#> [1] "pk.calc.auc.inf.pred"
#> 
#> $aucinf.pred$values
#> [1] FALSE  TRUE
#> 
#> $aucinf.pred$unit_type
#> [1] "auc"
#> 
#> $aucinf.pred$pretty_name
#> [1] "AUCinf,pred"
#> 
#> $aucinf.pred$desc
#> [1] "The area under the concentration time curve from the beginning of the interval to infinity with extrapolation to infinity from the predicted Clast"
#> 
#> $aucinf.pred$sparse
#> [1] FALSE
#> 
#> $aucinf.pred$formalsmap
#> list()
#> 
#> $aucinf.pred$depends
#> [1] "lambda.z"   "clast.pred"
#> 
#> $aucinf.pred$datatype
#> [1] "interval"
#> 
#> $aucinf.pred$pptestcd_cdisc
#> [1] "AUCIFP"
#> 
#> $aucinf.pred$pptest_cdisc
#> [1] "AUC Infinity Pred"
#> 
#> 
#> $aumcinf.obs
#> $aumcinf.obs$FUN
#> [1] "pk.calc.aumc.inf.obs"
#> 
#> $aumcinf.obs$values
#> [1] FALSE  TRUE
#> 
#> $aumcinf.obs$unit_type
#> [1] "aumc"
#> 
#> $aumcinf.obs$pretty_name
#> [1] "AUMC,inf,obs"
#> 
#> $aumcinf.obs$desc
#> [1] "The area under the concentration time moment curve from the beginning of the interval to infinity with extrapolation to infinity from the observed Clast"
#> 
#> $aumcinf.obs$sparse
#> [1] FALSE
#> 
#> $aumcinf.obs$formalsmap
#> list()
#> 
#> $aumcinf.obs$depends
#> [1] "lambda.z"  "clast.obs"
#> 
#> $aumcinf.obs$datatype
#> [1] "interval"
#> 
#> $aumcinf.obs$pptestcd_cdisc
#> [1] "AUMCIFO"
#> 
#> $aumcinf.obs$pptest_cdisc
#> [1] "AUMC Infinity Obs"
#> 
#> 
#> $aumcinf.pred
#> $aumcinf.pred$FUN
#> [1] "pk.calc.aumc.inf.pred"
#> 
#> $aumcinf.pred$values
#> [1] FALSE  TRUE
#> 
#> $aumcinf.pred$unit_type
#> [1] "aumc"
#> 
#> $aumcinf.pred$pretty_name
#> [1] "AUMC,inf,pred"
#> 
#> $aumcinf.pred$desc
#> [1] "The area under the concentration time moment curve from the beginning of the interval to infinity with extrapolation to infinity from the predicted Clast"
#> 
#> $aumcinf.pred$sparse
#> [1] FALSE
#> 
#> $aumcinf.pred$formalsmap
#> list()
#> 
#> $aumcinf.pred$depends
#> [1] "lambda.z"   "clast.pred"
#> 
#> $aumcinf.pred$datatype
#> [1] "interval"
#> 
#> $aumcinf.pred$pptestcd_cdisc
#> [1] "AUMCIFP"
#> 
#> $aumcinf.pred$pptest_cdisc
#> [1] "AUMC Infinity Pred"
#> 
#> 
#> $aucint.inf.obs
#> $aucint.inf.obs$FUN
#> [1] "pk.calc.aucint.inf.obs"
#> 
#> $aucint.inf.obs$values
#> [1] FALSE  TRUE
#> 
#> $aucint.inf.obs$unit_type
#> [1] "auc"
#> 
#> $aucint.inf.obs$pretty_name
#> [1] "AUCint (based on AUCinf,obs extrapolation)"
#> 
#> $aucint.inf.obs$desc
#> [1] "The area under the concentration time curve in the interval extrapolating from Tlast to infinity with zeros (matching AUClast)"
#> 
#> $aucint.inf.obs$sparse
#> [1] FALSE
#> 
#> $aucint.inf.obs$formalsmap
#> $aucint.inf.obs$formalsmap$conc
#> [1] "conc.group"
#> 
#> $aucint.inf.obs$formalsmap$time
#> [1] "time.group"
#> 
#> $aucint.inf.obs$formalsmap$time.dose
#> NULL
#> 
#> 
#> $aucint.inf.obs$depends
#> [1] "lambda.z"  "clast.obs"
#> 
#> $aucint.inf.obs$datatype
#> [1] "interval"
#> 
#> $aucint.inf.obs$pptestcd_cdisc
#> [1] "AUCINTIS"
#> 
#> $aucint.inf.obs$pptest_cdisc
#> [1] "AUCint (based on AUCinf,obs extrapolation)"
#> 
#> 
#> $aucint.inf.obs.dose
#> $aucint.inf.obs.dose$FUN
#> [1] "pk.calc.aucint.inf.obs"
#> 
#> $aucint.inf.obs.dose$values
#> [1] FALSE  TRUE
#> 
#> $aucint.inf.obs.dose$unit_type
#> [1] "auc"
#> 
#> $aucint.inf.obs.dose$pretty_name
#> [1] "AUCint (based on AUCinf,obs extrapolation, dose-aware)"
#> 
#> $aucint.inf.obs.dose$desc
#> [1] "The area under the concentration time curve in the interval extrapolating from Tlast to infinity with zeros (matching AUClast) with dose-aware interpolation/extrapolation of concentrations"
#> 
#> $aucint.inf.obs.dose$sparse
#> [1] FALSE
#> 
#> $aucint.inf.obs.dose$formalsmap
#> $aucint.inf.obs.dose$formalsmap$conc
#> [1] "conc.group"
#> 
#> $aucint.inf.obs.dose$formalsmap$time
#> [1] "time.group"
#> 
#> $aucint.inf.obs.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#> 
#> 
#> $aucint.inf.obs.dose$depends
#> [1] "lambda.z"  "clast.obs"
#> 
#> $aucint.inf.obs.dose$datatype
#> [1] "interval"
#> 
#> $aucint.inf.obs.dose$pptestcd_cdisc
#> [1] "AUCINTID"
#> 
#> $aucint.inf.obs.dose$pptest_cdisc
#> [1] "AUCint (based on AUCinf,obs extrapolation, dose-aware)"
#> 
#> 
#> $aucint.inf.pred
#> $aucint.inf.pred$FUN
#> [1] "pk.calc.aucint.inf.pred"
#> 
#> $aucint.inf.pred$values
#> [1] FALSE  TRUE
#> 
#> $aucint.inf.pred$unit_type
#> [1] "auc"
#> 
#> $aucint.inf.pred$pretty_name
#> [1] "AUCint (based on AUCinf,pred extrapolation)"
#> 
#> $aucint.inf.pred$desc
#> [1] "The area under the concentration time curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUCall)"
#> 
#> $aucint.inf.pred$sparse
#> [1] FALSE
#> 
#> $aucint.inf.pred$formalsmap
#> $aucint.inf.pred$formalsmap$conc
#> [1] "conc.group"
#> 
#> $aucint.inf.pred$formalsmap$time
#> [1] "time.group"
#> 
#> $aucint.inf.pred$formalsmap$time.dose
#> NULL
#> 
#> 
#> $aucint.inf.pred$depends
#> [1] "lambda.z"   "clast.pred"
#> 
#> $aucint.inf.pred$datatype
#> [1] "interval"
#> 
#> $aucint.inf.pred$pptestcd_cdisc
#> [1] "AUCINTIP"
#> 
#> $aucint.inf.pred$pptest_cdisc
#> [1] "AUCint (based on AUCinf,pred extrapolation)"
#> 
#> 
#> $aucint.inf.pred.dose
#> $aucint.inf.pred.dose$FUN
#> [1] "pk.calc.aucint.inf.pred"
#> 
#> $aucint.inf.pred.dose$values
#> [1] FALSE  TRUE
#> 
#> $aucint.inf.pred.dose$unit_type
#> [1] "auc"
#> 
#> $aucint.inf.pred.dose$pretty_name
#> [1] "AUCint (based on AUCinf,pred extrapolation, dose-aware)"
#> 
#> $aucint.inf.pred.dose$desc
#> [1] "The area under the concentration time curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUCall) with dose-aware interpolation/extrapolation of concentrations"
#> 
#> $aucint.inf.pred.dose$sparse
#> [1] FALSE
#> 
#> $aucint.inf.pred.dose$formalsmap
#> $aucint.inf.pred.dose$formalsmap$conc
#> [1] "conc.group"
#> 
#> $aucint.inf.pred.dose$formalsmap$time
#> [1] "time.group"
#> 
#> $aucint.inf.pred.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#> 
#> 
#> $aucint.inf.pred.dose$depends
#> [1] "lambda.z"   "clast.pred"
#> 
#> $aucint.inf.pred.dose$datatype
#> [1] "interval"
#> 
#> $aucint.inf.pred.dose$pptestcd_cdisc
#> [1] "AUCINTPD"
#> 
#> $aucint.inf.pred.dose$pptest_cdisc
#> [1] "AUCint (based on AUCinf,pred extrapolation, dose-aware)"
#> 
#> 
#> $aumcint.inf.obs
#> $aumcint.inf.obs$FUN
#> [1] "pk.calc.aumcint.inf.obs"
#> 
#> $aumcint.inf.obs$values
#> [1] FALSE  TRUE
#> 
#> $aumcint.inf.obs$unit_type
#> [1] "aumc"
#> 
#> $aumcint.inf.obs$pretty_name
#> [1] "AUMCint (based on AUMCinf,obs extrapolation)"
#> 
#> $aumcint.inf.obs$desc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with zeros (matching AUMClast)"
#> 
#> $aumcint.inf.obs$sparse
#> [1] FALSE
#> 
#> $aumcint.inf.obs$formalsmap
#> $aumcint.inf.obs$formalsmap$conc
#> [1] "conc.group"
#> 
#> $aumcint.inf.obs$formalsmap$time
#> [1] "time.group"
#> 
#> $aumcint.inf.obs$formalsmap$time.dose
#> NULL
#> 
#> 
#> $aumcint.inf.obs$depends
#> [1] "lambda.z"  "clast.obs"
#> 
#> $aumcint.inf.obs$datatype
#> [1] "interval"
#> 
#> $aumcint.inf.obs$pptestcd_cdisc
#> [1] "aumcint.inf.obs"
#> 
#> $aumcint.inf.obs$pptest_cdisc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with zeros (matching AUMClast)"
#> 
#> 
#> $aumcint.inf.obs.dose
#> $aumcint.inf.obs.dose$FUN
#> [1] "pk.calc.aumcint.inf.obs"
#> 
#> $aumcint.inf.obs.dose$values
#> [1] FALSE  TRUE
#> 
#> $aumcint.inf.obs.dose$unit_type
#> [1] "aumc"
#> 
#> $aumcint.inf.obs.dose$pretty_name
#> [1] "AUMCint (based on AUMCinf,obs extrapolation, dose-aware)"
#> 
#> $aumcint.inf.obs.dose$desc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with zeros (matching AUMClast) with dose-aware interpolation/extrapolation of concentrations"
#> 
#> $aumcint.inf.obs.dose$sparse
#> [1] FALSE
#> 
#> $aumcint.inf.obs.dose$formalsmap
#> $aumcint.inf.obs.dose$formalsmap$conc
#> [1] "conc.group"
#> 
#> $aumcint.inf.obs.dose$formalsmap$time
#> [1] "time.group"
#> 
#> $aumcint.inf.obs.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#> 
#> 
