Determine time at or above a set value — pk.calc.time

Interpolation is performed aligning with PKNCA.options("auc.method"). Extrapolation outside of the measured times is not yet implemented. The method may be changed by giving a named method argument, as well.

Usage

pk.calc.time_above(conc, time, conc_above, ..., options = list(), check = TRUE)

Arguments

conc: Measured concentrations
time: Time of the measurement of the concentrations
conc_above: The concentration to be above
...: Extra arguments. Currently, the only extra argument that is used is method as described in the details section.
options: List of changes to the default PKNCA options (see PKNCA.options())
check: Run assert_conc_time(), clean.conc.blq(), and clean.conc.na()?

Value

the time above the given concentration

Details

For 'lin up/log down', if clast is above conc_above and there are concentrations BLQ after that, linear down is used to extrapolate to the BLQ concentration (equivalent to AUCall).