Clean up the time to steady-state parameters and return a data frame for use by the tss calculators.

Usage

pk.tss.data.prep(
  conc,
  time,
  subject,
  treatment,
  subject.dosing,
  time.dosing,
  options = list(),
  conc.blq = NULL,
  conc.na = NULL,
  check = TRUE,
  ...
)

Arguments

conc: Measured concentrations
time: Time of the measurement of the concentrations
subject: Subject identifiers (used as a random effect in the model)
treatment: Treatment description (if missing, all subjects are assumed to be on the same treatment)
subject.dosing: Subject number for dosing
time.dosing: Time of dosing
options: List of changes to the default PKNCA options (see PKNCA.options())
conc.blq: See clean.conc.blq()
conc.na: See clean.conc.na()
check: Run assert_conc_time()?
...: Discarded inputs to allow generic calls between tss methods.

Value

a data frame with columns for concentration, time, subject, and treatment.