#> $aumcint.inf.obs.dose$depends
#> [1] "lambda.z"  "clast.obs"
#> 
#> $aumcint.inf.obs.dose$datatype
#> [1] "interval"
#> 
#> $aumcint.inf.obs.dose$pptestcd_cdisc
#> [1] "aumcint.inf.obs.dose"
#> 
#> $aumcint.inf.obs.dose$pptest_cdisc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with zeros (matching AUMClast) with dose-aware interpolation/extrapolation of concentrations"
#> 
#> 
#> $aumcint.inf.pred
#> $aumcint.inf.pred$FUN
#> [1] "pk.calc.aumcint.inf.pred"
#> 
#> $aumcint.inf.pred$values
#> [1] FALSE  TRUE
#> 
#> $aumcint.inf.pred$unit_type
#> [1] "aumc"
#> 
#> $aumcint.inf.pred$pretty_name
#> [1] "AUMCint (based on AUMCinf,pred extrapolation)"
#> 
#> $aumcint.inf.pred$desc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUMCall)"
#> 
#> $aumcint.inf.pred$sparse
#> [1] FALSE
#> 
#> $aumcint.inf.pred$formalsmap
#> $aumcint.inf.pred$formalsmap$conc
#> [1] "conc.group"
#> 
#> $aumcint.inf.pred$formalsmap$time
#> [1] "time.group"
#> 
#> $aumcint.inf.pred$formalsmap$time.dose
#> NULL
#> 
#> 
#> $aumcint.inf.pred$depends
#> [1] "lambda.z"   "clast.pred"
#> 
#> $aumcint.inf.pred$datatype
#> [1] "interval"
#> 
#> $aumcint.inf.pred$pptestcd_cdisc
#> [1] "aumcint.inf.pred"
#> 
#> $aumcint.inf.pred$pptest_cdisc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUMCall)"
#> 
#> 
#> $aumcint.inf.pred.dose
#> $aumcint.inf.pred.dose$FUN
#> [1] "pk.calc.aumcint.inf.pred"
#> 
#> $aumcint.inf.pred.dose$values
#> [1] FALSE  TRUE
#> 
#> $aumcint.inf.pred.dose$unit_type
#> [1] "aumc"
#> 
#> $aumcint.inf.pred.dose$pretty_name
#> [1] "AUMCint (based on AUMCinf,pred extrapolation, dose-aware)"
#> 
#> $aumcint.inf.pred.dose$desc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUMCall) with dose-aware interpolation/extrapolation of concentrations"
#> 
#> $aumcint.inf.pred.dose$sparse
#> [1] FALSE
#> 
#> $aumcint.inf.pred.dose$formalsmap
#> $aumcint.inf.pred.dose$formalsmap$conc
#> [1] "conc.group"
#> 
#> $aumcint.inf.pred.dose$formalsmap$time
#> [1] "time.group"
#> 
#> $aumcint.inf.pred.dose$formalsmap$time.dose
#> [1] "time.dose.group"
#> 
#> 
#> $aumcint.inf.pred.dose$depends
#> [1] "lambda.z"   "clast.pred"
#> 
#> $aumcint.inf.pred.dose$datatype
#> [1] "interval"
#> 
#> $aumcint.inf.pred.dose$pptestcd_cdisc
#> [1] "aumcint.inf.pred.dose"
#> 
#> $aumcint.inf.pred.dose$pptest_cdisc
#> [1] "The area under the moment curve in the interval extrapolating from Tlast to infinity with the triangle from Tlast to the next point and zero thereafter (matching AUMCall) with dose-aware interpolation/extrapolation of concentrations"
#> 
#> 
#> $aucivinf.obs
#> $aucivinf.obs$FUN
#> [1] "pk.calc.auciv"
#> 
#> $aucivinf.obs$values
#> [1] FALSE  TRUE
#> 
#> $aucivinf.obs$unit_type
#> [1] "auc"
#> 
#> $aucivinf.obs$pretty_name
#> [1] "AUCinf,obs (IV dosing)"
#> 
#> $aucivinf.obs$desc
#> [1] "The AUCinf,obs calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#> 
#> $aucivinf.obs$sparse
#> [1] FALSE
#> 
#> $aucivinf.obs$formalsmap
#> $aucivinf.obs$formalsmap$auc
#> [1] "aucinf.obs"
#> 
#> 
#> $aucivinf.obs$depends
#> [1] "aucinf.obs" "c0"        
#> 
#> $aucivinf.obs$datatype
#> [1] "interval"
#> 
#> $aucivinf.obs$pptestcd_cdisc
#> [1] "AUCIVIS"
#> 
#> $aucivinf.obs$pptest_cdisc
#> [1] "AUCinf,obs (IV dosing)"
#> 
#> 
#> $aucivinf.pred
#> $aucivinf.pred$FUN
#> [1] "pk.calc.auciv"
#> 
#> $aucivinf.pred$values
#> [1] FALSE  TRUE
#> 
#> $aucivinf.pred$unit_type
#> [1] "auc"
#> 
#> $aucivinf.pred$pretty_name
#> [1] "AUCinf,pred (IV dosing)"
#> 
#> $aucivinf.pred$desc
#> [1] "The AUCinf,pred calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#> 
#> $aucivinf.pred$sparse
#> [1] FALSE
#> 
#> $aucivinf.pred$formalsmap
#> $aucivinf.pred$formalsmap$auc
#> [1] "aucinf.pred"
#> 
#> 
#> $aucivinf.pred$depends
#> [1] "aucinf.pred" "c0"         
#> 
#> $aucivinf.pred$datatype
#> [1] "interval"
#> 
#> $aucivinf.pred$pptestcd_cdisc
#> [1] "AUCIVIP"
#> 
#> $aucivinf.pred$pptest_cdisc
#> [1] "AUCinf,pred (IV dosing)"
#> 
#> 
#> $aucivpbextinf.obs
#> $aucivpbextinf.obs$FUN
#> [1] "pk.calc.auciv_pbext"
#> 
#> $aucivpbextinf.obs$values
#> [1] FALSE  TRUE
#> 
#> $aucivpbextinf.obs$unit_type
#> [1] "%"
#> 
#> $aucivpbextinf.obs$pretty_name
#> [1] "AUCbext (based on AUCinf,obs)"
#> 
#> $aucivpbextinf.obs$desc
#> [1] "The back-extrapolation percent for intravenous dosing based on AUCinf,obs"
#> 
#> $aucivpbextinf.obs$sparse
#> [1] FALSE
#> 
#> $aucivpbextinf.obs$formalsmap
#> $aucivpbextinf.obs$formalsmap$auc
#> [1] "aucinf.obs"
#> 
#> $aucivpbextinf.obs$formalsmap$auciv
#> [1] "aucivinf.obs"
#> 
#> 
#> $aucivpbextinf.obs$depends
#> [1] "aucinf.obs"   "aucivinf.obs"
#> 
#> $aucivpbextinf.obs$datatype
#> [1] "interval"
#> 
#> $aucivpbextinf.obs$pptestcd_cdisc
#> [1] "AUCIVPEI"
#> 
#> $aucivpbextinf.obs$pptest_cdisc
#> [1] "AUCbext (based on AUCinf,obs)"
#> 
#> 
#> $aucivpbextinf.pred
#> $aucivpbextinf.pred$FUN
#> [1] "pk.calc.auciv_pbext"
#> 
#> $aucivpbextinf.pred$values
#> [1] FALSE  TRUE
#> 
#> $aucivpbextinf.pred$unit_type
#> [1] "%"
#> 
#> $aucivpbextinf.pred$pretty_name
#> [1] "AUCbext (based on AUCinf,pred)"
#> 
#> $aucivpbextinf.pred$desc
#> [1] "The back-extrapolation percent for intravenous dosing based on AUCinf,pred"
#> 
#> $aucivpbextinf.pred$sparse
#> [1] FALSE
#> 
#> $aucivpbextinf.pred$formalsmap
#> $aucivpbextinf.pred$formalsmap$auc
#> [1] "aucinf.pred"
#> 
#> $aucivpbextinf.pred$formalsmap$auciv
#> [1] "aucivinf.pred"
#> 
#> 
#> $aucivpbextinf.pred$depends
#> [1] "aucinf.pred"   "aucivinf.pred"
#> 
#> $aucivpbextinf.pred$datatype
#> [1] "interval"
#> 
#> $aucivpbextinf.pred$pptestcd_cdisc
#> [1] "AUCIVPEP"
#> 
#> $aucivpbextinf.pred$pptest_cdisc
#> [1] "AUCbext (based on AUCinf,pred)"
#> 
#> 
#> $aumcivinf.obs
#> $aumcivinf.obs$FUN
#> [1] "pk.calc.aumciv"
#> 
#> $aumcivinf.obs$values
#> [1] FALSE  TRUE
#> 
#> $aumcivinf.obs$unit_type
#> [1] "aumc"
#> 
#> $aumcivinf.obs$pretty_name
#> [1] "AUMCinf,obs (IV dosing)"
#> 
#> $aumcivinf.obs$desc
#> [1] "The AUMCinf,obs calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#> 
#> $aumcivinf.obs$sparse
#> [1] FALSE
#> 
#> $aumcivinf.obs$formalsmap
#> $aumcivinf.obs$formalsmap$aumc
#> [1] "aumcinf.obs"
#> 
#> 
#> $aumcivinf.obs$depends
#> [1] "aumcinf.obs" "c0"         
#> 
#> $aumcivinf.obs$datatype
#> [1] "interval"
#> 
#> $aumcivinf.obs$pptestcd_cdisc
#> [1] "aumcivinf.obs"
#> 
#> $aumcivinf.obs$pptest_cdisc
#> [1] "The AUMCinf,obs calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#> 
#> 
#> $aumcivinf.pred
#> $aumcivinf.pred$FUN
#> [1] "pk.calc.aumciv"
#> 
#> $aumcivinf.pred$values
#> [1] FALSE  TRUE
#> 
#> $aumcivinf.pred$unit_type
#> [1] "aumc"
#> 
#> $aumcivinf.pred$pretty_name
#> [1] "AUMCinf,pred (IV dosing)"
#> 
#> $aumcivinf.pred$desc
#> [1] "The AUMCinf,pred calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#> 
#> $aumcivinf.pred$sparse
#> [1] FALSE
#> 
#> $aumcivinf.pred$formalsmap
#> $aumcivinf.pred$formalsmap$aumc
#> [1] "aumcinf.pred"
#> 
#> 
#> $aumcivinf.pred$depends
#> [1] "aumcinf.pred" "c0"          
#> 
#> $aumcivinf.pred$datatype
#> [1] "interval"
#> 
#> $aumcivinf.pred$pptestcd_cdisc
#> [1] "aumcivinf.pred"
#> 
#> $aumcivinf.pred$pptest_cdisc
#> [1] "The AUMCinf,pred calculated with back-extrapolation for intravenous dosing using extrapolated C0"
#> 
#> 
#> $aucpext.obs
#> $aucpext.obs$FUN
#> [1] "pk.calc.aucpext"
#> 
#> $aucpext.obs$values
#> [1] FALSE  TRUE
#> 
#> $aucpext.obs$unit_type
#> [1] "%"
#> 
#> $aucpext.obs$pretty_name
#> [1] "AUCpext (based on AUCinf,obs)"
#> 
#> $aucpext.obs$desc
#> [1] "Percent of the AUCinf that is extrapolated after Tlast calculated from the observed Clast"
#> 
#> $aucpext.obs$sparse
#> [1] FALSE
#> 
#> $aucpext.obs$formalsmap
#> $aucpext.obs$formalsmap$aucinf
#> [1] "aucinf.obs"
#> 
#> 
#> $aucpext.obs$depends
#> [1] "auclast"    "aucinf.obs"
#> 
#> $aucpext.obs$datatype
#> [1] "interval"
#> 
#> $aucpext.obs$pptestcd_cdisc
#> [1] "AUCPEO"
#> 
#> $aucpext.obs$pptest_cdisc
