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Determine the degree of fluctuation

Usage

pk.calc.deg.fluc(cmax, cmin, cav)

pk.calc.swing(cmax, cmin)

Arguments

cmax

The maximum observed concentration

cmin

The minimum observed concentration

cav

The average concentration in the interval

Value

The degree of fluctuation around the average concentration.

The swing above the minimum concentration. If cmin is zero, then the result is infinity.

Details

deg.fluc is 100*(cmax - cmin)/cav.

swing is 100*(cmax - cmin)/cmin.

Functions

  • pk.calc.swing(): PK swing

See also

Other Multiple-dose PK parameters: pk.calc.ptr()