#> [1] "AUC %Extrapolation Obs"
#> 
#> 
#> $aucpext.pred
#> $aucpext.pred$FUN
#> [1] "pk.calc.aucpext"
#> 
#> $aucpext.pred$values
#> [1] FALSE  TRUE
#> 
#> $aucpext.pred$unit_type
#> [1] "%"
#> 
#> $aucpext.pred$pretty_name
#> [1] "AUCpext (based on AUCinf,pred)"
#> 
#> $aucpext.pred$desc
#> [1] "Percent of the AUCinf that is extrapolated after Tlast calculated from the predicted Clast"
#> 
#> $aucpext.pred$sparse
#> [1] FALSE
#> 
#> $aucpext.pred$formalsmap
#> $aucpext.pred$formalsmap$aucinf
#> [1] "aucinf.pred"
#> 
#> 
#> $aucpext.pred$depends
#> [1] "auclast"     "aucinf.pred"
#> 
#> $aucpext.pred$datatype
#> [1] "interval"
#> 
#> $aucpext.pred$pptestcd_cdisc
#> [1] "AUCPEP"
#> 
#> $aucpext.pred$pptest_cdisc
#> [1] "AUC %Extrapolation Pred"
#> 
#> 
#> $kel.iv.all
#> $kel.iv.all$FUN
#> [1] "pk.calc.kel"
#> 
#> $kel.iv.all$values
#> [1] FALSE  TRUE
#> 
#> $kel.iv.all$unit_type
#> [1] "inverse_time"
#> 
#> $kel.iv.all$pretty_name
#> [1] "Kel (for IV dosing,  based on AUCall)"
#> 
#> $kel.iv.all$desc
#> [1] "Elimination rate (as calculated from the MRTiv.all))"
#> 
#> $kel.iv.all$sparse
#> [1] FALSE
#> 
#> $kel.iv.all$formalsmap
#> $kel.iv.all$formalsmap$mrt
#> [1] "mrt.iv.all"
#> 
#> 
#> $kel.iv.all$depends
#> [1] "mrt.iv.all"
#> 
#> $kel.iv.all$datatype
#> [1] "interval"
#> 
#> $kel.iv.all$pptestcd_cdisc
#> [1] "kel.iv.all"
#> 
#> $kel.iv.all$pptest_cdisc
#> [1] "Elimination rate (as calculated from the MRTiv.all))"
#> 
#> 
#> $kel.ivint.all
#> $kel.ivint.all$FUN
#> [1] "pk.calc.kel"
#> 
#> $kel.ivint.all$values
#> [1] FALSE  TRUE
#> 
#> $kel.ivint.all$unit_type
#> [1] "inverse_time"
#> 
#> $kel.ivint.all$pretty_name
#> [1] "Kel (IV dose interval, based on AUCint.all)"
#> 
#> $kel.ivint.all$desc
#> [1] "Elimination rate (as calculated from the MRTivint.all)"
#> 
#> $kel.ivint.all$sparse
#> [1] FALSE
#> 
#> $kel.ivint.all$formalsmap
#> $kel.ivint.all$formalsmap$mrt
#> [1] "mrt.ivint.all"
#> 
#> 
#> $kel.ivint.all$depends
#> [1] "mrt.ivint.all"
#> 
#> $kel.ivint.all$datatype
#> [1] "interval"
#> 
#> $kel.ivint.all$pptestcd_cdisc
#> [1] "kel.ivint.all"
#> 
#> $kel.ivint.all$pptest_cdisc
#> [1] "Elimination rate (as calculated from the MRTivint.all)"
#> 
#> 
#> $kel.ivint.last
#> $kel.ivint.last$FUN
#> [1] "pk.calc.kel"
#> 
#> $kel.ivint.last$values
#> [1] FALSE  TRUE
#> 
#> $kel.ivint.last$unit_type
#> [1] "inverse_time"
#> 
#> $kel.ivint.last$pretty_name
#> [1] "Kel (IV dose interval, based on AUCint.last)"
#> 
#> $kel.ivint.last$desc
#> [1] "Elimination rate (as calculated from the MRTivint.last)"
#> 
#> $kel.ivint.last$sparse
#> [1] FALSE
#> 
#> $kel.ivint.last$formalsmap
#> $kel.ivint.last$formalsmap$mrt
#> [1] "mrt.ivint.last"
#> 
#> 
#> $kel.ivint.last$depends
#> [1] "mrt.ivint.last"
#> 
#> $kel.ivint.last$datatype
#> [1] "interval"
#> 
#> $kel.ivint.last$pptestcd_cdisc
#> [1] "kel.ivint.last"
#> 
#> $kel.ivint.last$pptest_cdisc
#> [1] "Elimination rate (as calculated from the MRTivint.last)"
#> 
#> 
#> $kel.sparse.last
#> $kel.sparse.last$FUN
#> [1] "pk.calc.kel"
#> 
#> $kel.sparse.last$values
#> [1] FALSE  TRUE
#> 
#> $kel.sparse.last$unit_type
#> [1] "inverse_time"
#> 
#> $kel.sparse.last$pretty_name
#> [1] "Kel (for sparse data, based on AUClast)"
#> 
#> $kel.sparse.last$desc
#> [1] "Elimination rate (as calculated from the MRTsparse.last)"
#> 
#> $kel.sparse.last$sparse
#> [1] TRUE
#> 
#> $kel.sparse.last$formalsmap
#> $kel.sparse.last$formalsmap$mrt
#> [1] "mrt.sparse.last"
#> 
#> 
#> $kel.sparse.last$depends
#> [1] "mrt.sparse.last"
#> 
#> $kel.sparse.last$datatype
#> [1] "interval"
#> 
#> $kel.sparse.last$pptestcd_cdisc
#> [1] "kel.sparse.last"
#> 
#> $kel.sparse.last$pptest_cdisc
#> [1] "Elimination rate (as calculated from the MRTsparse.last)"
#> 
#> 
#> $cl.obs
#> $cl.obs$FUN
#> [1] "pk.calc.cl"
#> 
#> $cl.obs$values
#> [1] FALSE  TRUE
#> 
#> $cl.obs$unit_type
#> [1] "clearance"
#> 
#> $cl.obs$pretty_name
#> [1] "CL (based on AUCinf,obs)"
#> 
#> $cl.obs$desc
#> [1] "Clearance or observed oral clearance calculated with observed Clast"
#> 
#> $cl.obs$sparse
#> [1] FALSE
#> 
#> $cl.obs$formalsmap
#> $cl.obs$formalsmap$auc
#> [1] "aucinf.obs"
#> 
#> 
#> $cl.obs$depends
#> [1] "aucinf.obs"
#> 
#> $cl.obs$datatype
#> [1] "interval"
#> 
#> $cl.obs$pptestcd_cdisc
#> $cl.obs$pptestcd_cdisc$route
#> $cl.obs$pptestcd_cdisc$route$extravascular
#> [1] "CLF/FO"
#> 
#> $cl.obs$pptestcd_cdisc$route$intravascular
#> [1] "CLO"
#> 
#> 
#> 
#> $cl.obs$pptest_cdisc
#> $cl.obs$pptest_cdisc$route
#> $cl.obs$pptest_cdisc$route$extravascular
#> [1] "Total CL Obs by F"
#> 
#> $cl.obs$pptest_cdisc$route$intravascular
#> [1] "Total CL Obs"
#> 
#> 
#> 
#> 
#> $cl.pred
#> $cl.pred$FUN
#> [1] "pk.calc.cl"
#> 
#> $cl.pred$values
#> [1] FALSE  TRUE
#> 
#> $cl.pred$unit_type
#> [1] "clearance"
#> 
#> $cl.pred$pretty_name
#> [1] "CL (based on AUCinf,pred)"
#> 
#> $cl.pred$desc
#> [1] "Clearance or observed oral clearance calculated with predicted Clast"
#> 
#> $cl.pred$sparse
#> [1] FALSE
#> 
#> $cl.pred$formalsmap
#> $cl.pred$formalsmap$auc
#> [1] "aucinf.pred"
#> 
#> 
#> $cl.pred$depends
#> [1] "aucinf.pred"
#> 
#> $cl.pred$datatype
#> [1] "interval"
#> 
#> $cl.pred$pptestcd_cdisc
#> $cl.pred$pptestcd_cdisc$route
#> $cl.pred$pptestcd_cdisc$route$extravascular
#> [1] "CLF/FP"
#> 
#> $cl.pred$pptestcd_cdisc$route$intravascular
#> [1] "CLP"
#> 
#> 
#> 
#> $cl.pred$pptest_cdisc
#> $cl.pred$pptest_cdisc$route
#> $cl.pred$pptest_cdisc$route$extravascular
#> [1] "Total CL Pred by F"
#> 
#> $cl.pred$pptest_cdisc$route$intravascular
#> [1] "Total CL Pred"
#> 
#> 
#> 
#> 
#> $cl.int.inf.obs
#> $cl.int.inf.obs$FUN
#> [1] "pk.calc.cl"
#> 
#> $cl.int.inf.obs$values
#> [1] FALSE  TRUE
#> 
#> $cl.int.inf.obs$unit_type
#> [1] "clearance"
#> 
#> $cl.int.inf.obs$pretty_name
#> [1] "CL (based on AUCint.inf.obs)"
#> 
#> $cl.int.inf.obs$desc
#> [1] "Clearance or observed oral clearance calculated with AUCint.inf.obs"
#> 
#> $cl.int.inf.obs$sparse
#> [1] FALSE
#> 
#> $cl.int.inf.obs$formalsmap
#> $cl.int.inf.obs$formalsmap$auc
#> [1] "aucint.inf.obs"
#> 
#> 
#> $cl.int.inf.obs$depends
#> [1] "aucint.inf.obs"
#> 
#> $cl.int.inf.obs$datatype
#> [1] "interval"
#> 
#> $cl.int.inf.obs$pptestcd_cdisc
#> [1] "cl.int.inf.obs"
#> 
#> $cl.int.inf.obs$pptest_cdisc
#> [1] "Clearance or observed oral clearance calculated with AUCint.inf.obs"
#> 
#> 
#> $cl.int.inf.pred
#> $cl.int.inf.pred$FUN
#> [1] "pk.calc.cl"
#> 
#> $cl.int.inf.pred$values
#> [1] FALSE  TRUE
#> 
#> $cl.int.inf.pred$unit_type
#> [1] "clearance"
#> 
#> $cl.int.inf.pred$pretty_name
#> [1] "CL (based on AUCint.inf.pred)"
#> 
#> $cl.int.inf.pred$desc
#> [1] "Clearance or observed oral clearance calculated with AUCint.inf.pred"
#> 
#> $cl.int.inf.pred$sparse
#> [1] FALSE
#> 
#> $cl.int.inf.pred$formalsmap
#> $cl.int.inf.pred$formalsmap$auc
#> [1] "aucint.inf.pred"
#> 
#> 
#> $cl.int.inf.pred$depends
#> [1] "aucint.inf.pred"
#> 
#> $cl.int.inf.pred$datatype
#> [1] "interval"
#> 
#> $cl.int.inf.pred$pptestcd_cdisc
#> [1] "cl.int.inf.pred"
#> 
#> $cl.int.inf.pred$pptest_cdisc
#> [1] "Clearance or observed oral clearance calculated with AUCint.inf.pred"
#> 
#> 
#> $cl.iv.obs
#> $cl.iv.obs$FUN
#> [1] "pk.calc.cl"
#> 
#> $cl.iv.obs$values
#> [1] FALSE  TRUE
#> 
#> $cl.iv.obs$unit_type
#> [1] "clearance"
#> 
#> $cl.iv.obs$pretty_name
#> [1] "CL (for IV dosing,  based on AUCinf,obs)"
#> 
#> $cl.iv.obs$desc
#> [1] "Clearance for intravenous dosing calculated with AUCinf,obs"
#> 
#> $cl.iv.obs$sparse
#> [1] FALSE
#> 
#> $cl.iv.obs$formalsmap
#> $cl.iv.obs$formalsmap$auc
#> [1] "aucivinf.obs"
#> 
#> 
#> $cl.iv.obs$depends
#> [1] "aucivinf.obs"
#> 
#> $cl.iv.obs$datatype
#> [1] "interval"
#> 
#> $cl.iv.obs$pptestcd_cdisc
#> [1] "cl.iv.obs"
#> 
#> $cl.iv.obs$pptest_cdisc
#> [1] "Clearance for intravenous dosing calculated with AUCinf,obs"
#> 
#> 
#> $cl.iv.pred
#> $cl.iv.pred$FUN
#> [1] "pk.calc.cl"
#> 
#> $cl.iv.pred$values
#> [1] FALSE  TRUE
#> 
#> $cl.iv.pred$unit_type
#> [1] "clearance"
#> 
#> $cl.iv.pred$pretty_name
#> [1] "CL (for IV dosing,  based on AUCinf,pred)"
#> 
#> $cl.iv.pred$desc
#> [1] "Clearance for intravenous dosing calculated with AUCinf,pred"
#> 
#> $cl.iv.pred$sparse
#> [1] FALSE
#> 
#> $cl.iv.pred$formalsmap
#> $cl.iv.pred$formalsmap$auc
#> [1] "aucivinf.pred"
#> 
#> 
#> $cl.iv.pred$depends
#> [1] "aucivinf.pred"
#> 
#> $cl.iv.pred$datatype
#> [1] "interval"
#> 
#> $cl.iv.pred$pptestcd_cdisc
#> [1] "cl.iv.pred"
#> 
#> $cl.iv.pred$pptest_cdisc
#> [1] "Clearance for intravenous dosing calculated with AUCinf,pred"
#> 
#> 
#> $mrt.obs
#> $mrt.obs$FUN
#> [1] "pk.calc.mrt"
#> 
#> $mrt.obs$values
#> [1] FALSE  TRUE
#> 
#> $mrt.obs$unit_type
#> [1] "time"
#> 
#> $mrt.obs$pretty_name
#> [1] "MRT (based on AUCinf,obs)"
#> 
#> $mrt.obs$desc
#> [1] "The mean residence time to infinity using observed Clast"
#> 
#> $mrt.obs$sparse
#> [1] FALSE
#> 
#> $mrt.obs$formalsmap
#> $mrt.obs$formalsmap$auc
#> [1] "aucinf.obs"
#> 
#> $mrt.obs$formalsmap$aumc
#> [1] "aumcinf.obs"
#> 
#> 
#> $mrt.obs$depends
#> [1] "aucinf.obs"  "aumcinf.obs"
#> 
#> $mrt.obs$datatype
#> [1] "interval"
#> 
#> $mrt.obs$pptestcd_cdisc
#> $mrt.obs$pptestcd_cdisc$route
#> $mrt.obs$pptestcd_cdisc$route$extravascular
#> [1] "MRTEVFO"
#> 
#> $mrt.obs$pptestcd_cdisc$route$intravascular
#> [1] "MRTICFO"
#> 
#> 
#> 
#> $mrt.obs$pptest_cdisc
#> $mrt.obs$pptest_cdisc$route
#> $mrt.obs$pptest_cdisc$route$extravascular
#> [1] "MRT Extravasc Infinity Obs"
#> 
#> $mrt.obs$pptest_cdisc$route$intravascular
#> [1] "MRT IV Cont Inf Infinity Obs"
#> 
#> 
#> 
#> 
#> $mrt.pred
#> $mrt.pred$FUN
#> [1] "pk.calc.mrt"
#> 
#> $mrt.pred$values
#> [1] FALSE  TRUE
#> 
#> $mrt.pred$unit_type
#> [1] "time"
#> 
#> $mrt.pred$pretty_name
#> [1] "MRT (based on AUCinf,pred)"
#> 
#> $mrt.pred$desc
#> [1] "The mean residence time to infinity using predicted Clast"
#> 
#> $mrt.pred$sparse
#> [1] FALSE
#> 
#> $mrt.pred$formalsmap
#> $mrt.pred$formalsmap$auc
#> [1] "aucinf.pred"
#> 
#> $mrt.pred$formalsmap$aumc
#> [1] "aumcinf.pred"
#> 
#> 
#> $mrt.pred$depends
#> [1] "aucinf.pred"  "aumcinf.pred"
#> 
#> $mrt.pred$datatype
#> [1] "interval"
#> 
#> $mrt.pred$pptestcd_cdisc
#> $mrt.pred$pptestcd_cdisc$route
#> $mrt.pred$pptestcd_cdisc$route$extravascular
#> [1] "MRTEVFP"
#> 
#> $mrt.pred$pptestcd_cdisc$route$intravascular
#> [1] "MRTICFP"
#> 
#> 
#> 
#> $mrt.pred$pptest_cdisc
#> $mrt.pred$pptest_cdisc$route
#> $mrt.pred$pptest_cdisc$route$extravascular
#> [1] "MRT Extravasc Infinity Pred"
#> 
#> $mrt.pred$pptest_cdisc$route$intravascular
#> [1] "MRT IV Cont Inf Infinity Pred"
#> 
#> 
#> 
#> 
#> $mrt.int.inf.obs
#> $mrt.int.inf.obs$FUN
#> [1] "pk.calc.mrt"
#> 
#> $mrt.int.inf.obs$values
#> [1] FALSE  TRUE
#> 
#> $mrt.int.inf.obs$unit_type
#> [1] "time"
#> 
#> $mrt.int.inf.obs$pretty_name
#> [1] "MRT (based on AUCint.inf.obs)"
#> 
#> $mrt.int.inf.obs$desc
#> [1] "Mean residence time over interval calculated with AUCint.inf.obs/AUMCint.inf.obs"
#> 
#> $mrt.int.inf.obs$sparse
#> [1] FALSE
#> 
#> $mrt.int.inf.obs$formalsmap
#> $mrt.int.inf.obs$formalsmap$auc
#> [1] "aucint.inf.obs"
#> 
#> $mrt.int.inf.obs$formalsmap$aumc
#> [1] "aumcint.inf.obs"
#> 
#> 
#> $mrt.int.inf.obs$depends
#> [1] "aucint.inf.obs"  "aumcint.inf.obs"
#> 
#> $mrt.int.inf.obs$datatype
#> [1] "interval"
#> 
#> $mrt.int.inf.obs$pptestcd_cdisc
#> [1] "mrt.int.inf.obs"
#> 
#> $mrt.int.inf.obs$pptest_cdisc
#> [1] "Mean residence time over interval calculated with AUCint.inf.obs/AUMCint.inf.obs"
#> 
#> 
#> $mrt.int.inf.pred
#> $mrt.int.inf.pred$FUN
#> [1] "pk.calc.mrt"
#> 
#> $mrt.int.inf.pred$values
#> [1] FALSE  TRUE
#> 
#> $mrt.int.inf.pred$unit_type
#> [1] "time"
#> 
#> $mrt.int.inf.pred$pretty_name
#> [1] "MRT (based on AUCint.inf.pred)"
#> 
#> $mrt.int.inf.pred$desc
#> [1] "Mean residence time over interval calculated with AUCint.inf.pred/AUMCint.inf.pred"
#> 
#> $mrt.int.inf.pred$sparse
#> [1] FALSE
#> 
#> $mrt.int.inf.pred$formalsmap
#> $mrt.int.inf.pred$formalsmap$auc
#> [1] "aucint.inf.pred"
#> 
#> $mrt.int.inf.pred$formalsmap$aumc
#> [1] "aumcint.inf.pred"
#> 
#> 
#> $mrt.int.inf.pred$depends
#> [1] "aucint.inf.pred"  "aumcint.inf.pred"
#> 
#> $mrt.int.inf.pred$datatype
#> [1] "interval"
#> 
#> $mrt.int.inf.pred$pptestcd_cdisc
#> [1] "mrt.int.inf.pred"
#> 
#> $mrt.int.inf.pred$pptest_cdisc
#> [1] "Mean residence time over interval calculated with AUCint.inf.pred/AUMCint.inf.pred"
#> 
#> 
#> $mrt.iv.obs
#> $mrt.iv.obs$FUN
#> [1] "pk.calc.mrt.iv"
#> 
#> $mrt.iv.obs$values
#> [1] FALSE  TRUE
#> 
#> $mrt.iv.obs$unit_type
#> [1] "time"
#> 
#> $mrt.iv.obs$pretty_name
#> [1] "MRT (for IV dosing, based on AUCinf,obs)"
#> 
#> $mrt.iv.obs$desc
#> [1] "The mean residence time to infinity using observed Clast correcting for dosing duration"
#> 
#> $mrt.iv.obs$sparse
#> [1] FALSE
#> 
#> $mrt.iv.obs$formalsmap
#> $mrt.iv.obs$formalsmap$auc
#> [1] "aucinf.obs"
#> 
#> $mrt.iv.obs$formalsmap$aumc
#> [1] "aumcinf.obs"
#> 
#> 
#> $mrt.iv.obs$depends
#> [1] "aucinf.obs"  "aumcinf.obs"
#> 
#> $mrt.iv.obs$datatype
#> [1] "interval"
#> 
#> $mrt.iv.obs$pptestcd_cdisc
#> [1] "MRTIBIFO"
#> 
#> $mrt.iv.obs$pptest_cdisc
#> [1] "MRT Intravasc Infinity Obs"
#> 
#> 
#> $mrt.iv.pred
#> $mrt.iv.pred$FUN
#> [1] "pk.calc.mrt.iv"
#> 
#> $mrt.iv.pred$values
#> [1] FALSE  TRUE
#> 
#> $mrt.iv.pred$unit_type
#> [1] "time"
#> 
#> $mrt.iv.pred$pretty_name
#> [1] "MRT (for IV dosing, based on AUCinf,pred)"
#> 
#> $mrt.iv.pred$desc
#> [1] "The mean residence time to infinity using predicted Clast correcting for dosing duration"
#> 
#> $mrt.iv.pred$sparse
#> [1] FALSE
#> 
#> $mrt.iv.pred$formalsmap
#> $mrt.iv.pred$formalsmap$auc
#> [1] "aucinf.pred"
#> 
#> $mrt.iv.pred$formalsmap$aumc
#> [1] "aumcinf.pred"
#> 
#> 
#> $mrt.iv.pred$depends
#> [1] "aucinf.pred"  "aumcinf.pred"
#> 
#> $mrt.iv.pred$datatype
#> [1] "interval"
#> 
#> $mrt.iv.pred$pptestcd_cdisc
#> [1] "MRTIBIFP"
#> 
#> $mrt.iv.pred$pptest_cdisc
#> [1] "MRT Intravasc Infinity Pred"
#> 
#> 
#> $mrt.md.obs
#> $mrt.md.obs$FUN
#> [1] "pk.calc.mrt.md"
#> 
#> $mrt.md.obs$values
#> [1] FALSE  TRUE
#> 
#> $mrt.md.obs$unit_type
#> [1] "time"
#> 
#> $mrt.md.obs$pretty_name
#> [1] "MRT (for multiple dosing, based on AUCinf,obs)"
#> 
#> $mrt.md.obs$desc
#> [1] "The mean residence time with multiple dosing and nonlinear kinetics using observed Clast"
#> 
#> $mrt.md.obs$sparse
#> [1] FALSE
#> 
#> $mrt.md.obs$formalsmap
#> $mrt.md.obs$formalsmap$auctau
#> [1] "auclast"
#> 
#> $mrt.md.obs$formalsmap$aumctau
#> [1] "aumclast"
#> 
#> $mrt.md.obs$formalsmap$aucinf
#> [1] "aucinf.obs"
#> 
#> 
#> $mrt.md.obs$depends
#> [1] "auclast"    "aumclast"   "aucinf.obs"
#> 
#> $mrt.md.obs$datatype
#> [1] "interval"
#> 
#> $mrt.md.obs$pptestcd_cdisc
#> [1] "MRTMDO"
#> 
#> $mrt.md.obs$pptest_cdisc
#> [1] "MRT (for multiple dosing, based on AUCinf,obs)"
#> 
#> 
#> $mrt.md.pred
#> $mrt.md.pred$FUN
#> [1] "pk.calc.mrt.md"
#> 
#> $mrt.md.pred$values
#> [1] FALSE  TRUE
#> 
#> $mrt.md.pred$unit_type
#> [1] "time"
#> 
#> $mrt.md.pred$pretty_name
#> [1] "MRT (for multiple dosing, based on AUCinf,pred)"
#> 
#> $mrt.md.pred$desc
#> [1] "The mean residence time with multiple dosing and nonlinear kinetics using predicted Clast"
#> 
#> $mrt.md.pred$sparse
#> [1] FALSE
#> 
#> $mrt.md.pred$formalsmap
#> $mrt.md.pred$formalsmap$auctau
#> [1] "auclast"
#> 
#> $mrt.md.pred$formalsmap$aumctau
#> [1] "aumclast"
#> 
#> $mrt.md.pred$formalsmap$aucinf
#> [1] "aucinf.pred"
#> 
#> 
#> $mrt.md.pred$depends
#> [1] "auclast"     "aumclast"    "aucinf.pred"
#> 
#> $mrt.md.pred$datatype
#> [1] "interval"
#> 
#> $mrt.md.pred$pptestcd_cdisc
#> [1] "MRTMDP"
#> 
#> $mrt.md.pred$pptest_cdisc
#> [1] "MRT (for multiple dosing, based on AUCinf,pred)"
#> 
#> 
#> $vz.obs
#> $vz.obs$FUN
#> [1] "pk.calc.vz"
#> 
#> $vz.obs$values
#> [1] FALSE  TRUE
#> 
#> $vz.obs$unit_type
#> [1] "volume"
#> 
#> $vz.obs$pretty_name
#> [1] "Vz (based on AUCinf,obs)"
#> 
#> $vz.obs$desc
#> [1] "The terminal volume of distribution using observed Clast"
#> 
#> $vz.obs$sparse
#> [1] FALSE
#> 
#> $vz.obs$formalsmap
#> $vz.obs$formalsmap$cl
#> [1] "cl.obs"
#> 
#> 
#> $vz.obs$depends
#> [1] "cl.obs"   "lambda.z"
#> 
#> $vz.obs$datatype
#> [1] "interval"
#> 
#> $vz.obs$pptestcd_cdisc
#> $vz.obs$pptestcd_cdisc$route
#> $vz.obs$pptestcd_cdisc$route$extravascular
#> [1] "VZF/FO"
#> 
#> $vz.obs$pptestcd_cdisc$route$intravascular
#> [1] "VZO"
#> 
#> 
#> 
#> $vz.obs$pptest_cdisc
#> $vz.obs$pptest_cdisc$route
#> $vz.obs$pptest_cdisc$route$extravascular
#> [1] "Vz by F Obs"
#> 
#> $vz.obs$pptest_cdisc$route$intravascular
#> [1] "Vz Obs"
#> 
#> 
#> 
#> 
#> $vz.pred
#> $vz.pred$FUN
#> [1] "pk.calc.vz"
#> 
#> $vz.pred$values
#> [1] FALSE  TRUE
#> 
#> $vz.pred$unit_type
#> [1] "volume"
#> 
#> $vz.pred$pretty_name
#> [1] "Vz (based on AUCinf,pred)"
#> 
#> $vz.pred$desc
#> [1] "The terminal volume of distribution using predicted Clast"
#> 
#> $vz.pred$sparse
#> [1] FALSE
#> 
#> $vz.pred$formalsmap
#> $vz.pred$formalsmap$cl
#> [1] "cl.pred"
#> 
#> 
#> $vz.pred$depends
#> [1] "cl.pred"  "lambda.z"
#> 
#> $vz.pred$datatype
#> [1] "interval"
#> 
#> $vz.pred$pptestcd_cdisc
#> $vz.pred$pptestcd_cdisc$route
#> $vz.pred$pptestcd_cdisc$route$extravascular
#> [1] "VZF/FP"
#> 
#> $vz.pred$pptestcd_cdisc$route$intravascular
#> [1] "VZP"
#> 
#> 
#> 
#> $vz.pred$pptest_cdisc
#> $vz.pred$pptest_cdisc$route
#> $vz.pred$pptest_cdisc$route$extravascular
#> [1] "Vz by F Pred"
#> 
#> $vz.pred$pptest_cdisc$route$intravascular
#> [1] "Vz Pred"
#> 
#> 
#> 
#> 
#> $vz.int.inf.obs
#> $vz.int.inf.obs$FUN
#> [1] "pk.calc.vz"
#> 
#> $vz.int.inf.obs$values
#> [1] FALSE  TRUE
#> 
#> $vz.int.inf.obs$unit_type
#> [1] "volume"
#> 
#> $vz.int.inf.obs$pretty_name
#> [1] "Vz (based on AUCint.inf.obs)"
#> 
#> $vz.int.inf.obs$desc
#> [1] "Terminal volume of distribution using interval AUCint.inf.obs"
#> 
#> $vz.int.inf.obs$sparse
#> [1] FALSE
#> 
#> $vz.int.inf.obs$formalsmap
#> $vz.int.inf.obs$formalsmap$cl
#> [1] "cl.int.inf.obs"
#> 
#> 
#> $vz.int.inf.obs$depends
#> [1] "cl.int.inf.obs" "lambda.z"      
#> 
#> $vz.int.inf.obs$datatype
#> [1] "interval"
#> 
#> $vz.int.inf.obs$pptestcd_cdisc
#> [1] "vz.int.inf.obs"
#> 
#> $vz.int.inf.obs$pptest_cdisc
#> [1] "Terminal volume of distribution using interval AUCint.inf.obs"
#> 
#> 
#> $vz.int.inf.pred
#> $vz.int.inf.pred$FUN
#> [1] "pk.calc.vz"
#> 
#> $vz.int.inf.pred$values
#> [1] FALSE  TRUE
#> 
#> $vz.int.inf.pred$unit_type
#> [1] "volume"
#> 
#> $vz.int.inf.pred$pretty_name
#> [1] "Vz (based on AUCint.inf.pred)"
#> 
#> $vz.int.inf.pred$desc
#> [1] "Terminal volume of distribution using interval AUCint.inf.pred"
#> 
#> $vz.int.inf.pred$sparse
#> [1] FALSE
#> 
#> $vz.int.inf.pred$formalsmap
#> $vz.int.inf.pred$formalsmap$cl
#> [1] "cl.int.inf.pred"
#> 
#> 
#> $vz.int.inf.pred$depends
#> [1] "cl.int.inf.pred" "lambda.z"       
#> 
#> $vz.int.inf.pred$datatype
#> [1] "interval"
#> 
#> $vz.int.inf.pred$pptestcd_cdisc
#> [1] "vz.int.inf.pred"
#> 
#> $vz.int.inf.pred$pptest_cdisc
#> [1] "Terminal volume of distribution using interval AUCint.inf.pred"
#> 
#> 
#> $vz.iv.obs
#> $vz.iv.obs$FUN
#> [1] "pk.calc.vz"
#> 
#> $vz.iv.obs$values
#> [1] FALSE  TRUE
#> 
#> $vz.iv.obs$unit_type
#> [1] "volume"
#> 
#> $vz.iv.obs$pretty_name
#> [1] "Vz (for IV dosing,  based on AUCinf,obs)"
#> 
#> $vz.iv.obs$desc
#> [1] "Terminal volume of distribution for IV dosing using observed AUCinf"
#> 
#> $vz.iv.obs$sparse
#> [1] FALSE
#> 
#> $vz.iv.obs$formalsmap
#> $vz.iv.obs$formalsmap$cl
#> [1] "cl.iv.obs"
#> 
#> 
#> $vz.iv.obs$depends
#> [1] "cl.iv.obs" "lambda.z" 
#> 
#> $vz.iv.obs$datatype
#> [1] "interval"
#> 
#> $vz.iv.obs$pptestcd_cdisc
#> [1] "vz.iv.obs"
#> 
#> $vz.iv.obs$pptest_cdisc
#> [1] "Terminal volume of distribution for IV dosing using observed AUCinf"
#> 
#> 
#> $vz.iv.pred
#> $vz.iv.pred$FUN
#> [1] "pk.calc.vz"
#> 
#> $vz.iv.pred$values
#> [1] FALSE  TRUE
#> 
#> $vz.iv.pred$unit_type
#> [1] "volume"
#> 
#> $vz.iv.pred$pretty_name
#> [1] "Vz (for IV dosing,  based on AUCinf,pred)"
#> 
#> $vz.iv.pred$desc
#> [1] "Terminal volume of distribution for IV dosing using predicted AUCinf"
#> 
#> $vz.iv.pred$sparse
#> [1] FALSE
#> 
#> $vz.iv.pred$formalsmap
#> $vz.iv.pred$formalsmap$cl
#> [1] "cl.iv.pred"
#> 
#> 
#> $vz.iv.pred$depends
#> [1] "cl.iv.pred" "lambda.z"  
#> 
#> $vz.iv.pred$datatype
#> [1] "interval"
#> 
#> $vz.iv.pred$pptestcd_cdisc
#> [1] "vz.iv.pred"
#> 
#> $vz.iv.pred$pptest_cdisc
#> [1] "Terminal volume of distribution for IV dosing using predicted AUCinf"
#> 
#> 
#> $vz.sparse.last
#> $vz.sparse.last$FUN
#> [1] "pk.calc.vz"
#> 
#> $vz.sparse.last$values
#> [1] FALSE  TRUE
#> 
#> $vz.sparse.last$unit_type
#> [1] "volume"
#> 
#> $vz.sparse.last$pretty_name
#> [1] "Vz (for sparse data, based on AUClast)"
#> 
#> $vz.sparse.last$desc
#> [1] "Terminal volume of distribution from sparse sampling"
#> 
#> $vz.sparse.last$sparse
#> [1] TRUE
#> 
#> $vz.sparse.last$formalsmap
#> $vz.sparse.last$formalsmap$cl
#> [1] "cl.sparse.last"
#> 
#> $vz.sparse.last$formalsmap$lambda.z
#> [1] "kel.sparse.last"
#> 
#> 
#> $vz.sparse.last$depends
#> [1] "cl.sparse.last"  "kel.sparse.last"
#> 
#> $vz.sparse.last$datatype
#> [1] "interval"
#> 
#> $vz.sparse.last$pptestcd_cdisc
#> [1] "vz.sparse.last"
#> 
#> $vz.sparse.last$pptest_cdisc
#> [1] "Terminal volume of distribution from sparse sampling"
#> 
#> 
#> $vss.obs
#> $vss.obs$FUN
#> [1] "pk.calc.vss"
#> 
#> $vss.obs$values
#> [1] FALSE  TRUE
#> 
#> $vss.obs$unit_type
#> [1] "volume"
#> 
#> $vss.obs$pretty_name
#> [1] "Vss (based on AUCinf,obs)"
#> 
#> $vss.obs$desc
#> [1] "The steady-state volume of distribution using observed Clast"
#> 
#> $vss.obs$sparse
#> [1] FALSE
#> 
#> $vss.obs$formalsmap
#> $vss.obs$formalsmap$cl
#> [1] "cl.obs"
#> 
#> $vss.obs$formalsmap$mrt
#> [1] "mrt.obs"
#> 
#> 
#> $vss.obs$depends
#> [1] "cl.obs"  "mrt.obs"
#> 
#> $vss.obs$datatype
#> [1] "interval"
#> 
#> $vss.obs$pptestcd_cdisc
#> $vss.obs$pptestcd_cdisc$route
#> $vss.obs$pptestcd_cdisc$route$extravascular
#> [1] "VSSF/FO"
#> 
#> $vss.obs$pptestcd_cdisc$route$intravascular
#> [1] "VSSO"
#> 
#> 
#> 
#> $vss.obs$pptest_cdisc
#> $vss.obs$pptest_cdisc$route
#> $vss.obs$pptest_cdisc$route$extravascular
#> [1] "Vss by F Obs"
#> 
#> $vss.obs$pptest_cdisc$route$intravascular
#> [1] "Vol Dist Steady State Obs"
#> 
#> 
#> 
#> 
#> $vss.pred
#> $vss.pred$FUN
#> [1] "pk.calc.vss"
#> 
#> $vss.pred$values
#> [1] FALSE  TRUE
#> 
#> $vss.pred$unit_type
#> [1] "volume"
#> 
#> $vss.pred$pretty_name
#> [1] "Vss (based on AUCinf,pred)"
#> 
#> $vss.pred$desc
#> [1] "The steady-state volume of distribution using predicted Clast"
#> 
#> $vss.pred$sparse
#> [1] FALSE
#> 
#> $vss.pred$formalsmap
#> $vss.pred$formalsmap$cl
#> [1] "cl.pred"
#> 
#> $vss.pred$formalsmap$mrt
#> [1] "mrt.pred"
#> 
#> 
#> $vss.pred$depends
#> [1] "cl.pred"  "mrt.pred"
#> 
#> $vss.pred$datatype
#> [1] "interval"
#> 
#> $vss.pred$pptestcd_cdisc
#> $vss.pred$pptestcd_cdisc$route
#> $vss.pred$pptestcd_cdisc$route$extravascular
#> [1] "VSSF/FP"
#> 
#> $vss.pred$pptestcd_cdisc$route$intravascular
#> [1] "VSSP"
#> 
#> 
#> 
#> $vss.pred$pptest_cdisc
#> $vss.pred$pptest_cdisc$route
#> $vss.pred$pptest_cdisc$route$extravascular
#> [1] "Vss by F Pred"
#> 
#> $vss.pred$pptest_cdisc$route$intravascular
#> [1] "Vol Dist Steady State Pred"
#> 
#> 
#> 
#> 
#> $vss.iv.obs
#> $vss.iv.obs$FUN
#> [1] "pk.calc.vss"
#> 
#> $vss.iv.obs$values
#> [1] FALSE  TRUE
#> 
#> $vss.iv.obs$unit_type
#> [1] "volume"
#> 
#> $vss.iv.obs$pretty_name
#> [1] "Vss (for IV dosing, based on AUCinf,obs)"
#> 
#> $vss.iv.obs$desc
#> [1] "The steady-state volume of distribution with intravenous infusion using observed Clast"
#> 
#> $vss.iv.obs$sparse
#> [1] FALSE
#> 
#> $vss.iv.obs$formalsmap
#> $vss.iv.obs$formalsmap$cl
#> [1] "cl.obs"
#> 
#> $vss.iv.obs$formalsmap$mrt
#> [1] "mrt.iv.obs"
#> 
#> 
#> $vss.iv.obs$depends
#> [1] "cl.obs"     "mrt.iv.obs"
#> 
#> $vss.iv.obs$datatype
#> [1] "interval"
#> 
#> $vss.iv.obs$pptestcd_cdisc
#> [1] "VSSIVO"
#> 
#> $vss.iv.obs$pptest_cdisc
#> [1] "Vss (for IV dosing, based on AUCinf,obs)"
#> 
#> 
#> $vss.iv.pred
#> $vss.iv.pred$FUN
#> [1] "pk.calc.vss"
#> 
#> $vss.iv.pred$values
#> [1] FALSE  TRUE
#> 
#> $vss.iv.pred$unit_type
#> [1] "volume"
#> 
#> $vss.iv.pred$pretty_name
#> [1] "Vss (for IV dosing, based on AUCinf,pred)"
#> 
#> $vss.iv.pred$desc
#> [1] "The steady-state volume of distribution with intravenous infusion using predicted Clast"
#> 
#> $vss.iv.pred$sparse
#> [1] FALSE
#> 
#> $vss.iv.pred$formalsmap
#> $vss.iv.pred$formalsmap$cl
#> [1] "cl.pred"
#> 
#> $vss.iv.pred$formalsmap$mrt
#> [1] "mrt.iv.pred"
#> 
#> 
#> $vss.iv.pred$depends
#> [1] "cl.pred"     "mrt.iv.pred"
#> 
#> $vss.iv.pred$datatype
#> [1] "interval"
#> 
#> $vss.iv.pred$pptestcd_cdisc
#> [1] "VSSIVP"
#> 
#> $vss.iv.pred$pptest_cdisc
#> [1] "Vss (for IV dosing, based on AUCinf,pred)"
#> 
#> 
#> $vss.md.obs
#> $vss.md.obs$FUN
#> [1] "pk.calc.vss"
#> 
#> $vss.md.obs$values
#> [1] FALSE  TRUE
#> 
#> $vss.md.obs$unit_type
#> [1] "volume"
#> 
#> $vss.md.obs$pretty_name
#> [1] "Vss (for multiple-dose, based on Clast,obs)"
#> 
#> $vss.md.obs$desc
#> [1] "The steady-state volume of distribution for nonlinear multiple-dose data using observed Clast"
#> 
#> $vss.md.obs$sparse
#> [1] FALSE
#> 
#> $vss.md.obs$formalsmap
#> $vss.md.obs$formalsmap$cl
#> [1] "cl.last"
#> 
#> $vss.md.obs$formalsmap$mrt
#> [1] "mrt.md.obs"
#> 
#> 
#> $vss.md.obs$depends
#> [1] "cl.last"    "mrt.md.obs"
#> 
#> $vss.md.obs$datatype
#> [1] "interval"
#> 
#> $vss.md.obs$pptestcd_cdisc
#> [1] "VSSMDO"
#> 
#> $vss.md.obs$pptest_cdisc
#> [1] "Vss (for multiple-dose, based on AUCinf,obs)"
#> 
#> 
#> $vss.md.pred
#> $vss.md.pred$FUN
#> [1] "pk.calc.vss"
#> 
#> $vss.md.pred$values
#> [1] FALSE  TRUE
#> 
#> $vss.md.pred$unit_type
#> [1] "volume"
#> 
#> $vss.md.pred$pretty_name
#> [1] "Vss (for multiple-dose, based on Clast,pred)"
#> 
#> $vss.md.pred$desc
#> [1] "The steady-state volume of distribution for nonlinear multiple-dose data using predicted Clast"
#> 
#> $vss.md.pred$sparse
#> [1] FALSE
#> 
#> $vss.md.pred$formalsmap
#> $vss.md.pred$formalsmap$cl
#> [1] "cl.last"
#> 
#> $vss.md.pred$formalsmap$mrt
#> [1] "mrt.md.pred"
#> 
#> 
#> $vss.md.pred$depends
#> [1] "cl.last"     "mrt.md.pred"
#> 
#> $vss.md.pred$datatype
#> [1] "interval"
#> 
#> $vss.md.pred$pptestcd_cdisc
#> [1] "VSSMDP"
#> 
#> $vss.md.pred$pptest_cdisc
#> [1] "Vss (for multiple-dose, based on AUCinf,pred)"
#> 
#> 
#> $vss.int.inf.obs
#> $vss.int.inf.obs$FUN
#> [1] "pk.calc.vss"
#> 
#> $vss.int.inf.obs$values
#> [1] FALSE  TRUE
#> 
#> $vss.int.inf.obs$unit_type
#> [1] "volume"
#> 
#> $vss.int.inf.obs$pretty_name
#> [1] "Vss (based on AUCint.inf.obs)"
#> 
#> $vss.int.inf.obs$desc
#> [1] "Steady-state volume of distribution using interval AUCint.inf.obs"
#> 
#> $vss.int.inf.obs$sparse
#> [1] FALSE
#> 
#> $vss.int.inf.obs$formalsmap
#> $vss.int.inf.obs$formalsmap$cl
#> [1] "cl.int.inf.obs"
#> 
#> $vss.int.inf.obs$formalsmap$mrt
#> [1] "mrt.int.inf.obs"
#> 
#> 
#> $vss.int.inf.obs$depends
#> [1] "cl.int.inf.obs"  "mrt.int.inf.obs"
#> 
#> $vss.int.inf.obs$datatype
#> [1] "interval"
#> 
#> $vss.int.inf.obs$pptestcd_cdisc
#> [1] "vss.int.inf.obs"
#> 
#> $vss.int.inf.obs$pptest_cdisc
#> [1] "Steady-state volume of distribution using interval AUCint.inf.obs"
#> 
#> 
#> $vss.int.inf.pred
#> $vss.int.inf.pred$FUN
#> [1] "pk.calc.vss"
#> 
#> $vss.int.inf.pred$values
#> [1] FALSE  TRUE
#> 
#> $vss.int.inf.pred$unit_type
#> [1] "volume"
#> 
#> $vss.int.inf.pred$pretty_name
#> [1] "Vss (based on AUCint.inf.pred)"
#> 
#> $vss.int.inf.pred$desc
#> [1] "Steady-state volume of distribution using interval AUCint.inf.pred"
#> 
#> $vss.int.inf.pred$sparse
#> [1] FALSE
#> 
#> $vss.int.inf.pred$formalsmap
#> $vss.int.inf.pred$formalsmap$cl
#> [1] "cl.int.inf.pred"
#> 
#> $vss.int.inf.pred$formalsmap$mrt
#> [1] "mrt.int.inf.pred"
#> 
#> 
#> $vss.int.inf.pred$depends
#> [1] "cl.int.inf.pred"  "mrt.int.inf.pred"
#> 
#> $vss.int.inf.pred$datatype
#> [1] "interval"
#> 
#> $vss.int.inf.pred$pptestcd_cdisc
#> [1] "vss.int.inf.pred"
#> 
#> $vss.int.inf.pred$pptest_cdisc
#> [1] "Steady-state volume of distribution using interval AUCint.inf.pred"
#> 
#> 
#> $cav.int.inf.obs
#> $cav.int.inf.obs$FUN
#> [1] "pk.calc.cav"
#> 
#> $cav.int.inf.obs$values
#> [1] FALSE  TRUE
#> 
#> $cav.int.inf.obs$unit_type
#> [1] "conc"
#> 
#> $cav.int.inf.obs$pretty_name
#> [1] "Cav"
#> 
#> $cav.int.inf.obs$desc
#> [1] "The average concentration during an interval (calculated with AUCint.inf.obs)"
#> 
#> $cav.int.inf.obs$sparse
#> [1] FALSE
#> 
#> $cav.int.inf.obs$formalsmap
#> $cav.int.inf.obs$formalsmap$auc
#> [1] "aucint.inf.obs"
#> 
#> 
#> $cav.int.inf.obs$depends
#> [1] "aucint.inf.obs"
#> 
#> $cav.int.inf.obs$datatype
#> [1] "interval"
#> 
#> $cav.int.inf.obs$pptestcd_cdisc
#> [1] "CAVGINO"
#> 
#> $cav.int.inf.obs$pptest_cdisc
#> [1] "Cavg Infinity Obs"
#> 
#> 
#> $cav.int.inf.pred
#> $cav.int.inf.pred$FUN
#> [1] "pk.calc.cav"
#> 
#> $cav.int.inf.pred$values
#> [1] FALSE  TRUE
#> 
#> $cav.int.inf.pred$unit_type
#> [1] "conc"
#> 
#> $cav.int.inf.pred$pretty_name
#> [1] "Cav"
#> 
#> $cav.int.inf.pred$desc
#> [1] "The average concentration during an interval (calculated with AUCint.inf.pred)"
#> 
#> $cav.int.inf.pred$sparse
#> [1] FALSE
#> 
#> $cav.int.inf.pred$formalsmap
#> $cav.int.inf.pred$formalsmap$auc
#> [1] "aucint.inf.pred"
#> 
#> 
#> $cav.int.inf.pred$depends
#> [1] "aucint.inf.pred"
#> 
#> $cav.int.inf.pred$datatype
#> [1] "interval"
#> 
#> $cav.int.inf.pred$pptestcd_cdisc
#> [1] "CAVGINP"
#> 
#> $cav.int.inf.pred$pptest_cdisc
#> [1] "Cavg Infinity Pred"
#> 
#> 
#> $thalf.eff.obs
#> $thalf.eff.obs$FUN
#> [1] "pk.calc.thalf.eff"
#> 
#> $thalf.eff.obs$values
#> [1] FALSE  TRUE
#> 
#> $thalf.eff.obs$unit_type
#> [1] "time"
#> 
#> $thalf.eff.obs$pretty_name
#> [1] "Effective half-life (based on MRT,obs)"
#> 
#> $thalf.eff.obs$desc
#> [1] "The effective half-life (as determined from the MRTobs)"
#> 
#> $thalf.eff.obs$sparse
#> [1] FALSE
#> 
#> $thalf.eff.obs$formalsmap
#> $thalf.eff.obs$formalsmap$mrt
#> [1] "mrt.obs"
#> 
#> 
#> $thalf.eff.obs$depends
#> [1] "mrt.obs"
#> 
#> $thalf.eff.obs$datatype
#> [1] "interval"
#> 
#> $thalf.eff.obs$pptestcd_cdisc
#> [1] "EFFOHL"
#> 
#> $thalf.eff.obs$pptest_cdisc
#> [1] "Effective Half-Life Obs"
#> 
#> 
#> $thalf.eff.pred
#> $thalf.eff.pred$FUN
#> [1] "pk.calc.thalf.eff"
#> 
#> $thalf.eff.pred$values
#> [1] FALSE  TRUE
#> 
#> $thalf.eff.pred$unit_type
#> [1] "time"
#> 
#> $thalf.eff.pred$pretty_name
#> [1] "Effective half-life (based on MRT,pred)"
#> 
#> $thalf.eff.pred$desc
#> [1] "The effective half-life (as determined from the MRTpred)"
#> 
#> $thalf.eff.pred$sparse
#> [1] FALSE
#> 
#> $thalf.eff.pred$formalsmap
#> $thalf.eff.pred$formalsmap$mrt
#> [1] "mrt.pred"
#> 
#> 
#> $thalf.eff.pred$depends
#> [1] "mrt.pred"
#> 
#> $thalf.eff.pred$datatype
#> [1] "interval"
#> 
#> $thalf.eff.pred$pptestcd_cdisc
#> [1] "EFFPHL"
#> 
#> $thalf.eff.pred$pptest_cdisc
#> [1] "Effective Half-Life Pred"
#> 
#> 
#> $thalf.eff.iv.obs
#> $thalf.eff.iv.obs$FUN
#> [1] "pk.calc.thalf.eff"
#> 
#> $thalf.eff.iv.obs$values
#> [1] FALSE  TRUE
#> 
#> $thalf.eff.iv.obs$unit_type
#> [1] "time"
#> 
#> $thalf.eff.iv.obs$pretty_name
#> [1] "Effective half-life (for IV dosing, based on MRT,obs)"
#> 
#> $thalf.eff.iv.obs$desc
#> [1] "The effective half-life (as determined from the intravenous MRTobs)"
#> 
#> $thalf.eff.iv.obs$sparse
#> [1] FALSE
#> 
#> $thalf.eff.iv.obs$formalsmap
#> $thalf.eff.iv.obs$formalsmap$mrt
#> [1] "mrt.iv.obs"
#> 
#> 
#> $thalf.eff.iv.obs$depends
#> [1] "mrt.iv.obs"
#> 
#> $thalf.eff.iv.obs$datatype
#> [1] "interval"
#> 
#> $thalf.eff.iv.obs$pptestcd_cdisc
#> [1] "EFFIVOHL"
#> 
#> $thalf.eff.iv.obs$pptest_cdisc
#> [1] "Effective Half-Life (for IV dosing, based on MRT Obs)"
#> 
#> 
#> $thalf.eff.iv.pred
#> $thalf.eff.iv.pred$FUN
#> [1] "pk.calc.thalf.eff"
#> 
#> $thalf.eff.iv.pred$values
#> [1] FALSE  TRUE
#> 
#> $thalf.eff.iv.pred$unit_type
#> [1] "time"
#> 
#> $thalf.eff.iv.pred$pretty_name
#> [1] "Effective half-life (for IV dosing, based on MRT,pred)"
#> 
#> $thalf.eff.iv.pred$desc
#> [1] "The effective half-life (as determined from the intravenous MRTpred)"
#> 
#> $thalf.eff.iv.pred$sparse
#> [1] FALSE
#> 
#> $thalf.eff.iv.pred$formalsmap
#> $thalf.eff.iv.pred$formalsmap$mrt
#> [1] "mrt.iv.pred"
#> 
#> 
#> $thalf.eff.iv.pred$depends
#> [1] "mrt.iv.pred"
#> 
#> $thalf.eff.iv.pred$datatype
#> [1] "interval"
#> 
#> $thalf.eff.iv.pred$pptestcd_cdisc
#> [1] "EFFIVPHL"
#> 
#> $thalf.eff.iv.pred$pptest_cdisc
#> [1] "Effective Half-Life (for IV dosing, based on MRT Pred)"
#> 
#> 
#> $kel.obs
#> $kel.obs$FUN
#> [1] "pk.calc.kel"
#> 
#> $kel.obs$values
#> [1] FALSE  TRUE
#> 
#> $kel.obs$unit_type
#> [1] "inverse_time"
#> 
#> $kel.obs$pretty_name
#> [1] "Kel (based on AUCinf,obs)"
#> 
#> $kel.obs$desc
#> [1] "Elimination rate (as calculated from the MRT with observed Clast)"
#> 
#> $kel.obs$sparse
#> [1] FALSE
#> 
#> $kel.obs$formalsmap
#> $kel.obs$formalsmap$mrt
#> [1] "mrt.obs"
#> 
#> 
#> $kel.obs$depends
#> [1] "mrt.obs"
#> 
#> $kel.obs$datatype
#> [1] "interval"
#> 
#> $kel.obs$pptestcd_cdisc
#> [1] "KELOS"
#> 
#> $kel.obs$pptest_cdisc
#> [1] "Kel (based on AUCinf,obs)"
#> 
#> 
#> $kel.pred
#> $kel.pred$FUN
#> [1] "pk.calc.kel"
#> 
#> $kel.pred$values
#> [1] FALSE  TRUE
#> 
#> $kel.pred$unit_type
#> [1] "inverse_time"
#> 
#> $kel.pred$pretty_name
#> [1] "Kel (based on AUCinf,pred)"
#> 
#> $kel.pred$desc
#> [1] "Elimination rate (as calculated from the MRT with predicted Clast)"
#> 
#> $kel.pred$sparse
#> [1] FALSE
#> 
#> $kel.pred$formalsmap
#> $kel.pred$formalsmap$mrt
#> [1] "mrt.pred"
#> 
#> 
#> $kel.pred$depends
#> [1] "mrt.pred"
#> 
#> $kel.pred$datatype
#> [1] "interval"
#> 
#> $kel.pred$pptestcd_cdisc
#> [1] "KELP"
#> 
#> $kel.pred$pptest_cdisc
#> [1] "Kel (based on AUCinf,pred)"
#> 
#> 
#> $kel.iv.obs
#> $kel.iv.obs$FUN
#> [1] "pk.calc.kel"
#> 
#> $kel.iv.obs$values
#> [1] FALSE  TRUE
#> 
#> $kel.iv.obs$unit_type
#> [1] "inverse_time"
#> 
#> $kel.iv.obs$pretty_name
#> [1] "Kel (for IV dosing, based on AUCinf,obs)"
#> 
#> $kel.iv.obs$desc
#> [1] "Elimination rate (as calculated from the intravenous MRTobs)"
#> 
#> $kel.iv.obs$sparse
#> [1] FALSE
#> 
#> $kel.iv.obs$formalsmap
#> $kel.iv.obs$formalsmap$mrt
#> [1] "mrt.iv.obs"
#> 
#> 
#> $kel.iv.obs$depends
#> [1] "mrt.iv.obs"
#> 
#> $kel.iv.obs$datatype
#> [1] "interval"
#> 
#> $kel.iv.obs$pptestcd_cdisc
#> [1] "KELIVOS"
#> 
#> $kel.iv.obs$pptest_cdisc
#> [1] "Kel (for IV dosing, based on AUCinf,obs)"
#> 
#> 
#> $kel.iv.pred
#> $kel.iv.pred$FUN
#> [1] "pk.calc.kel"
#> 
#> $kel.iv.pred$values
#> [1] FALSE  TRUE
#> 
#> $kel.iv.pred$unit_type
#> [1] "inverse_time"
#> 
#> $kel.iv.pred$pretty_name
#> [1] "Kel (for IV dosing, based on AUCinf,pred)"
#> 
#> $kel.iv.pred$desc
#> [1] "Elimination rate (as calculated from the intravenous MRTpred)"
#> 
#> $kel.iv.pred$sparse
#> [1] FALSE
#> 
#> $kel.iv.pred$formalsmap
#> $kel.iv.pred$formalsmap$mrt
#> [1] "mrt.iv.pred"
#> 
#> 
#> $kel.iv.pred$depends
#> [1] "mrt.iv.pred"
#> 
#> $kel.iv.pred$datatype
#> [1] "interval"
#> 
#> $kel.iv.pred$pptestcd_cdisc
#> [1] "KELIVP"
#> 
#> $kel.iv.pred$pptest_cdisc
#> [1] "Kel (for IV dosing, based on AUCinf,pred)"
#> 
#> 
#> $kel.int.inf.obs
#> $kel.int.inf.obs$FUN
#> [1] "pk.calc.kel"
#> 
#> $kel.int.inf.obs$values
#> [1] FALSE  TRUE
#> 
#> $kel.int.inf.obs$unit_type
#> [1] "inverse_time"
#> 
#> $kel.int.inf.obs$pretty_name
#> [1] "Kel (based on AUCint.inf.obs)"
#> 
#> $kel.int.inf.obs$desc
#> [1] "Elimination rate (as calculated from the MRTint.inf.obs)"
#> 
#> $kel.int.inf.obs$sparse
#> [1] FALSE
#> 
#> $kel.int.inf.obs$formalsmap
#> $kel.int.inf.obs$formalsmap$mrt
#> [1] "mrt.int.inf.obs"
#> 
#> 
#> $kel.int.inf.obs$depends
#> [1] "mrt.int.inf.obs"
#> 
#> $kel.int.inf.obs$datatype
#> [1] "interval"
#> 
#> $kel.int.inf.obs$pptestcd_cdisc
#> [1] "kel.int.inf.obs"
#> 
#> $kel.int.inf.obs$pptest_cdisc
#> [1] "Elimination rate (as calculated from the MRTint.inf.obs)"
#> 
#> 
#> $kel.int.inf.pred
#> $kel.int.inf.pred$FUN
#> [1] "pk.calc.kel"
#> 
#> $kel.int.inf.pred$values
#> [1] FALSE  TRUE
#> 
#> $kel.int.inf.pred$unit_type
#> [1] "inverse_time"
#> 
#> $kel.int.inf.pred$pretty_name
#> [1] "Kel (based on AUCint.inf.pred)"
#> 
#> $kel.int.inf.pred$desc
#> [1] "Elimination rate (as calculated from the MRTint.inf.pred)"
#> 
#> $kel.int.inf.pred$sparse
#> [1] FALSE
#> 
#> $kel.int.inf.pred$formalsmap
#> $kel.int.inf.pred$formalsmap$mrt
#> [1] "mrt.int.inf.pred"
#> 
#> 
#> $kel.int.inf.pred$depends
#> [1] "mrt.int.inf.pred"
#> 
#> $kel.int.inf.pred$datatype
#> [1] "interval"
#> 
#> $kel.int.inf.pred$pptestcd_cdisc
#> [1] "kel.int.inf.pred"
#> 
#> $kel.int.inf.pred$pptest_cdisc
#> [1] "Elimination rate (as calculated from the MRTint.inf.pred)"
#> 
#> 
#> $auclast.dn
#> $auclast.dn$FUN
#> [1] "pk.calc.dn"
#> 
#> $auclast.dn$values
#> [1] FALSE  TRUE
#> 
#> $auclast.dn$unit_type
#> [1] "auc_dosenorm"
#> 
#> $auclast.dn$pretty_name
#> [1] "AUClast (dose-normalized)"
#> 
#> $auclast.dn$desc
#> [1] "Dose normalized auclast"
#> 
#> $auclast.dn$sparse
#> [1] FALSE
#> 
#> $auclast.dn$formalsmap
#> $auclast.dn$formalsmap$parameter
#> [1] "auclast"
#> 
#> 
#> $auclast.dn$depends
#> [1] "auclast"
#> 
#> $auclast.dn$datatype
#> [1] "interval"
#> 
#> $auclast.dn$pptestcd_cdisc
#> [1] "AUCLSTD"
#> 
#> $auclast.dn$pptest_cdisc
#> [1] "AUC to Last Nonzero Conc by Dose"
#> 
#> 
#> $aucall.dn
#> $aucall.dn$FUN
#> [1] "pk.calc.dn"
#> 
#> $aucall.dn$values
#> [1] FALSE  TRUE
#> 
#> $aucall.dn$unit_type
#> [1] "auc_dosenorm"
#> 
#> $aucall.dn$pretty_name
#> [1] "AUCall (dose-normalized)"
#> 
#> $aucall.dn$desc
#> [1] "Dose normalized aucall"
#> 
#> $aucall.dn$sparse
#> [1] FALSE
#> 
#> $aucall.dn$formalsmap
#> $aucall.dn$formalsmap$parameter
#> [1] "aucall"
#> 
#> 
#> $aucall.dn$depends
#> [1] "aucall"
#> 
#> $aucall.dn$datatype
#> [1] "interval"
#> 
#> $aucall.dn$pptestcd_cdisc
#> [1] "AUCALLD"
#> 
#> $aucall.dn$pptest_cdisc
#> [1] "AUC All by Dose"
#> 
#> 
#> $aucinf.obs.dn
#> $aucinf.obs.dn$FUN
#> [1] "pk.calc.dn"
#> 
#> $aucinf.obs.dn$values
#> [1] FALSE  TRUE
#> 
#> $aucinf.obs.dn$unit_type
#> [1] "auc_dosenorm"
#> 
#> $aucinf.obs.dn$pretty_name
#> [1] "AUCinf,obs (dose-normalized)"
#> 
#> $aucinf.obs.dn$desc
#> [1] "Dose normalized aucinf.obs"
#> 
#> $aucinf.obs.dn$sparse
#> [1] FALSE
#> 
#> $aucinf.obs.dn$formalsmap
#> $aucinf.obs.dn$formalsmap$parameter
#> [1] "aucinf.obs"
#> 
#> 
#> $aucinf.obs.dn$depends
#> [1] "aucinf.obs"
#> 
#> $aucinf.obs.dn$datatype
#> [1] "interval"
#> 
#> $aucinf.obs.dn$pptestcd_cdisc
#> [1] "AUCIFOD"
#> 
#> $aucinf.obs.dn$pptest_cdisc
#> [1] "AUC Infinity Obs by Dose"
#> 
#> 
#> $aucinf.pred.dn
#> $aucinf.pred.dn$FUN
#> [1] "pk.calc.dn"
#> 
#> $aucinf.pred.dn$values
#> [1] FALSE  TRUE
#> 
#> $aucinf.pred.dn$unit_type
#> [1] "auc_dosenorm"
#> 
#> $aucinf.pred.dn$pretty_name
#> [1] "AUCinf,pred (dose-normalized)"
#> 
#> $aucinf.pred.dn$desc
#> [1] "Dose normalized aucinf.pred"
#> 
#> $aucinf.pred.dn$sparse
#> [1] FALSE
#> 
#> $aucinf.pred.dn$formalsmap
#> $aucinf.pred.dn$formalsmap$parameter
#> [1] "aucinf.pred"
#> 
#> 
#> $aucinf.pred.dn$depends
#> [1] "aucinf.pred"
#> 
#> $aucinf.pred.dn$datatype
#> [1] "interval"
#> 
#> $aucinf.pred.dn$pptestcd_cdisc
#> [1] "AUCIFPD"
#> 
#> $aucinf.pred.dn$pptest_cdisc
#> [1] "AUC Infinity Pred by Dose"
#> 
#> 
#> $aumclast.dn
#> $aumclast.dn$FUN
#> [1] "pk.calc.dn"
#> 
#> $aumclast.dn$values
#> [1] FALSE  TRUE
#> 
#> $aumclast.dn$unit_type
#> [1] "aumc_dosenorm"
#> 
#> $aumclast.dn$pretty_name
#> [1] "AUMC,last (dose-normalized)"
#> 
#> $aumclast.dn$desc
#> [1] "Dose normalized aumclast"
#> 
#> $aumclast.dn$sparse
#> [1] FALSE
#> 
#> $aumclast.dn$formalsmap
#> $aumclast.dn$formalsmap$parameter
#> [1] "aumclast"
#> 
#> 
#> $aumclast.dn$depends
#> [1] "aumclast"
#> 
#> $aumclast.dn$datatype
#> [1] "interval"
#> 
#> $aumclast.dn$pptestcd_cdisc
#> [1] "AUMCLSTD"
#> 
#> $aumclast.dn$pptest_cdisc
#> [1] "AUMC to Last Nonzero Conc by Dose"
#> 
#> 
#> $aumcall.dn
#> $aumcall.dn$FUN
#> [1] "pk.calc.dn"
#> 
#> $aumcall.dn$values
#> [1] FALSE  TRUE
#> 
#> $aumcall.dn$unit_type
#> [1] "aumc_dosenorm"
#> 
#> $aumcall.dn$pretty_name
#> [1] "AUMC,all (dose-normalized)"
#> 
#> $aumcall.dn$desc
#> [1] "Dose normalized aumcall"
#> 
#> $aumcall.dn$sparse
#> [1] FALSE
#> 
#> $aumcall.dn$formalsmap
#> $aumcall.dn$formalsmap$parameter
#> [1] "aumcall"
#> 
#> 
#> $aumcall.dn$depends
#> [1] "aumcall"
#> 
#> $aumcall.dn$datatype
#> [1] "interval"
#> 
#> $aumcall.dn$pptestcd_cdisc
#> [1] "AUMCALLD"
#> 
#> $aumcall.dn$pptest_cdisc
#> [1] "AUMC All by Dose"
#> 
#> 
#> $aumcinf.obs.dn
#> $aumcinf.obs.dn$FUN
#> [1] "pk.calc.dn"
#> 
#> $aumcinf.obs.dn$values
#> [1] FALSE  TRUE
#> 
#> $aumcinf.obs.dn$unit_type
#> [1] "aumc_dosenorm"
#> 
#> $aumcinf.obs.dn$pretty_name
#> [1] "AUMC,inf,obs (dose-normalized)"
#> 
#> $aumcinf.obs.dn$desc
#> [1] "Dose normalized aumcinf.obs"
#> 
#> $aumcinf.obs.dn$sparse
#> [1] FALSE
#> 
#> $aumcinf.obs.dn$formalsmap
#> $aumcinf.obs.dn$formalsmap$parameter
#> [1] "aumcinf.obs"
#> 
#> 
#> $aumcinf.obs.dn$depends
#> [1] "aumcinf.obs"
#> 
#> $aumcinf.obs.dn$datatype
#> [1] "interval"
#> 
#> $aumcinf.obs.dn$pptestcd_cdisc
#> [1] "AUMCIFOD"
#> 
#> $aumcinf.obs.dn$pptest_cdisc
#> [1] "AUMC Infinity Obs by Dose"
#> 
#> 
#> $aumcinf.pred.dn
#> $aumcinf.pred.dn$FUN
#> [1] "pk.calc.dn"
#> 
#> $aumcinf.pred.dn$values
#> [1] FALSE  TRUE
#> 
#> $aumcinf.pred.dn$unit_type
#> [1] "aumc_dosenorm"
#> 
#> $aumcinf.pred.dn$pretty_name
#> [1] "AUMC,inf,pred (dose-normalized)"
#> 
#> $aumcinf.pred.dn$desc
#> [1] "Dose normalized aumcinf.pred"
#> 
#> $aumcinf.pred.dn$sparse
#> [1] FALSE
#> 
#> $aumcinf.pred.dn$formalsmap
#> $aumcinf.pred.dn$formalsmap$parameter
#> [1] "aumcinf.pred"
#> 
#> 
#> $aumcinf.pred.dn$depends
#> [1] "aumcinf.pred"
#> 
#> $aumcinf.pred.dn$datatype
#> [1] "interval"
#> 
#> $aumcinf.pred.dn$pptestcd_cdisc
#> [1] "AUMCIFPD"
#> 
#> $aumcinf.pred.dn$pptest_cdisc
#> [1] "AUMC Infinity Pred by Dose"
#> 
#> 
#> $cmax.dn
#> $cmax.dn$FUN
#> [1] "pk.calc.dn"
#> 
#> $cmax.dn$values
#> [1] FALSE  TRUE
#> 
#> $cmax.dn$unit_type
#> [1] "conc_dosenorm"
#> 
#> $cmax.dn$pretty_name
#> [1] "Cmax (dose-normalized)"
#> 
#> $cmax.dn$desc
#> [1] "Dose normalized cmax"
#> 
#> $cmax.dn$sparse
#> [1] FALSE
#> 
#> $cmax.dn$formalsmap
#> $cmax.dn$formalsmap$parameter
#> [1] "cmax"
#> 
#> 
#> $cmax.dn$depends
#> [1] "cmax"
#> 
#> $cmax.dn$datatype
#> [1] "interval"
#> 
#> $cmax.dn$pptestcd_cdisc
#> [1] "CMAXD"
#> 
#> $cmax.dn$pptest_cdisc
#> [1] "Max Conc by Dose"
#> 
#> 
#> $cmin.dn
#> $cmin.dn$FUN
#> [1] "pk.calc.dn"
#> 
#> $cmin.dn$values
#> [1] FALSE  TRUE
#> 
#> $cmin.dn$unit_type
#> [1] "conc_dosenorm"
#> 
#> $cmin.dn$pretty_name
#> [1] "Cmin (dose-normalized)"
#> 
#> $cmin.dn$desc
#> [1] "Dose normalized cmin"
#> 
#> $cmin.dn$sparse
#> [1] FALSE
#> 
#> $cmin.dn$formalsmap
#> $cmin.dn$formalsmap$parameter
#> [1] "cmin"
#> 
#> 
#> $cmin.dn$depends
#> [1] "cmin"
#> 
#> $cmin.dn$datatype
#> [1] "interval"
#> 
#> $cmin.dn$pptestcd_cdisc
#> [1] "CMIND"
#> 
#> $cmin.dn$pptest_cdisc
#> [1] "Min Conc by Dose"
#> 
#> 
#> $clast.obs.dn
#> $clast.obs.dn$FUN
#> [1] "pk.calc.dn"
#> 
#> $clast.obs.dn$values
#> [1] FALSE  TRUE
#> 
#> $clast.obs.dn$unit_type
#> [1] "conc_dosenorm"
#> 
#> $clast.obs.dn$pretty_name
#> [1] "Clast (dose-normalized)"
#> 
#> $clast.obs.dn$desc
#> [1] "Dose normalized clast.obs"
#> 
#> $clast.obs.dn$sparse
#> [1] FALSE
#> 
#> $clast.obs.dn$formalsmap
#> $clast.obs.dn$formalsmap$parameter
#> [1] "clast.obs"
#> 
#> 
#> $clast.obs.dn$depends
#> [1] "clast.obs"
#> 
#> $clast.obs.dn$datatype
#> [1] "interval"
#> 
#> $clast.obs.dn$pptestcd_cdisc
#> [1] "CLSTD"
#> 
#> $clast.obs.dn$pptest_cdisc
#> [1] "Last Nonzero Conc by Dose"
#> 
#> 
#> $clast.pred.dn
#> $clast.pred.dn$FUN
#> [1] "pk.calc.dn"
#> 
#> $clast.pred.dn$values
#> [1] FALSE  TRUE
#> 
#> $clast.pred.dn$unit_type
#> [1] "conc_dosenorm"
#> 
#> $clast.pred.dn$pretty_name
#> [1] "Clast,pred (dose-normalized)"
#> 
#> $clast.pred.dn$desc
#> [1] "Dose normalized clast.pred"
#> 
#> $clast.pred.dn$sparse
#> [1] FALSE
#> 
#> $clast.pred.dn$formalsmap
#> $clast.pred.dn$formalsmap$parameter
#> [1] "clast.pred"
#> 
#> 
#> $clast.pred.dn$depends
#> [1] "clast.pred"
#> 
#> $clast.pred.dn$datatype
#> [1] "interval"
#> 
#> $clast.pred.dn$pptestcd_cdisc
#> [1] "CLSTPD"
#> 
#> $clast.pred.dn$pptest_cdisc
#> [1] "Clast pred by Dose"
#> 
#> 
#> $cav.dn
#> $cav.dn$FUN
#> [1] "pk.calc.dn"
#> 
#> $cav.dn$values
#> [1] FALSE  TRUE
#> 
#> $cav.dn$unit_type
#> [1] "conc_dosenorm"
#> 
#> $cav.dn$pretty_name
#> [1] "Cav (dose-normalized)"
#> 
#> $cav.dn$desc
#> [1] "Dose normalized cav"
#> 
#> $cav.dn$sparse
#> [1] FALSE
#> 
#> $cav.dn$formalsmap
#> $cav.dn$formalsmap$parameter
#> [1] "cav"
#> 
#> 
#> $cav.dn$depends
#> [1] "cav"
#> 
#> $cav.dn$datatype
#> [1] "interval"
#> 
#> $cav.dn$pptestcd_cdisc
#> [1] "CAVGD"
#> 
#> $cav.dn$pptest_cdisc
#> [1] "Average Conc by Dose"
#> 
#> 
#> $ctrough.dn
#> $ctrough.dn$FUN
#> [1] "pk.calc.dn"
#> 
#> $ctrough.dn$values
#> [1] FALSE  TRUE
#> 
#> $ctrough.dn$unit_type
#> [1] "conc_dosenorm"
#> 
#> $ctrough.dn$pretty_name
#> [1] "Ctrough (dose-normalized)"
#> 
#> $ctrough.dn$desc
#> [1] "Dose normalized ctrough"
#> 
#> $ctrough.dn$sparse
#> [1] FALSE
#> 
#> $ctrough.dn$formalsmap
#> $ctrough.dn$formalsmap$parameter
#> [1] "ctrough"
#> 
#> 
#> $ctrough.dn$depends
#> [1] "ctrough"
#> 
#> $ctrough.dn$datatype
#> [1] "interval"
#> 
#> $ctrough.dn$pptestcd_cdisc
#> [1] "CTROUGHD"
#> 
#> $ctrough.dn$pptest_cdisc
#> [1] "Conc Trough by Dose"
#> 
#> 
#> $clr.last.dn
#> $clr.last.dn$FUN
#> [1] "pk.calc.dn"
#> 
#> $clr.last.dn$values
#> [1] FALSE  TRUE
#> 
#> $clr.last.dn$unit_type
#> [1] "renal_clearance_dosenorm"
#> 
#> $clr.last.dn$pretty_name
#> [1] "Renal clearance (from AUClast) (dose-normalized)"
#> 
#> $clr.last.dn$desc
#> [1] "Dose normalized clr.last"
#> 
#> $clr.last.dn$sparse
#> [1] FALSE
#> 
#> $clr.last.dn$formalsmap
#> $clr.last.dn$formalsmap$parameter
#> [1] "clr.last"
#> 
#> 
#> $clr.last.dn$depends
#> [1] "clr.last"
#> 
#> $clr.last.dn$datatype
#> [1] "interval"
#> 
#> $clr.last.dn$pptestcd_cdisc
#> [1] "RENALCLD"
#> 
#> $clr.last.dn$pptest_cdisc
#> [1] "Renal CL by Dose"
#> 
#> 
#> $clr.obs.dn
#> $clr.obs.dn$FUN
#> [1] "pk.calc.dn"
#> 
#> $clr.obs.dn$values
#> [1] FALSE  TRUE
#> 
#> $clr.obs.dn$unit_type
#> [1] "renal_clearance_dosenorm"
#> 
#> $clr.obs.dn$pretty_name
#> [1] "Renal clearance (from AUCinf,obs) (dose-normalized)"
#> 
#> $clr.obs.dn$desc
#> [1] "Dose normalized clr.obs"
#> 
#> $clr.obs.dn$sparse
#> [1] FALSE
#> 
#> $clr.obs.dn$formalsmap
#> $clr.obs.dn$formalsmap$parameter
#> [1] "clr.obs"
#> 
#> 
#> $clr.obs.dn$depends
#> [1] "clr.obs"
#> 
#> $clr.obs.dn$datatype
#> [1] "interval"
#> 
#> $clr.obs.dn$pptestcd_cdisc
#> [1] "RENALCLD"
#> 
#> $clr.obs.dn$pptest_cdisc
#> [1] "Renal CL by Dose"
#> 
#> 
#> $clr.pred.dn
#> $clr.pred.dn$FUN
#> [1] "pk.calc.dn"
#> 
#> $clr.pred.dn$values
#> [1] FALSE  TRUE
#> 
#> $clr.pred.dn$unit_type
#> [1] "renal_clearance_dosenorm"
#> 
#> $clr.pred.dn$pretty_name
#> [1] "Renal clearance (from AUCinf,pred) (dose-normalized)"
#> 
#> $clr.pred.dn$desc
#> [1] "Dose normalized clr.pred"
#> 
#> $clr.pred.dn$sparse
#> [1] FALSE
#> 
#> $clr.pred.dn$formalsmap
#> $clr.pred.dn$formalsmap$parameter
#> [1] "clr.pred"
#> 
#> 
#> $clr.pred.dn$depends
#> [1] "clr.pred"
#> 
#> $clr.pred.dn$datatype
#> [1] "interval"
#> 
#> $clr.pred.dn$pptestcd_cdisc
#> [1] "RENALCLD"
#> 
#> $clr.pred.dn$pptest_cdisc
#> [1] "Renal CL by Dose"
#> 
#>